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Volumn 43, Issue 8, 1999, Pages 1941-1946

Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; GANCICLOVIR;

EID: 0032838505     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.8.1941     Document Type: Article
Times cited : (84)

References (47)
  • 1
    • 0028885224 scopus 로고
    • A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate
    • Baldanti, F., E. Silini, A. Sarasini, C. L. Talarico, S. C. Stanat, K. K. Biron, M. Furione, F. Bono, G. Palu, and G. Gerna. 1995. A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate. J. Virol. 69:796-800.
    • (1995) J. Virol. , vol.69 , pp. 796-800
    • Baldanti, F.1    Silini, E.2    Sarasini, A.3    Talarico, C.L.4    Stanat, S.C.5    Biron, K.K.6    Furione, M.7    Bono, F.8    Palu, G.9    Gerna, G.10
  • 2
    • 0031594747 scopus 로고    scopus 로고
    • The Cys607→Tyr change in the UL97 phosphotransferase confers ganciclovir resistance to two human cytomegalovirus strains recovered from two immunocompromised patients
    • Baldanti, F., M. R. Underwood, C. L. Talarico, L. Simoncini, A. Sarasini, K. K. Biron, and G. Gerna. 1998. The Cys607→Tyr change in the UL97 phosphotransferase confers ganciclovir resistance to two human cytomegalovirus strains recovered from two immunocompromised patients. Antimicrob. Agents. Chemother. 42:444-446.
    • (1998) Antimicrob. Agents. Chemother. , vol.42 , pp. 444-446
    • Baldanti, F.1    Underwood, M.R.2    Talarico, C.L.3    Simoncini, L.4    Sarasini, A.5    Biron, K.K.6    Gerna, G.7
  • 3
    • 0024361608 scopus 로고
    • A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allographs
    • Balfour, H. H., Jr., B. A. Chace, J. T. Stapleton, R. L. Simmons, and D. S. Fryd. 1989. A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allographs. N. Engl. J. Med. 320:1381-1387.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1381-1387
    • Balfour H.H., Jr.1    Chace, B.A.2    Stapleton, J.T.3    Simmons, R.L.4    Fryd, D.S.5
  • 4
    • 0021807545 scopus 로고
    • Metabolic activation of the nucleoside analog 9-{[2-hydroxyl-1-(hydroxymethyl)ethoxy]methyl} guanine in human diploid fibroblasts infected with human cytomegalovirus
    • Biron, K. K., S. C. Stanat, J. B. Sorrell, J. A. Fyfe, P. M. Keller, C. U. Lambe, and D. J. Nelson. 1985. Metabolic activation of the nucleoside analog 9-{[2-hydroxyl-1-(hydroxymethyl)ethoxy]methyl} guanine in human diploid fibroblasts infected with human cytomegalovirus. Proc. Natl. Acad. Sci. USA 82:2473-2477.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2473-2477
    • Biron, K.K.1    Stanat, S.C.2    Sorrell, J.B.3    Fyfe, J.A.4    Keller, P.M.5    Lambe, C.U.6    Nelson, D.J.7
  • 5
    • 2742573036 scopus 로고
    • A human cytomegalovirus mutant resistant to the nucleoside analog 9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl} guanine (BW B759U) induces reduced levels of BW B759U triphosphate
    • Biron, K. K., J. A. Fyfe, S. C. Stanat, L. K. Leslie, J. B. Sorrell, C. U. Lambe, and D. M. Coen. 1986. A human cytomegalovirus mutant resistant to the nucleoside analog 9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl} guanine (BW B759U) induces reduced levels of BW B759U triphosphate. Proc. Natl. Acad. Sci. USA 83:8769-3773.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8769-13773
    • Biron, K.K.1    Fyfe, J.A.2    Stanat, S.C.3    Leslie, L.K.4    Sorrell, J.B.5    Lambe, C.U.6    Coen, D.M.7
  • 6
    • 0021739206 scopus 로고
    • Phosphorylation of the antiviral precursor 9-(1,3-dihydroxy-2-propoxymethyl)guanine monophosphate by guanylate kinase isozymes
    • Boehme, R. 1984. Phosphorylation of the antiviral precursor 9-(1,3-dihydroxy-2-propoxymethyl)guanine monophosphate by guanylate kinase isozymes. J. Biol. Chem. 259:12346-12349.
