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Volumn 3, Issue , 2014, Pages e186-

The CRISPR/Cas9 system facilitates clearance of the intrahepatic HBV templates in vivo

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN; COVALENTLY CLOSED CIRCULAR DNA; GUIDE RNA; MEMBRANE ANTIGEN; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

EID: 84907379292     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2014.38     Document Type: Article
Times cited : (337)

References (40)
  • 1
    • 0034234540 scopus 로고    scopus 로고
    • Increased hepatocyte turnover and inhibition of woodchuck hepatitis b virus replication by adefovir in vitro do not lead to reduction of the closed circular dna
    • Dandri, M, Burda, MR, Will, H and Petersen, J (2000). Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA. Hepatology 32: 139-146.
    • (2000) Hepatology , vol.32 , pp. 139-146
    • Dandri, M.1    Burda, M.R.2    Will, H.3    Petersen, J.4
  • 2
    • 0030776176 scopus 로고    scopus 로고
    • Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular dna of woodchuck hepatitis virus
    • Moraleda, G, Saputelli, J, Aldrich, CE, Averett, D, Condreay, L and Mason, WS (1997). Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus. J Virol 71: 9392-9399.
    • (1997) J Virol , vol.71 , pp. 9392-9399
    • Moraleda, G.1    Saputelli, J.2    Aldrich, C.E.3    Averett, D.4    Condreay, L.5    Mason, W.S.6
  • 3
    • 0033029334 scopus 로고    scopus 로고
    • Biphasic clearance kinetics of hepatitis b virus from patients during adefovir dipivoxil therapy
    • Tsiang, M, Rooney, JF, Toole, JJ and Gibbs, CS (1999). Biphasic clearance kinetics of hepatitis B virus from patients during adefovir dipivoxil therapy. Hepatology 29: 1863-1869.
    • (1999) Hepatology , vol.29 , pp. 1863-1869
    • Tsiang, M.1    Rooney, J.F.2    Toole, J.J.3    Gibbs, C.S.4
  • 4
    • 2942532722 scopus 로고    scopus 로고
    • Persistence of cccdna during the natural history of chronic hepatitis b and decline during adefovir dipivoxil therapy
    • Werle-Lapostolle, B, Bowden, S, Locarnini, S, Wursthorn, K, Petersen, J, Lau, G, et al. (2004). Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy. Gastroenterology 126: 1750-1758.
    • (2004) Gastroenterology , vol.126 , pp. 1750-1758
    • Werle-Lapostolle, B.1    Bowden, S.2    Locarnini, S.3    Wursthorn, K.4    Petersen, J.5    Lau, G.6
  • 5
    • 29744468790 scopus 로고    scopus 로고
    • Cccdna persistence during natural evolution of chronic vhb infection
    • Caruntu, FA and Molagic, V (2005). CccDNA persistence during natural evolution of chronic VHB infection. Rom J Gastroenterol 14: 373-377.
    • (2005) Rom J Gastroenterol , vol.14 , pp. 373-377
    • Caruntu, F.A.1    Molagic, V.2
  • 6
    • 20444505037 scopus 로고    scopus 로고
    • Intrahepatic hepatitis b virus covalently closed circular dna can be a predictor of sustained response to therapy
    • Sung, JJ, Wong, ML, Bowden, S, Liew, CT, Hui, AY, Wong, VW et al. (2005). Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy. Gastroenterology 128: 1890-1897.
    • (2005) Gastroenterology , vol.128 , pp. 1890-1897
    • Sung, J.J.1    Wong, M.L.2    Bowden, S.3    Liew, C.T.4    Hui, A.Y.5    Wong, V.W.6
  • 7
    • 84880799657 scopus 로고    scopus 로고
    • Predictors of hepatitis b cure using gene therapy to deliver dna cleavage enzymes: A mathematical modeling approach
    • Schiffer, JT, Swan, DA, Stone, D and Jerome, KR (2013). Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach. PLoS Comput Biol 9: e1003131.
