Specific phosphorylation of exogenous protein and peptide substrates by the human cytomegalovirus UL97 protein kinase: Importance of the P+5 position

Journal of Biological Chemistry

Volumn 277, Issue 33, 2002, Pages 29593-29599

  Baek, Moon Chang ^a,b   Krosky, Paula M ^a,c   He, Zuwen ^a,d   Coen, Donald M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Gotham Networks   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DRUG DOSAGE; ENZYME KINETICS; GELS; KETONES; SUBSTRATES;

FUSION PROTEIN; GLUTATHIONE; PHOSPHORYLATION; PROTEIN KINASE;

ENZYMES;

ARGININE; BENZIMIDAVIR; HISTONE H2B; LYSINE; PROTEIN KINASE; PROTEIN UL97; SERINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; HISTONE; IMMEDIATE EARLY PROTEIN; PEPTIDE; PROTEIN; UL98 PROTEIN, CYTOMEGALOVIRUS;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME SPECIFICITY; HUMAN CYTOMEGALOVIRUS; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; ANIMAL; ARMYWORM; CELL LINE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION;

HUMAN HERPESVIRUS 5;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; HISTONES; IMMEDIATE-EARLY PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHORYLATION; PROTEINS; SPODOPTERA; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

EID: 0037119463     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202312200     Document Type: Article

References (44)

