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Volumn 151, Issue 4, 2012, Pages 900-911

The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MICRORNA; SHORT HAIRPIN RNA;

EID: 84869037267     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.09.042     Document Type: Article
Times cited : (239)

References (52)
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 3
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • DOI 10.1126/science.1068999
    • T.R. Brummelkamp, R. Bernards, and R. Agami A system for stable expression of short interfering RNAs in mammalian cells Science 296 2002 550 553 (Pubitemid 34408678)
    • (2002) Science , vol.296 , Issue.5567 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 6
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • R.W. Carthew, and E.J. Sontheimer Origins and mechanisms of miRNAs and siRNAs Cell 136 2009 642 655
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 7
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • DOI 10.1038/nature03868
    • T.P. Chendrimada, R.I. Gregory, E. Kumaraswamy, J. Norman, N. Cooch, K. Nishikura, and R. Shiekhattar TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing Nature 436 2005 740 744 (Pubitemid 41117280)
    • (2005) Nature , vol.436 , Issue.7051 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3    Norman, J.4    Cooch, N.5    Nishikura, K.6    Shiekhattar, R.7
  • 10
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • DOI 10.1038/35078107
    • S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498 (Pubitemid 32494397)
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 11
    • 77953479619 scopus 로고    scopus 로고
    • Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2
    • F. Frank, N. Sonenberg, and B. Nagar Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2 Nature 465 2010 818 822
    • (2010) Nature , vol.465 , pp. 818-822
    • Frank, F.1    Sonenberg, N.2    Nagar, B.3
  • 12
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • R.C. Friedman, K.K. Farh, C.B. Burge, and D.P. Bartel Most mammalian mRNAs are conserved targets of microRNAs Genome Res. 19 2009 92 105
    • (2009) Genome Res. , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 13
    • 33745299723 scopus 로고    scopus 로고
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
    • DOI 10.1038/nature04791, PII NATURE04791
    • D. Grimm, K.L. Streetz, C.L. Jopling, T.A. Storm, K. Pandey, C.R. Davis, P. Marion, F. Salazar, and M.A. Kay Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways Nature 441 2006 537 541 (Pubitemid 44050158)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 537-541
    • Grimm, D.1    Streetz, K.L.2    Jopling, C.L.3    Storm, T.A.4    Pandey, K.5    Davis, C.R.6    Marion, P.7    Salazar, F.8    Kay, M.A.9
  • 14
    • 79951854412 scopus 로고    scopus 로고
    • How do miRNAs mediate translational repression?
    • S. Gu, and M.A. Kay How do miRNAs mediate translational repression? Silence 1 2010 11
    • (2010) Silence , vol.1 , pp. 11
    • Gu, S.1    Kay, M.A.2
  • 15
    • 79959366354 scopus 로고    scopus 로고
    • Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes
    • S. Gu, L. Jin, F. Zhang, Y. Huang, D. Grimm, J.J. Rossi, and M.A. Kay Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes Proc. Natl. Acad. Sci. USA 108 2011 9208 9213
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 9208-9213
    • Gu, S.1    Jin, L.2    Zhang, F.3    Huang, Y.4    Grimm, D.5    Rossi, J.J.6    Kay, M.A.7
  • 16
    • 84861391272 scopus 로고    scopus 로고
    • In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs
    • A.M. Gurtan, V. Lu, A. Bhutkar, and P.A. Sharp In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs RNA 18 2012 1116 1122
    • (2012) RNA , vol.18 , pp. 1116-1122
    • Gurtan, A.M.1    Lu, V.2    Bhutkar, A.3    Sharp, P.A.4
  • 17
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • DOI 10.1126/science.1064023
    • S.M. Hammond, S. Boettcher, A.A. Caudy, R. Kobayashi, and G.J. Hannon Argonaute2, a link between genetic and biochemical analyses of RNAi Science 293 2001 1146 1150 (Pubitemid 32758097)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 18
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
