메뉴 건너뛰기




Volumn 9, Issue 8, 2009, Pages 927-937

Human- and virus-encoded microRNAs as potential targets of antiviral therapy

Author keywords

AntagomiR; Antiviral therapy; Artificial miRNA; Host virus interaction; MicroRNA; MiRNA mimetic; Target protector

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ANTIVIRUS AGENT; BETA INTERFERON; COMPLEMENTARY RNA; DICER; EXPORTIN 5; LIPOSOME; LOCKED NUCLEIC ACID; MICRORNA; PEPTIDE NUCLEIC ACID; PHOSPHOROTHIOIC ACID; POLYETHYLENEIMINE; RIBONUCLEASE; RNA INDUCED SILENCING COMPLEX; RNA POLYMERASE II; SMALL INTERFERING RNA; VIRUS RNA;

EID: 70349085411     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955709788681573     Document Type: Article
Times cited : (22)

References (83)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A.; Xu, S.; Montgomery, M.K.; Kostas, S.A.; Driver, S.E.; Mello, C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391, 806-11.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 2
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon, G.J. RNA interference. Nature, 2002, 418, 244-51.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 3
    • 33746636025 scopus 로고    scopus 로고
    • Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes
    • Kim, V.N. Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes. Genes Dev., 2006, 20, 1993-7.
    • (2006) Genes Dev , vol.20 , pp. 1993-1997
    • Kim, V.N.1
  • 4
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M.; Rauhut, R.; Lendeckel, W.; Tuschl, T. Identification of novel genes coding for small expressed RNAs. Science, 2001, 294, 853-8.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 5
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N.C.; Lim, L.P.; Weinstein, E.G.; Bartel, D.P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science, 2001, 294, 858-62.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 6
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • Kim, V.N. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol., 2005, 6, 376-85.
    • (2005) Nat. Rev. Mol. Cell Biol , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 7
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B.P.; Burge, C.B.; Bartel, D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 2005, 120, 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 8
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G.A.; Croce, C.M. MicroRNA signatures in human cancers. Nat. Rev. Cancer, 2006, 6, 857-66.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 9
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher, A.; Slack, F.J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer, 2006, 6, 259-69.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 10
    • 1842534581 scopus 로고    scopus 로고
    • RNA silencing: A conserved antiviral immunity of plants and animals
    • Ding, S.W.; Li, H.; Lu, R.; Li, F.; Li, W.X. RNA silencing: a conserved antiviral immunity of plants and animals. Virus Res., 2004, 102, 109-15.
    • (2004) Virus Res , vol.102 , pp. 109-115
    • Ding, S.W.1    Li, H.2    Lu, R.3    Li, F.4    Li, W.X.5
  • 11
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • Jopling, C.L.; Yi, M.; Lancaster, A.M.; Lemon, S.M.; Sarnow, P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science, 2005, 309, 1577-81.
    • (2005) Science , vol.309 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 14
    • 33645803814 scopus 로고    scopus 로고
    • RNA interference: Its use as antiviral therapy
    • Haasnoot, J.; Berkhout, B. RNA interference: its use as antiviral therapy. Handb. Exp. Pharmacol., 2006, 117-50.
    • (2006) Handb. Exp. Pharmacol , pp. 117-150
    • Haasnoot, J.1    Berkhout, B.2
  • 15
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond, S.M.; Bernstein, E.; Beach, D.; Hannon, G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 2000, 404, 293-6.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 18
    • 34247364093 scopus 로고    scopus 로고
    • Mechanisms of microRNA-mediated gene regulation in animal cells
    • Nilsen, T.W. Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet., 2007, 23, 243-9.
    • (2007) Trends Genet , vol.23 , pp. 243-249
    • Nilsen, T.W.1
  • 19
    • 33645119514 scopus 로고    scopus 로고
    • MicroRNAs direct rapid deadenylation of mRNA
    • Wu, L.; Fan, J.; Belasco, J.G. MicroRNAs direct rapid deadenylation of mRNA. Proc. Natl. Acad. Sci. USA, 2006, 103, 4034-9.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4034-4039
    • Wu, L.1    Fan, J.2    Belasco, J.G.3
  • 20
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • Liu, J.; Valencia-Sanchez, M.A.; Hannon, G.J.; Parker, R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol., 2005, 7, 719-23.
