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Volumn , Issue , 2007, Pages 1219-1250

Candidate anti-herpesviral drugs; mechanisms of action and resistance

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EID: 84929284077     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511545313.069     Document Type: Chapter
Times cited : (8)

References (185)
  • 1
    • 0025950195 scopus 로고
    • Antiviral activity against VZV and HSV type 1 and type 2 of the (+) and (?) enan-tiomers of (R, S)-9-[4-hydroxy-2-(hydroxymethyl) butyl] gua-nine, in comparison to other closely related acyclic nucleo-sides
    • Abele, G., Cox, S., Bergman, S. et al. (1991). Antiviral activity against VZV and HSV type 1 and type 2 of the (+) and (?) enan-tiomers of (R, S)-9-[4-hydroxy-2-(hydroxymethyl) butyl] gua-nine, in comparison to other closely related acyclic nucleo-sides. Antivir. Chem. Chemother., 2, 163-169.
    • (1991) Antivir. Chem. Chemother , vol.2 , pp. 163-169
    • Abele, G.1    Cox, S.2    Bergman, S.3
  • 2
    • 0035136709 scopus 로고    scopus 로고
    • Murine cytomegalovirus open reading frame M27 plays an important role in growth and virulence in mice
    • Abenes, G., Lee, M., Haghjoo, E., Tong, T., Zhan, X., and Liu, F. (2001). Murine cytomegalovirus open reading frame M27 plays an important role in growth and virulence in mice. J. Virol., 75, 1697-1707.
    • (2001) J. Virol , vol.75 , pp. 1697-1707
    • Abenes, G.1    Lee, M.2    Haghjoo, E.3    Tong, T.4    Zhan, X.5    Liu, F.6
  • 3
    • 0036310661 scopus 로고    scopus 로고
    • Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases
    • Ablashi, D. V., Chatlynne, L. G., Whitman, J. E., Jr., and Cesarman, E. (2002). Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases. Clin. Microbiol. Rev., 15, 439-464.
    • (2002) Clin. Microbiol. Rev , vol.15 , pp. 439-464
    • Ablashi, D.V.1    Chatlynne, L.G.2    Whitman, J.E.3    Cesarman, E.4
  • 4
    • 0036144084 scopus 로고    scopus 로고
    • The antiviral agent 5-chloro-1,3-dihydroxyacridone interferes with assembly and maturation of herpes simplex virus
    • Akanitapichat, P. and Bastow, K. F. (2002). The antiviral agent 5-chloro-1,3-dihydroxyacridone interferes with assembly and maturation of herpes simplex virus. Antiviral Res., 53, 113-126.
    • (2002) Antiviral Res , vol.53 , pp. 113-126
    • Akanitapichat, P.1    Bastow, K.F.2
  • 5
    • 0034012992 scopus 로고    scopus 로고
    • Dihydroxyacridone derivatives as inhibitors of herpes virus replication
    • Akanitapichat, P., Lowden, C. T., and Bastow, K. F. (2000).1,3-dihydroxyacridone derivatives as inhibitors of herpes virus replication. Antiviral Res., 45, 123-134.
    • (2000) Antiviral Res , vol.45 , pp. 123-134
    • Akanitapichat, P.1    Lowden, C.T.2    Bastow, K.F.3
  • 6
    • 0037333556 scopus 로고    scopus 로고
    • Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-(14)C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism
    • Aldern, K. A., Ciesla, S. L., Winegarden, K. L., and Hostetler, K. Y. (2003). Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-(14)C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism. Mol. Pharmacol., 63, 678-681.
    • (2003) Mol. Pharmacol , vol.63 , pp. 678-681
    • Aldern, K.A.1    Ciesla, S.L.2    Winegarden, K.L.3    Hostetler, K.Y.4
  • 7
    • 3142781225 scopus 로고    scopus 로고
    • Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
    • Arkin, M. R. and Wells, J. A. (2004). Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream. Nat. Rev. Drug Discov., 3, 301-317.
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 301-317
    • Arkin, M.R.1    Wells, J.A.2
  • 9
    • 13044256383 scopus 로고    scopus 로고
    • A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
    • Baba, M., Nishimura, O., Kanzaki, N. et al. (1999). A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc. Natl Acad Sci. USA, 96, 5698-5703.
    • (1999) Proc. Natl Acad Sci. USA , vol.96 , pp. 5698-5703
    • Baba, M.1    Nishimura, O.2    Kanzaki, N.3
  • 10
    • 0037244124 scopus 로고    scopus 로고
    • Herpes simplex virus resistance to acyclovir and pen-ciclovir after two decades of antiviral therapy
    • Bacon, T. H., Levin, M. J., Leary, J. J., Sarisky, R. T., and Sutton, D. (2003). Herpes simplex virus resistance to acyclovir and pen-ciclovir after two decades of antiviral therapy. Clin. Microbiol. Rev., 16, 114-128.
    • (2003) Clin. Microbiol. Rev , vol.16 , pp. 114-128
    • Bacon, T.H.1    Levin, M.J.2    Leary, J.J.3    Sarisky, R.T.4    Sutton, D.5
  • 11
    • 0037119463 scopus 로고    scopus 로고
    • Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase
    • Baek, M. C., Krosky, P. M., He, Z., and Coen, D. M. (2002). Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase. Impor-tance of the P+5 position. J. Biol. Chem., 277, 29593-29599.
    • (2002) Impor-tance of the P+5 position. J. Biol. Chem , vol.277 , pp. 29593-29599
    • Baek, M.C.1    Krosky, P.M.2    He, Z.3    Coen, D.M.4
  • 12
    • 0035996085 scopus 로고    scopus 로고
    • Bicyclic pyrimidine nucle-oside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication
    • Balzarini, J. and McGuigan, C. (2002). Bicyclic pyrimidine nucle-oside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication. J. Antimicrob. Chemother., 50, 5-9.
    • (2002) J. Antimicrob. Chemother , vol.50 , pp. 5-9
    • Balzarini, J.1    Mc Guigan, C.2
  • 13
    • 0036236787 scopus 로고    scopus 로고
    • Lack of suscepti-bility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase
    • Balzarini, J., Sienaert, R., Liekens, S. et al. (2002). Lack of suscepti-bility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase. Mol. Pharmacol., 61, 1140-1145.
    • (2002) Mol. Pharmacol , vol.61 , pp. 1140-1145
    • Balzarini, J.1    Sienaert, R.2    Liekens, S.3
  • 14
    • 33645401301 scopus 로고    scopus 로고
    • Synthe-sis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirusandorthopoxviruses
    • Beadle, J. R., Wan, W.B., Ciesla, S. L. et al. (2006). Synthe-sis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirusandorthopoxviruses. J. Med.Chem., 49, 2010-2015.
    • (2006) J. Med.Chem , vol.49 , pp. 2010-2015
    • Beadle, J.R.1    Wan, W.B.2    Ciesla, S.L.3
  • 15
    • 0036239144 scopus 로고    scopus 로고
    • DNA cleavage and packaging proteins encoded by genes U(L)28, U(L)15, and U(L)33 of herpes simplex virus type 1 form a complex in infected cells
    • Beard, P. M., Taus, N. S., and Baines, J. D. (2002). DNA cleavage and packaging proteins encoded by genes U(L)28, U(L)15, and U(L)33 of herpes simplex virus type 1 form a complex in infected cells. J. Virol., 76, 4785-4791.
    • (2002) J. Virol , vol.76 , pp. 4785-4791
    • Beard, P.M.1    Taus, N.S.2    Baines, J.D.3
  • 16
    • 0035869132 scopus 로고    scopus 로고
    • Daily or weekly therapy with resiquimod (R-848) reduces gen-ital recurrences in herpes simplex virus-infected guinea pigs during and after treatment
    • Bernstein, D. I., Harrison, C. J., Tomai, M. A., and Miller, R. L. (2001). Daily or weekly therapy with resiquimod (R-848) reduces gen-ital recurrences in herpes simplex virus-infected guinea pigs during and after treatment. J. Infect. Dis., 183, 844-849.
    • (2001) J. Infect. Dis , vol.183 , pp. 844-849
    • Bernstein, D.I.1    Harrison, C.J.2    Tomai, M.A.3    Miller, R.L.4
  • 17
    • 0036093580 scopus 로고    scopus 로고
    • Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293
    • Betz, U. A., Fischer, R., Kleymann, G., Hendrix, M., and Rubsamen-Waigmann, H. (2002). Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293. Antimicrob. Agents Chemother., 46, 1766-1772.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 1766-1772
    • Betz, U.A.1    Fischer, R.2    Kleymann, G.3    Hendrix, M.4    Rubsamen-Waigmann, H.5
  • 18
    • 2942574415 scopus 로고    scopus 로고
    • Oral activity of ether lipid ester prodrugs of cido-fovir against experimental human cytomegalovirus infection
    • Bidanset, D. J., Beadle, J. R., Wan, W. B., Hostetler, K. Y., and Kern, E. R. (2004). Oral activity of ether lipid ester prodrugs of cido-fovir against experimental human cytomegalovirus infection. J. Infect. Dis., 190, 499-503.
    • (2004) J. Infect. Dis , vol.190 , pp. 499-503
    • Bidanset, D.J.1    Beadle, J.R.2    Wan, W.B.3    Hostetler, K.Y.4    Kern, E.R.5
  • 19
    • 0035991720 scopus 로고    scopus 로고
    • Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action
    • Biron, K. K., Harvey, R. J., Chamberlain, S. C. et al. (2002). Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action. Antimicrob.Agents Chemother., 46, 2365-2372.
    • (2002) Antimicrob.Agents Chemother , vol.46 , pp. 2365-2372
    • Biron, K.K.1    Harvey, R.J.2    Chamberlain, S.C.3
  • 20
    • 0031936307 scopus 로고    scopus 로고
    • The gene product of human cytomegalovirus open reading frame UL56 binds the pac motif and has specific nuclease activity
    • Bogner, E., Radsak, K., and Stinski, M. F. (1998). The gene product of human cytomegalovirus open reading frame UL56 binds the pac motif and has specific nuclease activity. J. Virol., 72, 2259-2264.
    • (1998) J. Virol , vol.72 , pp. 2259-2264
    • Bogner, E.1    Radsak, K.2    Stinski, M.F.3
  • 21
    • 0036207969 scopus 로고    scopus 로고
    • Human cytomegalovirus terminase as a target for antiviral chemotherapy
    • Bogner, E. (2002). Human cytomegalovirus terminase as a target for antiviral chemotherapy. Rev. Med. Virol., 12, 115-127.
    • (2002) Rev. Med. Virol , vol.12 , pp. 115-127
    • Bogner, E.1
  • 22
    • 21744445760 scopus 로고    scopus 로고
    • Design of translactam HCMV protease inhibitors as potent antivirals
    • Borthwick, A. D. (2005). Design of translactam HCMV protease inhibitors as potent antivirals. Med. Res. Rev., 25, 427-452.
