An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level

Science

Volumn 342, Issue 6155, 2013, Pages 253-257

  Bauer, Daniel E ^a,b,c   Kamran, Sophia C ^c,d   Lessard, Samuel ^e   Xu, Jian ^a,c   Fujiwara, Yuko ^a   Lin, Carrie ^a   Shao, Zhen ^a   Canver, Matthew C ^c   Smith, Elenoe C ^a   Pinello, Luca ^b   Sabo, Peter J ^f   Vierstra, Jeff ^f   Voit, Richard A ^g   Yuan, Guo Cheng ^b,h   Porteus, Matthew H ^g   Stamatoyannopoulos, John A ^f   Lettre, Guillaume ^e   Orkin, Stuart H ^a,b,c,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e MONTREAL HEART INSTITUTE   (Canada)

^f UNIVERSITY OF WASHINGTON   (United States)

^g STANFORD UNIVERSITY   (United States)

^h HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN F; PROTEIN; PROTEIN BCL 11 A; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

DISEASE TREATMENT; DNA; EMBRYO; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC VARIATION; GENOME; HEMOGLOBIN;

ANIMAL CELL; ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC ENGINEERING; GENETIC VARIABILITY; LYMPHOID CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION;

EID: 84885620722     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1242088     Document Type: Article

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