    • (2005) Nat. Cell Biol , vol.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 21
    • 20444427566 scopus 로고    scopus 로고
    • Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
    • Sen, G.L.; Blau, H.M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat. Cell Biol., 2005, 7, 633-6.
    • (2005) Nat. Cell Biol , vol.7 , pp. 633-636
    • Sen, G.L.1    Blau, H.M.2
  • 24
    • 33746055678 scopus 로고    scopus 로고
    • mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
    • Behm-Ansmant, I.; Rehwinkel, J.; Doerks, T.; Stark, A.; Bork, P.; Izaurralde, E. mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev., 2006, 20, 1885-98.
    • (2006) Genes Dev , vol.20 , pp. 1885-1898
    • Behm-Ansmant, I.1    Rehwinkel, J.2    Doerks, T.3    Stark, A.4    Bork, P.5    Izaurralde, E.6
  • 29
    • 31144451840 scopus 로고    scopus 로고
    • Adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production
    • Aparicio, O.; Razquin, N.; Zaratiegui, M.; Narvaiza, I.; Fortes, P. Adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production. J. Virol., 2006, 80, 1376-84.
    • (2006) J. Virol , vol.80 , pp. 1376-1384
    • Aparicio, O.1    Razquin, N.2    Zaratiegui, M.3    Narvaiza, I.4    Fortes, P.5
  • 30
    • 17244375710 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells
    • Cai, X.; Lu, S.; Zhang, Z.; Gonzalez, C.M.; Damania, B.; Cullen, B.R. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc. Natl. Acad. Sci. USA, 2005, 102, 5570-5.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5570-5575
    • Cai, X.1    Lu, S.2    Zhang, Z.3    Gonzalez, C.M.4    Damania, B.5    Cullen, B.R.6
  • 33
    • 33646168051 scopus 로고    scopus 로고
    • A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses
    • Grundhoff, A.; Sullivan, C.S.; Ganem, D. A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA, 2006, 12, 733-50.
    • (2006) RNA , vol.12 , pp. 733-750
    • Grundhoff, A.1    Sullivan, C.S.2    Ganem, D.3
  • 35
    • 21644438873 scopus 로고    scopus 로고
    • Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus
    • Samols, M.A.; Hu, J.; Skalsky, R.L.; Renne, R. Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus. J. Virol., 2005, 79, 9301-5.
    • (2005) J. Virol , vol.79 , pp. 9301-9305
    • Samols, M.A.1    Hu, J.2    Skalsky, R.L.3    Renne, R.4
  • 37
    • 33749512418 scopus 로고    scopus 로고
    • Pfeffer, S.; Voinnet, O. Viruses, microRNAs and cancer. Oncogene, 2006, 25, 6211-9.
    • Pfeffer, S.; Voinnet, O. Viruses, microRNAs and cancer. Oncogene, 2006, 25, 6211-9.
  • 38
    • 33749056373 scopus 로고    scopus 로고
    • Cloning and detection of HIV-1-encoded microRNA
    • Omoto, S.; Fujii, Y.R. Cloning and detection of HIV-1-encoded microRNA. Methods Mol. Biol., 2006, 342, 255-65.
    • (2006) Methods Mol. Biol , vol.342 , pp. 255-265
    • Omoto, S.1    Fujii, Y.R.2
  • 40
    • 34548304523 scopus 로고    scopus 로고
    • HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR
    • Klase, Z.; Kale, P.; Winograd, R.; Gupta, M.V.; Heydarian, M.; Berro, R.; McCaffrey, T.; Kashanchi, F. HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. BMC Mol. Biol., 2007, 8, 63.
    • (2007) BMC Mol. Biol , vol.8 , pp. 63
    • Klase, Z.1    Kale, P.2    Winograd, R.3    Gupta, M.V.4    Heydarian, M.5    Berro, R.6    McCaffrey, T.7    Kashanchi, F.8
  • 43
    • 14344260087 scopus 로고    scopus 로고
    • HIV-1 encoded candidate micro-RNAs and their cellular targets
    • Bennasser, Y.; Le, S.Y.; Yeung, M.L.; Jeang, K.T. HIV-1 encoded candidate micro-RNAs and their cellular targets. Retrovirology, 2004, 1, 43.
