메뉴 건너뛰기




Volumn 43, Issue 9, 2015, Pages 4365-4380

The many faces of Dicer: The complexity of the mechanisms regulating Dicer gene expression and enzyme activities

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MESSENGER RNA; DEAD BOX PROTEIN; DICER1 PROTEIN, HUMAN; RIBONUCLEASE III;

EID: 84935920791     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv328     Document Type: Article
Times cited : (86)

References (194)
  • 1
    • 0038343499 scopus 로고    scopus 로고
    • MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing
    • Ambros, V. (2003) MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing. Cell, 113, 673-676.
    • (2003) Cell , vol.113 , pp. 673-676
    • Ambros, V.1
  • 2
    • 33644857025 scopus 로고    scopus 로고
    • Gene regulation by microRNAs
    • Carthew, R.W. (2006) Gene regulation by microRNAs. Curr. Opin. Genet. Dev., 16, 203-208.
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 203-208
    • Carthew, R.W.1
  • 3
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • Kim, V.N. (2005) MicroRNA biogenesis: Coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol., 6, 376-385.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 4
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman, R.C., Farh, K.K., Burge, C.B. and Bartel, D.P. (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res., 19, 92-105.
    • (2009) Genome Res. , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 5
    • 75649089283 scopus 로고    scopus 로고
    • Sequence-non-specific effects of RNA interference triggers and microRNA regulators
    • Olejniczak, M., Galka, P. and Krzyzosiak, W.J. (2009) Sequence-non-specific effects of RNA interference triggers and microRNA regulators. Nucleic Acids Res., 38, 1-16.
    • (2009) Nucleic Acids Res. , vol.38 , pp. 1-16
    • Olejniczak, M.1    Galka, P.2    Krzyzosiak, W.J.3
  • 6
    • 33646745522 scopus 로고    scopus 로고
    • The interplay between virus infection and the cellular RNA interference machinery
    • Berkhout, B. and Haasnoot, J. (2006) The interplay between virus infection and the cellular RNA interference machinery. FEBS Lett., 580, 2896-2902.
    • (2006) FEBS Lett. , vol.580 , pp. 2896-2902
    • Berkhout, B.1    Haasnoot, J.2
  • 8
    • 70349085411 scopus 로고    scopus 로고
    • Human-and virus-encoded microRNAs as potential targets of antiviral therapy
    • Kurzynska-Kokorniak, A., Jackowiak, P. and Figlerowicz, M. (2009) Human-and virus-encoded microRNAs as potential targets of antiviral therapy. Mini Rev. Med. Chem., 9, 927-937.
    • (2009) Mini Rev. Med. Chem. , vol.9 , pp. 927-937
    • Kurzynska-Kokorniak, A.1    Jackowiak, P.2    Figlerowicz, M.3
  • 9
    • 83455235218 scopus 로고    scopus 로고
    • Mechanisms involved in the development of chronic hepatitis C as potential targets of antiviral therapy
    • Jackowiak, P., Figlerowicz, M. and Kurzynska-Kokorniak, A. (2011) Mechanisms involved in the development of chronic hepatitis C as potential targets of antiviral therapy. Curr. Pharm. Biotechnol., 12, 1774-1780.
    • (2011) Curr. Pharm. Biotechnol. , vol.12 , pp. 1774-1780
    • Jackowiak, P.1    Figlerowicz, M.2    Kurzynska-Kokorniak, A.3
  • 10
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G.A. and Croce, C.M. (2006) MicroRNA signatures in human cancers. Nat. Rev. Cancer, 6, 857-866.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 11
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-microRNAs with a role in cancer
    • Esquela-Kerscher, A. and Slack, F.J. (2006) Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer, 6, 259-269.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 12
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microRNA network cause neurodegenerative disease
    • Hebert, S.S. and De Strooper, B. (2009) Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci., 32, 199-206.
    • (2009) Trends Neurosci. , vol.32 , pp. 199-206
    • Hebert, S.S.1    De Strooper, B.2
  • 14
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein, E., Caudy, A.A., Hammond, S.M. and Hannon, G.J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature, 409, 363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 17
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • Zhang, H., Kolb, F.A., Brondani, V., Billy, E. and Filipowicz, W. (2002) Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J., 21, 5875-5885.
    • (2002) EMBO J. , vol.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 18
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • Zhang, H., Kolb, F.A., Jaskiewicz, L., Westhof, E. and Filipowicz, W. (2004) Single processing center models for human Dicer and bacterial RNase III. Cell, 118, 57-68.
    • (2004) Cell , vol.118 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5
  • 20
    • 70349767012 scopus 로고    scopus 로고
    • Structure of the human Dicer-TRBP complex by electron microscopy
    • Lau, P.W., Potter, C.S., Carragher, B. and MacRae, I.J. (2009) Structure of the human Dicer-TRBP complex by electron microscopy. Structure, 17, 1326-1332.
    • (2009) Structure , vol.17 , pp. 1326-1332
    • Lau, P.W.1    Potter, C.S.2    Carragher, B.3    Macrae, I.J.4
  • 23
    • 84894274509 scopus 로고    scopus 로고
    • A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer
    • Tian, Y., Simanshu, D.K., Ma, J.B., Park, J.E., Heo, I., Kim, V.N. and Patel, D.J. (2014) A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer. Mol. Cell, 53, 606-616.
    • (2014) Mol. Cell , vol.53 , pp. 606-616
    • Tian, Y.1    Simanshu, D.K.2    Ma, J.B.3    Park, J.E.4    Heo, I.5    Kim, V.N.6    Patel, D.J.7
  • 24
    • 35348983404 scopus 로고    scopus 로고
    • Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer
    • Takeshita, D., Zenno, S., Lee, W.C., Nagata, K., Saigo, K. and Tanokura, M. (2007) Homodimeric structure and double-stranded RNA cleavage activity of the C-terminal RNase III domain of human dicer. J. Mol. Biol., 374, 106-120.