    • (2005) Med. Res. Rev , vol.25 , pp. 427-452
    • Borthwick, A.D.1
  • 23
    • 0032539506 scopus 로고    scopus 로고
    • Design and synthesis of monocyclic beta-lactams as mechanism-based inhibitors of human cytomegalovirus protease
    • Borthwick, A. D., Weingarten, G., Haley, T. M. et al. (1998). Design and synthesis of monocyclic beta-lactams as mechanism-based inhibitors of human cytomegalovirus protease. Bioorg. Med. Chem. Lett., 8, 365-370.
    • (1998) Bioorg. Med. Chem. Lett , vol.8 , pp. 365-370
    • Borthwick, A.D.1    Weingarten, G.2    Haley, T.M.3
  • 25
    • 0034954515 scopus 로고    scopus 로고
    • Identification and characterization of a benzothio-phene inhibitor of herpes simplex virus type 1 replication which acts at the immediate early stage of infection
    • Boulware, S. L., Bronstein, J. C., Nordby, E. C., and Weber, P. C. (2001). Identification and characterization of a benzothio-phene inhibitor of herpes simplex virus type 1 replication which acts at the immediate early stage of infection. Antivi-ral Res., 51, 111-125.
    • (2001) Antivi-ral Res , vol.51 , pp. 111-125
    • Boulware, S.L.1    Bronstein, J.C.2    Nordby, E.C.3    Weber, P.C.4
  • 26
    • 0034832724 scopus 로고    scopus 로고
    • In vitro metabolism and drug interaction poten-tial of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide)
    • Bournique, B., Lambert, N., Boukaiba, R., and Martinet, M. (2001). In vitro metabolism and drug interaction poten-tial of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide). Br. J. Clin. Pharmacol., 52, 53-63.
    • (2001) Br. J. Clin. Pharmacol , vol.52 , pp. 53-63
    • Bournique, B.1    Lambert, N.2    Boukaiba, R.3    Martinet, M.4
  • 27
    • 0027217643 scopus 로고
    • Compilation, alignment, and phylogenetic relationships of DNA polymerases
    • Braithwaite, D. K. and Ito, J. (1993). Compilation, alignment, and phylogenetic relationships of DNA polymerases. Nucl. Acids Res., 21, 787-802.
    • (1993) Nucl. Acids Res , vol.21 , pp. 787-802
    • Braithwaite, D.K.1    Ito, J.2
  • 28
    • 18344373269 scopus 로고    scopus 로고
    • Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses
    • Brideau, R. J., Knechtel, M. L., Huang, A. et al. (2002). Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses. Antiviral Res., 54, 19-28.
    • (2002) Antiviral Res , vol.54 , pp. 19-28
    • Brideau, R.J.1    Knechtel, M.L.2    Huang, A.3
  • 29
    • 0029125949 scopus 로고
    • Crystal structures of the thymidine kinase from herpes simplex virus type-1 in com-plex with deoxythymidine and ganciclovir
    • Brown, D. G., Visse, R., Sandhu, G. et al. (1995).Crystal structures of the thymidine kinase from herpes simplex virus type-1 in com-plex with deoxythymidine and ganciclovir. Nat. Struct. Biol., 2, 876-881.
    • (1995) Nat. Struct. Biol , vol.2 , pp. 876-881
    • Brown, D.G.1    Visse, R.2    Sandhu, G.3
  • 30
    • 0034855634 scopus 로고    scopus 로고
    • A novel non-nucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products
    • Buerger, I., Reefschlaeger, J., Bender, W. et al. (2001). A novel non-nucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products. J. Virol., 75, 9077-9086.
    • (2001) J. Virol , vol.75 , pp. 9077-9086
    • Buerger, I.1    Reefschlaeger, J.2    Bender, W.3
  • 31
    • 0034855634 scopus 로고    scopus 로고
    • A novel nonnucle-oside inhibitor specifically targets cytomegalovirus DNA mat-uration via the UL89 and UL56 gene products
    • Buerger, I., Reefschlaeger, J., Bender, W. (2001). A novel nonnucle-oside inhibitor specifically targets cytomegalovirus DNA mat-uration via the UL89 and UL56 gene products. J. Virol., 75, 9077-9086.
    • (2001) J. Virol , vol.75 , pp. 9077-9086
    • Buerger, I.1    Reefschlaeger, J.2    Bender, W.3
  • 32
    • 0024599231 scopus 로고
    • Alpha-, beta-and gammaherpesviruses encode a putative phosphotrans-ferase
    • Chee, M. S., Lawrence, G. L., and Barrell, B. G. (1989). Alpha-, beta-and gammaherpesviruses encode a putative phosphotrans-ferase. J. Gen. Virol., 70(5), 1151-1160.
    • (1989) J. Gen. Virol , vol.70 , Issue.5 , pp. 1151-1160
    • Chee, M.S.1    Lawrence, G.L.2    Barrell, B.G.3
  • 34
    • 0038574429 scopus 로고    scopus 로고
    • Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus
    • Chou, S., Lurain, N. S., Thompson, K. D., Miner, R. C., and Drew, W. L. (2003). Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. J. Infect. Dis., 188, 32-39.
    • (2003) J. Infect. Dis , vol.188 , pp. 32-39
    • Chou, S.1    Lurain, N.S.2    Thompson, K.D.3    Miner, R.C.4    Drew, W.L.5
  • 35
    • 2942676471 scopus 로고    scopus 로고
    • Mutations in the human cytomegalovirus UL27 gene that confer resistance to maribavir
    • Chou, S., Marousek, G. I., Senters, A. E., Davis, M. G., and Biron, K. K. (2004). Mutations in the human cytomegalovirus UL27 gene that confer resistance to maribavir. J. Virol., 78, 7124-7130.
    • (2004) J. Virol , vol.78 , pp. 7124-7130
    • Chou, S.1    Marousek, G.I.2    Senters, A.E.3    Davis, M.G.4    Biron, K.K.5
  • 36
    • 0033281797 scopus 로고    scopus 로고
    • Development of novel benzimidazole riboside compounds for treatment of cytomegalovirus disease
    • Chulay, J., Biron, K., Wang L. et al. (1999). Development of novel benzimidazole riboside compounds for treatment of cytomegalovirus disease. Adv. Exp. Med Biol., 458, 129-134.
    • (1999) Adv. Exp. Med Biol , vol.458 , pp. 129-134
    • Chulay, J.1    Biron, K.2    Wang, L.3
  • 37
    • 0042632872 scopus 로고    scopus 로고
    • Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney
    • Ciesla, S. L., Trahan, J., Wan, W. B. et al. (2003). Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney. Antiviral Res., 59, 163-171.
    • (2003) Antiviral Res , vol.59 , pp. 163-171
    • Ciesla, S.L.1    Trahan, J.2    Wan, W.B.3
  • 38
    • 0030457879 scopus 로고    scopus 로고
    • Infection of human T lymphoid cells by human herpesvirus 6 is blocked by two unrelated protein tyrosine kinase inhibitors, biochanin A and herbimycin
    • Cirone, M., Zompetta, C., Tarasi, D., Frati, L., and Faggioni, A. (1996). Infection of human T lymphoid cells by human herpesvirus 6 is blocked by two unrelated protein tyrosine kinase inhibitors, biochanin A and herbimycin. AIDS Res. Hum. Retroviruses, 12, 1629-1634.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 1629-1634
    • Cirone, M.1    Zompetta, C.2    Tarasi, D.3    Frati, L.4    Faggioni, A.5
  • 39
    • 0036109158 scopus 로고    scopus 로고
    • New anti-HSV ther-apeutics target the helicase-primase complex
    • Crumpacker, C. S. and Schaffer, P. A. (2002). New anti-HSV ther-apeutics target the helicase-primase complex. Nat. Med., 8, 327-328.
    • (2002) Nat. Med , vol.8 , pp. 327-328
    • Crumpacker, C.S.1    Schaffer, P.A.2
  • 41
    • 0036107516 scopus 로고    scopus 로고
    • Herpessimplex virus helicase-primase inhibitors are active in animal models of human disease
    • Crute, J. J., Grygon, C. A., Hargrave, K. D. et al. (2002). Herpessimplex virus helicase-primase inhibitors are active in animal models of human disease. Nat. Med., 8, 386-391.
    • (2002) Nat. Med , vol.8 , pp. 386-391
    • Crute, J.J.1    Grygon, C.A.2    Hargrave, K.D.3
  • 42
    • 9144257874 scopus 로고    scopus 로고
    • Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423
    • De Bolle, L., Andrei, G., Snoeck, R. et al. (2004). Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423. Biochem. Pharmacol., 67, 325-336.
    • (2004) Biochem. Pharmacol , vol.67 , pp. 325-336
    • De Bolle, L.1    Andrei, G.2    Snoeck, R.3
  • 43
    • 0036803250 scopus 로고    scopus 로고
    • Cidofovir in the therapy and short-term pro-phylaxis of poxvirus infections
    • De Clercq, E. (2002). Cidofovir in the therapy and short-term pro-phylaxis of poxvirus infections. Trends Pharmacol. Sci., 23, 456-458.
    • (2002) Trends Pharmacol. Sci , vol.23 , pp. 456-458
    • De Clercq, E.1
  • 44
    • 0037404522 scopus 로고    scopus 로고
    • Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyr-imidine nucleoside analogues
    • De Clercq, E. (2003a). Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyr-imidine nucleoside analogues. Med. Res. Rev., 23, 253-274.
    • (2003) Med. Res. Rev , vol.23 , pp. 253-274
    • De Clercq, E.1
  • 45
    • 0037764114 scopus 로고    scopus 로고
    • New inhibitors of human cytomegalovirus (HCMV) on the horizon
    • De Clercq, E. (2003b). New inhibitors of human cytomegalovirus (HCMV) on the horizon. J. Antimicrob. Chemother., 51, 1079-1083.
    • (2003) J. Antimicrob. Chemother , vol.51 , pp. 1079-1083
    • De Clercq, E.1
  • 46
    • 0028045097 scopus 로고
    • Metabolic fate and phar-macokinetics of the acyclovir prodrug valaciclovir in cynomol-gus monkeys
    • De Miranda, P. and Burnette, T. C. (1994). Metabolic fate and phar-macokinetics of the acyclovir prodrug valaciclovir in cynomol-gus monkeys. Drug Metab. Dispos., 22, 55-59.
    • (1994) Drug Metab. Dispos , vol.22 , pp. 55-59
    • De Miranda, P.1    Burnette, T.C.2
  • 47
    • 0026541051 scopus 로고
    • Species differences in the metabolism and disposition of antiviral analogues
    • De Miranda, P. and Good, S. S. (1992). Species differences in the metabolism and disposition of antiviral analogues. Antiviral Chem. Chemo., 3, 1-8.
    • (1992) Antiviral Chem. Chemo , vol.3 , pp. 1-8
    • De Miranda, P.1    Good, S.S.2
  • 48
    • 0023144726 scopus 로고
    • Structure-activity studies of 5-[[4-(4,5-dihydro-2-oxazolyl) phenoxy]alkyl]-3-methylisoxazoles: Inhibitors of picornavirus uncoating
    • Diana, G. D., Oglesby, R. C., Akullian, V. et al. (1987). Structure-activity studies of 5-[[4-(4,5-dihydro-2-oxazolyl) phenoxy]alkyl]-3-methylisoxazoles: Inhibitors of picornavirus uncoating. J. Med. Chem., 30, 383-388.