    • (2004) Retrovirology , vol.1 , pp. 43
    • Bennasser, Y.1    Le, S.Y.2    Yeung, M.L.3    Jeang, K.T.4
  • 44
    • 33344465450 scopus 로고    scopus 로고
    • Sequence-specific interference by small RNAs derived from adenovirus VAI RNA
    • Sano, M.; Kato, Y.; Taira, K. Sequence-specific interference by small RNAs derived from adenovirus VAI RNA. FEBS Lett., 2006, 580, 1553-64.
    • (2006) FEBS Lett , vol.580 , pp. 1553-1564
    • Sano, M.1    Kato, Y.2    Taira, K.3
  • 45
    • 33745249539 scopus 로고    scopus 로고
    • Viruses and microRNAs
    • Cullen, B.R. Viruses and microRNAs. Nat. Genet., 2006, 38 Suppl, S25-S30.
    • (2006) Nat. Genet , vol.38 , Issue.SUPPL.
    • Cullen, B.R.1
  • 46
    • 20444446357 scopus 로고    scopus 로고
    • SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells
    • Sullivan, C.S.; Grundhoff, A.T.; Tevethia, S.; Pipas, J.M.; Ganem, D. SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature, 2005, 435, 682-6.
    • (2005) Nature , vol.435 , pp. 682-686
    • Sullivan, C.S.1    Grundhoff, A.T.2    Tevethia, S.3    Pipas, J.M.4    Ganem, D.5
  • 47
    • 44449105456 scopus 로고    scopus 로고
    • Suppression of immediate-early viral gene expression by herpesviruscoded microRNAs: Implications for latency
    • Murphy, E.; Vanicek, J.; Robins, H.; Shenk, T.; Levine, A.J. Suppression of immediate-early viral gene expression by herpesviruscoded microRNAs: implications for latency. Proc. Natl. Acad. Sci. U. S. A., 2008, 105, 5453-8.
    • (2008) Proc. Natl. Acad. Sci. U. S. A , vol.105 , pp. 5453-5458
    • Murphy, E.1    Vanicek, J.2    Robins, H.3    Shenk, T.4    Levine, A.J.5
  • 48
    • 49649119633 scopus 로고    scopus 로고
    • MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs
    • Umbach, J.L.; Kramer, M.F.; Jurak, I.; Karnowski, H.W.; Coen, D.M.; Cullen, B.R. MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature, 2008, 454, 780-3.
    • (2008) Nature , vol.454 , pp. 780-783
    • Umbach, J.L.1    Kramer, M.F.2    Jurak, I.3    Karnowski, H.W.4    Coen, D.M.5    Cullen, B.R.6
  • 49
    • 33645958296 scopus 로고    scopus 로고
    • Virus-encoded microRNAs: Novel regulators of gene expression
    • Nair, V.; Zavolan, M. Virus-encoded microRNAs: novel regulators of gene expression. Trends Microbiol., 2006, 14, 169-75.
    • (2006) Trends Microbiol , vol.14 , pp. 169-175
    • Nair, V.1    Zavolan, M.2
  • 50
    • 18044390846 scopus 로고    scopus 로고
    • HIV may produce inhibitory microRNAs (miRNAs) that block production of CD28, CD4 and some interleukins
    • Couturier, J.P.; Root-Bernstein, R.S. HIV may produce inhibitory microRNAs (miRNAs) that block production of CD28, CD4 and some interleukins. J. Theor. Biol., 2005, 235, 169-84.
    • (2005) J. Theor. Biol , vol.235 , pp. 169-184
    • Couturier, J.P.1    Root-Bernstein, R.S.2
  • 51
    • 33746018653 scopus 로고    scopus 로고
    • Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript
    • Gupta, A.; Gartner, J.J.; Sethupathy, P.; Hatzigeorgiou, A.G.; Fraser, N.W. Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature, 2006, 442, 82-5.
    • (2006) Nature , vol.442 , pp. 82-85
    • Gupta, A.1    Gartner, J.J.2    Sethupathy, P.3    Hatzigeorgiou, A.G.4    Fraser, N.W.5
  • 52
    • 38749102371 scopus 로고    scopus 로고
    • Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript
    • Gartner, J.J.; Sethupathy, P.; Hatzigeorgiou, A.G.; Fraser, N.W. Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature, 2008, 451, 600.