    • (2007) J. Mol. Biol. , vol.374 , pp. 106-120
    • Takeshita, D.1    Zenno, S.2    Lee, W.C.3    Nagata, K.4    Saigo, K.5    Tanokura, M.6
  • 25
    • 33750990797 scopus 로고    scopus 로고
    • DUF283 domain of Dicer proteins has a double-stranded RNA-binding fold
    • Dlakic, M. (2006) DUF283 domain of Dicer proteins has a double-stranded RNA-binding fold. Bioinformatics, 22, 2711-2714.
    • (2006) Bioinformatics , vol.22 , pp. 2711-2714
    • Dlakic, M.1
  • 26
    • 0345359925 scopus 로고    scopus 로고
    • Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain
    • Lingel, A., Simon, B., Izaurralde, E. and Sattler, M. (2003) Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain. Nature, 426, 465-469.
    • (2003) Nature , vol.426 , pp. 465-469
    • Lingel, A.1    Simon, B.2    Izaurralde, E.3    Sattler, M.4
  • 27
    • 2442679207 scopus 로고    scopus 로고
    • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
    • Ma, J.B., Ye, K. and Patel, D.J. (2004) Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature, 429, 318-322.
    • (2004) Nature , vol.429 , pp. 318-322
    • Ma, J.B.1    Ye, K.2    Patel, D.J.3
  • 29
    • 0642345790 scopus 로고    scopus 로고
    • Structure and conserved RNA binding of the PAZ domain
    • Yan, K.S., Yan, S., Farooq, A., Han, A., Zeng, L. and Zhou, M.M. (2003) Structure and conserved RNA binding of the PAZ domain. Nature, 426, 468-474.
    • (2003) Nature , vol.426 , pp. 468-474
    • Yan, K.S.1    Yan, S.2    Farooq, A.3    Han, A.4    Zeng, L.5    Zhou, M.M.6
  • 31
    • 84865513822 scopus 로고    scopus 로고
    • Coordinated activities of human dicer domains in regulatory RNA processing
    • Ma, E., Zhou, K., Kidwell, M.A. and Doudna, J.A. (2012) Coordinated activities of human dicer domains in regulatory RNA processing. J. Mol. Biol., 422, 466-476.
    • (2012) J. Mol. Biol. , vol.422 , pp. 466-476
    • Ma, E.1    Zhou, K.2    Kidwell, M.A.3    Doudna, J.A.4
  • 32
    • 84869037267 scopus 로고    scopus 로고
    • The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo
    • Gu, S., Jin, L., Zhang, Y., Huang, Y., Zhang, F., Valdmanis, P.N. and Kay, M.A. (2012) The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo. Cell, 151, 900-911.
    • (2012) Cell , vol.151 , pp. 900-911
    • Gu, S.1    Jin, L.2    Zhang, Y.3    Huang, Y.4    Zhang, F.5    Valdmanis, P.N.6    Kay, M.A.7
  • 34
    • 84924122348 scopus 로고    scopus 로고
    • Structure of precursor microRNA's terminal loop regulates human Dicer's dicing activity by switching DExH/D domain
    • Liu, Z., Wang, J., Li, G. and Wang, H.W. (2014) Structure of precursor microRNA's terminal loop regulates human Dicer's dicing activity by switching DExH/D domain. Protein Cell, 6, 185-193.
    • (2014) Protein Cell , vol.6 , pp. 185-193
    • Liu, Z.1    Wang, J.2    Li, G.3    Wang, H.W.4
  • 35
    • 32544460452 scopus 로고    scopus 로고
    • The role of PACT in the RNA silencing pathway
    • Lee, Y., Hur, I., Park, S.Y., Kim, Y.K., Suh, M.R. and Kim, V.N. (2006) The role of PACT in the RNA silencing pathway. EMBO J., 25, 522-532.
    • (2006) EMBO J. , vol.25 , pp. 522-532
    • Lee, Y.1    Hur, I.2    Park, S.Y.3    Kim, Y.K.4    Suh, M.R.5    Kim, V.N.6
  • 36
    • 35349023128 scopus 로고    scopus 로고
    • Functional anatomy of the Drosophila microRNA-generating enzyme
    • Ye, X., Paroo, Z. and Liu, Q. (2007) Functional anatomy of the Drosophila microRNA-generating enzyme. J. Biol. Chem., 282, 28373-28378.
    • (2007) J. Biol. Chem. , vol.282 , pp. 28373-28378
    • Ye, X.1    Paroo, Z.2    Liu, Q.3
  • 37
    • 44649136660 scopus 로고    scopus 로고
    • Autoinhibition of human dicer by its internal helicase domain
    • Ma, E., MacRae, I.J., Kirsch, J.F. and Doudna, J.A. (2008) Autoinhibition of human dicer by its internal helicase domain. J. Mol. Biol., 380, 237-243.
    • (2008) J. Mol. Biol. , vol.380 , pp. 237-243
    • Ma, E.1    Macrae, I.J.2    Kirsch, J.F.3    Doudna, J.A.4
  • 38
    • 33745951984 scopus 로고    scopus 로고
    • On the origin and functions of RNA-mediated silencing: From protists to man
    • Cerutti, H. and Casas-Mollano, J.A. (2006) On the origin and functions of RNA-mediated silencing: From protists to man. Curr. Genet., 50, 81-99.
    • (2006) Curr. Genet. , vol.50 , pp. 81-99
    • Cerutti, H.1    Casas-Mollano, J.A.2
  • 39
    • 84873606896 scopus 로고    scopus 로고
    • Evolution of animal and plant dicers: Early parallel duplications and recurrent adaptation of antiviral RNA binding in plants
    • Mukherjee, K., Campos, H. and Kolaczkowski, B. (2012) Evolution of animal and plant dicers: Early parallel duplications and recurrent adaptation of antiviral RNA binding in plants. Mol. Biol. Evol., 30, 627-641.
    • (2012) Mol. Biol. Evol. , vol.30 , pp. 627-641
    • Mukherjee, K.1    Campos, H.2    Kolaczkowski, B.3
  • 40
    • 80052956817 scopus 로고    scopus 로고
    • Compatibility with killer explains the rise of RNAi-deficient fungi
    • Drinnenberg, I.A., Fink, G.R. and Bartel, D.P. (2011) Compatibility with killer explains the rise of RNAi-deficient fungi. Science, 333, 1592.
