-
1
-
-
84872761427
-
Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii
-
Koblansky AA, Jankovic D, Oh H, et al. Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii. Immunity 2013; 38(1): 119-30.
-
(2013)
Immunity
, vol.38
, Issue.1
, pp. 119-130
-
-
Koblansky, A.A.1
Jankovic, D.2
Oh, H.3
-
2
-
-
84865571191
-
TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification
-
Oldenburg M, Kruger A, Ferstl R, et al. TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. Science 2012; 337(6098): 1111-5.
-
(2012)
Science
, vol.337
, Issue.6098
, pp. 1111-1115
-
-
Oldenburg, M.1
Kruger, A.2
Ferstl, R.3
-
3
-
-
84880923978
-
Newly described pattern recognition receptors team up against intracellular pathogens
-
Broz P, Monack DM. Newly described pattern recognition receptors team up against intracellular pathogens. Nat Rev Immunol 2013; 13(8): 551-65.
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.8
, pp. 551-565
-
-
Broz, P.1
Monack, D.M.2
-
4
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart CR, Stuart LM, Wilkinson K, et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol 2010; 11(2): 155-61.
-
(2010)
Nat Immunol
, vol.11
, Issue.2
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
-
5
-
-
33750312909
-
Emerging paradigm: Tolllike receptor 4-sentinel for the detection of tissue damage
-
Mollen KP, Anand RJ, Tsung A, et al. Emerging paradigm: tolllike receptor 4-sentinel for the detection of tissue damage. Shock (Augusta, Ga) 2006; 26(5): 430-7.
-
(2006)
Shock (Augusta, Ga)
, vol.26
, Issue.5
, pp. 430-437
-
-
Mollen, K.P.1
Anand, R.J.2
Tsung, A.3
-
6
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010; 11(5): 373-84.
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
7
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4(7): 499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.7
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
8
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2(8): 675-80.
-
(2001)
Nat Immunol
, vol.2
, Issue.8
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
10
-
-
44349132270
-
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
-
Artis D. Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 2008; 8(6): 411-20.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.6
, pp. 411-420
-
-
Artis, D.1
-
11
-
-
0037434974
-
Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
-
Treiner E, Duban L, Bahram S, et al. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 2003; 422(6928): 164-9.
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 164-169
-
-
Treiner, E.1
Duban, L.2
Bahram, S.3
-
12
-
-
44349167059
-
Dendritic cells in intestinal immune regulation
-
Coombes JL, Powrie F. Dendritic cells in intestinal immune regulation. Nat Rev Immunol 2008; 8(6): 435-46.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.6
, pp. 435-446
-
-
Coombes, J.L.1
Powrie, F.2
-
14
-
-
84905399513
-
Toll-like receptor 4 activation in Barrett's esophagus results in a strong increase in COX-2 expression
-
Verbeek RE, Siersema PD, Ten Kate FJ, et al. Toll-like receptor 4 activation in Barrett's esophagus results in a strong increase in COX-2 expression. J Gastroenterol 2014; 49(7): 1121-34.
-
(2014)
J Gastroenterol
, vol.49
, Issue.7
, pp. 1121-1134
-
-
Verbeek, R.E.1
Siersema, P.D.2
Ten Kate, F.J.3
-
15
-
-
80052745459
-
Increased expression of toll-like receptors (TLR) 2, 4 and 5 in gastric dysplasia
-
Pimentel-Nunes P, Afonso L, Lopes P, et al. Increased expression of toll-like receptors (TLR) 2, 4 and 5 in gastric dysplasia. Pathol Oncol Res 2011; 17(3): 677-83.
-
(2011)
Pathol Oncol Res
, vol.17
, Issue.3
, pp. 677-683
-
-
Pimentel-Nunes, P.1
Afonso, L.2
Lopes, P.3
-
16
-
-
2542510727
-
Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection
-
Schmausser B, Andrulis M, Endrich S, et al. Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection. Clin Exp Immunol 2004; 136(3): 521-6.
-
(2004)
Clin Exp Immunol
, vol.136
, Issue.3
, pp. 521-526
-
-
Schmausser, B.1
Andrulis, M.2
Endrich, S.3
-
17
-
-
0035424901
-
Decreased expression of Tolllike receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
Abreu MT, Vora P, Faure E, et al. Decreased expression of Tolllike receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol (Baltimore, Md: 1950) 2001; 167(3): 1609-16.
-
(2001)
J Immunol (Baltimore, Md: 1950)
, vol.167
, Issue.3
, pp. 1609-1616
-
-
Abreu, M.T.1
Vora, P.2
Faure, E.3
-
18
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 2000; 68(12): 7010-7.
-
(2000)
Infect Immun
, vol.68
, Issue.12
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
19
-
-
22744453319
-
Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria
-
Furrie E, Macfarlane S, Thomson G, et al. Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria. Immunology 2005; 115(4): 565-74.
-
(2005)
Immunology
, vol.115
, Issue.4
, pp. 565-574
-
-
Furrie, E.1
Macfarlane, S.2
Thomson, G.3
-
20
-
-
0037307854
-
Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: Implications for host-microbial interactions in the gut
-
Melmed G, Thomas LS, Lee N, et al. Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J Immunol 2003; 170(3): 1406-15.
