메뉴 건너뛰기




Volumn 37, Issue 2, 2014, Pages 77-83

Clinical significance of toll-like receptor 3, 4, and 9 in gastric cancer

Author keywords

gastric carcinoma; prognosis; tissue arrays; Toll like receptors; tumor invasion

Indexed keywords

ADULT; AGED; AGED, 80 AND OVER; CARCINOGENESIS; CARCINOMA; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TUMOR MARKERS, BIOLOGICAL;

EID: 84894469067     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/CJI.0000000000000016     Document Type: Article
Times cited : (50)

References (52)
  • 1
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol. 2004;4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 2
    • 23744454577 scopus 로고    scopus 로고
    • TLR signalling and activation of IRFs: Revisiting old friends from the NF-kappa B pathway
    • Moynagh PN. TLR signalling and activation of IRFs: revisiting old friends from the NF-kappa B pathway. Trends Immunol. 2005;26:469-476.
    • (2005) Trends Immunol , vol.26 , pp. 469-476
    • Moynagh, P.N.1
  • 4
    • 16644366474 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare C, Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Microbes Infect. 2004;6:1382-1387.
    • (2004) Microbes Infect , vol.6 , pp. 1382-1387
    • Pasare, C.1    Medzhitov, R.2
  • 5
    • 0036293726 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger P. An innate sense of danger. Ann N Y Acad Sci. 2002;961:341-342.
    • (2002) Ann N y Acad Sci , vol.961 , pp. 341-342
    • Matzinger, P.1
  • 6
    • 78649552269 scopus 로고    scopus 로고
    • Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis
    • Gonzalez-Reyes S, Marin L, Gonzalez L, et al. Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis. BMC Cancer. 2010;10:665-673.
    • (2010) BMC Cancer , vol.10 , pp. 665-673
    • Gonzalez-Reyes, S.1    Marin, L.2    Gonzalez, L.3
  • 7
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappa B by Tolllike receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, et al. Recognition of double-stranded RNA and activation of NF-kappa B by Tolllike receptor 3. Nature. 2001;413:732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3
  • 8
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 9
    • 0035953543 scopus 로고    scopus 로고
    • The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
    • Hayashi F, Smith KD, Ozinsky A, et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 2001;410:1099-1103.
    • (2001) Nature , vol.410 , pp. 1099-1103
    • Hayashi, F.1    Smith, K.D.2    Ozinsky, A.3
  • 10
    • 67651113967 scopus 로고    scopus 로고
    • Increased expression of Tolllike receptors 4 and 9 in human lung cancer
    • Zhang YB, He FL, Fang M, et al. Increased expression of Tolllike receptors 4 and 9 in human lung cancer. Mol Biol Rep. 2009;36:1475-1481.
    • (2009) Mol Biol Rep , vol.36 , pp. 1475-1481
    • Zhang, Y.B.1    He, F.L.2    Fang, M.3
  • 12
    • 37849033136 scopus 로고    scopus 로고
    • Role of Toll-like receptors in gastrointestinal malignancies
    • Fukata M, Abreu MT. Role of Toll-like receptors in gastrointestinal malignancies. Oncogene. 2008;27:234-243.
    • (2008) Oncogene , vol.27 , pp. 234-243
    • Fukata, M.1    Abreu, M.T.2
  • 13
    • 33947304959 scopus 로고    scopus 로고
    • A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors
    • Hold GL, Rabkin CS, Chow WH, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology. 2007;132:905-912.
    • (2007) Gastroenterology. , vol.132 , pp. 905-912
    • Hold, G.L.1    Rabkin, C.S.2    Chow, W.H.3
  • 14
    • 36549082403 scopus 로고    scopus 로고
    • Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
    • Fukata M, Chen A, Vamadevan AS, et al. Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology. 2007;133:1869-1881.
    • (2007) Gastroenterology , vol.133 , pp. 1869-1881
    • Fukata, M.1    Chen, A.2    Vamadevan, A.S.3
  • 15
    • 38649087921 scopus 로고    scopus 로고
    • Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis
    • Swann JB, Vesely MD, Silva A, et al. Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis. Proc Natl Acad Sci U S A. 2008; 105:652-656.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 652-656
    • Swann, J.B.1    Vesely, M.D.2    Silva, A.3
  • 16
    • 33748136551 scopus 로고    scopus 로고
    • Heterozygous Thr 135 Ala polymorphism at leucine-rich repeat (LRR) in genomic DNA of toll-like receptor 4 in patients with poorly-differentiated gastric adenocarcinomas
    • Ohara T, Morishita T, Suzuki H, et al. Heterozygous Thr 135 Ala polymorphism at leucine-rich repeat (LRR) in genomic DNA of toll-like receptor 4 in patients with poorly-differentiated gastric adenocarcinomas. Int J Mol Med. 2006;18:59-63.