    • (2011) Science , vol.333 , pp. 1592
    • Drinnenberg, I.A.1    Fink, G.R.2    Bartel, D.P.3
  • 41
    • 84875082069 scopus 로고    scopus 로고
    • Loss and retention of RNA interference in fungi and parasites
    • Nicolas, F.E., Torres-Martinez, S. and Ruiz-Vazquez, R.M. (2013) Loss and retention of RNA interference in fungi and parasites. PLoS Pathog., 9, e1003089.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003089
    • Nicolas, F.E.1    Torres-Martinez, S.2    Ruiz-Vazquez, R.M.3
  • 42
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Lee, Y.S., Nakahara, K., Pham, J.W., Kim, K., He, Z., Sontheimer, E.J. and Carthew, R.W. (2004) Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell, 117, 69-81.
    • (2004) Cell , vol.117 , pp. 69-81
    • Lee, Y.S.1    Nakahara, K.2    Pham, J.W.3    Kim, K.4    He, Z.5    Sontheimer, E.J.6    Carthew, R.W.7
  • 44
    • 33744494279 scopus 로고    scopus 로고
    • Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila
    • Galiana-Arnoux, D., Dostert, C., Schneemann, A., Hoffmann, J.A. and Imler, J.L. (2006) Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila. Nat. Immunol., 7, 590-597.
    • (2006) Nat. Immunol. , vol.7 , pp. 590-597
    • Galiana-Arnoux, D.1    Dostert, C.2    Schneemann, A.3    Hoffmann, J.A.4    Imler, J.L.5
  • 45
  • 46
    • 33644801773 scopus 로고    scopus 로고
    • Alternative initiation and splicing in dicer gene expression in human breast cells
    • Irvin-Wilson, C.V. and Chaudhuri, G. (2005) Alternative initiation and splicing in dicer gene expression in human breast cells. Breast Cancer Res., 7, R563-R569.
    • (2005) Breast Cancer Res. , vol.7 , pp. R563-R569
    • Irvin-Wilson, C.V.1    Chaudhuri, G.2
  • 47
    • 84876944802 scopus 로고    scopus 로고
    • Sox4-mediated Dicer expression is critical for suppression of melanoma cell invasion
    • Jafarnejad, S.M., Ardekani, G.S., Ghaffari, M., Martinka, M. and Li, G. (2013) Sox4-mediated Dicer expression is critical for suppression of melanoma cell invasion. Oncogene, 32, 2131-2139.
    • (2013) Oncogene , vol.32 , pp. 2131-2139
    • Jafarnejad, S.M.1    Ardekani, G.S.2    Ghaffari, M.3    Martinka, M.4    Li, G.5
  • 54
    • 78449297894 scopus 로고    scopus 로고
    • The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network
    • Boominathan, L. (2010) The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network. Cancer Metastasis. Rev., 29, 613-639.
    • (2010) Cancer Metastasis. Rev. , vol.29 , pp. 613-639
    • Boominathan, L.1
  • 55
    • 60949102130 scopus 로고    scopus 로고
    • Dicer is regulated by cellular stresses and interferons
    • Wiesen, J.L. and Tomasi, T.B. (2009) Dicer is regulated by cellular stresses and interferons. Mol. Immunol., 46, 1222-1228.
    • (2009) Mol. Immunol. , vol.46 , pp. 1222-1228
    • Wiesen, J.L.1    Tomasi, T.B.2
  • 57
    • 84883816842 scopus 로고    scopus 로고
    • Guided by RNAs: X-inactivation as a model for lncRNA function
    • Froberg, J.E., Yang, L. and Lee, J.T. (2013) Guided by RNAs: X-inactivation as a model for lncRNA function. J. Mol. Biol., 425, 3698-3706.
    • (2013) J. Mol. Biol. , vol.425 , pp. 3698-3706
    • Froberg, J.E.1    Yang, L.2    Lee, J.T.3
  • 58
    • 0033979493 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase
    • Matsuda, S., Ichigotani, Y., Okuda, T., Irimura, T., Nakatsugawa, S. and Hamaguchi, M. (2000) Molecular cloning and characterization of a novel human gene (HERNA) which encodes a putative RNA-helicase. Biochim. Biophys. Acta, 1490, 163-169.
    • (2000) Biochim. Biophys. Acta , vol.1490 , pp. 163-169
    • Matsuda, S.1    Ichigotani, Y.2    Okuda, T.3    Irimura, T.4    Nakatsugawa, S.5    Hamaguchi, M.6
  • 60
    • 78751575937 scopus 로고    scopus 로고
    • Complexity in the regulation of Dicer expression: Dicer variant proteins are differentially expressed in epithelial and mesenchymal breast cancer cells and decreased during EMT
    • Hinkal, G.W., Grelier, G., Puisieux, A. and Moyret-Lalle, C. (2011) Complexity in the regulation of Dicer expression: Dicer variant proteins are differentially expressed in epithelial and mesenchymal breast cancer cells and decreased during EMT. Br. J. Cancer, 104, 387-388.
    • (2011) Br. J. Cancer , vol.104 , pp. 387-388
    • Hinkal, G.W.1    Grelier, G.2    Puisieux, A.3    Moyret-Lalle, C.4
  • 61
    • 77955272115 scopus 로고    scopus 로고
    • A novel splice variant of the human dicer gene is expressed in neuroblastoma cells
    • Potenza, N., Papa, U., Scaruffi, P., Mosca, N., Tonini, G.P. and Russo, A. (2010) A novel splice variant of the human dicer gene is expressed in neuroblastoma cells. FEBS Lett., 584, 3452-3457.
    • (2010) FEBS Lett. , vol.584 , pp. 3452-3457
    • Potenza, N.1    Papa, U.2    Scaruffi, P.3    Mosca, N.4    Tonini, G.P.5    Russo, A.6
  • 62
    • 84861391272 scopus 로고    scopus 로고
    • Vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs
    • Gurtan, A.M., Lu, V., Bhutkar, A. and Sharp, P.A. (2012) In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs. RNA, 18, 1116-1122.