-
(2003)
J Immunol
, vol.170
, Issue.3
, pp. 1406-1415
-
-
Melmed, G.1
Thomas, L.S.2
Lee, N.3
-
21
-
-
75649093343
-
Toll-like receptor signalling in the intestinal epithelium: How bacterial recognition shapes intestinal function
-
Abreu MT. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol 2010; 10(2): 131-44.
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.2
, pp. 131-144
-
-
Abreu, M.T.1
-
22
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, et al. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 2004; 118(2): 229-41.
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
-
23
-
-
0037036469
-
TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells
-
Abreu MT, Arnold ET, Thomas LS, et al. TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J Biol Chem 2002; 277(23): 20431-7.
-
(2002)
J Biol Chem
, vol.277
, Issue.23
, pp. 20431-20437
-
-
Abreu, M.T.1
Arnold, E.T.2
Thomas, L.S.3
-
24
-
-
0038781673
-
Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex
-
Suzuki M, Hisamatsu T, Podolsky DK. Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex. Infect Immun 2003; 71(6): 3503-11.
-
(2003)
Infect Immun
, vol.71
, Issue.6
, pp. 3503-3511
-
-
Suzuki, M.1
Hisamatsu, T.2
Podolsky, D.K.3
-
25
-
-
0042733592
-
SIGIRR, a negative regulator of Tolllike receptor-interleukin 1 receptor signaling
-
Wald D, Qin J, Zhao Z, et al. SIGIRR, a negative regulator of Tolllike receptor-interleukin 1 receptor signaling. Nat Immunol 2003; 4(9): 920-7.
-
(2003)
Nat Immunol
, vol.4
, Issue.9
, pp. 920-927
-
-
Wald, D.1
Qin, J.2
Zhao, Z.3
-
26
-
-
12144287484
-
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family
-
Garlanda C, Riva F, Polentarutti N, et al. Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc Natl Acad Sci USA 2004; 101(10): 3522-6.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.10
, pp. 3522-3526
-
-
Garlanda, C.1
Riva, F.2
Polentarutti, N.3
-
27
-
-
34247175428
-
The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis
-
Xiao H, Gulen MF, Qin J, et al. The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity 2007; 26(4): 461-75.
-
(2007)
Immunity
, vol.26
, Issue.4
, pp. 461-475
-
-
Xiao, H.1
Gulen, M.F.2
Qin, J.3
-
28
-
-
1842583729
-
Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells
-
Otte JM, Cario E, Podolsky DK. Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 2004; 126(4): 1054-70.
-
(2004)
Gastroenterology
, vol.126
, Issue.4
, pp. 1054-1070
-
-
Otte, J.M.1
Cario, E.2
Podolsky, D.K.3
-
29
-
-
84907597269
-
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4
-
Venkatesh M, Mukherjee S, Wang H, et al. Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4. Immunity 2014; 41(2): 296-310.
-
(2014)
Immunity
, vol.41
, Issue.2
, pp. 296-310
-
-
Venkatesh, M.1
Mukherjee, S.2
Wang, H.3
-
30
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
Gewirtz AT, Navas TA, Lyons S, et al. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol (Baltimore, Md: 1950) 2001; 167(4): 1882-5.
-
(2001)
J Immunol (Baltimore, Md: 1950)
, vol.167
, Issue.4
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
-
31
-
-
0035170239
-
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response
-
Gewirtz AT, Simon PO, Jr., Schmitt CK, et al. Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. J Clin Invest 2001; 107(1): 99-109.
-
(2001)
J Clin Invest
, vol.107
, Issue.1
, pp. 99-109
-
-
Gewirtz, A.T.1
Simon, P.O.2
Schmitt, C.K.3
-
32
-
-
26444440067
-
Pathophysiological role of Tolllike receptor 5 engagement by bacterial flagellin in colonic inflammation
-
Rhee SH, Im E, Riegler M, et al. Pathophysiological role of Tolllike receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci USA 2005; 102(38): 13610-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.38
, pp. 13610-13615
-
-
Rhee, S.H.1
Im, E.2
Riegler, M.3
-
33
-
-
34248397191
-
Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA
-
Ewaschuk JB, Backer JL, Churchill TA, et al. Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA. Infect Immun 2007; 75(5): 2572-9.
-
(2007)
Infect Immun
, vol.75
, Issue.5
, pp. 2572-2579
-
-
Ewaschuk, J.B.1
Backer, J.L.2
Churchill, T.A.3
-
34
-
-
33751551466
-
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
-
Lee J, Mo JH, Katakura K, et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol 2006; 8(12): 1327-U7.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.12
, pp. 1327
-
-
Lee, J.1
Mo, J.H.2
Katakura, K.3
-
35
-
-
0038604293
-
Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-kappaBindependent pathway
-
Akhtar M, Watson JL, Nazli A, et al. Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-kappaBindependent pathway. FASEB J 2003; 17(10): 1319-21.
-
(2003)
FASEB J
, vol.17
, Issue.10
, pp. 1319-1321
-
-
Akhtar, M.1
Watson, J.L.2
Nazli, A.3
-
36
-
-
3242692641
-
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
-
Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology 2004; 127(1): 224-38.
-
(2004)
Gastroenterology
, vol.127
, Issue.1
, pp. 224-238
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
37
-
-
38049174332
-
Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitis
-
Gibson DL, Ma C, Rosenberger CM, et al. Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitis. Cell Microbiol 2008; 10(2): 388- 403.