    • (2006) Int J Mol Med , vol.18 , pp. 59-63
    • Ohara, T.1    Morishita, T.2    Suzuki, H.3
  • 17
    • 83055163894 scopus 로고    scopus 로고
    • Genetic variants of toll-like receptor 2 and 5, Helicobacter pylori infection, and risk of gastric cancer and its precursors in a Chinese population
    • Zeng HM, Pan KF, Zhang Y, et al. Genetic variants of toll-like receptor 2 and 5, Helicobacter pylori infection, and risk of gastric cancer and its precursors in a Chinese population. Cancer Epidemiol Biomarkers Prev. 2011;20:2594-2602.
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , pp. 2594-2602
    • Zeng, H.M.1    Pan, K.F.2    Zhang, Y.3
  • 18
    • 80052745459 scopus 로고    scopus 로고
    • Increased expression of toll-like receptors (TLR) 2, 4 and 5 in gastric dysplasia
    • Pimentel-Nunes P, Afonso L, Lopes P, et al. Increased expression of toll-like receptors (TLR) 2, 4 and 5 in gastric dysplasia. Pathol Oncol Res. 2011;17:677-683.
    • (2011) Pathol Oncol Res , vol.17 , pp. 677-683
    • Pimentel-Nunes, P.1    Afonso, L.2    Lopes, P.3
  • 19
    • 84872422199 scopus 로고    scopus 로고
    • Helicobacter pylori induces increased expression of Toll-like receptors and decreased Toll-interacting protein in gastric mucosa that persists throughout gastric carcinogenesis
    • Pimentel-Nunes P, Goncalves N, Boal-Carvalho I, et al. Helicobacter pylori induces increased expression of Toll-like receptors and decreased Toll-interacting protein in gastric mucosa that persists throughout gastric carcinogenesis. Helicobacter. 2013;18:22-32.
    • (2013) Helicobacter , vol.18 , pp. 22-32
    • Pimentel-Nunes, P.1    Goncalves, N.2    Boal-Carvalho, I.3
  • 20
    • 84867605321 scopus 로고    scopus 로고
    • STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation
    • Tye H, Kennedy CL, Najdovska M, et al. STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation. Cancer Cell. 2012;22: 466-478.
    • (2012) Cancer Cell , vol.22 , pp. 466-478
    • Tye, H.1    Kennedy, C.L.2    Najdovska, M.3
  • 21
    • 79151485605 scopus 로고    scopus 로고
    • Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence
    • Gonzalez-Reyes S, Fernandez JM, Gonzalez LO, et al. Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence. Cancer Immunol Immunother. 2011;60:217-226.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 217-226
    • Gonzalez-Reyes, S.1    Fernandez, J.M.2    Gonzalez, L.O.3
  • 22
    • 84872332945 scopus 로고    scopus 로고
    • Expression of TLR3, 4, 7 and 9 in cutaneous malignant melanoma: Relationship with clinicopathological characteristics and prognosis
    • Eiro N, Ovies C, Fernandez-Garcia B, et al. Expression of TLR3, 4, 7 and 9 in cutaneous malignant melanoma: relationship with clinicopathological characteristics and prognosis. Arch Dermatol Res. 2013;305:59-67.
    • (2013) Arch Dermatol Res , vol.305 , pp. 59-67
    • Eiro, N.1    Ovies, C.2    Fernandez-Garcia, B.3
  • 23
    • 84863981516 scopus 로고    scopus 로고
    • Study of the expression of toll-like receptors in different histological types of colorectal polyps and their relationship with colorectal cancer
    • Eiro N, Gonzalez L, Gonzalez LO, et al. Study of the expression of toll-like receptors in different histological types of colorectal polyps and their relationship with colorectal cancer. J Clin Immunol. 2012;32:848-854.
