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Volumn 46, Issue 8, 2002, Pages 2373-2380
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Preclinical and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication
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Author keywords
[No Author keywords available]
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Indexed keywords
BENZIMIDAVIR;
ANTIVIRUS AGENT;
BENZIMIDAZOLE DERIVATIVE;
PLASMA PROTEIN;
RIBONUCLEOSIDE;
AMES TEST;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ARTICLE;
BILIARY EXCRETION;
BLOOD BRAIN BARRIER;
CONTROLLED STUDY;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG CEREBROSPINAL FLUID LEVEL;
DRUG CLEARANCE;
DRUG DISTRIBUTION;
DRUG EXCRETION;
DRUG METABOLISM;
DRUG PROTEIN BINDING;
DRUG SAFETY;
DRUG STRUCTURE;
DRUG TISSUE LEVEL;
ENTEROHEPATIC CIRCULATION;
FEMALE;
GENETIC TOXICOLOGY;
HEPATOMEGALY;
HUMAN CYTOMEGALOVIRUS;
MALE;
MICRONUCLEUS TEST;
MINIMUM INHIBITORY CONCENTRATION;
MONKEY;
MOUSE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
TOXICOLOGY;
VIRUS INHIBITION;
VIRUS REPLICATION;
ANIMAL;
AREA UNDER THE CURVE;
BIOTRANSFORMATION;
CYTOMEGALOVIRUS;
DOG;
DRUG EFFECT;
HALF LIFE TIME;
HUMAN;
INTRAVENOUS DRUG ADMINISTRATION;
MACACA;
METABOLISM;
MUTAGEN TESTING;
ORAL DRUG ADMINISTRATION;
PROTEIN BINDING;
SPRAGUE DAWLEY RAT;
TISSUE DISTRIBUTION;
WISTAR RAT;
ADMINISTRATION, ORAL;
ANIMAL;
ANTIVIRAL AGENTS;
AREA UNDER CURVE;
BENZIMIDAZOLES;
BIOTRANSFORMATION;
BLOOD PROTEINS;
CYTOMEGALOVIRUS;
DOGS;
FEMALE;
HALF-LIFE;
HUMAN;
INJECTIONS, INTRAVENOUS;
MACACA FASCICULARIS;
MALE;
MICE;
MUTAGENICITY TESTS;
PROTEIN BINDING;
RATS;
RATS, SPRAGUE-DAWLEY;
RATS, WISTAR;
RIBONUCLEOSIDES;
TISSUE DISTRIBUTION;
ANIMALS;
HUMANS;
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EID: 0035991712
PISSN: 00664804
EISSN: None
Source Type: Journal
DOI: 10.1128/AAC.46.8.2373-2380.2002 Document Type: Article |
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Times cited : (86)
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References (20)
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