    • (1987) J. Med. Chem , vol.30 , pp. 383-388
    • Diana, G.D.1    Oglesby, R.C.2    Akullian, V.3
  • 49
    • 27744431876 scopus 로고    scopus 로고
    • Interaction of the putative human cytomegalovirus portal protein pUL104 with the large terminase subunit pUL56 and its inhibition by benzimidazole-D-ribonucleosides
    • Dittmer, A., Drach, J. C., Townsend, L., Fischer, A., and Bogner, E. (2005). Interaction of the putative human cytomegalovirus portal protein pUL104 with the large terminase subunit pUL56 and its inhibition by benzimidazole-D-ribonucleosides. J. Virol., 79, 14660-14667.
    • (2005) J. Virol , vol.79 , pp. 14660-14667
    • Dittmer, A.1    Drach, J.C.2    Townsend, L.3    Fischer, A.4    Bogner, E.5
  • 53
    • 0024992935 scopus 로고
    • Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor com-plexed to HIV-1 protease
    • Erickson, J., Neidhart, D. J., VanDrie, J. et al. (1990). Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor com-plexed to HIV-1 protease. Science, 249, 527-533.
    • (1990) Science , vol.249 , pp. 527-533
    • Erickson, J.1    Neidhart, D.J.2    Van Drie, J.3
  • 54
    • 4644342878 scopus 로고    scopus 로고
    • Inhibition of human cytomegalovirus replication by benzimidazole nucle-osides involves three distinct mechanisms
    • Evers, D. L., Komazin, G., Ptak, R. G. et al. (2004). Inhibition of human cytomegalovirus replication by benzimidazole nucle-osides involves three distinct mechanisms. Antimicrob. Agents Chemother., 48, 3918-3927.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 3918-3927
    • Evers, D.L.1    Komazin, G.2    Ptak, R.G.3
  • 55
    • 0035369086 scopus 로고    scopus 로고
    • Structure of the replicating complex of a pol alpha family DNA polymerase
    • Franklin, M. C., Wang, J., and Steitz, T. A. (2001). Structure of the replicating complex of a pol alpha family DNA polymerase. Cell, 105, 657-667.
    • (2001) Cell , vol.105 , pp. 657-667
    • Franklin, M.C.1    Wang, J.2    Steitz, T.A.3
  • 56
    • 0036143222 scopus 로고    scopus 로고
    • Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity fac-tor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94
    • Gershburg, E. and Pagano, J. S. (2002). Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity fac-tor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94. J. Virol., 76, 998-1003.
    • (2002) J. Virol , vol.76 , pp. 998-1003
    • Gershburg, E.1    Pagano, J.S.2
  • 57
    • 0000058254 scopus 로고
    • Assembling a herpesvirus serine maturational proteinase and a new molec-ular target for antivirals
    • Gibson, W., Welch, A. R., and Hall, W. R. T. (1994). Assembling a herpesvirus serine maturational proteinase and a new molec-ular target for antivirals. Perspect Drug Discov Design, 2, 413-416.
    • (1994) Perspect Drug Discov Design , vol.2 , pp. 413-416
    • Gibson, W.1    Welch, A.R.2    Hall, W.R.T.3
  • 58
    • 0000093809 scopus 로고
    • The disposition in rats and monkeys of 2-bromo-5,6,-dicholoro-1-(beta-ribofuranosyl)benzimididazole (BDCRB) and its 2,5,6-trichloro congener (TCRB)
    • Good, S. S., Owens, B. S., Townsend, L. B., and Drach, J. C.(1994). The disposition in rats and monkeys of 2-bromo-5,6,-dicholoro-1-(beta-ribofuranosyl)benzimididazole (BDCRB) and its 2,5,6-trichloro congener (TCRB). Antivir. Res., 23, 103.
    • (1994) Antivir. Res. , vol.23 , pp. 103
    • Good, S.S.1    Owens, B.S.2    Townsend, L.B.3    Drach, J.C.4
  • 59
    • 0033428970 scopus 로고    scopus 로고
    • Helicase motifs: The engine that powers DNA unwinding
    • Hall, M. C. and Matson, S. W. (1999). Helicase motifs: The engine that powers DNA unwinding. Mol. Microbiol., 34, 867-877.
    • (1999) Mol. Microbiol , vol.34 , pp. 867-877
    • Hall, M.C.1    Matson, S.W.2
  • 60
    • 18644383535 scopus 로고    scopus 로고
    • Novel ben-zthiodiazepinones as antiherpetic agents: SAR improvement of therapeutic index by alterations of the seven-membered ring
    • Hamilton, H. W., Nishiguchi, G., Hagen, S. E. et al. (2002). Novel ben-zthiodiazepinones as antiherpetic agents: SAR improvement of therapeutic index by alterations of the seven-membered ring. Bioorg. Med Chem. Lett., 12, 2981-2983.
    • (2002) Bioorg. Med Chem. Lett , vol.12 , pp. 2981-2983
    • Hamilton, H.W.1    Nishiguchi, G.2    Hagen, S.E.3
  • 61
    • 0034039073 scopus 로고    scopus 로고
    • Avoidance of bone marrow suppression using A-5021 as a nucleoside analog for retrovirus-mediated herpes simplex virus type I thymidine kinase gene therapy
    • Hasegawa, Y., Nishiyama, Y., Imaizumi, K. et al. (2000). Avoidance of bone marrow suppression using A-5021 as a nucleoside analog for retrovirus-mediated herpes simplex virus type I thymidine kinase gene therapy. Cancer Gene Ther., 7, 557-562.
    • (2000) Cancer Gene Ther , vol.7 , pp. 557-562
    • Hasegawa, Y.1    Nishiyama, Y.2    Imaizumi, K.3
  • 62
    • 0031060542 scopus 로고    scopus 로고
    • The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines
    • He, Z., He, Y. S., Kim, Y. et al. (1997). The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines. J. Virol., 71, 405-411.
    • (1997) J. Virol , vol.71 , pp. 405-411
    • He, Z.1    He, Y.S.2    Kim, Y.3
  • 63
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi, H., Kaisho, T., Takeuchi, O. et al. (2002). Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat. Immunol., 3, 196-200.
    • (2002) Nat. Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3
  • 64
    • 0034788245 scopus 로고    scopus 로고
    • Antiviral activity and ocular kinetics of antisense oligonucleotides designed to inhibit CMV replication
    • Henry, S. P., Miner, R. C., Drew, W. L. et al. (2001). Antiviral activity and ocular kinetics of antisense oligonucleotides designed to inhibit CMV replication. Invest.Ophthalmol. Vis.Sci., 42, 2646-2651.
    • (2001) Invest.Ophthalmol. Vis.Sci , vol.42 , pp. 2646-2651
    • Henry, S.P.1    Miner, R.C.2    Drew, W.L.3
  • 65
    • 7244224920 scopus 로고    scopus 로고
    • Novel chemical class of pUL97 pro-tein kinase-specific inhibitors with strong anticytomegaloviral activity
    • Herget, T., Freitag, M., Morbitzer, M., Kupfer, R., Stamminger, T., and Marschall, M. (2004). Novel chemical class of pUL97 pro-tein kinase-specific inhibitors with strong anticytomegaloviral activity. Antimicrob. Agents Chemother., 48, 4154-4162.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 4154-4162
    • Herget, T.1    Freitag, M.2    Morbitzer, M.3    Kupfer, R.4    Stamminger, T.5    Marschall, M.6
  • 66
    • 0030923941 scopus 로고    scopus 로고
    • Herpesvirus proteases: Targets for novel antiviral drugs
    • Holwerda, B. C. (1997). Herpesvirus proteases: Targets for novel antiviral drugs. Antiviral Res., 35, 1-21.
    • (1997) Antiviral Res , vol.35 , pp. 1-21
    • Holwerda, B.C.1
  • 67
    • 0030720252 scopus 로고    scopus 로고
    • Active site cavity of herpesvirus proteases revealed by the crystal structure of her-pes simplex virus protease/inhibitor complex
    • Hoog, S. S., Smith, W. W., Qiu, X. et al. (1997). Active site cavity of herpesvirus proteases revealed by the crystal structure of her-pes simplex virus protease/inhibitor complex. Biochemistry, 56, 14023-14029.
    • (1997) Biochemistry , vol.56 , pp. 14023-14029
    • Hoog, S.S.1    Smith, W.W.2    Qiu, X.3
  • 68
    • 20444377669 scopus 로고    scopus 로고
    • Varicella-zoster virus open read-ing frame 47 (ORF47) protein is critical for virus replication in dendritic cells and for spread to other cells
    • Hu, H. and Cohen, J. I. (2005). Varicella-zoster virus open read-ing frame 47 (ORF47) protein is critical for virus replication in dendritic cells and for spread to other cells. Virology, 337, 304-311.
    • (2005) Virology , vol.337 , pp. 304-311
    • Hu, H.1    Cohen, J.I.2
  • 69
    • 0002960951 scopus 로고    scopus 로고
    • Orally active ether lipid prodrugs of cidofovir for the treatment of smallpox
    • Huggins, J. W., Baker, R. O., Beadle, J. R., and Hostetler, K. Y. (2002). Orally active ether lipid prodrugs of cidofovir for the treatment of smallpox. Antivir. Res., 53, A66, 104.
    • (2002) Antivir. Res , vol.53 , pp. 66-104
    • Huggins, J.W.1    Baker, R.O.2    Beadle, J.R.3    Hostetler, K.Y.4
  • 70
    • 0031807360 scopus 로고    scopus 로고
    • Antiherpesvirus activities of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl)cycloprop-1?-yl]methyl]guanine (A-5021) in cell culture
    • Iwayama. S., Ono. N., Ohmura, Y. et al. (1998). Antiherpesvirus activities of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl)cycloprop-1?-yl]methyl]guanine (A-5021) in cell culture. Antimicrob. Agents Chemother., 42, 1666-1670.
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 1666-1670
    • Iwayama, S.1    Ono, N.2    Ohmura, Y.3
  • 71
    • 0032947297 scopus 로고    scopus 로고
    • Eval-uation of anti-herpesvirus activity of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl)cycloprop-1?-yl]methyl]-guanine (A-5021) in mice
    • Iwayama, S., Ohmura, Y., Suzuki, K. et al. (1999). Eval-uation of anti-herpesvirus activity of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl)cycloprop-1?-yl]methyl]-guanine (A-5021) in mice. Antiviral Res., 42, 139-148.
    • (1999) Antiviral Res , vol.42 , pp. 139-148
    • Iwayama, S.1    Ohmura, Y.2    Suzuki, K.3
  • 72
    • 0032818692 scopus 로고    scopus 로고
    • Non-nucleoside pyrrolopyrimidines with a unique mechanism of action against human cytomegalovirus
    • Jacobson, J. G., Renau, T. E., Nassiri, M. R. et al. (1999). Non-nucleoside pyrrolopyrimidines with a unique mechanism of action against human cytomegalovirus. Antimicrob. Agents Chemother., 43, 1888-1894.
