Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses

Antiviral Research

Volumn 54, Issue 1, 2002, Pages 19-28

  Brideau, Roger J ^a   Knechtel, Mary L ^a   Huang, Audris ^a   Vaillancourt, Valerie A ^a   Vera, Ellen E ^a   Oien, Nancee L ^a   Hopkins, Todd A ^a   Wieber, Janet L ^a   Wilkinson, Karen F ^a   Rush, Bob D ^a   Schwende, Francis J ^a   Wathen, Michael W ^a  

^a PFIZER INC   (United States)

Author keywords

Antiviral activity; Dihydroquinoline; DNA polymerases; Herpesviruses; PNU 183792

Indexed keywords

4 OXO DIHYDROQUINOLINE DERIVATIVE; ACICLOVIR; ANTIVIRUS AGENT; CIDOFOVIR; DNA DIRECTED DNA POLYMERASE ALPHA; GANCICLOVIR; PNU 183792; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENZYME; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DOG; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SPECIFICITY; ENZYME INHIBITION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IC 50; MONKEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SIMIAN VIRUS; VARICELLA ZOSTER VIRUS; VERO CELL; VIRUS CULTURE; VIRUS PLAQUE; VIRUS RESISTANCE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, VIRAL; ENZYME INHIBITORS; HERPESVIRIDAE; HERPESVIRIDAE INFECTIONS; HUMANS; MICE; MICE, INBRED BALB C; MUROMEGALOVIRUS; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; CANINE DISTEMPER VIRUS; CERCOPITHECINE HERPESVIRUS 9; CYTOMEGALOVIRUS; HERPESVIRIDAE; HUMAN HERPESVIRUS 3; HUMAN HERPESVIRUS 5; MAIZE CHLOROTIC MOTTLE VIRUS; MAMMALIA; MOUSE CYTOMEGALOVIRUS 1; MURINAE; RAT CYTOMEGALOVIRUS; RNA VIRUSES; SIMIAE; SIMPLEXVIRUS;

EID: 18344373269     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(01)00208-X     Document Type: Article

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