    • (2012) J Clin Immunol , vol.32 , pp. 848-854
    • Eiro, N.1    Gonzalez, L.2    Gonzalez, L.O.3
  • 25
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965;64:31-49.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 26
    • 1842435206 scopus 로고    scopus 로고
    • Significance of cytosolic hyaluronan levels in gastric cancer
    • Vizoso FJ, del Casar JM, Corte MD, et al. Significance of cytosolic hyaluronan levels in gastric cancer. Eur J Surg Oncol. 2004;30:318-324.
    • (2004) Eur J Surg Oncol , vol.30 , pp. 318-324
    • Vizoso, F.J.1    Del Casar, J.M.2    Corte, M.D.3
  • 27
    • 0036237888 scopus 로고    scopus 로고
    • Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarray
    • Parker RL, Huntsman DG, Lesack DW, et al. Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarray. Am J Clin Pathol. 2002;117:723-728.
    • (2002) Am J Clin Pathol , vol.117 , pp. 723-728
    • Parker, R.L.1    Huntsman, D.G.2    Lesack, D.W.3
  • 28
    • 79151485605 scopus 로고    scopus 로고
    • Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence
    • Gonzalez-Reyes S, Fernandez JM, Gonzalez LO, et al. Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence. Cancer Immunol Immunother. 2011;60:217-226.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 217-226
    • Gonzalez-Reyes, S.1    Fernandez, J.M.2    Gonzalez, L.O.3
  • 29
    • 44949129660 scopus 로고    scopus 로고
    • Androgen receptor expression in breast cancer: Relationship with clinicopathological characteristics of the tumors, prognosis, and expression of metalloproteases and their inhibitors
    • Gonzalez LO, Corte MD, Vazquez J, et al. Androgen receptor expression in breast cancer: relationship with clinicopathological characteristics of the tumors, prognosis, and expression of metalloproteases and their inhibitors. BMC Cancer. 2008;8: 149-158.
    • (2008) BMC Cancer , vol.8 , pp. 149-158
    • Gonzalez, L.O.1    Corte, M.D.2    Vazquez, J.3
  • 30
    • 70249099618 scopus 로고    scopus 로고
    • An approach for understanding the inflammation and cancer relationship
    • Costantini S, Capone F, Guerriero E, et al. An approach for understanding the inflammation and cancer relationship. Immunol Lett. 2009;126:91-92.
    • (2009) Immunol Lett , vol.126 , pp. 91-92
    • Costantini, S.1    Capone, F.2    Guerriero, E.3
  • 31
    • 70350664389 scopus 로고    scopus 로고
    • Cancer cells expressing tolllike receptors and the tumor microenvironment
    • Sato Y, Goto Y, Narita N, et al. Cancer cells expressing tolllike receptors and the tumor microenvironment. Cancer Microenviron. 2009;2(suppl 1):205-214.
    • (2009) Cancer Microenviron. , vol.2 , Issue.SUPPL. 1 , pp. 205-214
    • Sato, Y.1    Goto, Y.2    Narita, N.3
  • 32
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg. RA. The hallmarks of cancer. Cell. 2000;100:57-70.
    • (2000) Cell. , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 33
    • 37849035627 scopus 로고    scopus 로고
    • TLR signaling by tumor and immune cells: A double-edged sword
    • Huang B, Zhao J, Unkeless JC, et al. TLR signaling by tumor and immune cells: a double-edged sword. Oncogene. 2008;27:218-224.
    • (2008) Oncogene , vol.27 , pp. 218-224
    • Huang, B.1    Zhao, J.2    Unkeless, J.C.3
  • 34
    • 44649161808 scopus 로고    scopus 로고
    • Role of toll-like receptors in tissue repair and tumorigenesis
    • Rakoff-Nahoum S, Medzhitov R. Role of toll-like receptors in tissue repair and tumorigenesis. Biochemistry (Mosc). 2008;73: 555-561.
    • (2008) Biochemistry (Mosc) , vol.73 , pp. 555-561
    • Rakoff-Nahoum, S.1    Medzhitov, R.2
  • 35
    • 38349056713 scopus 로고    scopus 로고
    • Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4
    • Voelcker V, Gebhardt C, Averbeck M, et al. Hyaluronan fragments induce cytokine and metalloprotease upregulation in human melanoma cells in part by signalling via TLR4. Exp Dermatol. 2008;17:100-107.