1. Taylor, S. S., Radzio-Andzelm, E., and Hunter, T. (1995) FASEB J. 9, 1255-1266
2. Johnson, L. N., Noble, M. E. M., and Owen, D. J. (1996) Cell 85, 149-158
3. Johnson, L. N., Lowe, E. D., Noble, M. E. M., and Owen, D. J. (1998) FEBS Lett. 430, 1-11
4. Littler, E., Stuart, A. D., and Chee, M. S. (1992) Nature 358, 160-162
5. Sullivan, V., Talarico, C. L., Stanat, S. C., Davis, M., Coen, D. M., and Biron, K. K. (1992) Nature 358, 162-164
6. Talarico, C. L., Burnette, T. C., Miller, W. H., Smith, S. L., Davis, M. G., Stanat, S. C., Ng, T. I., He, Z., Coen, D. M., Roizman, B., and Biron, K. K. (1999) Antimicrob. Agents Chemother. 43, 1941-1946
7. McGeoch, D. J., Coulter, L. J., and Moss, H. W. M. (1995) in The Protein Kinase Facts Book (Hardie, G., and Hanks, S., eds) Vol. 1, pp. 391-393, Academic Press, London
8. de Wind, N., Domen, J., and Berns, A. (1992) J. Virol. 66, 5200-5209
9. Smith, R. F., and Smith, T. F. (1989) J. Virol. 63, 450-455
10. Chee, M. S., Lawrence, G. L., and Barrell, B. G. (1989) J. Gen. Virol. 70, 1151-1160
11. He, Z., He, Y.-S., Kim, Y., Chu, L., Ohmstede, C., Biron, K. K., and Coen, D. M. (1997) J. Virol. 71, 405-411
12. Prichard, M. N., Gao, N., Jairath, S., Mulamba, G., Krosky, P., Coen, D. M., Parker, B. O., and Pari, G. S. (1999) J. Virol. 73, 5663-5670
13. Biron, K. K., Harvey, R. J., Chamberlain, S. C., Good, S. S., Smith, A. A., Davis, M. G., Talarico, C. L., Ferris, R., Dornsife, R. E., Stanat, S. C., Drach, J. C., Townsend, L. B., and Koszalka, G. W. (2002) Antimicrob. Agents Chemother. 45, in press
14. Wolf, D. G., Courcelle, C. T., Prichard, M. N., and Mocarski, E. S. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 1895-1900
15. Purves, F. C., Ogle, W. O., and Roizman, B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6701-6705
16. Crossen, R., and Gruenwald, S. (1998) Baculovirus Expression Vector System Manual, 5th Ed., Pharmingen, San Diego
17. Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. (1996) Anal. Chem. 68, 850-858
18. Dadd, C. A., Cook, R. G., and Allis, C. D. (1993) BioTechniques 14, 266-273
19. Mizzen, C. A., Dou, Y., Liu, Y., Cook, R. G., Gorovsky, M. A., and Allis, C. D. (1999) J. Biol. Chem. 274, 14533-14536
20. West, M. H. P., Wu, R. S., and Bonner, W. M. (1984) Electrophoresis 5, 133-138
21. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., pp. 18.47-18.53, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
22. Hanks, S. K., and Hunter, T. (1995) FASEB J. 9, 576-596
23. Glass, D. B., Masaracchia, R. A., Feramisco, J. R., and Kemp, B. E. (1978) Anal. Biochem. 87, 566-575
24. Glass, D. B., and Krebs, E. G. (1979) J. Biol. Chem. 254, 9728-9738
25. Glass, D. B., and Krebs, E. G. (1982) J. Biol. Chem. 257, 1196-1200
26. Hashimoto, E., Takeda, M., and Nishizuka, Y. (1976) J. Biol. Chem. 251, 6287-6293
27. Glass, D. B., Cheng, H.-C., Kemp, B. E., and Walsh, D. A. (1986) J. Biol. Chem. 261, 12166-12171
28. Glass, D. B., Cheng, H.-C., Mende-Muller, L., Reed, J., and Walsh, D. A. (1989) J. Biol. Chem. 264, 8802-8810
29. Ng, T. I., and Grose, C. (1992) Virology 191, 9-18
30. Daikoku, T., Shibata, S., Goshima, F., Oshima, S., Tsurumi, T., Yamada, H., Yamashita, Y., and Nishiyama, Y. (1997) Virology 235, 82-93
31. Ansari, A., and Emery, V. C. (1999) J. Virol. 73, 3284-3291
32. Chen, M.-R., Chang, S.-J., Huang, H., and Chen, J.-Y. (2000) J. Virol. 74, 3093-3104
33. Kenyon, T. K., Lynch, J., Hay, J., Ruyechan, W., and Grose, C. (2001) J. Virol. 75, 8854-8858
34. Michel, D., Pavic, I., Zimmermann, A., Haupt, E., Wunderlich, K., Heuschmid, M., and Mertens, T. (1996) J. Virol. 70, 6340-6346
35. van Zeijl, M., Fairhurst, J., Baum, E. Z., Sun, L., and Jones, T. R. (1997) Virology 231, 72-80
36. Mocarski, E. S., and Courcelle, C. T. (2001) in Fields Virology (Knipe, D. M., Howley, P. M., Griffin, D. E., Lamb, R. A., Martin, M. A., Roizman, B., and Straus, S. E., eds) Vol. 2, 4th Ed., pp. 2629-2673, Lippincott Williams & Wilkins, Philadelphia
37. Roizman, B., and Furlong, D. (1974) in Comprehensive Virology (Fraenkel-Contrat, H., and Wagner, R. R., eds) pp. 229-403, Plenum, New York
38. Jenuwein, T., and Allis, C. D. (2001) Science 293, 1074-1080
39. Songyang, Z., Blechner, S., Hoagland, N., Hoekstra, M. F., Piwnica-Worms, H., and Cantley, L. C. (1994) Curr. Biol. 4, 973-982
40. Pearson, R. B., and Kemp, B. E. (1991) Methods Enzymol. 200, 62-81
41. Kemp, B. E., Graves, D. J., Benjamini, E., and Krebs, E. G. (1977) J. Biol. Chem. 252, 4888-4894
42. Songyang, Z., Lu, K P., Kwon, Y. T., Tsai, L.-H., Filhol, O., Cochet, C., Brickey, D. A., Soderling, T. R., Bartleson, C., Graves, D. J., Demaggio, A. J., Hoekstra, M. F., Blenis, J., Hunter, T., and Cantley, L. C. (1996) Mol. Cell. Biol. 16, 6486-6493
43. Nishikawa, K., Sawasdikosol, S., Fruman, D. A., Lai, J., Songyang, Z., Burakoff, S. J., Yaffe, M. B., and Cantley, L. C. (2000) Mol. Cell 6, 969-974
44. Roberts, N. A., Martin, J. A., Kinchington, D., Broadhurst, A. V., Craig, J. C., Duncan, I. B., Galpin, S. A., Handa, B. K., Kay, J., Krohn, A., Lambert, R. W., Merrett, J. H., Mills, J. S., Parkes, K. E. B., Redshaw, S., et al. (1990) Science 248, 358-361