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 1888-1894
    • Jacobson, J.G.1    Renau, T.E.2    Nassiri, M.R.3
  • 73
    • 31144450021 scopus 로고    scopus 로고
    • Herpes simplex virus 1-encoded protein kinase UL13 phosphorylates viral Us3 pro-tein kinase and regulates nuclear localization of viral envelop-ment factors UL34 and UL31
    • Kato, A., Yamamoto, M., Ohno, T. et al. (2006). Herpes simplex virus 1-encoded protein kinase UL13 phosphorylates viral Us3 pro-tein kinase and regulates nuclear localization of viral envelop-ment factors UL34 and UL31. J. Virol., 80, 1476-1486.
    • (2006) J. Virol , vol.80 , pp. 1476-1486
    • Kato, A.1    Yamamoto, M.2    Ohno, T.3
  • 74
    • 0041837470 scopus 로고    scopus 로고
    • Protein kinases conserved in her-pesviruses potentially share a function mimicking the cellular protein kinase cdc2
    • Kawaguchi, Y. and Kato, K. (2003). Protein kinases conserved in her-pesviruses potentially share a function mimicking the cellular protein kinase cdc2. Rev. Med. Virol., 13, 331-340.
    • (2003) Rev. Med. Virol , vol.13 , pp. 331-340
    • Kawaguchi, Y.1    Kato, K.2
  • 75
    • 0037282348 scopus 로고    scopus 로고
    • In vitro activity of potential anti-proxvirus agents
    • Kern, E. R. (2003). In vitro activity of potential anti-proxvirus agents. Antiviral Res., 57, 35-40.
    • (2003) Antiviral Res , vol.57 , pp. 35-40
    • Kern, E.R.1
  • 77
    • 0037315768 scopus 로고    scopus 로고
    • Novel agents and strategies to treat herpes simplex virus infections
    • Kleymann, G. (2003a). Novel agents and strategies to treat herpes simplex virus infections. Expert. Opin. Investig. Drugs, 12, 165-183.
    • (2003) Expert. Opin. Investig. Drugs , vol.12 , pp. 165-183
    • Kleymann, G.1
  • 78
    • 0013118133 scopus 로고    scopus 로고
    • Helicase-primase inhibitors
    • Kleymann, G. (2003b). Helicase-primase inhibitors. Drugs of the Future, 28, 257-265.
    • (2003) Drugs of the Future , vol.28 , pp. 257-265
    • Kleymann, G.1
  • 79
    • 0036111626 scopus 로고    scopus 로고
    • New helicase-primase inhibitors as drug candidates for the treatment of her-pes simplex disease
    • Kleymann, G., Fischer, R., Betz, U. A. et al. (2002). New helicase-primase inhibitors as drug candidates for the treatment of her-pes simplex disease. Nat. Med., 8, 392-398.
    • (2002) Nat. Med , vol.8 , pp. 392-398
    • Kleymann, G.1    Fischer, R.2    Betz, U.A.3
  • 80
    • 0036779234 scopus 로고    scopus 로고
    • Inhibition of clinical isolates of human cytomegalovirus and varicella zoster virus by PNU-183792, a 4-oxo-dihydroquinoline
    • Knechtel, M. L., Huang, A., Vaillancourt, V. A., and Brideau, R. J. (2002). Inhibition of clinical isolates of human cytomegalovirus and varicella zoster virus by PNU-183792, a 4-oxo-dihydroquinoline. J. Med. Virol., 68, 234-236.
    • (2002) J. Med. Virol , vol.68 , pp. 234-236
    • Knechtel, M.L.1    Huang, A.2    Vaillancourt, V.A.3    Brideau, R.J.4
  • 81
    • 1342321886 scopus 로고    scopus 로고
    • KSHV LA NA-1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA replication and episome persistence
    • Komatsu, T., Ballestras, M. E., Barbera, A. J., Kelly-Clarke, B., and Kaye, K. M. (2004). KSHV LA NA-1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA replication and episome persistence. Virol-ogy, 319, 225-236.
    • (2004) Virol-ogy , vol.319 , pp. 225-236
    • Komatsu, T.1    Ballestras, M.E.2    Barbera, A.J.3    Kelly-Clarke, B.4    Kaye, K.M.5
  • 82
    • 0035991712 scopus 로고    scopus 로고
    • Preclinicat and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication
    • Koszalka, G. W., Johnson, N. W., Good, S. S. (2002). Preclinicat and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication. Antimicrob. Agents Chemother, 46, 2373-2380.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 2373-2380
    • Koszalka, G.W.1    Johnson, N.W.2    Good, S.S.3
  • 83
    • 0142124151 scopus 로고    scopus 로고
    • Resistance of human cytomegalovirus to the ben-zimidazole L-ribonucleoside maribavir maps to UL27
    • Komazin, G., Ptak, R. G., Emmer, B. T., Townsend, L. B, and Drach, J. C. (2003). Resistance of human cytomegalovirus to the ben-zimidazole L-ribonucleoside maribavir maps to UL27. J Virol., 77, 11499-11506.
    • (2003) J Virol , vol.77 , pp. 11499-11506
    • Komazin, G.1    Ptak, R.G.2    Emmer, B.T.3    Townsend, L.B.4    Drach, J.C.5
  • 84
    • 0346688644 scopus 로고    scopus 로고
    • Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides
    • Komazin, G., Townsend, L. B., and Drach, J. C. (2004). Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides. J. Virol., 78, 710-715.
    • (2004) J. Virol , vol.78 , pp. 710-715
    • Komazin, G.1    Townsend, L.B.2    Drach, J.C.3
  • 85
    • 0038082392 scopus 로고    scopus 로고
    • The human cytomegalovirus UL44 protein is a substrate for the UL97 pro-tein kinase
    • Krosky, P. M., Baek, M. C., Jahng, W. J. et al. (2003b). The human cytomegalovirus UL44 protein is a substrate for the UL97 pro-tein kinase. J. Virol., 77, 7720-7727.
    • (2003) J. Virol , vol.77 , pp. 7720-7727
    • Krosky, P.M.1    Baek, M.C.2    Jahng, W.J.3
  • 86
    • 0037225808 scopus 로고    scopus 로고
    • The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress
    • Krosky, P. M., Baek, M. C., and Coen, D. M. (2003a). The human cytomegalovirus UL97 protein kinase, an antiviral drug target, is required at the stage of nuclear egress. J. Virol., 77, 905-914.
    • (2003) J. Virol , vol.77 , pp. 905-914
    • Krosky, P.M.1    Baek, M.C.2    Coen, D.M.3
  • 87
    • 0031946070 scopus 로고    scopus 로고
    • Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56
    • Krosky, P. M., Underwood, M. R., Turk, S.R. et al. (1998). Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56. J. Virol., 72, 4721-4728.
    • (1998) J. Virol , vol.72 , pp. 4721-4728
    • Krosky, P.M.1    Underwood, M.R.2    Turk, S.R.3
  • 89
    • 0031108088 scopus 로고    scopus 로고
    • New treatment options for CMV retinitis in AIDS
    • Lalezari, J. P. (1997). New treatment options for CMV retinitis in AIDS. Adv. Nurse Pract., 5, 45-9.
    • (1997) Adv. Nurse Pract , vol.5 , pp. 45-49
    • Lalezari, J.P.1
  • 90
    • 0028936048 scopus 로고
    • (S)-1[3-hydroxy-2-(phosphonylmethoxy)propyl] cytosine (cidofovir): Results of a phase I/II study of a novel antiviral nucleotide analogue
    • Lalezari, J. P., Drew, W. L., Glutzer, E. et al. (1995). (S)-1[3-hydroxy-2-(phosphonylmethoxy)propyl] cytosine (cidofovir): Results of a phase I/II study of a novel antiviral nucleotide analogue. J. Infect. Dis., 171, 788-796.
    • (1995) J. Infect. Dis , vol.171 , pp. 788-796
    • Lalezari, J.P.1    Drew, W.L.2    Glutzer, E.3
  • 91
    • 0036720595 scopus 로고    scopus 로고
    • Phase I dose escalation trial evaluating the pharmacokinetics, anti-human cytomegalovirus (HCMV) activity, and safety of 1263W94 in human immunodeficiency virus-infected men with asymp-tomatic HCMV shedding
    • Lalezari, J. P., Aberg, J. A., Wang, L. H. et al. (2002). Phase I dose escalation trial evaluating the pharmacokinetics, anti-human cytomegalovirus (HCMV) activity, and safety of 1263W94 in human immunodeficiency virus-infected men with asymp-tomatic HCMV shedding. Antimicrob. Agents Chemother., 46, 2969-2976.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 2969-2976
    • Lalezari, J.P.1    Aberg, J.A.2    Wang, L.H.3
  • 92
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate sol-ubility and permeability in drug discovery and development settings
    • Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. (2001). Experimental and computational approaches to estimate sol-ubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev., 46, 3-26
    • (2001) Adv. Drug Deliv. Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 93
    • 0026664424 scopus 로고
    • Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganci-clovir
    • Littler, E., Stuart, A. D., and Chee, M. S. (1992). Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganci-clovir. Nature, 358, 160-162.
    • (1992) Nature , vol.358 , pp. 160-162
    • Littler, E.1    Stuart, A.D.2    Chee, M.S.3
  • 94
    • 8644267364 scopus 로고    scopus 로고
    • Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase
    • Liuzzi, M., Kibler, P., Bousquet, C. et al. (2004). Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase. Antiviral Res., 64, 161-170.
    • (2004) Antiviral Res , vol.64 , pp. 161-170
    • Liuzzi, M.1    Kibler, P.2    Bousquet, C.3
  • 95
    • 32844463538 scopus 로고    scopus 로고
    • Selectiveanti-cytomegalovirus compounds discoverd by screening for inhibitors of subunit interactions of the viral polymerase, Chem
    • Loregian, A., and Coen, D. M.(2006). Selectiveanti-cytomegalovirus compounds discoverd by screening for inhibitors of subunit interactions of the viral polymerase, Chem. Biol., 13, 191-200.
    • (2006) Biol , vol.13 , pp. 191-200
    • Loregian, A.1    Coen, D.M.2
  • 96
    • 33646778183 scopus 로고    scopus 로고
    • N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole
    • Lorenzi, P. L., Landowski, C. P., Brancale, A. et al. (2006). N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole. Drug Metab. Dispos., 34, 1070-1077.
    • (2006) Drug Metab. Dispos , vol.34 , pp. 1070-1077
    • Lorenzi, P.L.1    Landowski, C.P.2    Brancale, A.3
  • 97
    • 22944459555 scopus 로고    scopus 로고
    • Amino acid ester prodrugs of 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole enhance metabolic stability in vitro and in vivo
    • Lorenzi, P. L., Landowski, C. P., Song, X. et al. (2005). Amino acid ester prodrugs of 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole enhance metabolic stability in vitro and in vivo. J. Pharmacol. Exp. Ther., 314, 883-890.
    • (2005) J. Pharmacol. Exp. Ther , vol.314 , pp. 883-890
    • Lorenzi, P.L.1    Landowski, C.P.2    Song, X.3
  • 98
    • 0041631012 scopus 로고    scopus 로고
    • Cell culture replication of her-pes simplex virus and, or human cytomegalovirus is inhibited by 3,7-dialkoxylated, 1-hydroxyacridone derivatives
    • Lowden, C. T. and Bastow, K. F. (2003). Cell culture replication of her-pes simplex virus and, or human cytomegalovirus is inhibited by 3,7-dialkoxylated, 1-hydroxyacridone derivatives. Antiviral Res., 59, 143-154.