    • (2012) RNA , vol.18 , pp. 1116-1122
    • Gurtan, A.M.1    Lu, V.2    Bhutkar, A.3    Sharp, P.A.4
  • 66
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
    • Forman, J.J., Legesse-Miller, A. and Coller, H.A. (2008) A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc. Natl. Acad. Sci. U.S.A., 105, 14879-14884.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 67
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3- UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr, C. and Bartel, D.P. (2009) Widespread shortening of 3 UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell, 138, 673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 72
    • 70349577785 scopus 로고    scopus 로고
    • Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling
    • Paroo, Z., Ye, X., Chen, S. and Liu, Q. (2009) Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell, 139, 112-122.
    • (2009) Cell , vol.139 , pp. 112-122
    • Paroo, Z.1    Ye, X.2    Chen, S.3    Liu, Q.4
  • 74
    • 84871240981 scopus 로고    scopus 로고
    • Regulation of human Dicer by the resident ER membrane protein CLIMP-63
    • Pepin, G., Perron, M.P. and Provost, P. (2012) Regulation of human Dicer by the resident ER membrane protein CLIMP-63. Nucleic Acids Res., 40, 11603-11617.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 11603-11617
    • Pepin, G.1    Perron, M.P.2    Provost, P.3
  • 76
    • 27144550559 scopus 로고    scopus 로고
    • TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
    • Haase, A.D., Jaskiewicz, L., Zhang, H., Laine, S., Sack, R., Gatignol, A. and Filipowicz, W. (2005) TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep., 6, 961-967.
    • (2005) EMBO Rep. , vol.6 , pp. 961-967
    • Haase, A.D.1    Jaskiewicz, L.2    Zhang, H.3    Laine, S.4    Sack, R.5    Gatignol, A.6    Filipowicz, W.7
  • 77
    • 84880411222 scopus 로고    scopus 로고
    • Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing
    • Lee, H.Y., Zhou, K., Smith, A.M., Noland, C.L. and Doudna, J.A. (2013) Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing. Nucleic Acids Res., 41, 6568-6576.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 6568-6576
    • Lee, H.Y.1    Zhou, K.2    Smith, A.M.3    Noland, C.L.4    Doudna, J.A.5
  • 78
    • 84877059043 scopus 로고    scopus 로고
    • Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA
    • Takahashi, T., Miyakawa, T., Zenno, S., Nishi, K., Tanokura, M. and Ui-Tei, K. (2013) Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA. PLoS One, 8, e63434.
    • (2013) PLoS One , vol.8 , pp. e63434
    • Takahashi, T.1    Miyakawa, T.2    Zenno, S.3    Nishi, K.4    Tanokura, M.5    Ui-Tei, K.6
  • 79
    • 84868106469 scopus 로고    scopus 로고
    • Dicer partner proteins tune the length of mature miRNAs in flies and mammals
    • Fukunaga, R., Han, B.W., Hung, J.H., Xu, J., Weng, Z. and Zamore, P.D. (2012) Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell, 151, 533-546.
    • (2012) Cell , vol.151 , pp. 533-546
    • Fukunaga, R.1    Han, B.W.2    Hung, J.H.3    Xu, J.4    Weng, Z.5    Zamore, P.D.6
  • 81
    • 84867678226 scopus 로고    scopus 로고
    • TRBP alters human precursor microRNA processing in vitro
    • Lee, H.Y. and Doudna, J.A. (2012) TRBP alters human precursor microRNA processing in vitro. RNA, 18, 2012-2019.
    • (2012) RNA , vol.18 , pp. 2012-2019
    • Lee, H.Y.1    Doudna, J.A.2
  • 82
    • 34547115237 scopus 로고    scopus 로고
    • Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA
    • Kok, K.H., Ng, M.H., Ching, Y.P. and Jin, D.Y. (2007) Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. J. Biol. Chem., 282, 17649-17657.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17649-17657
    • Kok, K.H.1    Ng, M.H.2    Ching, Y.P.3    Jin, D.Y.4
  • 83
    • 82755170606 scopus 로고    scopus 로고
    • The role of Dicer protein partners in the processing of microRNA precursors
    • Koscianska, E., Starega-Roslan, J. and Krzyzosiak, W.J. (2011) The role of Dicer protein partners in the processing of microRNA precursors. PLoS One, 6, e28548.
    • (2011) PLoS One , vol.6 , pp. e28548
    • Koscianska, E.1    Starega-Roslan, J.2    Krzyzosiak, W.J.3
  • 86
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • Hutvagner, G. and Zamore, P.D. (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science, 297, 2056-2060.
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvagner, G.1    Zamore, P.D.2
  • 87
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • Gregory, R.I., Chendrimada, T.P., Cooch, N. and Shiekhattar, R. (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell, 123, 631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 88
    • 22144489833 scopus 로고    scopus 로고
    • RNAi: The nuts and bolts of the RISC machine
    • Filipowicz, W. (2005) RNAi: The nuts and bolts of the RISC machine. Cell, 122, 17-20.
    • (2005) Cell , vol.122 , pp. 17-20
    • Filipowicz, W.1
  • 89
    • 67650519133 scopus 로고    scopus 로고
    • The RNA-induced silencing complex: A versatile gene-silencing machine
    • Pratt, A.J. and MacRae, I.J. (2009) The RNA-induced silencing complex: A versatile gene-silencing machine. J. Biol. Chem., 284, 17897-17901.
    • (2009) J. Biol. Chem. , vol.284 , pp. 17897-17901
    • Pratt, A.J.1    Macrae, I.J.2
  • 90
    • 29144431656 scopus 로고    scopus 로고
    • A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
    • Maniataki, E. and Mourelatos, Z. (2005) A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev., 19, 2979-2990.
    • (2005) Genes Dev. , vol.19 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 91
    • 79959872313 scopus 로고    scopus 로고
    • SiRNA repositioning for guide strand selection by human Dicer complexes
    • Noland, C.L., Ma, E. and Doudna, J.A. (2011) siRNA repositioning for guide strand selection by human Dicer complexes. Mol. Cell, 43, 110-121.