-
(2008)
Cell Microbiol
, vol.10
, Issue.2
, pp. 388-403
-
-
Gibson, D.L.1
Ma, C.2
Rosenberger, C.M.3
-
38
-
-
68149091349
-
Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism
-
Slack E, Hapfelmeier S, Stecher B, et al. Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science 2009; 325(5940): 617-20.
-
(2009)
Science
, vol.325
, Issue.5940
, pp. 617-620
-
-
Slack, E.1
Hapfelmeier, S.2
Stecher, B.3
-
39
-
-
34247235029
-
Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
-
Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 2007; 132(4): 1359-74.
-
(2007)
Gastroenterology
, vol.132
, Issue.4
, pp. 1359-1374
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
40
-
-
79956139648
-
Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium
-
Clarke TB, Francella N, Huegel A, et al. Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium. Cell Host Microbe 2011; 9(5): 404-14.
-
(2011)
Cell Host Microbe
, vol.9
, Issue.5
, pp. 404-414
-
-
Clarke, T.B.1
Francella, N.2
Huegel, A.3
-
41
-
-
84892482473
-
Induction of Innate Lymphoid Cell- Derived Interleukin-22 by the Transcription Factor STAT3 Mediates Protection against Intestinal Infection
-
Guo XH, Qiu J, Tu T, et al. Induction of Innate Lymphoid Cell- Derived Interleukin-22 by the Transcription Factor STAT3 Mediates Protection against Intestinal Infection. Immunity 2014; 40(1): 25-39.
-
(2014)
Immunity
, vol.40
, Issue.1
, pp. 25-39
-
-
Guo, X.H.1
Qiu, J.2
Tu, T.3
-
42
-
-
79955567841
-
DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma
-
Sodhi C, Levy R, Gill R, et al. DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma. Am J Physiol Gastrointestinal Liver Physiol 2011; 300(5): G862- 73.
-
(2011)
Am J Physiol Gastrointestinal Liver Physiol
, vol.300
, Issue.5
, pp. 73-862
-
-
Sodhi, C.1
Levy, R.2
Gill, R.3
-
43
-
-
20244373939
-
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
-
Tsung A, Sahai R, Tanaka H, et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med 2005; 201(7): 1135-43.
-
(2005)
J Exp Med
, vol.201
, Issue.7
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
-
45
-
-
20444373390
-
MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis
-
Araki A, Kanai T, Ishikura T, et al. MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis. J Gastroenterol 2005; 40(1): 16-23.
-
(2005)
J Gastroenterol
, vol.40
, Issue.1
, pp. 16-23
-
-
Araki, A.1
Kanai, T.2
Ishikura, T.3
-
46
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
Fukata M, Michelsen KS, Eri R, et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointestinal Liver Physiol 2005; 288(5): G1055-65.
-
(2005)
Am J Physiol Gastrointestinal Liver Physiol
, vol.288
, Issue.5
, pp. 1055-1065
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
-
47
-
-
78149486988
-
Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis
-
Khailova L, Patrick MSK, Arganbright KM, et al. Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis. Am J Physiol Gastrointestinal Liver Physiol 2010; 299(5): G1118-27.
-
(2010)
Am J Physiol Gastrointestinal Liver Physiol
, vol.299
, Issue.5
, pp. 1118-1127
-
-
Khailova, L.1
Patrick, M.S.K.2
Arganbright, K.M.3
-
48
-
-
84860575266
-
Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclooxygenase- 2-dependent manner
-
Ciorba MA, Riehl TE, Rao MS, et al. Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclooxygenase- 2-dependent manner. Gut 2012; 61(6): 829-38.
-
(2012)
Gut
, vol.61
, Issue.6
, pp. 829-838
-
-
Ciorba, M.A.1
Riehl, T.E.2
Rao, M.S.3
-
49
-
-
33846017279
-
Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury
-
Brown SL, Riehl TE, Walker MR, et al. Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury. J Clin Invest 2007; 117(1): 258-69.
-
(2007)
J Clin Invest
, vol.117
, Issue.1
, pp. 258-269
-
-
Brown, S.L.1
Riehl, T.E.2
Walker, M.R.3
-
50
-
-
33748271299
-
Cox-2 is regulated by Tolllike receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine
-
Fukata M, Chen A, Klepper A, et al. Cox-2 is regulated by Tolllike receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine. Gastroenterology 2006; 131(3): 862-77.
-
(2006)
Gastroenterology
, vol.131
, Issue.3
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
-
51
-
-
37849033136
-
Role of Toll-like receptors in gastrointestinal malignancies
-
Fukata M, Abreu MT. Role of Toll-like receptors in gastrointestinal malignancies. Oncogene 2008; 27(2): 234-43.
-
(2008)
Oncogene
, vol.27
, Issue.2
, pp. 234-243
-
-
Fukata, M.1
Abreu, M.T.2
-
52
-
-
34848893583
-
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: A cohort study
-
quiz 340-1
-
Gupta RB, Harpaz N, Itzkowitz S, et al. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 2007; 133(4): 1099-105; quiz 340-1.
-
(2007)
Gastroenterology
, vol.133
, Issue.4
, pp. 1099-1105
-
-
Gupta, R.B.1
Harpaz, N.2
Itzkowitz, S.3
-
53
-
-
10744221150
-
Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
-
Rutter M, Saunders B, Wilkinson K, et al. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 2004; 126(2): 451-9.
-
(2004)
Gastroenterology
, vol.126
, Issue.2
, pp. 451-459
-
-
Rutter, M.1
Saunders, B.2
Wilkinson, K.3
-
54
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
-
Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 2007; 317(5834): 124-7.