    • (2008) Nature , vol.451 , pp. 600
    • Gartner, J.J.1    Sethupathy, P.2    Hatzigeorgiou, A.G.3    Fraser, N.W.4
  • 57
    • 38849209304 scopus 로고    scopus 로고
    • Not miR-ly small RNAs: Big potential for microRNAs in therapy
    • Love, T.M.; Moffett, H.F.; Novina, C.D. Not miR-ly small RNAs: big potential for microRNAs in therapy. J. Allergy Clin. Immunol., 2008, 121, 309-19.
    • (2008) J. Allergy Clin. Immunol , vol.121 , pp. 309-319
    • Love, T.M.1    Moffett, H.F.2    Novina, C.D.3
  • 58
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng, Y.; Wagner, E.J.; Cullen, B.R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell, 2002, 9, 1327-33.
    • (2002) Mol. Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 59
    • 33751264968 scopus 로고    scopus 로고
    • Synthetic microRNA designed to target gliomaassociated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells
    • Tsuda, N.; Ishiyama, S.; Li, Y.; Ioannides, C.G.; Abbruzzese, J.L.; Chang, D.Z. Synthetic microRNA designed to target gliomaassociated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. Clin. Cancer Res., 2006, 12, 6557-64.
    • (2006) Clin. Cancer Res , vol.12 , pp. 6557-6564
    • Tsuda, N.1    Ishiyama, S.2    Li, Y.3    Ioannides, C.G.4    Abbruzzese, J.L.5    Chang, D.Z.6
  • 61
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee, Y.S.; Kim, H.K.; Chung, S.; Kim, K.S.; Dutta, A. Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J. Biol. Chem., 2005, 280, 16635-41.
    • (2005) J. Biol. Chem , vol.280 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 63
    • 33645075443 scopus 로고    scopus 로고
    • Esau, C.; Davis, S.; Murray, S.F.; Yu, X.X.; Pandey, S.K.; Pear, M.; Watts, L.; Booten, S.L.; Graham, M.; McKay, R.; Subramaniam, A.; Propp, S.; Lollo, B.A.; Freier, S.; Bennett, C.F.; Bhanot, S.; Monia, B.P. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab., 2006, 3, 87-98.
    • Esau, C.; Davis, S.; Murray, S.F.; Yu, X.X.; Pandey, S.K.; Pear, M.; Watts, L.; Booten, S.L.; Graham, M.; McKay, R.; Subramaniam, A.; Propp, S.; Lollo, B.A.; Freier, S.; Bennett, C.F.; Bhanot, S.; Monia, B.P. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab., 2006, 3, 87-98.
  • 64
    • 35348914716 scopus 로고    scopus 로고
    • Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430
    • Choi, W.Y.; Giraldez, A.J.; Schier, A.F. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science, 2007, 318, 271-4.
    • (2007) Science , vol.318 , pp. 271-274
    • Choi, W.Y.1    Giraldez, A.J.2    Schier, A.F.3
  • 65
    • 34249951149 scopus 로고    scopus 로고
    • Artificial microRNA-mediated virus resistance in plants
    • Qu, J.; Ye, J.; Fang, R. Artificial microRNA-mediated virus resistance in plants. J. Virol., 2007, 81, 6690-9.
    • (2007) J. Virol , vol.81 , pp. 6690-6699
    • Qu, J.1    Ye, J.2    Fang, R.3
  • 66
    • 33746581992 scopus 로고    scopus 로고
    • Delivery Systems for the Direct Application of siRNAs to Induce RNA Interference (RNAi)
    • Aigner, A. Delivery Systems for the Direct Application of siRNAs to Induce RNA Interference (RNAi) In Vivo. J. Biomed. Biotechnol., 2006, 2006, 71659.
    • (2006) In Vivo. J. Biomed. Biotechnol , vol.2006 , pp. 71659
    • Aigner, A.1
  • 67
    • 33947537002 scopus 로고    scopus 로고
    • Virus-encoded microRNAs: Future therapeutic targets?
    • Qi, P.; Han, J.X.; Lu, Y.Q.; Wang, C.; Bu, F.F. Virus-encoded microRNAs: future therapeutic targets? Cell. Mol. Immunol., 2006, 3, 411-9.
