Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 2, 1997, Pages 657-662

  Coffey, Robert J ^a,b,c,e   Hawkey, Chris J ^a,b,c   Damstrup, Lars ^a,b,c   Graves Deal, Ramona ^a,b,c   Daniel, Vincent C ^a,b   Dempsey, Peter J ^a,b,c   Chinery, Rebecca ^a,b,c   Kirkland, Susan C ^d   Dubois, Raymond N ^a,b,c   Jetton, Thomas L ^b   Morrow, Jason D ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; PROSTAGLANDIN DERIVATIVE;

ARTICLE; BASOLATERAL MEMBRANE; CANCER CELL CULTURE; COLON CANCER; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOGENESIS; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION;

CELL COMPARTMENTATION; CELL NUCLEUS; CELL POLARITY; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; GLYCOPROTEINS; GROWTH SUBSTANCES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; MEMBRANE PROTEINS; MITOSIS; NITROBENZENES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; PYRAZOLES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, NEOPLASM; SULFONAMIDES; SULINDAC; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR CELLS, CULTURED;

EID: 12644261426     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.2.657     Document Type: Article

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