    • (2011) Mol. Cell , vol.43 , pp. 110-121
    • Noland, C.L.1    Ma, E.2    Doudna, J.A.3
  • 93
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • Martinez, J., Patkaniowska, A., Urlaub, H., Luhrmann, R. and Tuschl, T. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell, 110, 563-574.
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 94
    • 56649122127 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells
    • Ohrt, T., Mutze, J., Staroske, W., Weinmann, L., Hock, J., Crell, K., Meister, G. and Schwille, P. (2008) Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells. Nucleic Acids Res., 36, 6439-6449.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 6439-6449
    • Ohrt, T.1    Mutze, J.2    Staroske, W.3    Weinmann, L.4    Hock, J.5    Crell, K.6    Meister, G.7    Schwille, P.8
  • 95
    • 84907332153 scopus 로고    scopus 로고
    • The microRNA biology of the mammalian nucleus
    • Roberts, T.C. (2014) The microRNA biology of the mammalian nucleus. Mol. Ther. Nucleic Acids, 3, e188.
    • (2014) Mol. Ther. Nucleic Acids , vol.3 , pp. e188
    • Roberts, T.C.1
  • 97
    • 34547629436 scopus 로고    scopus 로고
    • RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex
    • Kawahara, Y., Zinshteyn, B., Chendrimada, T.P., Shiekhattar, R. and Nishikura, K. (2007) RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex. EMBO Rep., 8, 763-769.
    • (2007) EMBO Rep. , vol.8 , pp. 763-769
    • Kawahara, Y.1    Zinshteyn, B.2    Chendrimada, T.P.3    Shiekhattar, R.4    Nishikura, K.5
  • 101
    • 1642487115 scopus 로고    scopus 로고
    • Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer
    • Tahbaz, N., Kolb, F.A., Zhang, H., Jaronczyk, K., Filipowicz, W. and Hobman, T.C. (2004) Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer. EMBO Rep., 5, 189-194.
    • (2004) EMBO Rep. , vol.5 , pp. 189-194
    • Tahbaz, N.1    Kolb, F.A.2    Zhang, H.3    Jaronczyk, K.4    Filipowicz, W.5    Hobman, T.C.6
  • 102
    • 77957859055 scopus 로고    scopus 로고
    • Dicer is associated with ribosomal DNA chromatin in mammalian cells
    • Sinkkonen, L., Hugenschmidt, T., Filipowicz, W. and Svoboda, P. (2010) Dicer is associated with ribosomal DNA chromatin in mammalian cells. PLoS One, 5, e12175.
    • (2010) PLoS One , vol.5 , pp. e12175
    • Sinkkonen, L.1    Hugenschmidt, T.2    Filipowicz, W.3    Svoboda, P.4
  • 103
    • 33845866637 scopus 로고    scopus 로고
    • H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability
    • Peng, J.C. and Karpen, G.H. (2007) H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat. Cell. Biol., 9, 25-35.
    • (2007) Nat. Cell. Biol. , vol.9 , pp. 25-35
    • Peng, J.C.1    Karpen, G.H.2
  • 104
    • 23044498502 scopus 로고    scopus 로고
    • Comprehensive analysis of heterochromatin-and RNAi-mediated epigenetic control of the fission yeast genome
    • Cam, H.P., Sugiyama, T., Chen, E.S., Chen, X., FitzGerald, P.C. and Grewal, S.I. (2005) Comprehensive analysis of heterochromatin-and RNAi-mediated epigenetic control of the fission yeast genome. Nat. Genet., 37, 809-819.
    • (2005) Nat. Genet. , vol.37 , pp. 809-819
    • Cam, H.P.1    Sugiyama, T.2    Chen, E.S.3    Chen, X.4    Fitzgerald, P.C.5    Grewal, S.I.6
  • 105
    • 84869091742 scopus 로고    scopus 로고
    • Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells
    • Gullerova, M. and Proudfoot, N.J. (2012) Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells. Nat. Struct. Mol. Biol., 19, 1193-1201.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 1193-1201
    • Gullerova, M.1    Proudfoot, N.J.2
  • 109
    • 10644221797 scopus 로고    scopus 로고
    • RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing
    • Noma, K., Sugiyama, T., Cam, H., Verdel, A., Zofall, M., Jia, S., Moazed, D. and Grewal, S.I. (2004) RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing. Nat. Genet., 36, 1174-1180.
    • (2004) Nat. Genet. , vol.36 , pp. 1174-1180
    • Noma, K.1    Sugiyama, T.2    Cam, H.3    Verdel, A.4    Zofall, M.5    Jia, S.6    Moazed, D.7    Grewal, S.I.8
  • 111
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • Volpe, T.A., Kidner, C., Hall, I.M., Teng, G., Grewal, S.I. and Martienssen, R.A. (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science, 297, 1833-1837.
    • (2002) Science , vol.297 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.5    Martienssen, R.A.6
  • 113
    • 27144544472 scopus 로고    scopus 로고
    • Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster
    • Haussecker, D. and Proudfoot, N.J. (2005) Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster. Mol. Cell. Biol., 25, 9724-9733.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 9724-9733
    • Haussecker, D.1    Proudfoot, N.J.2
  • 116
    • 0033180615 scopus 로고    scopus 로고
    • Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer
    • Cramer, P., Caceres, J.F., Cazalla, D., Kadener, S., Muro, A.F., Baralle, F.E. and Kornblihtt, A.R. (1999) Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer. Mol. Cell, 4, 251-258.
    • (1999) Mol. Cell , vol.4 , pp. 251-258
    • Cramer, P.1    Caceres, J.F.2    Cazalla, D.3    Kadener, S.4    Muro, A.F.5    Baralle, F.E.6    Kornblihtt, A.R.7
  • 120
  • 124
    • 41049095100 scopus 로고    scopus 로고
    • HCV core protein interacts with Dicer to antagonize RNA silencing
    • Chen, W., Zhang, Z., Chen, J., Zhang, J., Wu, Y., Huang, Y., Cai, X. and Huang, A. (2008) HCV core protein interacts with Dicer to antagonize RNA silencing. Virus Res., 133, 250-258.