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 124-127
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
55
-
-
36549082403
-
Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
-
Fukata M, Chen A, Vamadevan AS, et al. Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology 2007; 133(6): 1869-81.
-
(2007)
Gastroenterology
, vol.133
, Issue.6
, pp. 1869-1881
-
-
Fukata, M.1
Chen, A.2
Vamadevan, A.S.3
-
56
-
-
69449102284
-
Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors
-
Fukata M, Hernandez Y, Conduah D, et al. Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors. Inflammat Bowel Diseases 2009; 15(7): 997-1006.
-
(2009)
Inflammat Bowel Diseases
, vol.15
, Issue.7
, pp. 997-1006
-
-
Fukata, M.1
Hernandez, Y.2
Conduah, D.3
-
57
-
-
0141593676
-
Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin
-
Shao J, Lee SB, Guo H, et al. Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin. Cancer Res 2003; 63(17): 5218-23.
-
(2003)
Cancer Res
, vol.63
, Issue.17
, pp. 5218-5223
-
-
Shao, J.1
Lee, S.B.2
Guo, H.3
-
58
-
-
12644261426
-
Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells
-
Coffey RJ, Hawkey CJ, Damstrup L, et al. Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. Proc Natl Acad Sci USA 1997; 94(2): 657-62.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.2
, pp. 657-662
-
-
Coffey, R.J.1
Hawkey, C.J.2
Damstrup, L.3
-
59
-
-
84899428429
-
Role of toll-like receptor 4 in colorectal carcinogenesis: A meta-analysis
-
Li XX, Sun GP, Meng J, et al. Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis. PLoS One 2014; 9(4): e93904.
-
(2014)
PLoS One
, vol.9
, Issue.4
-
-
Li, X.X.1
Sun, G.P.2
Meng, J.3
-
60
-
-
84873973938
-
Chemoprevention of cancers in gastrointestinal tract with cyclooxygenase 2 inhibitors
-
Wang R, Guo L, Wang P, et al. Chemoprevention of cancers in gastrointestinal tract with cyclooxygenase 2 inhibitors. Curr Pharm Des 2013; 19(1): 115-25.
-
(2013)
Curr Pharm Des
, vol.19
, Issue.1
, pp. 115-125
-
-
Wang, R.1
Guo, L.2
Wang, P.3
-
61
-
-
84867192879
-
Intestinal inflammation targets cancer-inducing activity of the microbiota
-
Arthur JC, Perez-Chanona E, Muhlbauer M, et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012; 338(6103): 120-3.
-
(2012)
Science
, vol.338
, Issue.6103
, pp. 120-123
-
-
Arthur, J.C.1
Perez-Chanona, E.2
Muhlbauer, M.3
-
62
-
-
84891276262
-
Functional TLR5 genetic variants affect human colorectal cancer survival
-
Klimosch SN, Forsti A, Eckert J, et al. Functional TLR5 genetic variants affect human colorectal cancer survival. Cancer Res 2013; 73(24): 7232-42.
-
(2013)
Cancer Res
, vol.73
, Issue.24
, pp. 7232-7242
-
-
Klimosch, S.N.1
Forsti, A.2
Eckert, J.3
-
63
-
-
79955531832
-
TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer
-
Castro FA, Forsti A, Buch S, et al. TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer 2011; 47(8): 1203-10.
-
(2011)
Eur J Cancer
, vol.47
, Issue.8
, pp. 1203-1210
-
-
Castro, F.A.1
Forsti, A.2
Buch, S.3
-
64
-
-
0034084438
-
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
-
Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000; 25(2): 187-91.
-
(2000)
Nat Genet
, vol.25
, Issue.2
, pp. 187-191
-
-
Arbour, N.C.1
Lorenz, E.2
Schutte, B.C.3
-
65
-
-
34748867825
-
Toll-like receptor 2 -196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer
-
Tahara T, Arisawa T, Wang F, et al. Toll-like receptor 2 -196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer. Cancer Sci 2007; 98(11): 1790-4.
-
(2007)
Cancer Sci
, vol.98
, Issue.11
, pp. 1790-1794
-
-
Tahara, T.1
Arisawa, T.2
Wang, F.3
-
66
-
-
80053919303
-
Toll-like receptor 3 C1234T may protect against geographic atrophy through decreased dsRNA binding capacity
-
Zhou P, Fan L, Yu KD, et al. Toll-like receptor 3 C1234T may protect against geographic atrophy through decreased dsRNA binding capacity. FASEB J 2011; 25(10): 3489-95.
-
(2011)
FASEB J
, vol.25
, Issue.10
, pp. 3489-3495
-
-
Zhou, P.1
Fan, L.2
Yu, K.D.3
-
67
-
-
0027065034
-
Human gastric carcinogenesis - a multistep and multifactorial process - 1st american-cancer-society award lecture on cancer- epidemiology and prevention
-
Correa P. Human gastric carcinogenesis - a multistep and multifactorial process - 1st american-cancer-society award lecture on cancer- epidemiology and prevention. Cancer Res 1992; 52(24): 6735- 40.
-
(1992)
Cancer Res
, vol.52
, Issue.24
, pp. 40-6735
-
-
Correa, P.1
-
68
-
-
3142727043
-
Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis
-
Ishihara S, Rumi MA, Kadowaki Y, et al. Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis. J Immunol 2004; 173(2): 1406-16.