    • (1984) J. Biol. Chem. , vol.259 , pp. 12346-12349
    • Boehme, R.1
  • 7
    • 0024599231 scopus 로고
    • Alpha-, beta-, and gammaherpesviruses encode a putative phosphotransferase
    • Chee, M. S., G. L. Lawrence, and B. G. Barrell. 1989. Alpha-, beta-, and gammaherpesviruses encode a putative phosphotransferase. J. Gen. Microbiol. 70:1151-1160.
    • (1989) J. Gen. Microbiol. , vol.70 , pp. 1151-1160
    • Chee, M.S.1    Lawrence, G.L.2    Barrell, B.G.3
  • 8
    • 0021055765 scopus 로고
    • Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells
    • Cheng, Y. C., S. P, Grill, G. E. Dutschman, K. Nakayama, and K. F. Bastow. 1983. Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells. J. Biol. Chem. 258:12460-12464.
    • (1983) J. Biol. Chem. , vol.258 , pp. 12460-12464
    • Cheng, Y.C.1    Grill, S.P.2    Dutschman, G.E.3    Nakayama, K.4    Bastow, K.F.5
  • 9
    • 0028940302 scopus 로고
    • Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance
    • Chou, S. C., A. Erice, M. C. Jordan, G. M. Vercellotti, K. R. Michels, C. L. Talarico, S. C. Stanat, and K. K. Biron. 1995. Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance. J. Infect. Dis. 171:576-583.
    • (1995) J. Infect. Dis. , vol.171 , pp. 576-583
    • Chou, S.C.1    Erice, A.2    Jordan, M.C.3    Vercellotti, G.M.4    Michels, K.R.5    Talarico, C.L.6    Stanat, S.C.7    Biron, K.K.8
  • 10
    • 0023281112 scopus 로고
    • In vitro susceptibility of cytomegalovirus isolates from immunocompromised patients to acyclovir and ganciclovir
    • Cole, N. L., and H. H. Balfour, Jr. 1987. In vitro susceptibility of cytomegalovirus isolates from immunocompromised patients to acyclovir and ganciclovir. Diagn. Microbiol. Infect. Dis. 6:255-261.
    • (1987) Diagn. Microbiol. Infect. Dis. , vol.6 , pp. 255-261
    • Cole, N.L.1    Balfour H.H., Jr.2
  • 11
    • 0028963950 scopus 로고
    • Failure of high-dose oral acyclovir to suppress CMV viruria or induce ganciclovir-resistant CMV in HIV antibody positive patients
    • Drew, W. L., R. Anderson, W. Lang, R. C. Miner, G. Davis, and J. Lalezari. 1995. Failure of high-dose oral acyclovir to suppress CMV viruria or induce ganciclovir-resistant CMV in HIV antibody positive patients. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 8:289-291.
    • (1995) J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. , vol.8 , pp. 289-291
    • Drew, W.L.1    Anderson, R.2    Lang, W.3    Miner, R.C.4    Davis, G.5    Lalezari, J.6
  • 12
    • 0024028676 scopus 로고
    • Herpesvirus infections (cytomegalovirus, herpes simplex virus, varicella zoster virus). How to use ganciclovir (DHPG) and acyclovir
    • Drew, W. L., W. Buhles, and K. S. Erlich. 1988. Herpesvirus infections (cytomegalovirus, herpes simplex virus, varicella zoster virus). How to use ganciclovir (DHPG) and acyclovir. Infect. Dis. Clin. N. Am. 2:495-509.
    • (1988) Infect. Dis. Clin. N. Am. , vol.2 , pp. 495-509
    • Drew, W.L.1    Buhles, W.2    Erlich, K.S.3
  • 16
    • 0028905944 scopus 로고
    • A comparative study of the in vitro and in vivo antiviral activities of acyclovir and penciclovir
    • Ertl, P., W. Snowden, D. Lowe, W. Miller, P. Collins, and E. Littler. 1995. A comparative study of the in vitro and in vivo antiviral activities of acyclovir and penciclovir. Antivir. Chem. Chemother. 6:89-97.
    • (1995) Antivir. Chem. Chemother. , vol.6 , pp. 89-97
    • Ertl, P.1    Snowden, W.2    Lowe, D.3    Miller, W.4    Collins, P.5    Littler, E.6
  • 19
    • 0018733296 scopus 로고
    • Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate
    • Furman, P. A., M. H. St. Clair, J. A. Fyfe, J. L. Rideout, P. M. Keller, and G. B. Elion. 1979. Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate. J. Virol. 32:72-77.
