In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs

RNA

Volumn 18, Issue 6, 2012, Pages 1116-1122

  Gurtan, Allan M ^a   Lu, Victoria ^a,b   Bhutkar, Arjun ^a   Sharp, Phillip A ^a,b  

^a David H Koch Institute for Integrative Cancer Research   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cancer; Dicer; Helicase; miRNA; PAZ; RNase III

Indexed keywords

DICER; HELICASE; MICRORNA; RNA PRECURSOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; GENE MUTATION; HUMAN; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; RNA PROCESSING;

ANIMALS; CELL LINE; DEAD-BOX RNA HELICASES; GENE KNOCKOUT TECHNIQUES; HUMANS; MESENCHYMAL STEM CELLS; MICE; MICRORNAS; MUTATION; RIBONUCLEASE III; RNA PRECURSORS; STRUCTURE-ACTIVITY RELATIONSHIP;

MURINAE;

EID: 84861391272     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.032680.112     Document Type: Article

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