-
(2004)
J Immunol
, vol.173
, Issue.2
, pp. 1406-1416
-
-
Ishihara, S.1
Rumi, M.A.2
Kadowaki, Y.3
-
69
-
-
29144501209
-
Helicobacter pylori-induced invasion and angiogenesis of gastric cells is mediated by cyclooxygenase- 2 induction through TLR2/TLR9 and promoter regulation
-
Chang YJ, Wu MS, Lin JT, et al. Helicobacter pylori-induced invasion and angiogenesis of gastric cells is mediated by cyclooxygenase- 2 induction through TLR2/TLR9 and promoter regulation. J Immunol 2005; 175(12): 8242-52.
-
(2005)
J Immunol
, vol.175
, Issue.12
, pp. 8242-8252
-
-
Chang, Y.J.1
Wu, M.S.2
Lin, J.T.3
-
70
-
-
0042859750
-
Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells
-
Smith MF, Mitchell A, Li GL, et al. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells. J Biol Chem 2003; 278(35): 32552-60.
-
(2003)
J Biol Chem
, vol.278
, Issue.35
, pp. 32552-32560
-
-
Smith, M.F.1
Mitchell, A.2
Li, G.L.3
-
71
-
-
5044240576
-
Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4
-
Mandell L, Moran AP, Cocchiarella A, et al. Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4. Infect immun 2004; 72(11): 6446-54.
-
(2004)
Infect immun
, vol.72
, Issue.11
, pp. 6446-6454
-
-
Mandell, L.1
Moran, A.P.2
Cocchiarella, A.3
-
72
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004; 118(3): 285-96.
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
74
-
-
0032528178
-
Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas
-
Wilson KT, Fu S, Ramanujam KS, et al. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas. Cancer Res 1998; 58(14): 2929-34.
-
(1998)
Cancer Res
, vol.58
, Issue.14
, pp. 2929-2934
-
-
Wilson, K.T.1
Fu, S.2
Ramanujam, K.S.3
-
75
-
-
84898670689
-
Functional expression of TLR9 in esophageal cancer
-
Zhang YL, Wang QY, Ma AL, et al. Functional expression of TLR9 in esophageal cancer. Oncol Reports 2014; 31(5): 2298-304.
-
(2014)
Oncol Reports
, vol.31
, Issue.5
, pp. 2298-2304
-
-
Zhang, Y.L.1
Wang, Q.Y.2
Ma, A.L.3
-
76
-
-
84892476369
-
Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis
-
Song X, Gao H, Lin Y, et al. Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis. Immunity 2014; 40(1): 140-52.
-
(2014)
Immunity
, vol.40
, Issue.1
, pp. 140-152
-
-
Song, X.1
Gao, H.2
Lin, Y.3
-
77
-
-
84900397337
-
Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis
-
Kennedy CL, Najdovska M, Tye H, et al. Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis. Oncogene 2014; 33(19): 2540-6.
-
(2014)
Oncogene
, vol.33
, Issue.19
, pp. 2540-2546
-
-
Kennedy, C.L.1
Najdovska, M.2
Tye, H.3
-
78
-
-
84867605321
-
STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation
-
Tye H, Kennedy CL, Najdovska M, et al. STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation. Cancer Cell 2012; 22(4): 466-78.
-
(2012)
Cancer Cell
, vol.22
, Issue.4
, pp. 466-478
-
-
Tye, H.1
Kennedy, C.L.2
Najdovska, M.3
-
79
-
-
84860830073
-
Induction of microRNA- 155 is TLR- and type IV secretion system-dependent in macrophages and inhibits DNA-damage induced apoptosis
-
Koch M, Mollenkopf HJ, Klemm U, et al. Induction of microRNA- 155 is TLR- and type IV secretion system-dependent in macrophages and inhibits DNA-damage induced apoptosis. Proc Natl Acad Sci USA 2012; 109(19): E1153-62.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.19
, pp. 1153-1162
-
-
Koch, M.1
Mollenkopf, H.J.2
Klemm, U.3
-
80
-
-
20044392148
-
Toll-like receptor 2- mediated gene expression in epithelial cells during Helicobacter pylori infection
-
Ding SZ, Torok AM, Smith MF, Jr., et al. Toll-like receptor 2- mediated gene expression in epithelial cells during Helicobacter pylori infection. Helicobacter 2005; 10(3): 193-204.
-
(2005)
Helicobacter
, vol.10
, Issue.3
, pp. 193-204
-
-
Ding, S.Z.1
Torok, A.M.2
Smith, M.F.3
-
81
-
-
84868613705
-
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
-
Grivennikov SI, Wang K, Mucida D, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012; 491(7423): 254-8.
-
(2012)
Nature
, vol.491
, Issue.7423
, pp. 254-258
-
-
Grivennikov, S.I.1
Wang, K.2
Mucida, D.3
-
82
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
Caramalho I, Lopes-Carvalho T, Ostler D, et al. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 2003; 197(4): 403-11.
-
(2003)
J Exp Med
, vol.197
, Issue.4
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
-
83
-
-
29144534608
-
Human CD4(+) T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4(+)CD25(+) T regulatory cells
-
Crellin NK, Garcia RV, Hadisfar O, et al. Human CD4(+) T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4(+)CD25(+) T regulatory cells. J Immunol 2005; 175(12): 8051-9.