    • (1979) J. Virol. , vol.32 , pp. 72-77
    • Furman, P.A.1    St. Clair, M.H.2    Fyfe, J.A.3    Rideout, J.L.4    Keller, P.M.5    Elion, G.B.6
  • 21
    • 0018251481 scopus 로고
    • Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine
    • Fyfe, J. A., P. M. Keller, P. A. Furman, R. L. Miller, and G. B. Elion. 1978. Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine. J. Biol. Chem. 253:8721-8727.
    • (1978) J. Biol. Chem. , vol.253 , pp. 8721-8727
    • Fyfe, J.A.1    Keller, P.M.2    Furman, P.A.3    Miller, R.L.4    Elion, G.B.5
  • 22
    • 0019644374 scopus 로고
    • Cytomegalovirus infections following renal transplantation
    • Glenn, J. 1981. Cytomegalovirus infections following renal transplantation. Rev. Infect. Dis. 3:1151-1178.
    • (1981) Rev. Infect. Dis. , vol.3 , pp. 1151-1178
    • Glenn, J.1
  • 23
    • 0031985193 scopus 로고    scopus 로고
    • The effect of valaciclovir on cytomegalovirus viremia and viruria detected by polymerase chain reaction in patients with advanced human immunodeficiency virus disease
    • Griffiths, P. D., J. E. Feinberg, J. Fry, C. Sabin, L. Dix, D. Gor, A. Ansari, and V. C. Emery. 1998. The effect of valaciclovir on cytomegalovirus viremia and viruria detected by polymerase chain reaction in patients with advanced human immunodeficiency virus disease. J. Infect. Dis. 177:57-64.
    • (1998) J. Infect. Dis. , vol.177 , pp. 57-64
    • Griffiths, P.D.1    Feinberg, J.E.2    Fry, J.3    Sabin, C.4    Dix, L.5    Gor, D.6    Ansari, A.7    Emery, V.C.8
  • 24
    • 0025228048 scopus 로고
    • Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination
    • Hamzeh, F. M., P. S. Lietman, W. Gibson, and G. S. Hayward. 1990. Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination. J. Virol. 64:6184-6195.
    • (1990) J. Virol. , vol.64 , pp. 6184-6195
    • Hamzeh, F.M.1    Lietman, P.S.2    Gibson, W.3    Hayward, G.S.4
  • 25
    • 0029040849 scopus 로고
    • Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir
    • Hanson, M. N., L. C. Preheim, S. C. Chou, C. L. Talarico, K. K. Biron, and A. Erice. 1995. Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir. Antimicrob. Agents Chemother. 39:1204-1205.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1204-1205
    • Hanson, M.N.1    Preheim, L.C.2    Chou, S.C.3    Talarico, C.L.4    Biron, K.K.5    Erice, A.6
  • 26
    • 0344193223 scopus 로고    scopus 로고
    • Personal communication
    • He, Z., and D. M. Coen. Personal communication.
    • He, Z.1    Coen, D.M.2
  • 27
    • 0031060542 scopus 로고    scopus 로고
    • The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines
    • He, Z., Y.-S. He, Y. Kim, L. Chu, C. Ohmstede, K. K. Biron, and D. M. Coen. 1997. The human cytomegalovirus UL97 protein is a protein kinase that autophosphorylates on serines and threonines. J. Virol. 71:405-411.
    • (1997) J. Virol. , vol.71 , pp. 405-411
    • He, Z.1    He, Y.-S.2    Kim, Y.3    Chu, L.4    Ohmstede, C.5    Biron, K.K.6    Coen, D.M.7
  • 29
    • 0022350376 scopus 로고
    • Cytoplasmic 5′-nucleotidase catalyzes acyclovir phosphorylation
    • Keller, P. M., S. A. McKee, and J. A. Fyfe. 1985. Cytoplasmic 5′-nucleotidase catalyzes acyclovir phosphorylation. J. Biol. Chem. 260:8664-8667.
    • (1985) J. Biol. Chem. , vol.260 , pp. 8664-8667
    • Keller, P.M.1    McKee, S.A.2    Fyfe, J.A.3
  • 30
    • 0026664424 scopus 로고
    • The human cytomegalovirus UL97 open reading frame encodes a protein which phosphorylates the antiviral nucleoside analogue ganciclovir
    • Littler, E., A. D. Stuart, and M. S. Chee. 1992. The human cytomegalovirus UL97 open reading frame encodes a protein which phosphorylates the antiviral nucleoside analogue ganciclovir. Nature 358:160-162.
