Mode of action of (1'S,2'R)-9-{[1',2'-Bis(hydroxymethyl) cycloprop-1'- yl]methyl}guanine (A-5021) against herpes simplex virus type 1 and type 2 and varicella-zoster virus

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 8, 1998, Pages 2095-2102

  Ono, Nobukazu ^a,b   Iwayama, Satoshi ^a   Suzuki, Katsuya ^a   Sekiyama, Takaaki ^a   Nakazawa, Harumi ^a   Tsuji, Takashi ^a   Okunishi, Masahiko ^a   Daikoku, Tohru ^b   Nishiyama, Yukihiro ^b  

^a AJINOMOTO CO INC   (Japan)

^b Department of Breast and Endocrine Surgery Aichi Medical School of Medicine   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

9 [1,2 BIS(HYDROXYMETHYL)CYCLOPROPYLMETHYL]GUANINE; ACICLOVIR; DNA POLYMERASE; GUANOSINE DERIVATIVE; PENCICLOVIR; THYMIDINE KINASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACCUMULATION; DRUG HALF LIFE; DRUG MECHANISM; ENZYME INHIBITION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; VARICELLA ZOSTER VIRUS; VIRUS INFECTION;

EID: 0031904278     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.8.2095     Document Type: Article

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