-
(2005)
J Immunol
, vol.175
, Issue.12
, pp. 8051-8059
-
-
Crellin, N.K.1
Garcia, R.V.2
Hadisfar, O.3
-
84
-
-
10344233176
-
Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells
-
Kubo T, Hatton RD, Oliver J, et al. Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells. J Immunol 2004; 173(12): 7249-58.
-
(2004)
J Immunol
, vol.173
, Issue.12
, pp. 7249-7258
-
-
Kubo, T.1
Hatton, R.D.2
Oliver, J.3
-
85
-
-
20444432334
-
Toll-like receptors on tumor cells facilitate evasion of immune surveillance
-
Huang B, Zhao J, Li H, et al. Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res 2005; 65(12): 5009-14.
-
(2005)
Cancer Res
, vol.65
, Issue.12
, pp. 5009-5014
-
-
Huang, B.1
Zhao, J.2
Li, H.3
-
86
-
-
84902548704
-
Toll-like receptors: Role in inflammation and therapeutic potential
-
Kay E, Scotland RS, Whiteford JR. Toll-like receptors: Role in inflammation and therapeutic potential. Biofactors 2014; 40(3): 284-94.
-
(2014)
Biofactors
, vol.40
, Issue.3
, pp. 284-294
-
-
Kay, E.1
Scotland, R.S.2
Whiteford, J.R.3
-
87
-
-
43349087755
-
Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling
-
Farhat K, Riekenberg S, Heine H, et al. Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling. J Leukoc Biol 2008; 83(3): 692- 701.
-
(2008)
J Leukoc Biol
, vol.83
, Issue.3
, pp. 692-701
-
-
Farhat, K.1
Riekenberg, S.2
Heine, H.3
-
88
-
-
34548608447
-
Crystal structure of the TLR1- TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
-
Jin MS, Kim SE, Heo JY, et al. Crystal structure of the TLR1- TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 2007; 130(6): 1071-82.
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
-
89
-
-
0141768248
-
Importance of extra- and intracellular domains of TLR1 and TLR2 in NF kappa B signaling
-
Sandor F, Latz E, Re F, et al. Importance of extra- and intracellular domains of TLR1 and TLR2 in NF kappa B signaling. J Cell Biol 2003; 162(6): 1099-110.
-
(2003)
J Cell Biol
, vol.162
, Issue.6
, pp. 1099-1110
-
-
Sandor, F.1
Latz, E.2
Re, F.3
-
90
-
-
0037177825
-
Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
-
Asea A, Rehli M, Kabingu E, et al. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 2002; 277(17): 15028-34.
-
(2002)
J Biol Chem
, vol.277
, Issue.17
, pp. 15028-15034
-
-
Asea, A.1
Rehli, M.2
Kabingu, E.3
-
91
-
-
84905127342
-
Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer
-
Castano-Rodriguez N, Kaakoush NO, Pardo AL, et al. Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer. Hum Immunol 2014; 75(8): 808-15.
-
(2014)
Hum Immunol
, vol.75
, Issue.8
, pp. 808-815
-
-
Castano-Rodriguez, N.1
Kaakoush, N.O.2
Pardo, A.L.3
-
92
-
-
0037083638
-
Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent
-
Massari P, Henneke P, Ho Y, et al. Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent. J Immunol 2002; 168(4): 1533-7.
-
(2002)
J Immunol
, vol.168
, Issue.4
, pp. 1533-1537
-
-
Massari, P.1
Henneke, P.2
Ho, Y.3
-
93
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
-
Ozinsky A, Underhill DM, Fontenot JD, et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc Natl Acad Sci USA 2000; 97(25): 13766-71.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.25
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
-
94
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park JS, Svetkauskaite D, He Q, et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004; 279(9): 7370-7.
-
(2004)
J Biol Chem
, vol.279
, Issue.9
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
-
95
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
-
Schwandner R, Dziarski R, Wesche H, et al. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem 1999; 274(25): 17406-9.
-
(1999)
J Biol Chem
, vol.274
, Issue.25
, pp. 17406-17409
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
-
96
-
-
84859920121
-
Toll-like receptor genes and their association with colon and rectal cancer development and prognosis
-
Slattery ML, Herrick JS, Bondurant KL, et al. Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. Int J Cancer 2012; 130(12): 2974-80.
-
(2012)
Int J Cancer
, vol.130
, Issue.12
, pp. 2974-2980
-
-
Slattery, M.L.1
Herrick, J.S.2
Bondurant, K.L.3
-
97
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi O, Hoshino K, Kawai T, et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 1999; 11(4): 443-51.
-
(1999)
Immunity
, vol.11
, Issue.4
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
-
98
-
-
84872372112
-
A frequent Toll-like receptor 1 gene polymorphism affects NK- and T-cell IFN-gamma production and is associated with Helicobacter pylori-induced gastric disease
-
Yang CA, Scheibenbogen C, Bauer S, et al. A frequent Toll-like receptor 1 gene polymorphism affects NK- and T-cell IFN-gamma production and is associated with Helicobacter pylori-induced gastric disease. Helicobacter 2013; 18(1): 13-21.
-
(2013)
Helicobacter
, vol.18
, Issue.1
, pp. 13-21
-
-
Yang, C.A.1
Scheibenbogen, C.2
Bauer, S.3
-
99
-
-
0035909372
-
Recognition of double- stranded RNA and activation of NF-kappa B by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, et al. Recognition of double- stranded RNA and activation of NF-kappa B by Toll-like receptor 3. Nature 2001; 413(6857): 732-8.