    • (2008) Exp Dermatol , vol.17 , pp. 100-107
    • Voelcker, V.1    Gebhardt, C.2    Averbeck, M.3
  • 36
    • 33845581291 scopus 로고    scopus 로고
    • Toll-like receptor-9 expression induced by tape-stripping triggers on effective immune response with CpG-oligodeoxynucleotides
    • Inoue J, Aramaki Y. Toll-like receptor-9 expression induced by tape-stripping triggers on effective immune response with CpG- oligodeoxynucleotides. Vaccine. 2007;25:1007-1013.
    • (2007) Vaccine , vol.25 , pp. 1007-1013
    • Inoue, J.1    Aramaki, Y.2
  • 37
    • 84894504777 scopus 로고    scopus 로고
    • Expression and clinical significance of metalloproteases and their inhibitors in gastric cancer
    • In press
    • Gonzalez L, Aguirre A, EiroN, et al. Expression and clinical significance of metalloproteases and their inhibitors in gastric cancer. Hepatogastroenterology. 2013. [In press].
    • (2013) Hepatogastroenterology.
    • Gonzalez, L.1    Eiron, A.A.2
  • 38
    • 20144373185 scopus 로고    scopus 로고
    • Toll-like receptors TLR4, TLR5 and TLR9 on gastric carcinoma cells: An implication for interaction with Helicobacter pylori
    • Schmausser B, Andrulis M, Endrich S, et al. Toll-like receptors TLR4, TLR5 and TLR9 on gastric carcinoma cells: an implication for interaction with Helicobacter pylori. Int J Med Microbiol. 2005;295:179-185.
    • (2005) Int J Med Microbiol , vol.295 , pp. 179-185
    • Schmausser, B.1    Andrulis, M.2    Endrich, S.3
  • 39
    • 29144501209 scopus 로고    scopus 로고
    • Helicobacter pylori-Induced invasion and angiogenesis of gastric cells is mediated by cyclooxygenase-2 induction through TLR2/TLR9 and promoter regulation
    • Chang YJ, Wu MS, Lin JT, et al. Helicobacter pylori-Induced invasion and angiogenesis of gastric cells is mediated by cyclooxygenase-2 induction through TLR2/TLR9 and promoter regulation. J Immunol. 2005;175:8242-8252.
    • (2005) J Immunol , vol.175 , pp. 8242-8252
    • Chang, Y.J.1    Wu, M.S.2    Lin, J.T.3
  • 40
    • 33645755382 scopus 로고    scopus 로고
    • TLR3 can directly trigger apoptosis in human cancer cells
    • Salaun B, Coste I, Rissoan MC, et al. TLR3 can directly trigger apoptosis in human cancer cells. J Immunol. 2006;176: 4894-4901.
    • (2006) J Immunol , vol.176 , pp. 4894-4901
    • Salaun, B.1    Coste, I.2    Rissoan, M.C.3
  • 41
    • 72249091840 scopus 로고    scopus 로고
    • Toll-like receptors 3 and 7 agonists enhance tumor cell lysis by human gammadelta T cells
    • Shojaei H, Oberg HH, Juricke M, et al. Toll-like receptors 3 and 7 agonists enhance tumor cell lysis by human gammadelta T cells. Cancer Res. 2009;69:8710-8717.
    • (2009) Cancer Res , vol.69 , pp. 8710-8717
    • Shojaei, H.1    Oberg, H.H.2    Juricke, M.3
  • 42
    • 52449093931 scopus 로고    scopus 로고
    • TLR3 and TLR4 expression in healthy and diseased human endometrium
    • Allhorn S, Boing C, Koch AA, et al. TLR3 and TLR4 expression in healthy and diseased human endometrium. Reprod Biol Endocrinol. 2008;6:40-50.
    • (2008) Reprod Biol Endocrinol , vol.6 , pp. 40-50
    • Allhorn, S.1    Boing, C.2    Koch, A.A.3
  • 43
    • 35348813788 scopus 로고    scopus 로고
    • Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma
    • Morikawa T, Sugiyama A, Kume H, et al. Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma. Clin Cancer Res. 2007;13:5703-5709.
    • (2007) Clin Cancer Res , vol.13 , pp. 5703-5709
    • Morikawa, T.1    Sugiyama, A.2    Kume, H.3
  • 44
    • 77950787070 scopus 로고    scopus 로고
    • Toll-like receptor 3-mediated suppression of TRAMP prostate cancer shows the critical role of type i interferons in tumor immune surveillance
    • Chin AI, Miyahira AK, Covarrubias A, et al. Toll-like receptor 3-mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance. Cancer Res. 2010;70:2595-2603.