    • (2003) Antiviral Res , vol.59 , pp. 143-154
    • Lowden, C.T.1    Bastow, K.F.2
  • 99
    • 0029098966 scopus 로고
    • Mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine against herpesviruses
    • Lowe, D. M., Alderton, W. K., Ellis M. R. et al. (1995). Mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine against herpesviruses. Antimicrob. Agents Chemother., 39, 1802-1808.
    • (1995) Antimicrob. Agents Chemother , vol.39 , pp. 1802-1808
    • Lowe, D.M.1    Alderton, W.K.2    Ellis, M.R.3
  • 101
    • 0034812453 scopus 로고    scopus 로고
    • Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing
    • Lurain, N. S., Weinberg, A., Crumpacker, C. S., and Chou S. (2001). Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing. Antimicrob. Agents Chemother., 45, 2775-2780.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 2775-2780
    • Lurain, N.S.1    Weinberg, A.2    Crumpacker, C.S.3    Cho, S.4
  • 102
    • 33645774160 scopus 로고    scopus 로고
    • Maribavir pharmacokinetics and the effects of multiple-dose maribavir on cytochrome P450 (CYP) 1A2, CYP 2C9, CYP 2C19, CYP 2D6, CYP 3A, N-acetyltransferase-2, and xanthine oxidase activities in healthy adults
    • Ma, J. D., Nafziger, A. N., Villano, S. A., and J. S., Jr. (2006). Maribavir pharmacokinetics and the effects of multiple-dose maribavir on cytochrome P450 (CYP) 1A2, CYP 2C9, CYP 2C19, CYP 2D6, CYP 3A, N-acetyltransferase-2, and xanthine oxidase activities in healthy adults. Antimicrob. Agents Chemother., 50, 1130-1135
    • (2006) Antimicrob. Agents Chemother , vol.50 , pp. 1130-1135
    • Ma, J.D.1    Nafziger, A.N.2    Villano, S.A.J.S.3
  • 103
    • 0034982838 scopus 로고    scopus 로고
    • Inhibitors of human cytomegalovirus replication drastically reduce the activ-ity of the viral protein kinase pUL97
    • Marschall, M., Stein-Gerlach, M., Freitage, M., Kupfer, R., van Den, BM., and Stamminger, T. (2001). Inhibitors of human cytomegalovirus replication drastically reduce the activ-ity of the viral protein kinase pUL97. J.Gen. Virol., 82, 1439-1450.
    • (2001) J.Gen. Virol , vol.82 , pp. 1439-1450
    • Marschall, M.1    Stein-Gerlach, M.2    Freitage, M.3    Kupfer, R.4    Van Den, B.5    Stamminger, T.6
  • 104
    • 0037708793 scopus 로고    scopus 로고
    • The protein kinase pUL97 ofhumancytomegalovirusinteractswithandphospho-rylates the DNA polymerase processivity factor pUL44
    • Marschall, M., Freitag, M., Suchy, P. et al. (2003). The protein kinase pUL97 ofhumancytomegalovirusinteractswithandphospho-rylates the DNA polymerase processivity factor pUL44. Virol-ogy, 311, 60-71.
    • (2003) Virol-ogy , vol.311 , pp. 60-71
    • Marschall, M.1    Freitag, M.2    Suchy, P.3
  • 105
    • 25844443739 scopus 로고    scopus 로고
    • Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina
    • Marschall, M., Marzi, A., aus dem, S. P., et al., (2005). Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina. J. Biol. Chem., 280, 33357-33367.
    • (2005) J. Biol. Chem , vol.280 , pp. 33357-33367
    • Marschall, M.1    Marzi, A.2    Aus Dem, S.P.3
  • 106
    • 0027492163 scopus 로고
    • The structure and function of the HSV DNA replication proteins: Defining novel antiviral targets
    • Matthews, J. T., Terry, B. J., and Field, A. K. (1993). The structure and function of the HSV DNA replication proteins: Defining novel antiviral targets. Antiviral Res., 20, 89-114.
    • (1993) Antiviral Res , vol.20 , pp. 89-114
    • Matthews, J.T.1    Terry, B.J.2    Field, A.K.3
  • 107
    • 0042737895 scopus 로고    scopus 로고
    • Halophenyl fura-nopyrimidines as potent and selective anti-VZV agents
    • McGuigan, C., Jukes, A., Blewett, S. et al. (2003). Halophenyl fura-nopyrimidines as potent and selective anti-VZV agents. Antivir. Chem. Chemother., 14, 165-170.
    • (2003) Antivir. Chem. Chemother , vol.14 , pp. 165-170
    • Mc Guigan, C.1    Jukes, A.2    Blewett, S.3
  • 108
    • 0034810929 scopus 로고    scopus 로고
    • Susceptibili-ties of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir
    • McSharry, J. J., McDonough, A., Olson, B. et al. (2001a). Susceptibili-ties of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir. Antimicrob. Agents Chemother., 45, 2925-2927.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 2925-2927
    • Mc Sharry, J.J.1    Mc Donough, A.2    Olson, B.3
  • 109
    • 0034755874 scopus 로고    scopus 로고
    • Inhibition of ganciclovir-susceptible and-resistant human cytomegalovirus clinical isolates by the benzimidazole L-riboside 1263W94
    • McSharry, J. J., McDonough, A., Olson, B., Talarico, C., Davis, M., and Biron, K. K. (2001b). Inhibition of ganciclovir-susceptible and-resistant human cytomegalovirus clinical isolates by the benzimidazole L-riboside 1263W94. Clin. Diagn. Lab. Immunol., 8, 1279-1281.
    • (2001) Clin. Diagn. Lab. Immunol , vol.8 , pp. 1279-1281
    • Mc Sharry, J.J.1    Mc Donough, A.2    Olson, B.3    Talarico, C.4    Davis, M.5    Biron, K.K.6
  • 110
    • 23844490714 scopus 로고    scopus 로고
    • Impact of 2-bromo-5,6-dichloro-1-beta-D-ribofuranosyl benzimidazole riboside and inhibitors of DNA, RNA, and protein synthesis on human cytomegalovirus genome maturation
    • McVoy, M. A. and Nixon, D. E. (2005). Impact of 2-bromo-5,6-dichloro-1-beta-D-ribofuranosyl benzimidazole riboside and inhibitors of DNA, RNA, and protein synthesis on human cytomegalovirus genome maturation. J. Virol., 79, 11115-11127.
    • (2005) J. Virol , vol.79 , pp. 11115-11127
    • Mc Voy, M.A.1    Nixon, D.E.2
  • 111
    • 0036148284 scopus 로고    scopus 로고
    • Herpesvirus assembly and egress
    • Mettenleiter, T. C. (2002). Herpesvirus assembly and egress. J Virol., 76, 1537-1547.
    • (2002) J Virol , vol.76 , pp. 1537-1547
    • Mettenleiter, T.C.1
  • 112
    • 0029841220 scopus 로고    scopus 로고
    • The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase
    • Michel, D., Pavic, I., Zimmermann, A. et al. (1996). The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase. J. Virol., 70, 6340-6346.
    • (1996) J. Virol , vol.70 , pp. 6340-6346
    • Michel, D.1    Pavic, I.2    Zimmermann, A.3
  • 113
    • 0036181703 scopus 로고    scopus 로고
    • Immunomodulation as a treatment strategy for genital herpes: Review of the evidence
    • Miller, R. L., Tomai, M. A., Harrison, C. J., and Bernstein, D. I. (2002). Immunomodulation as a treatment strategy for genital herpes: Review of the evidence. Int. Immunopharmacol., 2, 443-451.
    • (2002) Int. Immunopharmacol , vol.2 , pp. 443-451
    • Miller, R.L.1    Tomai, M.A.2    Harrison, C.J.3    Bernstein, D.I.4
  • 114
    • 0032578408 scopus 로고    scopus 로고
    • The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse
    • Moffat, J. F., Zerboni, L., Sommer, M. H. et al. (1998). The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse. Proc. Natl Acad. Sci. USA, 95, 11969-11974.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 11969-11974
    • Moffat, J.F.1    Zerboni, L.2    Sommer, M.H.3
  • 115
    • 0010622298 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinet-ics of single oral doses of BAY 38-4766-a novel nonnucle-osidic inhibitor of human cytomegalovirus (HCMV) replica-tion-in healthy male subjects
    • San Francisco, CA, Abstract
    • Nagelschmitz, J., Moeller, J. G., Stass, H. H., Wadel, C., and Kuhlmann, J. (1999). Safety, tolerability, and pharmacokinet-ics of single oral doses of BAY 38-4766-a novel nonnucle-osidic inhibitor of human cytomegalovirus (HCMV) replica-tion-in healthy male subjects. In Program and Abstracts of the Thirty-ninth Interscience Conference on Antimicrob Agents and Chemother, San Francisco, CA, Abstract 945, 322.
    • (1999) In Program and Abstracts of the Thirty-ninth Interscience Conference on Antimicrob Agents and Chemother , vol.945 , pp. 322
    • Nagelschmitz, J.1    Moeller, J.G.2    Stass, H.H.3    Wadel, C.4    Kuhlmann, J.5
  • 117
    • 0036776326 scopus 로고    scopus 로고
    • Inhibition of herpes simplex virus replication by WAY-150138: Assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation
    • Newcomb, W. W. and Brown, J. C. (2002). Inhibition of herpes simplex virus replication by WAY-150138: Assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation. J Virol., 76, 10084-10088.
    • (2002) J Virol , vol.76 , pp. 10084-10088
    • Newcomb, W.W.1    Brown, J.C.2
  • 118
    • 0034766951 scopus 로고    scopus 로고
    • The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid
    • Newcomb, W. W., Juhas, R. M., Thomsen, D. R. et al. (2001). The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid. J. Virol., 75, 10923-10932.
    • (2001) J. Virol , vol.75 , pp. 10923-10932
    • Newcomb, W.W.1    Juhas, R.M.2    Thomsen, D.R.3
  • 119
    • 0034766951 scopus 로고    scopus 로고
    • The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid
    • Newcomb, W. W., Juhas, R. M., Thomsen, D. R. et al. (2001). The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid. J. Virol., 75, 10923-10932.
    • (2001) J. Virol , vol.75 , pp. 10923-10932
    • Newcomb, W.W.1    Juhas, R.M.2    Thomsen, D.R.3
  • 120
    • 0141570625 scopus 로고    scopus 로고
    • Assembly of the herpes simplex virus capsid: Identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids
    • Newcomb, W. W., Thomsen, D. R., Homa, F. L., and Brown, J. C. (2003). Assembly of the herpes simplex virus capsid: Identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids. J. Virol., 77, 9862-9871.
