AAV-mediated gene targeting is significantly enhanced by transient inhibition of nonhomologous end joining or the proteasome in vivo

Human Gene Therapy

Volumn 23, Issue 6, 2012, Pages 658-665

  Paulk, Nicole K ^a   Loza, Laura Marquez ^a   Finegold, Milton J ^b   Grompe, Markus ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; DNA DEPENDENT PROTEIN KINASE; PROTEASOME; VANILLIN;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA END JOINING REPAIR; FEMALE; GENE FREQUENCY; GENE MUTATION; GENE TARGETING; IN VIVO STUDY; LIVER TOXICITY; MALE; MOUSE; NEWBORN; NONHUMAN; SEX DIFFERENCE; TARGETED GENE REPAIR; TYROSINEMIA;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZALDEHYDES; BORONIC ACIDS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; DNA END-JOINING REPAIR; GENE TARGETING; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZINES; RECOMBINANT PROTEINS;

ADENO-ASSOCIATED VIRUS; MUS;

EID: 84864360337     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2012.038     Document Type: Article

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