    • (1992) Nature , vol.358 , pp. 160-162
    • Littler, E.1    Stuart, A.D.2    Chee, M.S.3
  • 31
    • 0028271126 scopus 로고
    • Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir
    • Lurain, N. S., L. E. Spafford, and K. D. Thompson. 1994. Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir. J. Virol. 68:4427-4431.
    • (1994) J. Virol. , vol.68 , pp. 4427-4431
    • Lurain, N.S.1    Spafford, L.E.2    Thompson, K.D.3
  • 32
    • 0020573744 scopus 로고
    • Effect of 9-(1,3-dihydroxy-2-proxymethyl) guanine on human cytomegalovirus replication in vitro
    • Mar, E-C., Y-C. Cheng, and E-S. Huang. 1983. Effect of 9-(1,3-dihydroxy-2-proxymethyl) guanine on human cytomegalovirus replication in vitro. Antimicrob. Agents Chemother. 24:518-521.
    • (1983) Antimicrob. Agents Chemother. , vol.24 , pp. 518-521
    • Mar, E.-C.1    Cheng, Y.-C.2    Huang, E.-S.3
  • 33
    • 0019478851 scopus 로고
    • Cytomegalovirus infection: A quantitative prospective study of three hundred twenty consecutive renal transplants
    • Marker, S. C., R. J. Howard, R. I. Simmons, et al. 1981. Cytomegalovirus infection: a quantitative prospective study of three hundred twenty consecutive renal transplants. Surgery 89:660-671.
    • (1981) Surgery , vol.89 , pp. 660-671
    • Marker, S.C.1    Howard, R.J.2    Simmons, R.I.3
  • 34
    • 0019925472 scopus 로고
    • Acyclovir inhibition of viral DNA chain elongation in herpes simplex virus-infected cells
    • McQuirt, P. V., and P. A. Furman. 1982. Acyclovir inhibition of viral DNA chain elongation in herpes simplex virus-infected cells. Am. J. Med. 73 (Suppl. 1A):67-71.
    • (1982) Am. J. Med. , vol.73 , Issue.SUPPL. 1A , pp. 67-71
    • McQuirt, P.V.1    Furman, P.A.2
  • 35
    • 0028051525 scopus 로고
    • Human cytomegalovirus UL97 kinase confers ganciclovir susceptibility to recombinant vaccinia virus
    • Metzger, C., D. Michel, K. Schneider, A. Lüske, H.-J. Schlicht, and T. Mertens. 1994. Human cytomegalovirus UL97 kinase confers ganciclovir susceptibility to recombinant vaccinia virus. J. Virol. 68:8423-8427.
    • (1994) J. Virol. , vol.68 , pp. 8423-8427
    • Metzger, C.1    Michel, D.2    Schneider, K.3    Lüske, A.4    Schlicht, H.-J.5    Mertens, T.6
  • 36
    • 0023873331 scopus 로고
    • Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation
    • Meyers, J. D., E. C. Reed, D. H. Shepp, et al. 1988. Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation. N. Engl. J. Med. 318:70-75.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 70-75
    • Meyers, J.D.1    Reed, E.C.2    Shepp, D.H.3
  • 37
    • 0029841220 scopus 로고    scopus 로고
    • The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase
    • Michel, D., I. Pavic, A. Zimmerman, E. Haupt, K. Wunderlich, M. Heuschmid, and T. Mertens. 1996. The UL97 gene product of human cytomegalovirus is an early-late protein with a nuclear localization but is not a nucleoside kinase. J. Virol. 70:6340-6346.
    • (1996) J. Virol. , vol.70 , pp. 6340-6346
    • Michel, D.1    Pavic, I.2    Zimmerman, A.3    Haupt, E.4    Wunderlich, K.5    Heuschmid, M.6    Mertens, T.7
  • 38
    • 0030588936 scopus 로고    scopus 로고
    • Partial substitution of the functions of the herpes simplex virus 1 UL13 gene by the human cytomegalovirus UL97 gene
    • Ng, T. I., C. Talarico, T. C. Burnette, K. Biron, and B. Roizman. 1996. Partial substitution of the functions of the herpes simplex virus 1 UL13 gene by the human cytomegalovirus UL97 gene. Virology 225:347-358.
    • (1996) Virology , vol.225 , pp. 347-358
    • Ng, T.I.1    Talarico, C.2    Burnette, T.C.3    Biron, K.4    Roizman, B.5
  • 39
    • 0021227981 scopus 로고
    • Parenteral acyclovir therapy for cytomegalovirus infection after renal transplantation
    • Nunan, T. O., M. King, P. Bull, J. E. Banatvala, N. F. Jones, and P. J. Hilton. 1984. Parenteral acyclovir therapy for cytomegalovirus infection after renal transplantation. Clin. Nephrol. 22:28-31.