    • E. Huntzinger, and E. Izaurralde Gene silencing by microRNAs: contributions of translational repression and mRNA decay Nat. Rev. Genet. 12 2011 99 110
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 19
    • 74049124186 scopus 로고    scopus 로고
    • Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
    • A.L. Jackson, and P.S. Linsley Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application Nat. Rev. Drug Discov. 9 2010 57 67
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 57-67
    • Jackson, A.L.1    Linsley, P.S.2
  • 20
    • 84864326893 scopus 로고    scopus 로고
    • Molecular biology. Use and abuse of RNAi to study mammalian gene function
    • W.G. Kaelin Jr. Molecular biology. Use and abuse of RNAi to study mammalian gene function Science 337 2012 421 422
    • (2012) Science , vol.337 , pp. 421-422
    • Kaelin, Jr.W.G.1
  • 21
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • DOI 10.1016/S0092-8674(03)00801-8
    • A. Khvorova, A. Reynolds, and S.D. Jayasena Functional siRNAs and miRNAs exhibit strand bias Cell 115 2003 209 216 (Pubitemid 37329584)
    • (2003) Cell , vol.115 , Issue.2 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 22
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • D.H. Kim, and J.J. Rossi Strategies for silencing human disease using RNA interference Nat. Rev. Genet. 8 2007 173 184
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 24
    • 78651293534 scopus 로고    scopus 로고
    • MiRBase: Integrating microRNA annotation and deep-sequencing data
    • A. Kozomara, and S. Griffiths-Jones miRBase: integrating microRNA annotation and deep-sequencing data Nucleic Acids Res. 39 Database issue 2011 D152 D157
    • (2011) Nucleic Acids Res. , vol.39 , Issue.DATABASE ISSUE
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 25
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • B. Langmead, C. Trapnell, M. Pop, and S.L. Salzberg Ultrafast and memory-efficient alignment of short DNA sequences to the human genome Genome Biol. 10 2009 R25
    • (2009) Genome Biol. , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 26
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • DOI 10.1126/science.1065062
    • N.C. Lau, L.P. Lim, E.G. Weinstein, and D.P. Bartel An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans Science 294 2001 858 862 (Pubitemid 33032104)
    • (2001) Science , vol.294 , Issue.5543 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 28
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian MicroRNA targets
    • DOI 10.1016/S0092-8674(03)01018-3
    • B.P. Lewis, I.H. Shih, M.W. Jones-Rhoades, D.P. Bartel, and C.B. Burge Prediction of mammalian microRNA targets Cell 115 2003 787 798 (Pubitemid 38058492)
    • (2003) Cell , vol.115 , Issue.7 , pp. 787-798
    • Lewis, B.P.1    Shih, I.-H.2    Jones-Rhoades, M.W.3    Bartel, D.P.4    Burge, C.B.5
  • 29
    • 77953635299 scopus 로고    scopus 로고
    • Biochemical principles of small RNA pathways
    • Q. Liu, and Z. Paroo Biochemical principles of small RNA pathways Annu. Rev. Biochem. 79 2010 295 319
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 295-319
    • Liu, Q.1    Paroo, Z.2
  • 30
    • 44649136660 scopus 로고    scopus 로고
    • Autoinhibition of human dicer by its internal helicase domain
    • E. Ma, I.J. MacRae, J.F. Kirsch, and J.A. Doudna Autoinhibition of human dicer by its internal helicase domain J. Mol. Biol. 380 2008 237 243
    • (2008) J. Mol. Biol. , vol.380 , pp. 237-243
    • Ma, E.1    MacRae, I.J.2    Kirsch, J.F.3    Doudna, J.A.4
  • 31
    • 30844438338 scopus 로고    scopus 로고
    • Structural basis for double-stranded RNA processing by Dicer
    • DOI 10.1126/science.1121638
    • I.J. Macrae, K. Zhou, F. Li, A. Repic, A.N. Brooks, W.Z. Cande, P.D. Adams, and J.A. Doudna Structural basis for double-stranded RNA processing by Dicer Science 311 2006 195 198 (Pubitemid 43108178)
    • (2006) Science , vol.311 , Issue.5758 , pp. 195-198
    • MacRae, I.J.1    Zhou, K.2    Li, F.3    Repic, A.4    Brooks, A.N.5    Cande, W.Z.6    Adams, P.D.7    Doudna, J.A.8
  • 32
    • 34948901976 scopus 로고    scopus 로고
    • Structural determinants of RNA recognition and cleavage by Dicer
    • DOI 10.1038/nsmb1293, PII NSMB1293
