Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with Cd40 ligand to induce high amounts of IL-12

European Journal of Immunology

Volumn 31, Issue 10, 2001, Pages 3026-3037

  Krug, Anne ^a   Towarowski, Andreas ^a   Britsch, Stefanie ^a   Rothenfusser, Simon ^a   Hornung, Veit ^a   Bals, Robert ^a   Giese, Thomas ^b   Engelmann, Hartmut ^a   Endres, Stefan ^a   Krieg, Arthur M ^c,d,e   Hartmann, Gunther ^a,f  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF IOWA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e PFIZER INC   (United States)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cd40 ligand; CpG oligodeoxynucleotide; IL 12; Plasmacytoid dendritic cell; Th1

Indexed keywords

ALPHA INTERFERON; B7 ANTIGEN; CD123 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR7; DNA; GLYCOPROTEIN GP 39; GLYCOPROTEIN P 15095; INTERLEUKIN 12; INTERLEUKIN 3; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LYMPHOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OLIGODEOXYNUCLEOTIDE; PROTEIN P70; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CELL STIMULATION; CONTROLLED STUDY; CPG ISLAND; DENDRITIC CELL; HELPER CELL; HUMAN; HUMAN CELL; INCUBATION TIME; LYMPHOCYTE HOMING; LYMPHOCYTE PROLIFERATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PLASMACYTOSIS; POLARIZATION; PRIORITY JOURNAL; PROTEIN MOTIF; T LYMPHOCYTE; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELL MOVEMENT; CELLS, CULTURED; DENDRITIC CELLS; DINUCLEOSIDE PHOSPHATES; DROSOPHILA PROTEINS; DRUG SYNERGISM; HUMANS; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, CELL SURFACE; RECEPTORS, CHEMOKINE; TH1 CELLS; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 0034777579     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(2001010)31:10<3026::AID-IMMU3026>3.0.CO;2-H     Document Type: Article

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