Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and toll-like receptor 4

Immunity

Volumn 41, Issue 2, 2014, Pages 296-310

  Venkatesh, Madhukumar ^a   Mukherjee, Subhajit ^a   Wang, Hongwei ^a   Li, Hao ^a   Sun, Katherine ^b   Benechet, Alexandre P ^c   Qiu, Zhijuan ^c   Maher, Leigh ^c   Redinbo, Matthew R ^d   Phillips, Robert S ^e   Fleet, James C ^f   Kortagere, Sandhya ^g   Mukherjee, Paromita ^a   Fasano, Alessio ^h   Le Ven, Jessica ⁱ   Nicholson, Jeremy K ⁱ   Dumas, Marc E ⁱ   Khanna, Kamal M ^c   Mani, Sridhar ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b MONTEFIORE MEDICAL CENTER   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^d University of North Carolina at Chapel Hill   (United States)

^e UNIVERSITY OF GEORGIA   (United States)

^f PURDUE UNIVERSITY   (United States)

^g DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

ⁱ IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE; INDOLE DERIVATIVE; INDOLEPROPIONIC ACID; MESSENGER RNA; PREGNANE X RECEPTOR; PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GASTROINTESTINAL TRACT FUNCTION; INTESTINE CELL; INTESTINE MUCOSA PERMEABILITY; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

ADHERENS JUNCTIONS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES; ANTIGENS, CD3; CACO-2 CELLS; CELL LINE; FEMALE; HEK293 CELLS; HUMANS; INDOLES; INDOMETHACIN; INFLAMMATION; INTESTINES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICROBIOTA; RECEPTORS, STEROID; REPERFUSION INJURY; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907597269     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.06.014     Document Type: Article

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