    • (2003) J. Virol , vol.77 , pp. 9862-9871
    • Newcomb, W.W.1    Thomsen, D.R.2    Homa, F.L.3    Brown, J.C.4
  • 121
    • 0035251014 scopus 로고    scopus 로고
    • The anti-herpesvirus activity of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl)-cycloprop-1?-yl]methyl]guanine is markedly potentiated by the immuno-suppressive agent mycophenolate mofetil
    • Neyts, J. and De Clercq, E. (2001). The anti-herpesvirus activity of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl)-cycloprop-1?-yl]methyl]guanine is markedly potentiated by the immuno-suppressive agent mycophenolate mofetil. Antiviral Res., 49, 121-127.
    • (2001) Antiviral Res , vol.49 , pp. 121-127
    • Neyts, J.1    De Clercq, E.2
  • 122
    • 0035251196 scopus 로고    scopus 로고
    • Anti-herpesvirus activity of (1? S,2? R)-9-[[1?, 2?-bis(hydroxymethyl)-cycloprop-1?-yl]methyl] x guanine (A-5021) in vitro and in vivo
    • Neyts, J., Naesens, L., Ying, C., De Bolle, L., and De Clercq, E. (2001). Anti-herpesvirus activity of (1? S,2? R)-9-[[1?, 2?-bis(hydroxymethyl)-cycloprop-1?-yl]methyl] x guanine (A-5021) in vitro and in vivo. Antiviral Res., 49, 115-120.
    • (2001) Antiviral Res , vol.49 , pp. 115-120
    • Neyts, J.1    Naesens, L.2    Ying, C.3    De Bolle, L.4    De Clercq, E.5
  • 123
    • 2542468825 scopus 로고    scopus 로고
    • Efficacy of cidofovir in a murine model of disseminated progressive vaccinia
    • Neyts, J., Leyssen, P., Verbeken, E., and De Clercq, E. (2004). Efficacy of cidofovir in a murine model of disseminated progressive vaccinia. Antimicrob. Agents Chemother., 48, 2267-2273.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 2267-2273
    • Neyts, J.1    Leyssen, P.2    Verbeken, E.3    De Clercq, E.4
  • 124
    • 0035018488 scopus 로고    scopus 로고
    • Selection and character-ization of varicella-zoster virus variants resistant to (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine
    • Ng, T. I., Shi, Y., Huffaker, H. J. et al. (2001). Selection and character-ization of varicella-zoster virus variants resistant to (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine. Antimicrob. Agents Chemother., 45, 1629-1636.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 1629-1636
    • Ng, T.I.1    Shi, Y.2    Huffaker, H.J.3
  • 125
    • 0036167879 scopus 로고    scopus 로고
    • Broad-spectrum antiherpes activities of 4-hydroxyquinoline carbox-amides, a novel class of herpesvirus polymerase inhibitors
    • Oien, N. L., Brideau, R. J., Hopkins, T. A. et al. (2002). Broad-spectrum antiherpes activities of 4-hydroxyquinoline carbox-amides, a novel class of herpesvirus polymerase inhibitors. Antimicrob. Agents Chemother., 46, 724-730.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 724-730
    • Oien, N.L.1    Brideau, R.J.2    Hopkins, T.A.3
  • 126
    • 0038520989 scopus 로고    scopus 로고
    • Theevolvingtherapeuticapproachesfor Epstein-Barr virus infection in immunocompetent and immunocom-promised individuals
    • Okano, M.(2003). Theevolvingtherapeuticapproachesfor Epstein-Barr virus infection in immunocompetent and immunocom-promised individuals. Curr. Drug Targets. Immune. Endocr. Metabol. Disord., 3, 137-142.
    • (2003) Curr. Drug Targets. Immune. Endocr. Metabol. Disord , vol.3 , pp. 137-142
    • Okano, M.1
  • 127
    • 0031904278 scopus 로고    scopus 로고
    • Mode of action of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl) cycloprop-1?-yl]methyl]guanine (A-5021) against herpes simplex virus type 1 and type 2 and varicella-zoster virus
    • Ono, N., Iwayama, S., Suzuki, K. et al. (1998). Mode of action of (1? S,2? R)-9-[[1?,2?-bis(hydroxymethyl) cycloprop-1?-yl]methyl]guanine (A-5021) against herpes simplex virus type 1 and type 2 and varicella-zoster virus. Antimicrob. Agents Chemother., 42, 2095-2102.
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 2095-2102
    • Ono, N.1    Iwayama, S.2    Suzuki, K.3
  • 128
    • 3342879034 scopus 로고    scopus 로고
    • Design and development of oral drugs for the prophylaxis and treatment of smallpox infection
    • Painter, G. R. and Hostetler, K.Y. (2004). Design and development of oral drugs for the prophylaxis and treatment of smallpox infection. Trends Biotechnol., 22, 423-427.
    • (2004) Trends Biotechnol , vol.22 , pp. 423-427
    • Painter, G.R.1    Hostetler, K.Y.2
  • 129
    • 29744449915 scopus 로고    scopus 로고
    • Human cytomegalovirus UL97 Kinase is required for the normal intranuclear distribution of pp65 and virion morphogenesis
    • Prichard, M. N., Britt, W. J., Daily, S. L., Hartline, C. B., and Kern, E. R. (2005). Human cytomegalovirus UL97 Kinase is required for the normal intranuclear distribution of pp65 and virion morphogenesis. J. Virol., 79, 15494-15502.
    • (2005) J. Virol , vol.79 , pp. 15494-15502
    • Prichard, M.N.1    Britt, W.J.2    Daily, S.L.3    Hartline, C.B.4    Kern, E.R.5
  • 130
    • 0033033631 scopus 로고    scopus 로고
    • A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency
    • Prichard, M. N., Gao, N., Jairath, S. et al. (1999). A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency. J. Virol., 73, 5663-5670.
    • (1999) J. Virol , vol.73 , pp. 5663-5670
    • Prichard, M.N.1    Gao, N.2    Jairath, S.3
  • 131
    • 0042389525 scopus 로고    scopus 로고
    • Point mutations in exon I of the herpes simplex virus putative terminase subunit, UL15, indicate that the most conserved residues are essential for cleavage and packaging
    • Przech, A. J., Yu, D., and Weller, S. K. (2003). Point mutations in exon I of the herpes simplex virus putative terminase subunit, UL15, indicate that the most conserved residues are essential for cleavage and packaging. J. Virol., 77, 9613-9621.
    • (2003) J. Virol , vol.77 , pp. 9613-9621
    • Przech, A.J.1    Yu, D.2    Weller, S.K.3
  • 132
    • 0002524125 scopus 로고    scopus 로고
    • Human herpes proteases In Dunn
    • B. M., ed. San Diego: Academic Press
    • Qiu, X. Y. and Abdelmeguid, S. S. (1999). Human herpes proteases In Dunn, B. M., ed. Proteases of Infectious Agents. San Diego: Academic Press, 93-115.
    • (1999) Proteases of Infectious Agents , pp. 93-115
    • Qiu, X.Y.1    Abdelmeguid, S.S.2
  • 133
    • 25844517214 scopus 로고    scopus 로고
    • Herpesvirus infections in solid organ transplant patients at high risk of primary cytomegalovirus disease
    • Razonable, R. R., Brown, R. A., Humar, A., Covington, E., Alecock, E., and Paya, C. V. (2005). Herpesvirus infections in solid organ transplant patients at high risk of primary cytomegalovirus disease. J. Infect. Dis., 192, 1331-1339.
    • (2005) J. Infect. Dis , vol.192 , pp. 1331-1339
    • Razonable, R.R.1    Brown, R.A.2    Humar, A.3    Covington, E.4    Alecock, E.5    Paya, C.V.6
  • 134
    • 14044265101 scopus 로고    scopus 로고
    • Cutting edge: Priming of CTL by transcutaneous pep-tide immunization with imiquimod
    • Rechtsteiner, G., Warger, T., Osterloh, P., Schild, H., and Radsak, M. P. (2005). Cutting edge: Priming of CTL by transcutaneous pep-tide immunization with imiquimod. J. Immunol. 174, 2476-2480.
    • (2005) J. Immunol , vol.174 , pp. 2476-2480
    • Rechtsteiner, G.1    Warger, T.2    Osterloh, P.3    Schild, H.4    Radsak, M.P.5
  • 135
    • 0035656411 scopus 로고    scopus 로고
    • Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): In vitro and in vivo antiviral activity and mechanism of action
    • Reefschlaeger, J., Bender, W., Hallenberger, S. et al. (2001). Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): In vitro and in vivo antiviral activity and mechanism of action. J. Antimicrob. Chemother., 48, 757-767.
    • (2001) J. Antimicrob. Chemother , vol.48 , pp. 757-767
    • Reefschlaeger, J.1    Bender, W.2    Hallenberger, S.3
  • 138
    • 0025743001 scopus 로고
    • Antiviral activity of oxetanocins against varicella-zoster virus
    • Sakuma, T., Saijo, M., Suzutani, T. et al. (1991). Antiviral activity of oxetanocins against varicella-zoster virus. Antimicrob. Agents Chemother., 35, 1512-1514.
    • (1991) Antimicrob. Agents Chemother , vol.35 , pp. 1512-1514
    • Sakuma, T.1    Saijo, M.2    Suzutani, T.3
  • 139
    • 0036924593 scopus 로고    scopus 로고
    • Cyclin-dependent kinases as cellular tar-gets for antiviral drugs
    • Schang, L. M. (2002). Cyclin-dependent kinases as cellular tar-gets for antiviral drugs. J. Antimicrob. Chemother., 50, 779-792.
    • (2002) J. Antimicrob. Chemother , vol.50 , pp. 779-792
    • Schang, L.M.1
  • 140
    • 0036310685 scopus 로고    scopus 로고
    • Pharmaco-logical cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellu-lar, not viral, proteins
    • Schang, L. M., Bantly, A., Knockaert, M. et al. (2002). Pharmaco-logical cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellu-lar, not viral, proteins. J. Virol., 76, 7874-7882.
    • (2002) J. Virol , vol.76 , pp. 7874-7882
    • Schang, L.M.1    Bantly, A.2    Knockaert, M.3
  • 141
    • 0036529667 scopus 로고    scopus 로고
    • The terminase subunits pUL56 and pUL89 of human cytomegalovirus are DNA-metabolizing proteins with toroidal structure
    • Scheffczik, H., Savva, C. G., Holzenburg, A., Kolesnikova, L., and Bogner, E. (2002). The terminase subunits pUL56 and pUL89 of human cytomegalovirus are DNA-metabolizing proteins with toroidal structure. Nucl. Acids Res., 30, 1695-1703.
    • (2002) Nucl. Acids Res , vol.30 , pp. 1695-1703
    • Scheffczik, H.1    Savva, C.G.2    Holzenburg, A.3    Kolesnikova, L.4    Bogner, E.5
  • 143
    • 15444359037 scopus 로고    scopus 로고
    • Synthesis and antiviral activity of novel acyclic nucleosides: Discovery of a cyclopropyl nucleoside with potent inhibitory activity against herpesviruses
    • Sekiyama, T., Hatsuya, S., Tanaka, Y. et al. (1998). Synthesis and antiviral activity of novel acyclic nucleosides: Discovery of a cyclopropyl nucleoside with potent inhibitory activity against herpesviruses. J. Med. Chem., 41, 1284-1298.