    • (2013) PLoS Comput Biol , vol.9
    • Schiffer, J.T.1    Swan, D.A.2    Stone, D.3    Jerome, K.R.4
  • 8
    • 77952011493 scopus 로고    scopus 로고
    • Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis b virus dnas
    • Cradick, TJ, Keck, K, Bradshaw, S, Jamieson, AC and McCaffrey, AP (2010). Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs. Mol Ther 18: 947-954.
    • (2010) Mol Ther , vol.18 , pp. 947-954
    • Cradick, T.J.1    Keck, K.2    Bradshaw, S.3    Jamieson, A.C.4    McCaffrey, A.P.5
  • 9
    • 84885023096 scopus 로고    scopus 로고
    • Inactivation of hepatitis b virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases
    • Bloom, K, Ely, A, Mussolino, C, Cathomen, T and Arbuthnot, P (2013). Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases. Mol Ther 21: 1889-1897.
    • (2013) Mol Ther , vol.21 , pp. 1889-1897
    • Bloom, K.1    Ely, A.2    Mussolino, C.3    Cathomen, T.4    Arbuthnot, P.5
  • 10
    • 84895908706 scopus 로고    scopus 로고
    • An efficient antiviral strategy for targeting hepatitis b virus genome using transcription activator-like effector nucleases
    • Chen, J, Zhang, W, Lin, J, Wang, F, Wu, M, Chen, C et al. (2014). An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases. Mol Ther 22: 303-311.
    • (2014) Mol Ther , vol.22 , pp. 303-311
    • Chen, J.1    Zhang, W.2    Lin, J.3    Wang, F.4    Wu, M.5    Chen, C.6
  • 12
    • 84879264708 scopus 로고    scopus 로고
    • Zfn talen and crispr/cas-based methods for genome engineering
    • Gaj, T, Gersbach, CA and Barbas, CF 3rd (2013). ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 31: 397-405.
    • (2013) Trends Biotechnol , vol.31 , pp. 397-405
    • Gaj, T.1    Gersbach, C.A.2    Barbas III, C.F.3
  • 13
    • 84882449996 scopus 로고    scopus 로고
    • Biological and biomedical applications of engineered nucleases
    • Pan, Y, Xiao, L, Li, AS, Zhang, X, Sirois, P, Zhang, J et al. (2013). Biological and biomedical applications of engineered nucleases. Mol Biotechnol 55: 54-62.
    • (2013) Mol Biotechnol , vol.55 , pp. 54-62
    • Pan, Y.1    Xiao, L.2    Li, A.S.3    Zhang, X.4    Sirois, P.5    Zhang, J.6
  • 14
    • 77957935381 scopus 로고    scopus 로고
    • Crispr/cas system and its role in phage-bacteria interactions
    • Deveau, H, Garneau, JE and Moineau, S (2010). CRISPR/Cas system and its role in phage-bacteria interactions. Annu Rev Microbiol 64: 475-493.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 475-493
    • Deveau, H.1    Garneau, J.E.2    Moineau, S.3
  • 15
    • 80755187812 scopus 로고    scopus 로고
    • Crispr-cas systems in bacteria and archaea: Versatile small rnas for adaptive defense and regulation
    • Bhaya, D, Davison, M and Barrangou, R (2011). CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation. Annu Rev Genet 45: 273-297.
    • (2011) Annu Rev Genet , vol.45 , pp. 273-297
    • Bhaya, D.1    Davison, M.2    Barrangou, R.3
  • 17
    • 84857097177 scopus 로고    scopus 로고
    • Rna-guided genetic silencing systems in bacteria and archaea
    • Wiedenheft, B, Sternberg, SH and Doudna, JA (2012). RNA-guided genetic silencing systems in bacteria and archaea. Nature 482: 331-338.
    • (2012) Nature , vol.482 , pp. 331-338
    • Wiedenheft, B.1    Sternberg, S.H.2    Doudna, J.A.3
  • 18
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-rna-guided dna endonuclease in adaptive bacterial immunity
    • Jinek, M, Chylinski, K, Fonfara, I, Hauer, M, Doudna, JA and Charpentier, E (2012). A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337: 816-821.
