Broad-spectrum antiherpes activities of 4-hydroxyquinoline carboxamides, a novel class of herpesvirus polymerase inhibitors

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 3, 2002, Pages 724-730

  Oien, Nancee L ^a   Brideau, Roger J ^a   Hopkins, Todd A ^a   Wieber, Janet L ^a   Knechtel, Mary L ^a   Shelly, John A ^a   Anstadt, Robert A ^a   Wells, Peter A ^a   Poorman, Roger A ^a   Huang, Audris ^a   Vaillancourt, Vallerie A ^a   Clayton, Terrance L ^a   Tucker, John A ^a   Wathen, Michael W ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYQUINOLINE CARBOXAMIDE DERIVATIVE; ANTIVIRUS AGENT; DNA POLYMERASE; ENZYME INHIBITOR; GANCICLOVIR; HERPES VIRUS POLYMERASE; NAPHTHALENE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ENZYME; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; HERPES SIMPLEX VIRUS 1; HUMAN CYTOMEGALOVIRUS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN FAMILY; STRUCTURE ACTIVITY RELATION; VARICELLA ZOSTER VIRUS; VIRUS REPLICATION;

AMIDES; ANTIVIRAL AGENTS; BINDING, COMPETITIVE; CELL SURVIVAL; CELLS, CULTURED; DNA-DIRECTED DNA POLYMERASE; ENZYME INHIBITORS; HERPESVIRIDAE; HUMANS; HYDROXYQUINOLINES; KINETICS; PLAQUE ASSAY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0036167879     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.3.724-730.2002     Document Type: Article

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