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
-
100
-
-
84894469067
-
Clinical significance of toll-like receptor 3, 4, and 9 in gastric cancer
-
Fernandez-Garcia B, Eiro N, Gonzalez-Reyes S, et al. Clinical significance of toll-like receptor 3, 4, and 9 in gastric cancer. J Immunother 2014; 37(2): 77-83.
-
(2014)
J Immunother
, vol.37
, Issue.2
, pp. 77-83
-
-
Fernandez-Garcia, B.1
Eiro, N.2
Gonzalez-Reyes, S.3
-
101
-
-
84895639283
-
The expression and function of Toll-like receptors 3 and 9 in human colon carcinoma
-
Nojiri K, Sugimoto K, Shiraki K, et al. The expression and function of Toll-like receptors 3 and 9 in human colon carcinoma. Oncol Rep 2013; 29(5): 1737-43.
-
(2013)
Oncol Rep
, vol.29
, Issue.5
, pp. 1737-1743
-
-
Nojiri, K.1
Sugimoto, K.2
Shiraki, K.3
-
102
-
-
84875653192
-
The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: A case-control study and meta-analysis
-
Castano-Rodriguez N, Kaakoush NO, Goh KL, et al. The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: a case-control study and meta-analysis. PLoS One 2013; 8(4): e60327.
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Castano-Rodriguez, N.1
Kaakoush, N.O.2
Goh, K.L.3
-
103
-
-
0034723186
-
Mouse toll-like receptor 4 center dot MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by taxol
-
Kawasaki K, Akashi S, Shimazu R, et al. Mouse toll-like receptor 4 center dot MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by taxol. J Biol Chem 2000; 275(4): 2251-4.
-
(2000)
J Biol Chem
, vol.275
, Issue.4
, pp. 2251-2254
-
-
Kawasaki, K.1
Akashi, S.2
Shimazu, R.3
-
104
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones EA, Popova L, Kwinn L, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000; 1(5): 398-401.
-
(2000)
Nat Immunol
, vol.1
, Issue.5
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
-
105
-
-
0034650427
-
Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
-
Ohashi K, Burkart V, Flohe S, et al. Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000; 164(2): 558-61.
-
(2000)
J Immunol
, vol.164
, Issue.2
, pp. 558-561
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
-
106
-
-
0035971217
-
The extra domain A of fibronectin activates toll-like receptor 4
-
Okamura Y, Watari M, Jerud ES, et al. The extra domain A of fibronectin activates toll-like receptor 4. J Biol Chem 2001; 276(13): 10229-33.
-
(2001)
J Biol Chem
, vol.276
, Issue.13
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
-
107
-
-
6344241296
-
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosama cruzi glycoinositolphospholipids and higher resistance to infection with T-cruzi
-
Oliveira AC, Peixoto JR, de Arruda LB, et al. Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosama cruzi glycoinositolphospholipids and higher resistance to infection with T-cruzi. J Immunol 2004; 173(9): 5688-96.
-
(2004)
J Immunol
, vol.173
, Issue.9
, pp. 5688-5696
-
-
Oliveira, A.C.1
Peixoto, J.R.2
de Arruda, L.B.3
-
108
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He XL, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 1998; 282(5396): 2085-8.
-
(1998)
Science
, vol.282
, Issue.5396
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.L.2
Smirnova, I.3
-
109
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with toll-like receptor 4
-
Rassa JC, Meyers JL, Zhang YM, et al. Murine retroviruses activate B cells via interaction with toll-like receptor 4. Proc Natl Acad Sci USA 2002; 99(4): 2281-6.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.4
, pp. 2281-2286
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.M.3
-
110
-
-
0035800883
-
Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via Toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation
-
Sasu S, LaVerda D, Qureshi N, et al. Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via Toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation. Circ Res 2001; 89(3): 244-50.
-
(2001)
Circ Res
, vol.89
, Issue.3
, pp. 244-250
-
-
Sasu, S.1
LaVerda, D.2
Qureshi, N.3
-
111
-
-
0035451118
-
Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4
-
Smiley ST, King JA, Hancock WW. Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J Immunol 2001; 167(5): 2887-94.
-
(2001)
J Immunol
, vol.167
, Issue.5
, pp. 2887-2894
-
-
Smiley, S.T.1
King, J.A.2
Hancock, W.W.3
-
112
-
-
0036021109
-
Saccharomyces cerevisiaeand Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD14-and Toll-like receptor 4-dependent manner
-
Tada H, Nemoto E, Shimauchi H, et al. Saccharomyces cerevisiaeand Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD14-and Toll-like receptor 4-dependent manner. Microbiol Immunol 2002; 46(7): 503-12.
-
(2002)
Microbiol Immunol
, vol.46
, Issue.7
, pp. 503-512
-
-
Tada, H.1
Nemoto, E.2
Shimauchi, H.3
-
113
-
-
0037033364
-
Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4
-
Termeer C, Benedix F, Sleeman J, et al. Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 2002; 195(1): 99-111.
-
(2002)
J Exp Med
, vol.195
, Issue.1
, pp. 99-111
-
-
Termeer, C.1
Benedix, F.2
Sleeman, J.3
-
114
-
-
10344264453
-
Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway
-
Zhai Y, Shen XD, O'Connell R, et al. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol 2004; 173(12): 7115-9.