    • (2010) Cancer Res , vol.70 , pp. 2595-2603
    • Chin, A.I.1    Miyahira, A.K.2    Covarrubias, A.3
  • 45
    • 85027941724 scopus 로고    scopus 로고
    • Toll-like receptor 3: Implications for proinflammatory microenvironment in human breast cancer
    • Amarante MK, de Oliveira KB, Guembarovski RL, et al. Toll-like receptor 3: implications for proinflammatory microenvironment in human breast cancer. Mol Biol Rep. 2012;39: 11087-11092.
    • (2012) Mol Biol Rep , vol.39 , pp. 11087-11092
    • Amarante, M.K.1    De Oliveira, K.B.2    Guembarovski, R.L.3
  • 46
    • 1942521223 scopus 로고    scopus 로고
    • Does Toll-like receptor 3 play a biological role in virus infections?
    • Edelmann KH, Richardson-Burns S, Alexopoulou L, et al. Does Toll-like receptor 3 play a biological role in virus infections? Virology. 2004;322:231-238.
    • (2004) Virology , vol.322 , pp. 231-238
    • Edelmann, K.H.1    Richardson-Burns, S.2    Alexopoulou, L.3
  • 47
    • 0141923686 scopus 로고    scopus 로고
    • Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirusand HIV-1-specific T cell responses
    • Lore K, Betts MR, Brenchley JM, et al. Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirusand HIV-1-specific T cell responses. J Immunol. 2003;171: 4320-4328.
    • (2003) J Immunol , vol.171 , pp. 4320-4328
    • Lore, K.1    Betts, M.R.2    Brenchley, J.M.3
  • 48
    • 72649102955 scopus 로고    scopus 로고
    • Attenuation of the influenza virus sickness behavior in mice deficient in Toll-like receptor 3
    • Majde JA, Kapas L, Bohnet SG, et al. Attenuation of the influenza virus sickness behavior in mice deficient in Toll-like receptor 3. Brain Behav Immun. 2010;24:306-315.
    • (2010) Brain Behav Immun , vol.24 , pp. 306-315
    • Majde, J.A.1    Kapas, L.2    Bohnet, S.G.3
  • 49
    • 67649979735 scopus 로고    scopus 로고
    • TLR3 gene polymorphisms and liver disease manifestations in chronic hepatitis C
    • Askar E, Bregadze R, Mertens J, et al. TLR3 gene polymorphisms and liver disease manifestations in chronic hepatitis C. J Med Virol. 2009;81:1204-1211.
    • (2009) J Med Virol , vol.81 , pp. 1204-1211
    • Askar, E.1    Bregadze, R.2    Mertens, J.3
  • 50
    • 33645017584 scopus 로고    scopus 로고
    • Rotavirus doublestranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells
    • Sato A, Iizuka M, Nakagomi O, et al. Rotavirus doublestranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells. J Gastroenterol Hepatol. 2006; 21:521-530.
    • (2006) J Gastroenterol Hepatol. , vol.21 , pp. 521-530
    • Sato, A.1    Iizuka, M.2    Nakagomi, O.3
  • 51
    • 0029146243 scopus 로고
    • Polyadenylicpolyuridylic acid enhances the natural cell-mediated cytotoxicity in patients with breast cancer undergoing mastectomy
    • Khan AL, Richardson S, Drew J, et al. Polyadenylicpolyuridylic acid enhances the natural cell-mediated cytotoxicity in patients with breast cancer undergoing mastectomy. Surgery. 1995;118:531-538.
    • (1995) Surgery , vol.118 , pp. 531-538
    • Khan, A.L.1    Richardson, S.2    Drew, J.3
  • 52
    • 0019086263 scopus 로고
    • Adjuvant immunotherapy using polyadenylic acid and polyuridylic acid (Poly A., Poly U.) in operable carcinoma of the breast (author's transl)
    • Lacour F, Lacour J, Spira A, et al. Adjuvant immunotherapy using polyadenylic acid and polyuridylic acid (Poly A., Poly U.) in operable carcinoma of the breast (author's transl). Chirurgie. 1980;106:737-743.
    • (1980) Chirurgie , vol.106 , pp. 737-743
    • Lacour, F.1    Lacour, J.2    Spira, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.