    • I.J. MacRae, K. Zhou, and J.A. Doudna Structural determinants of RNA recognition and cleavage by Dicer Nat. Struct. Mol. Biol. 14 2007 934 940 (Pubitemid 47525174)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.10 , pp. 934-940
    • MacRae, I.J.1    Zhou, K.2    Doudna, J.A.3
  • 33
    • 79952818830 scopus 로고    scopus 로고
    • EGO-1, a C. elegans RdRP, modulates gene expression via production of mRNA-templated short antisense RNAs
    • J.M. Maniar, and A.Z. Fire EGO-1, a C. elegans RdRP, modulates gene expression via production of mRNA-templated short antisense RNAs Curr. Biol. 21 2011 449 459
    • (2011) Curr. Biol. , vol.21 , pp. 449-459
    • Maniar, J.M.1    Fire, A.Z.2
  • 35
    • 79961102375 scopus 로고    scopus 로고
    • The effects of stem length and core placement on shRNA activity
    • G.J. McIntyre, Y.H. Yu, M. Lomas, and G.C. Fanning The effects of stem length and core placement on shRNA activity BMC Mol. Biol. 12 2011 34
    • (2011) BMC Mol. Biol. , vol.12 , pp. 34
    • McIntyre, G.J.1    Yu, Y.H.2    Lomas, M.3    Fanning, G.C.4
  • 36
    • 0036273940 scopus 로고    scopus 로고
    • Gene silencing using micro-RNA designed hairpins
    • DOI 10.1017/S1355838202024032
    • M.T. McManus, C.P. Petersen, B.B. Haines, J. Chen, and P.A. Sharp Gene silencing using micro-RNA designed hairpins RNA 8 2002 842 850 (Pubitemid 34620459)
    • (2002) RNA , vol.8 , Issue.6 , pp. 842-850
    • McManus, M.T.1    Petersen, C.P.2    Haines, B.B.3    Chen, J.4    Sharp, P.A.5
  • 37
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • DOI 10.1101/gad.981002
    • P.J. Paddison, A.A. Caudy, E. Bernstein, G.J. Hannon, and D.S. Conklin Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells Genes Dev. 16 2002 948 958 (Pubitemid 34408544)
    • (2002) Genes and Development , vol.16 , Issue.8 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 42
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • DOI 10.1016/S0092-8674(03)00759-1
    • D.S. Schwarz, G. Hutvágner, T. Du, Z. Xu, N. Aronin, and P.D. Zamore Asymmetry in the assembly of the RNAi enzyme complex Cell 115 2003 199 208 (Pubitemid 37329583)
    • (2003) Cell , vol.115 , Issue.2 , pp. 199-208
    • Schwarz, D.S.1    Hutvagner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 43
    • 38349081145 scopus 로고    scopus 로고
    • Argonaute loading improves the 5′ precision of both MicroRNAs and their miRNA strands in flies
    • H. Seitz, M. Ghildiyal, and P.D. Zamore Argonaute loading improves the 5′ precision of both MicroRNAs and their miRNA strands in flies Curr. Biol. 18 2008 147 151
    • (2008) Curr. Biol. , vol.18 , pp. 147-151
    • Seitz, H.1    Ghildiyal, M.2    Zamore, P.D.3
  • 44
    • 84856542174 scopus 로고    scopus 로고
    • A 5′-uridine amplifies miRNA/miRNA asymmetry in Drosophila by promoting RNA-induced silencing complex formation
    • H. Seitz, J.S. Tushir, and P.D. Zamore A 5′-uridine amplifies miRNA/miRNA asymmetry in Drosophila by promoting RNA-induced silencing complex formation Silence 2 2011 4
    • (2011) Silence , vol.2 , pp. 4
    • Seitz, H.1    Tushir, J.S.2    Zamore, P.D.3
  • 49
  • 50
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • DOI 10.1016/S1097-2765(02)00541-5
    • Y. Zeng, E.J. Wagner, and B.R. Cullen Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells Mol. Cell 9 2002 1327 1333 (Pubitemid 34722311)
    • (2002) Molecular Cell , vol.9 , Issue.6 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 51
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • DOI 10.1093/emboj/cdf582
    • H. Zhang, F.A. Kolb, V. Brondani, E. Billy, and W. Filipowicz Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP EMBO J. 21 2002 5875 5885 (Pubitemid 35315285)
    • (2002) EMBO Journal , vol.21 , Issue.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 52
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • DOI 10.1016/j.cell.2004.06.017, PII S009286740400618X
    • H. Zhang, F.A. Kolb, L. Jaskiewicz, E. Westhof, and W. Filipowicz Single processing center models for human Dicer and bacterial RNase III Cell 118 2004 57 68 (Pubitemid 38902814)
    • (2004) Cell , vol.118 , Issue.1 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5


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