    • (2008) Virus Res. , vol.133 , pp. 250-258
    • Chen, W.1    Zhang, Z.2    Chen, J.3    Zhang, J.4    Wu, Y.5    Huang, Y.6    Cai, X.7    Huang, A.8
  • 125
    • 33644851434 scopus 로고    scopus 로고
    • Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response
    • Wang, Y., Kato, N., Jazag, A., Dharel, N., Otsuka, M., Taniguchi, H., Kawabe, T. and Omata, M. (2006) Hepatitis C virus core protein is a potent inhibitor of RNA silencing-based antiviral response. Gastroenterology, 130, 883-892.
    • (2006) Gastroenterology , vol.130 , pp. 883-892
    • Wang, Y.1    Kato, N.2    Jazag, A.3    Dharel, N.4    Otsuka, M.5    Taniguchi, H.6    Kawabe, T.7    Omata, M.8
  • 126
    • 33846702404 scopus 로고    scopus 로고
    • HIV-1 Tat interaction with Dicer: Requirement for RNA
    • Bennasser, Y. and Jeang, K.T. (2006) HIV-1 Tat interaction with Dicer: Requirement for RNA. Retrovirology, 3, 95.
    • (2006) Retrovirology , vol.3 , pp. 95
    • Bennasser, Y.1    Jeang, K.T.2
  • 127
    • 33748775175 scopus 로고    scopus 로고
    • HIV-1 TAR RNA subverts RNA interference in transfected cells through sequestration of TAR RNA-binding protein
    • Bennasser, Y., Yeung, M.L. and Jeang, K.T. (2006) HIV-1 TAR RNA subverts RNA interference in transfected cells through sequestration of TAR RNA-binding protein, TRBP. J. Biol. Chem., 281, 27674-27678.
    • (2006) TRBP. J. Biol. Chem. , vol.281 , pp. 27674-27678
    • Bennasser, Y.1    Yeung, M.L.2    Jeang, K.T.3
  • 128
    • 84882814047 scopus 로고    scopus 로고
    • The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection
    • Casey Klockow, L., Sharifi, H.J., Wen, X., Flagg, M., Furuya, A.K., Nekorchuk, M. and De Noronha, C.M. (2013) The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection. Virology, 444, 191-202.
    • (2013) Virology , vol.444 , pp. 191-202
    • Casey Klockow, L.1    Sharifi, H.J.2    Wen, X.3    Flagg, M.4    Furuya, A.K.5    Nekorchuk, M.6    De Noronha, C.M.7
  • 130
    • 45349107435 scopus 로고    scopus 로고
    • Stimuli-dependent cleavage of Dicer during apoptosis
    • Matskevich, A.A. and Moelling, K. (2008) Stimuli-dependent cleavage of Dicer during apoptosis. Biochem. J., 412, 527-534.
    • (2008) Biochem. J. , vol.412 , pp. 527-534
    • Matskevich, A.A.1    Moelling, K.2
  • 131
    • 77951195672 scopus 로고    scopus 로고
    • Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease
    • Nakagawa, A., Shi, Y., Kage-Nakadai, E., Mitani, S. and Xue, D. (2010) Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease. Science, 328, 327-334.
    • (2010) Science , vol.328 , pp. 327-334
    • Nakagawa, A.1    Shi, Y.2    Kage-Nakadai, E.3    Mitani, S.4    Xue, D.5
  • 134
    • 67349200238 scopus 로고    scopus 로고
    • Abrogation of DNA vector-based RNAi during apoptosis in mammalian cells due to caspase-mediated cleavage and inactivation of Dicer-1
    • Ghodgaonkar, M.M., Shah, R.G., Kandan-Kulangara, F., Affar, E.B., Qi, H.H., Wiemer, E. and Shah, G.M. (2009) Abrogation of DNA vector-based RNAi during apoptosis in mammalian cells due to caspase-mediated cleavage and inactivation of Dicer-1. Cell Death Differ., 16, 858-868.
    • (2009) Cell Death Differ. , vol.16 , pp. 858-868
    • Ghodgaonkar, M.M.1    Shah, R.G.2    Kandan-Kulangara, F.3    Affar, E.B.4    Qi, H.H.5    Wiemer, E.6    Shah, G.M.7
  • 136
    • 77049099101 scopus 로고    scopus 로고
    • Lin28: A microRNA regulator with a macro role
    • Viswanathan, S.R. and Daley, G.Q. (2010) Lin28: A microRNA regulator with a macro role. Cell, 140, 445-449.
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 137
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan, S.R., Daley, G.Q. and Gregory, R.I. (2008) Selective blockade of microRNA processing by Lin28. Science, 320, 97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 138
    • 52049124806 scopus 로고    scopus 로고
    • Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
    • Piskounova, E., Viswanathan, S.R., Janas, M., LaPierre, R.J., Daley, G.Q., Sliz, P. and Gregory, R.I. (2008) Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J. Biol. Chem., 283, 21310-21314.
    • (2008) J. Biol. Chem. , vol.283 , pp. 21310-21314
    • Piskounova, E.1    Viswanathan, S.R.2    Janas, M.3    Lapierre, R.J.4    Daley, G.Q.5    Sliz, P.6    Gregory, R.I.7
  • 139
    • 68749102148 scopus 로고    scopus 로고
    • TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
    • Heo, I., Joo, C., Kim, Y.K., Ha, M., Yoon, M.J., Cho, J., Yeom, K.H., Han, J. and Kim, V.N. (2009) TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell, 138, 696-708.
    • (2009) Cell , vol.138 , pp. 696-708
    • Heo, I.1    Joo, C.2    Kim, Y.K.3    Ha, M.4    Yoon, M.J.5    Cho, J.6    Yeom, K.H.7    Han, J.8    Kim, V.N.9
  • 140
    • 80053208703 scopus 로고    scopus 로고
    • Deep sequencing of microRNA precursors reveals extensive 3- end modification
    • Newman, M.A., Mani, V. and Hammond, S.M. (2011) Deep sequencing of microRNA precursors reveals extensive 3' end modification. RNA, 17, 1795-1803.