    • (1998) J. Med. Chem , vol.41 , pp. 1284-1298
    • Sekiyama, T.1    Hatsuya, S.2    Tanaka, Y.3
  • 144
    • 0035098316 scopus 로고    scopus 로고
    • Frequencyofacyclovir-resistantherpessimplexvirusin clinical specimens and laboratory isolates
    • Shin, Y. K., Cai, G. Y., Weinberg, A., Leary, J. J., and Levin, M. J. (2001). Frequencyofacyclovir-resistantherpessimplexvirusin clinical specimens and laboratory isolates. J. Clin. Microbiol., 39, 913-917.
    • (2001) J. Clin. Microbiol , vol.39 , pp. 913-917
    • Shin, Y.K.1    Cai, G.Y.2    Weinberg, A.3    Leary, J.J.4    Levin, M.J.5
  • 145
    • 0032987225 scopus 로고    scopus 로고
    • Viral and host-cell protein kinases: Enticing antiviral targets and relevance of nucleoside, and viral thymi-dine, kinases
    • Shugar, D. (1999). Viral and host-cell protein kinases: Enticing antiviral targets and relevance of nucleoside, and viral thymi-dine, kinases. Pharmacol. Ther., 82, 315-335.
    • (1999) Pharmacol. Ther , vol.82 , pp. 315-335
    • Shugar, D.1
  • 146
    • 1342281674 scopus 로고    scopus 로고
    • Inactivity of the bicyclic pyrimidine nucle-oside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymi-dine kinase
    • Sienaert, R., Andrei, G., Snoeck, R., De Clercq, E., McGuigan, C., and Balzarini, J. (2004). Inactivity of the bicyclic pyrimidine nucle-oside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymi-dine kinase. Biochem. Biophys. Res. Commun., 315, 877-883.
    • (2004) Biochem. Biophys. Res. Commun , vol.315 , pp. 877-883
    • Sienaert, R.1    Andrei, G.2    Snoeck, R.3    De Clercq, E.4    Mc Guigan, C.5    Balzarini, J.6
  • 147
    • 0036157975 scopus 로고    scopus 로고
    • Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase
    • Sienaert, R., Naesens, L., Brancale, A., De Clercq, E., McGuigan, C., and Balzarini, J. (2002). Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase. Mol. Pharmacol., 61, 249-254.
    • (2002) Mol. Pharmacol , vol.61 , pp. 249-254
    • Sienaert, R.1    Naesens, L.2    Brancale, A.3    De Clercq, E.4    Mc Guigan, C.5    Balzarini, J.6
  • 148
    • 2442719000 scopus 로고    scopus 로고
    • Herpes simplex virus 1 U(L)31 and U(L)34 gene products pro-mote the late maturation of viral replication compartments to the nuclear periphery
    • Simpson-Holley, M., Baines, J., Roller, R., and Knipe, D. M. (2004). Herpes simplex virus 1 U(L)31 and U(L)34 gene products pro-mote the late maturation of viral replication compartments to the nuclear periphery. J. Virol., 78, 5591-5600.
    • (2004) J. Virol , vol.78 , pp. 5591-5600
    • Simpson-Holley, M.1    Baines, J.2    Roller, R.3    Knipe, D.M.4
  • 149
    • 0033013425 scopus 로고    scopus 로고
    • Indolocarbazoles: Potent, selective inhibitors of human cytomegalovirus repli-cation
    • Slater, M. J., Cockerill, S., Baxter, R. et al. (1999). Indolocarbazoles: Potent, selective inhibitors of human cytomegalovirus repli-cation. Bioorg. Med. Chem., 7, 1067-1074.
    • (1999) Bioorg. Med. Chem , vol.7 , pp. 1067-1074
    • Slater, M.J.1    Cockerill, S.2    Baxter, R.3
  • 150
    • 0024599635 scopus 로고
    • Identification of new protein kinase-related genes in three herpesviruses, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus
    • Smith, R. F. and Smith, T. F. (1989). Identification of new protein kinase-related genes in three herpesviruses, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus. J. Virol., 63, 450-455.
    • (1989) J. Virol , vol.63 , pp. 450-455
    • Smith, R.F.1    Smith, T.F.2
  • 151
    • 18644374841 scopus 로고    scopus 로고
    • 2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections
    • Snoeck, R., Andrei, G., Bodaghi, B. et al. (2002). 2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections. Antiviral Res., 55, 413-424.
    • (2002) Antiviral Res , vol.55 , pp. 413-424
    • Snoeck, R.1    Andrei, G.2    Bodaghi, B.3
  • 152
    • 0027245440 scopus 로고
    • Efficacy of (-)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine in African green monkeys infected with simian varicella virus
    • Soike, K. F., Bohm, R., Huang, J. L., and, Oberg, B. (1993). Efficacy of (-)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine in African green monkeys infected with simian varicella virus. Antimicrob. Agents Chemother., 37, 1370-1372.
    • (1993) Antimicrob. Agents Chemother , vol.37 , pp. 1370-1372
    • Soike, K.F.1    Bohm, R.2    Huang, J.L.3    Oberg, B.4
  • 153
    • 0031846516 scopus 로고    scopus 로고
    • Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex
    • Spector, F. C., Liang, L., Giordano, H., Sivaraja, M., and Peterson, M. G. (1998). Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex. J. Virol., 72, 6979-6987.
    • (1998) J. Virol , vol.72 , pp. 6979-6987
    • Spector, F.C.1    Liang, L.2    Giordano, H.3    Sivaraja, M.4    Peterson, M.G.5
  • 154
    • 0028925773 scopus 로고
    • Mechanism of inhibition of HIV-1 reverse transcrip-tase by nonnucleoside inhibitors
    • Spence, R. A., Kati, W. M., Anderson, K. S., and Johnson, K. A. (1995). Mechanism of inhibition of HIV-1 reverse transcrip-tase by nonnucleoside inhibitors. Science, 267, 988-993.
    • (1995) Science , vol.267 , pp. 988-993
    • Spence, R.A.1    Kati, W.M.2    Anderson, K.S.3    Johnson, K.A.4
  • 155
    • 0036241367 scopus 로고    scopus 로고
    • Open reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that con-tains a strong transcriptional activation domain
    • Stamminger, T., Gstaiger, M., Weinzierl, K., Lorz, K., Winkler, M., and Schaffner, W. (2002). Open reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that con-tains a strong transcriptional activation domain. J. Virol., 76, 4836-4847.
    • (2002) J. Virol , vol.76 , pp. 4836-4847
    • Stamminger, T.1    Gstaiger, M.2    Weinzierl, K.3    Lorz, K.4    Winkler, M.5    Schaffner, W.6
  • 156
    • 0027110881 scopus 로고
    • A protein kinase homologue controls phos-phorylation of ganciclovir in human cytomegalovirus-infected cells
    • Sullivan, V., Talarico, C. L., Stanat, S. C., Davis, M., Coen, D. M., and Biron, K. K. (1992). A protein kinase homologue controls phos-phorylation of ganciclovir in human cytomegalovirus-infected cells. Nature, 359, 85.
    • (1992) Nature , vol.359 , pp. 85
    • Sullivan, V.1    Talarico, C.L.2    Stanat, S.C.3    Davis, M.4    Coen, D.M.5    Biron, K.K.6
  • 157
    • 0041919643 scopus 로고    scopus 로고
    • Protease inhibitors of the sulfonamide type: Anticancer, antiinfiamma-tory, and antiviral agents
    • Supuran, C. T., Casini, A., and Scozzafava, A. (2003). Protease inhibitors of the sulfonamide type: Anticancer, antiinfiamma-tory, and antiviral agents. Med. Res. Rev., 23, 535-558.
    • (2003) Med. Res. Rev , vol.23 , pp. 535-558
    • Supuran, C.T.1    Casini, A.2    Scozzafava, A.3
  • 158
    • 0032838505 scopus 로고    scopus 로고
    • Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein
    • Talarico, C. L., Burnette, T. C., Miller, W. H. et al. (1999). Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein. Antimicrob. Agents Chemother., 43, 1941-1946.
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 1941-1946
    • Talarico, C.L.1    Burnette, T.C.2    Miller, W.H.3
  • 159
    • 0030734329 scopus 로고    scopus 로고
    • Lobu-cavir is phosphorylated in human cytomegalovirus-infected and-uninfected cells and inhibits the viral DNA polymerase
    • Tenney, D. J., Yamanaka, G., Voss, S. M. et al. (1997). Lobu-cavir is phosphorylated in human cytomegalovirus-infected and-uninfected cells and inhibits the viral DNA polymerase. Antimicrob. Agents Chemother., 41, 2680-2685.
    • (1997) Antimicrob. Agents Chemother , vol.41 , pp. 2680-2685
    • Tenney, D.J.1    Yamanaka, G.2    Voss, S.M.3
  • 160
    • 33746263661 scopus 로고    scopus 로고
    • Identification of the interaction domain of the small terminase subunit pUL89 with the large subunit pUL56 of human cytomegalovirus
    • Thoma, C., Borst, E., Messerle, M., Rieger, M., Hwang, J. S. and Bogner, E. (2006). Identification of the interaction domain of the small terminase subunit pUL89 with the large subunit pUL56 of human cytomegalovirus. Biochemistry, 45, 8855-8863.
    • (2006) Biochemistry , vol.45 , pp. 8855-8863
    • Thoma, C.1    Borst, E.2    Messerle, M.3    Rieger, M.4    Hwang, J.S.5    Bogner, E.6
  • 161
    • 0037303608 scopus 로고    scopus 로고
    • Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resis-tance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents
    • Thomsen, D. R., Oien, N. L., Hopkins, T. A. et al. (2003). Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resis-tance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents. J. Virol., 77, 1868-1876.
    • (2003) J. Virol , vol.77 , pp. 1868-1876
    • Thomsen, D.R.1    Oien, N.L.2    Hopkins, T.A.3
  • 162
    • 1842479742 scopus 로고    scopus 로고
    • Imiquimod and resiquimod in a mouse model: Adju-vants for DNA vaccination by particle-mediated immunother-apeutic delivery
    • Thomsen, L. L., Topley, P., Daly, M. G., Brett, S. J., and Tite, J. P. (2004). Imiquimod and resiquimod in a mouse model: Adju-vants for DNA vaccination by particle-mediated immunother-apeutic delivery. Vaccine, 22, 1799-1809.
    • (2004) Vaccine , vol.22 , pp. 1799-1809
    • Thomsen, L.L.1    Topley, P.2    Daly, M.G.3    Brett, S.J.4    Tite, J.P.5
  • 163
    • 0014803750 scopus 로고
    • Benzimidazole nucle-osides, nucleotides, and related derivatives
    • Townsend, L. B. and Revankar, G. R. (1970). Benzimidazole nucle-osides, nucleotides, and related derivatives. Chem. Rev., 70, 389-438.