    • (1984) Clin. Nephrol. , vol.22 , pp. 28-31
    • Nunan, T.O.1    King, M.2    Bull, P.3    Banatvala, J.E.4    Jones, N.F.5    Hilton, P.J.6
  • 40
    • 0018896452 scopus 로고
    • Cytomegalovirus disease in renal allograft recipients: A prospective study of the clinical features, risk factors and impact on renal transplantation
    • Peterson, P. K., H. H. Balfour, S. C. Marker, D. S. Fryd, R. J. Howard, and R. L. Simmons. 1980. Cytomegalovirus disease in renal allograft recipients: a prospective study of the clinical features, risk factors and impact on renal transplantation. Medicine 59:283-300.
    • (1980) Medicine , vol.59 , pp. 283-300
    • Peterson, P.K.1    Balfour, H.H.2    Marker, S.C.3    Fryd, D.S.4    Howard, R.J.5    Simmons, R.L.6
  • 41
    • 0026009379 scopus 로고
    • Suppression of cytomegalovirus retinitis in persons with AIDS with high-dose intravenous acyclovir
    • Sha, B. E., C. A. Benson, T. A. Deutsch, P. A. Urbanski, J. P. Phair, and H. A. Kessler. 1991. Suppression of cytomegalovirus retinitis in persons with AIDS with high-dose intravenous acyclovir. J. Infect. Dis. 164:777-780.
    • (1991) J. Infect. Dis. , vol.164 , pp. 777-780
    • Sha, B.E.1    Benson, C.A.2    Deutsch, T.A.3    Urbanski, P.A.4    Phair, J.P.5    Kessler, H.A.6
  • 42
    • 0020614981 scopus 로고
    • Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine
    • Smee, D. F., J. C. Martin, J. P. Verheyden, and T. R. Matthews. 1983. Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine. Antimicrob. Agents Chemother. 23:676-682.
    • (1983) Antimicrob. Agents Chemother. , vol.23 , pp. 676-682
    • Smee, D.F.1    Martin, J.C.2    Verheyden, J.P.3    Matthews, T.R.4
  • 43
    • 0029762282 scopus 로고    scopus 로고
    • Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro
    • Snoeck, R., G. Andrei, and E. De Clercq. 1996. Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro. Eur. J. Clin. Microbiol. Infect. Dis. 15:574-579.
    • (1996) Eur. J. Clin. Microbiol. Infect. Dis. , vol.15 , pp. 574-579
    • Snoeck, R.1    Andrei, G.2    De Clercq, E.3
  • 45
    • 0025992797 scopus 로고
    • Isolation of foscarnet-resistant human cytomegalovirus: Patterns of resistance and sensitivity to other antiviral drugs
    • Sullivan, V., and D. M. Coen. 1991. Isolation of foscarnet-resistant human cytomegalovirus: patterns of resistance and sensitivity to other antiviral drugs. J. Infect. Dis. 164:781-784.
    • (1991) J. Infect. Dis. , vol.164 , pp. 781-784
    • Sullivan, V.1    Coen, D.M.2
  • 46
    • 0026720227 scopus 로고
    • A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
    • Sullivan, V., C. L. Talarico, S. C. Stanat, M. Davis, D. M. Coen, and K. K. Biron. 1992. A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells. Nature 358:162-164.
    • (1992) Nature , vol.358 , pp. 162-164
    • Sullivan, V.1    Talarico, C.L.2    Stanat, S.C.3    Davis, M.4    Coen, D.M.5    Biron, K.K.6
  • 47
    • 0030782932 scopus 로고    scopus 로고
    • Phosphorylation of acyclovir, ganciclovir, penciclovir, and S2242 by the cytomegalovirus UL97 protein: A quantitative analysis using recombinant vaccinia viruses
    • Zimmermann, A., D. Michel, I. Pavic, W. Hampl, A. Luske, J. Neyts, E. De Clercq, and T. Mertens. 1997. Phosphorylation of acyclovir, ganciclovir, penciclovir, and S2242 by the cytomegalovirus UL97 protein: a quantitative analysis using recombinant vaccinia viruses. Antivir. Res. 36:35-42.
    • (1997) Antivir. Res. , vol.36 , pp. 35-42
    • Zimmermann, A.1    Michel, D.2    Pavic, I.3    Hampl, W.4    Luske, A.5    Neyts, J.6    De Clercq, E.7    Mertens, T.8


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