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 20
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using crispr/cas systems
    • Cong, L, Ran, FA, Cox, D, Lin, S, Barretto, R, Habib, N et al. (2013). Multiplex genome engineering using CRISPR/Cas systems. Science 339: 819-823.
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1    Ran, F.A.2    Cox, D.3    Lin, S.4    Barretto, R.5    Habib, N.6
  • 21
    • 84874624936 scopus 로고    scopus 로고
    • Targeted genome engineering in human cells with the cas9 rna-guided endonuclease
    • Cho, SW, Kim, S, Kim, JM and Kim, JS (2013). Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat Biotechnol 31: 230-232.
    • (2013) Nat Biotechnol , vol.31 , pp. 230-232
    • Cho, S.W.1    Kim, S.2    Kim, J.M.3    Kim, J.S.4
  • 25
    • 84884943528 scopus 로고    scopus 로고
    • Targeted heritable mutation and gene conversion by cas9-crispr in caenorhabditis elegans
    • Katic, I and Großhans, H (2013). Targeted heritable mutation and gene conversion by Cas9-CRISPR in Caenorhabditis elegans. Genetics 195: 1173-1176.
    • (2013) Genetics , vol.195 , pp. 1173-1176
    • Katic, I.1    Großhans, H.2
  • 26
    • 84877707375 scopus 로고    scopus 로고
    • Onestep generation of mice carrying mutations in multiple genes by crispr/cas-mediated genome engineering
    • Wang, H, Yang, H, Shivalila, CS, Dawlaty, MM, Cheng, AW, Zhang, F et al. (2013). Onestep generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153: 910-918.
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1    Yang, H.2    Shivalila, C.S.3    Dawlaty, M.M.4    Cheng, A.W.5    Zhang, F.6
  • 27
    • 78149319907 scopus 로고    scopus 로고
    • Generation of covalently closed circular dna of hepatitis b viruses via intracellular recycling is regulated in a virus specific manner
    • Köck, J, Rösler, C, Zhang, JJ, Blum, HE, Nassal, M and Thoma, C (2010). Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner. PLoS Pathog 6: e1001082.
    • (2010) PLoS Pathog , vol.6
    • Köck, J.1    Rösler, C.2    Zhang, J.J.3    Blum, H.E.4    Nassal, M.5    Thoma, C.6
  • 28
    • 84983721048 scopus 로고    scopus 로고
    • An immunocompetent mouse model for the tolerance of human chronic hepatitis b virus infection
    • Huang, LR, Wu, HL, Chen, PJ and Chen, DS (2006). An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection. Proc Natl Acad Sci USA 103: 17862-17867.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17862-17867
    • Huang, L.R.1    Wu, H.L.2    Chen, P.J.3    Chen, D.S.4
  • 29
    • 84879315928 scopus 로고    scopus 로고
    • Blocking the natural killer cell inhibitory receptor nkg2a increases activity of human natural killer cells and clears hepatitis b virus infection in mice
    • Li, F, Wei, H, Wei, H, Gao, Y, Xu, L, Yin, W et al. (2013). Blocking the natural killer cell inhibitory receptor NKG2A increases activity of human natural killer cells and clears hepatitis B virus infection in mice. Gastroenterology 144: 392-401.
    • (2013) Gastroenterology , vol.144 , pp. 392-401
    • Li, F.1    Wei, H.2    Wei, H.3    Gao, Y.4    Xu, L.5    Yin, W.6
  • 30
    • 84891710947 scopus 로고    scopus 로고
    • Analysis of off-target effects of crispr/cas-derived rna-guided endonucleases and nickases
    • Cho, SW, Kim, S, Kim, Y, Kweon, J, Kim, HS, Bae, S et al. (2014). Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res 24: 132-141.
