Saccharomyces cerevisiae- and Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD14- and Toll-like receptor 4-dependent manner

Microbiology and Immunology

Volumn 46, Issue 7, 2002, Pages 503-512

  Tada, Hiroyuki ^a   Nemoto, Eiji ^a   Shimauchi, Hidetoshi ^a   Watanabe, Toshihiko ^b   Mikami, Takeshi ^b   Matsumoto, Tatsuji ^b   Ohno, Naohito ^c   Tamura, Hiroshi ^d   Shibata, Ken Ichiro ^e   Akashi, Sachiko ^f   Miyake, Kensuke ^f   Sugawara, Shunji ^a   Takada, Haruhiko ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d SEIKAGAKU CORPORATION   (Japan)

^e HOKKAIDO UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

CD14; Fungal mannan; Monocyte; Toll like receptor 4

Indexed keywords

CD14 ANTIGEN; CYTOKINE; GLUCAN; LIPOPOLYSACCHARIDE BINDING PROTEIN; MANNAN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD14; MONOCLONAL ANTIBODY TLR2; MONOCLONAL ANTIBODY TLR4; POLYMYXIN B; POLYSACCHARIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ACUTE PHASE PROTEIN; BETA 1,3 GLUCAN; BETA GLUCAN; BETA-1,3-GLUCAN; CARRIER PROTEIN; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; ENDOTOXIN; LIPOPOLYSACCHARIDE-BINDING PROTEIN; MEMBRANE PROTEIN; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN; ZYMOSAN;

ARTICLE; CANDIDA ALBICANS; CARBOHYDRATE METABOLISM; CELL STIMULATION; CELL WALL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; INFLAMMATION; MONOCYTE; NONHUMAN; PROTEIN PURIFICATION; RECEPTOR BINDING; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; YEAST; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANTIGENS, CD14; CANDIDA ALBICANS; CARRIER PROTEINS; ENDOTOXINS; GLUCANS; HUMAN; MANNANS; MEMBRANE GLYCOPROTEINS; MONOCYTES; POLYMYXIN B; POLYSACCHARIDES; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TUMOR NECROSIS FACTOR; YEASTS; ZYMOSAN; ACUTE-PHASE PROTEINS; BETA-GLUCANS; DROSOPHILA PROTEINS; HUMANS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

CANDIDA; CANDIDA ALBICANS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0036021109     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2002.tb02727.x     Document Type: Article

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