-
1
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E., Caudy A.A., Hammond S.M., and Hannon G.J. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363.
-
(2001)
Nature
, vol.409
, pp. 363
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
2
-
-
0035807818
-
Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
-
Billy E., Brondani V., Zhang H., Muller U., and Filipowicz W. 2001. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc. Natl. Acad. Sci. 98: 14428.
-
(2001)
Proc. Natl. Acad. Sci
, vol.98
, pp. 14428
-
-
Billy, E.1
Brondani, V.2
Zhang, H.3
Muller, U.4
Filipowicz, W.5
-
3
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada T.P., Gregory R.I., Kumaraswamy E., Norman J., Cooch N., Nishikura K., and Shiekhattar R. 2005. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436: 740.
-
(2005)
Nature
, vol.436
, pp. 740
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
Norman, J.4
Cooch, N.5
Nishikura, K.6
Shiekhattar, R.7
-
4
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir S.M., Lendeckel W., and Tuschl T. 2001. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15: 188.
-
(2001)
Genes Dev
, vol.15
, pp. 188
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
5
-
-
2342443461
-
Protein displacement by DExH/D "RNA helicases" without duplex unwinding
-
Fairman M.E., Maroney P.A., Wang W., Bowers H.A., Gollnick P., Nilsen T.W., and Jankowsky E. 2004. Protein displacement by DExH/D "RNA helicases" without duplex unwinding. Science 304: 730.
-
(2004)
Science
, vol.304
, pp. 730
-
-
Fairman, M.E.1
Maroney, P.A.2
Wang, W.3
Bowers, H.A.4
Gollnick, P.5
Nilsen, T.W.6
Jankowsky, E.7
-
6
-
-
31044448524
-
Structural insight into the mechanism of double-stranded RNA processing by ribonuclease III
-
Gan J., Tropea J.E., Austin B.P., Court D.L., Waugh D.S., and Ji X. 2006. Structural insight into the mechanism of double-stranded RNA processing by ribonuclease III. Cell 124: 355.
-
(2006)
Cell
, vol.124
, pp. 355
-
-
Gan, J.1
Tropea, J.E.2
Austin, B.P.3
Court, D.L.4
Waugh, D.S.5
Ji, X.6
-
7
-
-
27744537851
-
Human RISC couples microRNA biogenesis and post-transcriptional gene silencing
-
Gregory R.I., Chendrimada T.P., Cooch N., and Shiekhattar R. 2005. Human RISC couples microRNA biogenesis and post-transcriptional gene silencing. Cell 123: 631.
-
(2005)
Cell
, vol.123
, pp. 631
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
8
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond S.M., Bernstein E., Beach D., and Hannon G.J. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404: 293.
-
(2000)
Nature
, vol.404
, pp. 293
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
9
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond S.M., Boettcher S., Caudy A.A., Kobayashi R., and Hannon G.J. 2001. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293: 1146.
-
(2001)
Science
, vol.293
, pp. 1146
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
10
-
-
0037062951
-
RNA interference
-
Hannon G.J. 2002. RNA interference. Nature 418: 244.
-
(2002)
Nature
, vol.418
, pp. 244
-
-
Hannon, G.J.1
-
11
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G., McLachlan J., Pasquinelli A.E., Balint E., Tuschl T., and Zamore P.D. 2001. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293: 834.
-
(2001)
Science
, vol.293
, pp. 834
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
12
-
-
0035808566
-
Active disruption of an RNA-protein interaction by a DExH/D RNA helicase
-
Jankowsky E., Gross C.H., Shuman S., and Pyle A.M. 2001. Active disruption of an RNA-protein interaction by a DExH/D RNA helicase. Science 291: 121.
-
(2001)
Science
, vol.291
, pp. 121
-
-
Jankowsky, E.1
Gross, C.H.2
Shuman, S.3
Pyle, A.M.4
-
13
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting R.F., Fischer S.E., Bernstein E., Sijen T., Hannon G.J., and Plasterk R.H. 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15: 2654.
-
(2001)
Genes Dev
, vol.15
, pp. 2654
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
14
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A., Reynolds A., and Jayasena S.D. 2003. Functional siRNAs and miRNAs exhibit strand bias. Cell 115: 209.
-
(2003)
Cell
, vol.115
, pp. 209
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
15
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
Kim D.H., Behlke M.A., Rose S.D., Chang M.S., Choi S., and Rossi J.J. 2005. Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat. Biotechnol. 23: 222.
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 222
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
16
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
Lau N.C., Lim L.P., Weinstein E.G., and Bartel D.P. 2001. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858.