-
(2004)
J Immunol
, vol.173
, Issue.12
, pp. 7115-7119
-
-
Zhai, Y.1
Shen, X.D.2
O'Connell, R.3
-
115
-
-
84907818838
-
Association between TLR4 (+896A/G and+1196C/T) polymorphisms and gastric cancer risk: An updated meta-analysis
-
Zhou Q, Wang CC, Wang XF, et al. Association between TLR4 (+896A/G and+1196C/T) polymorphisms and gastric cancer risk: an updated meta-analysis. PLoS One 2014; 9(10): 11.
-
(2014)
PLoS One
, vol.9
, Issue.10
, pp. 11
-
-
Zhou, Q.1
Wang, C.C.2
Wang, X.F.3
-
116
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F, Smith KD, Ozinsky A, et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001; 410(6832): 1099-103.
-
(2001)
Nature
, vol.410
, Issue.6832
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
-
117
-
-
83055163894
-
Genetic variants of toll-like receptor 2 and 5, helicobacter pylori infection, and risk of gastric cancer and its precursors in a chinese population
-
Zeng HM, Pan KF, Zhang Y, et al. Genetic variants of toll-like receptor 2 and 5, helicobacter pylori infection, and risk of gastric cancer and its precursors in a chinese population. Cancer Epidemiol Biomarkers Prevent 2011; 20(12): 2594-602.
-
(2011)
Cancer Epidemiol Biomarkers Prevent
, vol.20
, Issue.12
, pp. 2594-2602
-
-
Zeng, H.M.1
Pan, K.F.2
Zhang, Y.3
-
118
-
-
77957196909
-
Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression
-
Grimm M, Kim M, Rosenwald A, et al. Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression. Eur J Cancer 2010; 46(15): 2849-57.
-
(2010)
Eur J Cancer
, vol.46
, Issue.15
, pp. 2849-2857
-
-
Grimm, M.1
Kim, M.2
Rosenwald, A.3
-
119
-
-
0242391997
-
The toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
-
Heil F, Ahmad-Nejad P, Hemmi H, et al. The toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 2003; 33(11): 2987-97.
-
(2003)
Eur J Immunol
, vol.33
, Issue.11
, pp. 2987-2997
-
-
Heil, F.1
Ahmad-Nejad, P.2
Hemmi, H.3
-
120
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F, Hemmi H, Hochrein H, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004; 303(5663): 1526-9.
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
-
121
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O, et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002; 3(2): 196-200.
-
(2002)
Nat Immunol
, vol.3
, Issue.2
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
-
122
-
-
33750823681
-
Cutting edge: Activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides
-
Gorden KKB, Qiu XX, Binsfeld CCA, et al. Cutting edge: Activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides. J Immunol 2006; 177(10): 6584-7.
-
(2006)
J Immunol
, vol.177
, Issue.10
, pp. 6584-6587
-
-
Gorden, K.K.B.1
Qiu, X.X.2
Binsfeld, C.C.A.3
-
123
-
-
19944430901
-
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
-
Coban C, Ishii KJ, Kawai T, et al. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med 2005; 201(1): 19-25.
-
(2005)
J Exp Med
, vol.201
, Issue.1
, pp. 19-25
-
-
Coban, C.1
Ishii, K.J.2
Kawai, T.3
-
124
-
-
84880102029
-
Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: Clinico-pathogenic aspects
-
Furi I, Sipos F, Germann TM, et al. Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: clinico-pathogenic aspects. World J Gastroenterol 2013; 19(26): 4119-26.
-
(2013)
World J Gastroenterol
, vol.19
, Issue.26
, pp. 4119-4126
-
-
Furi, I.1
Sipos, F.2
Germann, T.M.3
-
125
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408(6813): 740-5.
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
126
-
-
0034777579
-
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
-
Krug A, Towarowski A, Britsch S, et al. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur J Immunol 2001; 31(10): 3026- 37.
-
(2001)
Eur J Immunol
, vol.31
, Issue.10
, pp. 37-3026
-
-
Krug, A.1
Towarowski, A.2
Britsch, S.3
-
127
-
-
84912079413
-
Helicobacter pylori regulates TLR4 and TLR9 during gastric carcinogenesis
-
Wang TR, Peng JC, Qiao YQ, et al. Helicobacter pylori regulates TLR4 and TLR9 during gastric carcinogenesis. Int J Clin Exp Pathol 2014; 7(10): 6950-5.
-
(2014)
Int J Clin Exp Pathol
, vol.7
, Issue.10
, pp. 6950-6955
-
-
Wang, T.R.1
Peng, J.C.2
Qiao, Y.Q.3
-
128
-
-
25644451261
-
Flagellin enhances NK cell proliferation and, activation directly and through dendritic cell- NK cell interactions
-
Tsujimoto H, Uchida T, Efron PA, et al. Flagellin enhances NK cell proliferation and, activation directly and through dendritic cell- NK cell interactions. J Leukoc Biol 2005; 78(4): 888-97.
-
(2005)
J Leukoc Biol
, vol.78
, Issue.4
, pp. 888-897
-
-
Tsujimoto, H.1
Uchida, T.2
Efron, P.A.3
-
129
-
-
1542377424
-
A toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang DK, Zhang GL, Hayden MS, et al. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 2004; 303(5663): 1522-6.
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1522-1526
-
-
Zhang, D.K.1
Zhang, G.L.2
Hayden, M.S.3
|