    • (2011) RNA , vol.17 , pp. 1795-1803
    • Newman, M.A.1    Mani, V.2    Hammond, S.M.3
  • 141
    • 84898976714 scopus 로고    scopus 로고
    • Stepwise assembly of multiple Lin28 proteins on the terminal loop of let-7 miRNA precursors
    • Desjardins, A., Bouvette, J. and Legault, P. (2014) Stepwise assembly of multiple Lin28 proteins on the terminal loop of let-7 miRNA precursors. Nucleic Acids Res., 42, 4615-4628.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 4615-4628
    • Desjardins, A.1    Bouvette, J.2    Legault, P.3
  • 142
    • 84893097200 scopus 로고    scopus 로고
    • The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7
    • Chaulk, S.G., Lattanzi, V.J., Hiemer, S.E., Fahlman, R.P. and Varelas, X. (2013) The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7. J. Biol. Chem., 289, 1886-1891.
    • (2013) J. Biol. Chem. , vol.289 , pp. 1886-1891
    • Chaulk, S.G.1    Lattanzi, V.J.2    Hiemer, S.E.3    Fahlman, R.P.4    Varelas, X.5
  • 143
    • 77957883342 scopus 로고    scopus 로고
    • The hippo signaling pathway in development and cancer
    • Pan, D. (2010) The hippo signaling pathway in development and cancer. Dev. Cell, 19, 491-505.
    • (2010) Dev. Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 144
    • 79960997489 scopus 로고    scopus 로고
    • The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
    • Zhao, B., Tumaneng, K. and Guan, K.L. (2011) The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat. Cell Biol., 13, 877-883.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 877-883
    • Zhao, B.1    Tumaneng, K.2    Guan, K.L.3
  • 147
    • 77955425756 scopus 로고    scopus 로고
    • Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
    • Michlewski, G. and Caceres, J.F. (2010) Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat. Struct. Mol. Biol., 17, 1011-1018.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 1011-1018
    • Michlewski, G.1    Caceres, J.F.2
  • 148
    • 2942612333 scopus 로고    scopus 로고
    • A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
    • Gherzi, R., Lee, K.Y., Briata, P., Wegmuller, D., Moroni, C., Karin, M. and Chen, C.Y. (2004) A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol. Cell, 14, 571-583.
    • (2004) Mol. Cell , vol.14 , pp. 571-583
    • Gherzi, R.1    Lee, K.Y.2    Briata, P.3    Wegmuller, D.4    Moroni, C.5    Karin, M.6    Chen, C.Y.7
  • 149
    • 33646590585 scopus 로고    scopus 로고
    • Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay
    • Chou, C.F., Mulky, A., Maitra, S., Lin, W.J., Gherzi, R., Kappes, J. and Chen, C.Y. (2006) Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay. Mol. Cell. Biol., 26, 3695-3706.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 3695-3706
    • Chou, C.F.1    Mulky, A.2    Maitra, S.3    Lin, W.J.4    Gherzi, R.5    Kappes, J.6    Chen, C.Y.7
  • 150
    • 0030969572 scopus 로고    scopus 로고
    • A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
    • Min, H., Turck, C.W., Nikolic, J.M. and Black, D.L. (1997) A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev., 11, 1023-1036.
    • (1997) Genes Dev. , vol.11 , pp. 1023-1036
    • Min, H.1    Turck, C.W.2    Nikolic, J.M.3    Black, D.L.4
  • 151
    • 0037033786 scopus 로고    scopus 로고
    • A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons
    • Gu, W., Pan, F., Zhang, H., Bassell, G.J. and Singer, R.H. (2002) A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J. Cell Biol., 156, 41-51.
    • (2002) J. Cell Biol. , vol.156 , pp. 41-51
    • Gu, W.1    Pan, F.2    Zhang, H.3    Bassell, G.J.4    Singer, R.H.5
  • 154
    • 79951500251 scopus 로고    scopus 로고
    • The ATM kinase induces microRNA biogenesis in the DNA damage response
    • Zhang, X., Wan, G., Berger, F.G., He, X. and Lu, X. (2011) The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol. Cell, 41, 371-383.
    • (2011) Mol. Cell , vol.41 , pp. 371-383
    • Zhang, X.1    Wan, G.2    Berger, F.G.3    He, X.4    Lu, X.5
  • 155
    • 84857772495 scopus 로고    scopus 로고
    • TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
    • Kawahara, Y. and Mieda-Sato, A. (2012) TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proc. Natl. Acad. Sci. U.S.A., 109, 3347-3352.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 3347-3352
    • Kawahara, Y.1    Mieda-Sato, A.2
  • 160
    • 80555127350 scopus 로고    scopus 로고
    • MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation
    • Suzuki, H.I., Arase, M., Matsuyama, H., Choi, Y.L., Ueno, T., Mano, H., Sugimoto, K. and Miyazono, K. (2011) MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol. Cell, 44, 424-436.
    • (2011) Mol. Cell , vol.44 , pp. 424-436
    • Suzuki, H.I.1    Arase, M.2    Matsuyama, H.3    Choi, Y.L.4    Ueno, T.5    Mano, H.6    Sugimoto, K.7    Miyazono, K.8
  • 165
    • 84905308904 scopus 로고    scopus 로고
    • A new short oligonucleotide-based strategy for the precursor-specific regulation of microRNA processing by dicer
    • Kurzynska-Kokorniak, A., Koralewska, N., Tyczewska, A., Twardowski, T. and Figlerowicz, M. (2013) A new short oligonucleotide-based strategy for the precursor-specific regulation of microRNA processing by dicer. PLoS One, 8, e77703.
    • (2013) PLoS One , vol.8 , pp. e77703
    • Kurzynska-Kokorniak, A.1    Koralewska, N.2    Tyczewska, A.3    Twardowski, T.4    Figlerowicz, M.5
  • 166
    • 84863005508 scopus 로고    scopus 로고
    • Autoregulation of microRNA biogenesis by let-7 and Argonaute
    • Zisoulis, D.G., Kai, Z.S., Chang, R.K. and Pasquinelli, A.E. (2012) Autoregulation of microRNA biogenesis by let-7 and Argonaute. Nature, 486, 541-544.