-
(2001)
Science
, vol.294
, pp. 858
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
17
-
-
32544460452
-
The role of PACT in the RNA silencing pathway
-
Lee Y., Hur I., Park S.Y., Kim Y.K., Suh M.R., and Kim V.N. 2006. The role of PACT in the RNA silencing pathway. EMBO J. 25: 522.
-
(2006)
EMBO J
, vol.25
, pp. 522
-
-
Lee, Y.1
Hur, I.2
Park, S.Y.3
Kim, Y.K.4
Suh, M.R.5
Kim, V.N.6
-
18
-
-
0141868916
-
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
-
Liu Q., Rand T.A., Kalidas S., Du F., Kim H.E., Smith D.P., and Wang X. 2003. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301: 1921.
-
(2003)
Science
, vol.301
, pp. 1921
-
-
Liu, Q.1
Rand, T.A.2
Kalidas, S.3
Du, F.4
Kim, H.E.5
Smith, D.P.6
Wang, X.7
-
19
-
-
0035095521
-
Large-scale purification of a stable form of recombinant tobacco etch virus protease
-
Lucast L.J., Batey R.T., and Doudna J.A. 2001. Large-scale purification of a stable form of recombinant tobacco etch virus protease. Biotechniques 30: 544.
-
(2001)
Biotechniques
, vol.30
, pp. 544
-
-
Lucast, L.J.1
Batey, R.T.2
Doudna, J.A.3
-
20
-
-
2442679207
-
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
-
Ma J.B., Ye K., and Patel D.J. 2004. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429: 318.
-
(2004)
Nature
, vol.429
, pp. 318
-
-
Ma, J.B.1
Ye, K.2
Patel, D.J.3
-
21
-
-
30844438338
-
Structural basis for double-stranded RNA processing by Dicer
-
MacRae I.J., Zhou K., Li F., Repic A., Brooks A.N., Cande W.Z., Adams P.D., and Doudna J.A. 2006. Structural basis for double-stranded RNA processing by Dicer. Science 311: 195.
-
(2006)
Science
, vol.311
, pp. 195
-
-
MacRae, I.J.1
Zhou, K.2
Li, F.3
Repic, A.4
Brooks, A.N.5
Cande, W.Z.6
Adams, P.D.7
Doudna, J.A.8
-
22
-
-
29144431656
-
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
-
Maniataki E. and Mourelatos Z. 2005. A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev. 19: 2979.
-
(2005)
Genes Dev
, vol.19
, pp. 2979
-
-
Maniataki, E.1
Mourelatos, Z.2
-
23
-
-
0026025891
-
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
-
Moreno S., Klar A., and Nurse P. 1991. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194: 795.
-
(1991)
Methods Enzymol
, vol.194
, pp. 795
-
-
Moreno, S.1
Klar, A.2
Nurse, P.3
-
24
-
-
0037335550
-
Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing
-
Myers J.W., Jones J.T., Meyer T., and Ferrell J.E., Jr. 2003. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat. Biotechnol. 21: 324.
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 324
-
-
Myers, J.W.1
Jones, J.T.2
Meyer, T.3
Ferrell Jr., J.E.4
-
25
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
-
Pasquinelli A.E., Reinhart B.J., Slack F., Martindale M.Q., Kuroda M.I., Maller B., Hayward D.C., Ball E.E., Degnan B., Muller P., et al. 2000. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408: 86.
-
(2000)
Nature
, vol.408
, pp. 86
-
-
Pasquinelli, A.E.1
Reinhart, B.J.2
Slack, F.3
Martindale, M.Q.4
Kuroda, M.I.5
Maller, B.6
Hayward, D.C.7
Ball, E.E.8
Degnan, B.9
Muller, P.10
-
26
-
-
27144469457
-
ATP modulates siRNA interactions with an endogenous human Dicer complex
-
Pellino J.L., Jaskiewicz L., Filipowicz W., and Sontheimer E.J. 2005. ATP modulates siRNA interactions with an endogenous human Dicer complex. RNA 11: 1719.
-
(2005)
RNA
, vol.11
, pp. 1719
-
-
Pellino, J.L.1
Jaskiewicz, L.2
Filipowicz, W.3
Sontheimer, E.J.4
-
27
-
-
24644480213
-
Inhibition of translational initiation by Let-7 MicroRNA in human cells
-
Pillai R.S., Bhattacharyya S.N., Artus C.G., Zoller T., Cougot N., Basyuk E., Bertrand E., and Filipowicz W. 2005. Inhibition of translational initiation by Let-7 MicroRNA in human cells. Science 309: 1573.