    • (2014) Genome Res , vol.24 , pp. 132-141
    • Cho, S.W.1    Kim, S.2    Kim, Y.3    Kweon, J.4    Kim, H.S.5    Bae, S.6
  • 31
    • 84880570576 scopus 로고    scopus 로고
    • Highfrequency off-target mutagenesis induced by crispr-cas nucleases in human cells
    • Fu, Y, Foden, JA, Khayter, C, Maeder, ML, Reyon, D, Joung, JK et al. (2013). Highfrequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat Biotechnol 31: 822-826.
    • (2013) Nat Biotechnol , vol.31 , pp. 822-826
    • Fu, Y.1    Foden, J.A.2    Khayter, C.3    Maeder, M.L.4    Reyon, D.5    Joung, J.K.6
  • 32
    • 84884288934 scopus 로고    scopus 로고
    • Double nicking by rna-guided crispr cas9 for enhanced genome editing specificity
    • Ran, FA, Hsu, PD, Lin, CY, Gootenberg, JS, Konermann, S, Trevino, AE et al. (2013). Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154: 1380-1389.
    • (2013) Cell , vol.154 , pp. 1380-1389
    • Ran, F.A.1    Hsu, P.D.2    Lin, C.Y.3    Gootenberg, J.S.4    Konermann, S.5    Trevino, A.E.6
  • 33
    • 84884160273 scopus 로고    scopus 로고
    • Cas9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
    • Mali, P, Aach, J, Stranges, PB, Esvelt, KM, Moosburner, M, Kosuri, S et al. (2013). CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat Biotechnol 31: 833-838.
    • (2013) Nat Biotechnol , vol.31 , pp. 833-838
    • Mali, P.1    Aach, J.2    Stranges, P.B.3    Esvelt, K.M.4    Moosburner, M.5    Kosuri, S.6
  • 35
    • 84901648428 scopus 로고    scopus 로고
    • High-efficiency targeted editing of large viral genomes by rna-guided nucleases
    • Bi, Y, Sun, L, Gao, D, Ding, C, Li, Z, Li, Y et al. (2014). High-efficiency targeted editing of large viral genomes by RNA-guided nucleases. PLoS Pathog 10: e1004090.
    • (2014) PLoS Pathog , vol.10
    • Bi, Y.1    Sun, L.2    Gao, D.3    Ding, C.4    Li, Z.5    Li, Y.6
  • 36
    • 84883305437 scopus 로고    scopus 로고
    • Harnessing the crispr/cas9 system to disrupt latent hiv-1 provirus
    • Ebina, H, Misawa, N, Kanemura, Y and Koyanagi, Y (2013). Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus. Sci Rep 3: 2510.
    • (2013) Sci Rep , vol.3 , pp. 2510
    • Ebina, H.1    Misawa, N.2    Kanemura, Y.3    Koyanagi, Y.4
  • 37
    • 0014202537 scopus 로고
    • Selective extraction of polyoma dna from infected mouse cell cultures
    • Hirt, B (1967). Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol 26: 365-369.
    • (1967) J Mol Biol , vol.26 , pp. 365-369
    • Hirt, B.1
  • 38
    • 84876352590 scopus 로고    scopus 로고
    • Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases
    • Zhu, C, Gupta, A, Hall, VL, Rayla, AL, Christensen, RG, Dake, B et al. (2013). Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases. Nucleic Acids Res 41: 2455-2465.
    • (2013) Nucleic Acids Res , vol.41 , pp. 2455-2465
    • Zhu, C.1    Gupta, A.2    Hall, V.L.3    Rayla, A.L.4    Christensen, R.G.5    Dake, B.6
  • 40
    • 0021111829 scopus 로고
    • The complete nucleotide sequences of the cloned hepatitis b virus dna; subtype adr and adw
    • Ono, Y, Onda, H, Sasada, R, Igarashi, K, Sugino, Y and Nishioka, K (1983). The complete nucleotide sequences of the cloned hepatitis B virus DNA; subtype adr and adw. Nucleic Acids Res 11: 1747-1757.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1747-1757
    • Ono, Y.1    Onda, H.2    Sasada, R.3    Igarashi, K.4    Sugino, Y.5    Nishioka, K.6


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