    • (1970) Chem. Rev , vol.70 , pp. 389-438
    • Townsend, L.B.1    Revankar, G.R.2
  • 164
    • 0028853743 scopus 로고
    • Design, synthesis, and antiviral activity of certain 2,5,6-trihalo-l-(beta-D-ribofuranosyl)benzimidazoles
    • Townsend, L. B., Devivar, R. V., Turk, S. R., Nassiri, M. R., and Drach, J. C. (1995). Design, synthesis, and antiviral activity of certain 2,5,6-trihalo-l-(beta-D-ribofuranosyl)benzimidazoles. J. Med. Chem., 38, 4098-4105.
    • (1995) J. Med. Chem , vol.38 , pp. 4098-4105
    • Townsend, L.B.1    Devivar, R.V.2    Turk, S.R.3    Nassiri, M.R.4    Drach, J.C.5
  • 165
    • 0032989644 scopus 로고    scopus 로고
    • Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB
    • Townsend, L. B., Gudmundsson, K. S., Daluge, S. M. et al. (1999). Studies designed to increase the stability and antiviral activity (HCMV) of the active benzimidazole nucleoside, TCRB. Nucle-osides Nucleotides, 18, 509-519.
    • (1999) Nucle-osides Nucleotides , vol.18 , pp. 509-519
    • Townsend, L.B.1    Gudmundsson, K.S.2    Daluge, S.M.3
  • 166
    • 1842405464 scopus 로고    scopus 로고
    • Stud-ies of protein-protein interfaces: A statistical analysis of the hydrophobic effect
    • Tsai, C. J., Lin, S. L., Wolfson, H. J., and Nussinov, R. (1997). Stud-ies of protein-protein interfaces: A statistical analysis of the hydrophobic effect. Protein Sci., 6, 53-64.
    • (1997) Protein Sci , vol.6 , pp. 53-64
    • Tsai, C.J.1    Lin, S.L.2    Wolfson, H.J.3    Nussinov, R.4
  • 167
    • 0031985103 scopus 로고    scopus 로고
    • Inhibi-tion of human cytomegalovirus DNA maturation by a benz-imidazole ribonucleoside is mediated through the UL89 gene product
    • Underwood, M. R., Harvey, R. J., Stanat, S. C. et al. (1998). Inhibi-tion of human cytomegalovirus DNA maturation by a benz-imidazole ribonucleoside is mediated through the UL89 gene product. J. Virol., 72, 717-725.
    • (1998) J. Virol , vol.72 , pp. 717-725
    • Underwood, M.R.1    Harvey, R.J.2    Stanat, S.C.3
  • 168
    • 0033817586 scopus 로고    scopus 로고
    • Naph-thalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase
    • Vaillancourt, V. A., Cudahy, M. M., Staley, S. A. et al. (2000). Naph-thalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase. Bioorg. Med. Chem. Lett., 10, 2079-2081.
    • (2000) Bioorg. Med. Chem. Lett , vol.10 , pp. 2079-2081
    • Vaillancourt, V.A.1    Cudahy, M.M.2    Staley, S.A.3
  • 169
    • 0030955930 scopus 로고    scopus 로고
    • The human cytomegalovirus UL97 protein is phosphory lated and a component of virions
    • Van Zeijl, M., Fairhurst, J., Baum, E. Z., Sun, L., and Jones, T. R.(1997). The human cytomegalovirus UL97 protein is phosphory lated and a component of virions. Virology, 231, 72-80.
    • (1997) Virology , vol.231 , pp. 72-80
    • Van Zeijl, M.1    Fairhurst, J.2    Baum, E.Z.3    Sun, L.4    Jones, T.R.5
  • 170
    • 0033804501 scopus 로고    scopus 로고
    • Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: Resistance maps to the UL6 gene
    • van Zeijl, M., Fairhurst, J., Jones, T. R. et al. (2000). Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: Resistance maps to the UL6 gene. J. Virol., 74, 9054-9061.
    • (2000) J. Virol , vol.74 , pp. 9054-9061
    • Van Zeijl, M.1    Fairhurst, J.2    Jones, T.R.3
  • 171
    • 0042706429 scopus 로고    scopus 로고
    • DNA encapsidation as a tar-get for antiherpesvirus drug therapy
    • Visalli, R. J. and van Zeijl, M. (2003). DNA encapsidation as a tar-get for antiherpesvirus drug therapy. Antiviral Res., 59, 73-87.
    • (2003) Antiviral Res , vol.59 , pp. 73-87
    • Visalli, R.J.1    Van Zeijl, M.2
  • 172
    • 0037323134 scopus 로고    scopus 로고
    • Identification of small molecule compounds that selectively inhibit varicella-zoster virus replication
    • Visalli, R. J., Fairhurst, J., Srinivas, S. et al. (2003). Identification of small molecule compounds that selectively inhibit varicella-zoster virus replication. J. Virol., 77, 2349-2358.
    • (2003) J. Virol , vol.77 , pp. 2349-2358
    • Visalli, R.J.1    Fairhurst, J.2    Srinivas, S.3
  • 173
    • 0037378069 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic trials of 1263W94, a novel oral anti-human cytomegalovirus agent, in healthy and human immunodeficiency virus-infected subject
    • Wang, L. H., Peck, R. W., Yin, Y., Allanson, J., Wiggs, R., and Wire, M. W. (2003). Phase I safety and pharmacokinetic trials of 1263W94, a novel oral anti-human cytomegalovirus agent, in healthy and human immunodeficiency virus-infected subject. Antimicrob. Agents Chemother., 47, 1334-1342.
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 1334-1342
    • Wang, L.H.1    Peck, R.W.2    Yin, Y.3    Allanson, J.4    Wiggs, R.5    Wire, M.W.6
  • 174
    • 12944317148 scopus 로고    scopus 로고
    • Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cido-fovir against human and murine cytomegalovirus replication in vitro
    • Wan, W. B., Beadle, J. R., Hartline, C. et al. (2005). Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cido-fovir against human and murine cytomegalovirus replication in vitro. Antimicrob. Agents. Chemother., 49, 656-662.
    • (2005) Antimicrob. Agents. Chemother , vol.49 , pp. 656-662
    • Wan, W.B.1    Beadle, J.R.2    Hartline, C.3
  • 175
    • 0036093153 scopus 로고    scopus 로고
    • Non-nucleoside inhibitors of herpesviruses
    • Wathen, M. W. (2002). Non-nucleoside inhibitors of herpesviruses. Rev. Med. Virol., 12, 167-178.
    • (2002) Rev. Med. Virol , vol.12 , pp. 167-178
    • Wathen, M.W.1
  • 176
    • 0033972803 scopus 로고    scopus 로고
    • The herpesvirus proteases as targets for antiviral chemotherapy
    • Waxman, L. and Darke, P. L. (2000). The herpesvirus proteases as targets for antiviral chemotherapy. Antivir. Chem. Chemother., 11, 1-22.
    • (2000) Antivir. Chem. Chemother , vol.11 , pp. 1-22
    • Waxman, L.1    Darke, P.L.2
  • 177
    • 27644446403 scopus 로고    scopus 로고
    • The Toll-like receptor 7 (TLR7) ago-nist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vagi-nal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques
    • Wang, Y., Abel, K., Lantz, K., Krieg, A. M., McChesney, M. B., and Miller, C. J. (2005). The Toll-like receptor 7 (TLR7) ago-nist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vagi-nal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques. J. Virol., 79, 14355-14370.
    • (2005) J. Virol , vol.79 , pp. 14355-14370
    • Wang, Y.1    Abel, K.2    Lantz, K.3    Krieg, A.M.4    Mc Chesney, M.B.5    Miller, C.J.6
  • 178
    • 0035050725 scopus 로고    scopus 로고
    • Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleosidic compound in vivo
    • Weber, O., Bender, W., Eckenberg, P. et al. (2001). Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleosidic compound in vivo. Antiviral Res., 49, 179-189.
    • (2001) Antiviral Res , vol.49 , pp. 179-189
    • Weber, O.1    Bender, W.2    Eckenberg, P.3
  • 179
    • 0038027004 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 portal protein UL6 interacts with the putative terminase subunits UL15 and UL28
    • White, C. A., Stow, N. D., Patel, A. H., Hughes, M., and Preston, V. G. (2003). Herpes simplex virus type 1 portal protein UL6 interacts with the putative terminase subunits UL15 and UL28. J Virol., 77, 6351-6358.
    • (2003) J Virol , vol.77 , pp. 6351-6358
    • White, C.A.1    Stow, N.D.2    Patel, A.H.3    Hughes, M.4    Preston, V.G.5
  • 180
    • 0037974682 scopus 로고    scopus 로고
    • In vitro activities of benzimidazole D-and L-ribonucleosides against herpesviruses
    • Williams, S. L., Hartline, C. B., Kushner, N. L. et al. (2003). In vitro activities of benzimidazole D-and L-ribonucleosides against herpesviruses. Antimicrob. Agents Chemother., 47, 2186-2192.
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 2186-2192
    • Williams, S.L.1    Hartline, C.B.2    Kushner, N.L.3
  • 181
    • 24144458260 scopus 로고    scopus 로고
    • Com-parative activities of lipid esters of cidofovir and cyclic cido-fovir against replication of herpesviruses in vitro
    • Williams-Aziz, S. L., Hartline, C. B., Harden, E. A. et al. (2005). Com-parative activities of lipid esters of cidofovir and cyclic cido-fovir against replication of herpesviruses in vitro. Antimicrob. Agents Chemother., 49, 3724-3733.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 3724-3733
    • Williams-Aziz, S.L.1    Hartline, C.B.2    Harden, E.A.3
  • 182
    • 0035852743 scopus 로고    scopus 로고
    • Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsi-dation
    • Wolf, D. G., Courcelle, C. T., Prichard, M. N., and Mocarski, E. S. (2001). Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsi-dation. Proc. Natl Acad. Sci. USA, 98, 1895-1900.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1895-1900
    • Wolf, D.G.1    Courcelle, C.T.2    Prichard, M.N.3    Mocarski, E.S.4
  • 183
    • 0035852743 scopus 로고    scopus 로고
    • Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsi-dation
    • Wolf, D. G., Courcelle, C. T., Prichard, M. N., and Mocarski, E. S. (2001). Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsi-dation. Proc. Natl Acad. Sci. U.S.A, 98, 1895-1900.
    • (2001) Proc. Natl Acad. Sci. U.S.A , vol.98 , pp. 1895-1900
    • Wolf, D.G.1    Courcelle, C.T.2    Prichard, M.N.3    Mocarski, E.S.4
  • 184
    • 0032816076 scopus 로고    scopus 로고
    • Inhibition of Epstein-Barr virus replica-tion by a benzimidazole L-riboside: Novel antiviral mechanism of 5,6-dichloro-2-(isopropylamino)-1-beta-L-ribofuranosyl-1H-benzimidazole
    • Zacny, V. L., Gershburg, E., Davis, M. G., Biron, K. K., and Pagano, J. S. (1999). Inhibition of Epstein-Barr virus replica-tion by a benzimidazole L-riboside: Novel antiviral mechanism of 5,6-dichloro-2-(isopropylamino)-1-beta-L-ribofuranosyl-1H-benzimidazole. J Virol., 73, 7271-7277.
    • (1999) J Virol , vol.73 , pp. 7271-7277
    • Zacny, V.L.1    Gershburg, E.2    Davis, M.G.3    Biron, K.K.4    Pagano, J.S.5


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