-
(2005)
Science
, vol.309
, pp. 1573
-
-
Pillai, R.S.1
Bhattacharyya, S.N.2
Artus, C.G.3
Zoller, T.4
Cougot, N.5
Basyuk, E.6
Bertrand, E.7
Filipowicz, W.8
-
28
-
-
22844448088
-
Functional polarity is introduced by Dicer processing of short substrate RNAs
-
Rose S.D., Kim D.H., Amarzguioui M., Heidel J.D., Collingwood M.A., Davis M.E., Rossi J.J., and Behlke M.A. 2005. Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res. 33: 4140.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4140
-
-
Rose, S.D.1
Kim, D.H.2
Amarzguioui, M.3
Heidel, J.D.4
Collingwood, M.A.5
Davis, M.E.6
Rossi, J.J.7
Behlke, M.A.8
-
29
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz D.S., Hutvagner G., Du T., Xu Z., Aronin N., and Zamore P.D. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115: 199.
-
(2003)
Cell
, vol.115
, pp. 199
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
30
-
-
33344464450
-
Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsensemediated mRNA decay
-
Shibuya T., Tange T.O., Stroupe M.E., and Moore M.J. 2006. Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsensemediated mRNA decay. RNA 12: 360.
-
(2006)
RNA
, vol.12
, pp. 360
-
-
Shibuya, T.1
Tange, T.O.2
Stroupe, M.E.3
Moore, M.J.4
-
31
-
-
4444302947
-
Crystal structure of Argonaute and its implications for RISC slicer activity
-
Song J.J., Smith S.K., Hannon G.J., and Joshua-Tor L. 2004. Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305: 1434.
-
(2004)
Science
, vol.305
, pp. 1434
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
32
-
-
0345490960
-
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
-
Song J.J., Liu J., Tolia N.H., Schneiderman J., Smith S.K., Martienssen R.A., Hannon G.J., and Joshua-Tor L. 2003. The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat. Struct. Biol. 10: 1026.
-
(2003)
Nat. Struct. Biol
, vol.10
, pp. 1026
-
-
Song, J.J.1
Liu, J.2
Tolia, N.H.3
Schneiderman, J.4
Smith, S.K.5
Martienssen, R.A.6
Hannon, G.J.7
Joshua-Tor, L.8
-
33
-
-
3242875210
-
ElNemo: A normal mode web server for protein movement analysis and the generation of templates for molecular replacement
-
Suhre K. and Sanejouand Y.H. 2004. ElNemo: A normal mode web server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Res. 32: W610.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Suhre, K.1
Sanejouand, Y.H.2
-
34
-
-
8844271740
-
A protein sensor for siRNA asymmetry
-
Tomari Y., Matranga C., Haley B., Martinez N., and Zamore P.D. 2004a. A protein sensor for siRNA asymmetry. Science 306: 1377.
-
(2004)
Science
, vol.306
, pp. 1377
-
-
Tomari, Y.1
Matranga, C.2
Haley, B.3
Martinez, N.4
Zamore, P.D.5
-
35
-
-
1642603943
-
RISC assembly defects in the Drosophila RNAi mutant armitage
-
Tomari Y., Du T., Haley B., Schwarz D.S., Bennett R., Cook H.A., Koppetsch B.S., Theurkauf W.E., and Zamore P.D. 2004b. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116: 831.
-
(2004)
Cell
, vol.116
, pp. 831
-
-
Tomari, Y.D.T.1
Haley, B.2
Schwarz, D.S.3
Bennett, R.4
Cook, H.A.5
Koppetsch, B.S.6
Theurkauf, W.E.7
Zamore, P.D.8
-
36
-
-
0942279635
-
RNAi-mediated targeting of heterochromatin by the RITS complex
-
Verdel A., Jia S., Gerber S., Sugiyama T., Gygi S., Grewal S.I., and Moazed D. 2004. RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303: 672.
-
(2004)
Science
, vol.303
, pp. 672
-
-
Verdel, A.1
Jia, S.2
Gerber, S.3
Sugiyama, T.4
Gygi, S.5
Grewal, S.I.6
Moazed, D.7
-
37
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
-
Zhang H., Kolb F.A., Brondani V., Billy E., and Filipowicz W. 2002. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J. 21: 5875.
-
(2002)
EMBO J
, vol.21
, pp. 5875
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
38
-
-
3142613181
-
Single processing center models for human Dicer and bacterial RNase III
-
Zhang H., Kolb F.A., Jaskiewicz L., Westhof E., and Filipowicz W. 2004. Single processing center models for human Dicer and bacterial RNase III. Cell 118: 57.
-
(2004)
Cell
, vol.118
, pp. 57
-
-
Zhang, H.1
Kolb, F.A.2
Jaskiewicz, L.3
Westhof, E.4
Filipowicz, W.5
|