    • (2012) Nature , vol.486 , pp. 541-544
    • Zisoulis, D.G.1    Kai, Z.S.2    Chang, R.K.3    Pasquinelli, A.E.4
  • 170
    • 84884498747 scopus 로고    scopus 로고
    • Identification of stable, high copy number, medium-sized RNA degradation intermediates that accumulate in plants under non-stress conditions
    • Nowacka, M., Strozycki, P.M., Jackowiak, P., Hojka-Osinska, A., Szymanski, M. and Figlerowicz, M. (2013) Identification of stable, high copy number, medium-sized RNA degradation intermediates that accumulate in plants under non-stress conditions. Plant Mol. Biol., 83, 191-204.
    • (2013) Plant Mol. Biol. , vol.83 , pp. 191-204
    • Nowacka, M.1    Strozycki, P.M.2    Jackowiak, P.3    Hojka-Osinska, A.4    Szymanski, M.5    Figlerowicz, M.6
  • 171
    • 38649135702 scopus 로고    scopus 로고
    • Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes
    • Kagami, M., Sekita, Y., Nishimura, G., Irie, M., Kato, F., Okada, M., Yamamori, S., Kishimoto, H., Nakayama, M., Tanaka, Y. et al. (2008) Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. Nat. Genet., 40, 237-242.
    • (2008) Nat. Genet. , vol.40 , pp. 237-242
    • Kagami, M.1    Sekita, Y.2    Nishimura, G.3    Irie, M.4    Kato, F.5    Okada, M.6    Yamamori, S.7    Kishimoto, H.8    Nakayama, M.9    Tanaka, Y.10
  • 174
    • 84872958116 scopus 로고    scopus 로고
    • Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage
    • Anglesio, M.S., Wang, Y., Yang, W., Senz, J., Wan, A., Heravi-Moussavi, A., Salamanca, C., Maines-Bandiera, S., Huntsman, D.G. and Morin, G.B. (2013) Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage. J. Pathol., 229, 400-409.
    • (2013) J. Pathol. , vol.229 , pp. 400-409
    • Anglesio, M.S.1    Wang, Y.2    Yang, W.3    Senz, J.4    Wan, A.5    Heravi-Moussavi, A.6    Salamanca, C.7    Maines-Bandiera, S.8    Huntsman, D.G.9    Morin, G.B.10
  • 180
    • 0347694725 scopus 로고    scopus 로고
    • Defective RNA-mediated c-myc gene silencing pathway in Burkitt's lymphoma
    • Kaul, D. and Sikand, K. (2004) Defective RNA-mediated c-myc gene silencing pathway in Burkitt's lymphoma. Biochem. Biophys. Res. Commun., 313, 552-554.
    • (2004) Biochem. Biophys. Res. Commun. , vol.313 , pp. 552-554
    • Kaul, D.1    Sikand, K.2
  • 181
    • 84899474027 scopus 로고    scopus 로고
    • Expanding the phenotype of mutations in DICER1: Mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome
    • Klein, S., Lee, H., Ghahremani, S., Kempert, P., Ischander, M., Teitell, M.A., Nelson, S.F. and Martinez-Agosto, J.A. (2014) Expanding the phenotype of mutations in DICER1: Mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome. J. Med. Genet., 51, 294-302.
    • (2014) J. Med. Genet. , vol.51 , pp. 294-302
    • Klein, S.1    Lee, H.2    Ghahremani, S.3    Kempert, P.4    Ischander, M.5    Teitell, M.A.6    Nelson, S.F.7    Martinez-Agosto, J.A.8
  • 184
    • 79953699619 scopus 로고    scopus 로고
    • DICER1 syndrome: Clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome
    • Slade, I., Bacchelli, C., Davies, H., Murray, A., Abbaszadeh, F., Hanks, S., Barfoot, R., Burke, A., Chisholm, J., Hewitt, M. et al. (2011) DICER1 syndrome: Clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome. J. Med. Genet., 48, 273-278.
    • (2011) J. Med. Genet. , vol.48 , pp. 273-278
    • Slade, I.1    Bacchelli, C.2    Davies, H.3    Murray, A.4    Abbaszadeh, F.5    Hanks, S.6    Barfoot, R.7    Burke, A.8    Chisholm, J.9    Hewitt, M.10
  • 185
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson, A.G. Jr (1971) Mutation and cancer: Statistical study of retinoblastoma. Proc. Natl. Acad. Sci. U.S.A., 68, 820-823.
    • (1971) Proc. Natl. Acad. Sci. U.S.A. , vol.68 , pp. 820-823
    • Knudson, A.G.1
  • 191
    • 84892553849 scopus 로고    scopus 로고
    • DICER1 mutations in an adolescent with cervical embryonal rhabdomyosarcoma (cERMS)
    • Tomiak, E., De Kock, L., Grynspan, D., Ramphal, R. and Foulkes, W.D. (2014) DICER1 mutations in an adolescent with cervical embryonal rhabdomyosarcoma (cERMS). Pediatr. Blood Cancer, 61, 568-569.
    • (2014) Pediatr. Blood Cancer , vol.61 , pp. 568-569
    • Tomiak, E.1    De Kock, L.2    Grynspan, D.3    Ramphal, R.4    Foulkes, W.D.5
  • 193
    • 36649025655 scopus 로고    scopus 로고
    • OncomiRs: The discovery and progress of microRNAs in cancers
    • Cho, W.C. (2007) OncomiRs: The discovery and progress of microRNAs in cancers. Mol. Cancer, 6, 60.
    • (2007) Mol. Cancer , vol.6 , pp. 60
    • Cho, W.C.1
  • 194
    • 77957197569 scopus 로고    scopus 로고
    • Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers
    • Krutovskikh, V.A. and Herceg, Z. (2010) Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers. Bioessays, 32, 894-904.
    • (2010) Bioessays , vol.32 , pp. 894-904
    • Krutovskikh, V.A.1    Herceg, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.