    • (2006) Cell. Mol. Immunol , vol.3 , pp. 411-419
    • Qi, P.1    Han, J.X.2    Lu, Y.Q.3    Wang, C.4    Bu, F.F.5
  • 68
    • 33646715590 scopus 로고    scopus 로고
    • Improved targeting of miRNA with antisense oligonucleotides
    • Davis, S.; Lollo, B.; Freier, S.; Esau, C. Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Res., 2006, 34, 2294-304.
    • (2006) Nucleic Acids Res , vol.34 , pp. 2294-2304
    • Davis, S.1    Lollo, B.2    Freier, S.3    Esau, C.4
  • 69
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J.A.; Krichevsky, A.M.; Kosik, K.S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 2005, 65, 6029-33.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 70
    • 0345064195 scopus 로고    scopus 로고
    • Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes
    • Boutla, A.; Delidakis, C.; Tabler, M. Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. Nucleic Acids Res., 2003, 31, 4973-80.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4973-4980
    • Boutla, A.1    Delidakis, C.2    Tabler, M.3
  • 71
    • 38649105459 scopus 로고    scopus 로고
    • Fabani, M.M.; Gait, M.J. miR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNApeptide conjugates. RNA, 2008, 14, 336-46.
    • Fabani, M.M.; Gait, M.J. miR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNApeptide conjugates. RNA, 2008, 14, 336-46.
  • 72
    • 33746438424 scopus 로고    scopus 로고
    • Toxicity of cationic lipids and cationic polymers in gene delivery
    • Lv, H.; Zhang, S.; Wang, B.; Cui, S.; Yan, J. Toxicity of cationic lipids and cationic polymers in gene delivery. J. Control. Release, 2006, 114, 100-9.
    • (2006) J. Control. Release , vol.114 , pp. 100-109
    • Lv, H.1    Zhang, S.2    Wang, B.3    Cui, S.4    Yan, J.5
  • 74
    • 9244257843 scopus 로고    scopus 로고
    • Virus-like particles as vaccines and vessels for the delivery of small molecules
    • Garcea, R.L.; Gissmann, L. Virus-like particles as vaccines and vessels for the delivery of small molecules. Curr. Opin. Biotechnol., 2004, 15, 513-7.
    • (2004) Curr. Opin. Biotechnol , vol.15 , pp. 513-517
    • Garcea, R.L.1    Gissmann, L.2
  • 75
    • 33748433244 scopus 로고    scopus 로고
    • Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery
    • Mae, M.; Langel, U. Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery. Curr. Opin. Pharmacol., 2006, 6, 509-14.
    • (2006) Curr. Opin. Pharmacol , vol.6 , pp. 509-514
    • Mae, M.1    Langel, U.2
  • 77
    • 52749083438 scopus 로고    scopus 로고
    • Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells
    • Horwich, M.D.; Zamore, P.D. Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. Nat. Protoc., 2008, 3, 1537-49.
    • (2008) Nat. Protoc , vol.3 , pp. 1537-1549
    • Horwich, M.D.1    Zamore, P.D.2
  • 79
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz, M.; Trono, D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol., 2003, 77, 8957-61.
    • (2003) J. Virol , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 80
    • 24944560377 scopus 로고    scopus 로고
    • A lentiviral microRNA-based system for single-copy polymerase IIregulated RNA interference in mammalian cells
    • Stegmeier, F.; Hu, G.; Rickles, R.J.; Hannon, G.J.; Elledge, S.J. A lentiviral microRNA-based system for single-copy polymerase IIregulated RNA interference in mammalian cells. Proc. Natl. Acad. Sci. U. S. A., 2005, 102, 13212-7.
    • (2005) Proc. Natl. Acad. Sci. U. S. A , vol.102 , pp. 13212-13217
    • Stegmeier, F.1    Hu, G.2    Rickles, R.J.3    Hannon, G.J.4    Elledge, S.J.5
  • 83
    • 39549088290 scopus 로고    scopus 로고
    • A balancing act: Viruses and miRNAs
    • Berkhout, B. A balancing act: viruses and miRNAs. J. Formos. Med. Assoc., 2008, 107, 1-3.
    • (2008) J. Formos. Med. Assoc , vol.107 , pp. 1-3
    • Berkhout, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.