-
1
-
-
84892430376
-
-
Joint united nation programme on HIV/AIDS (UNAIDS), WHO library cataloguing-in-publication data
-
UNAIDS. Reports on the global AIDS epidemic. Joint united nation programme on HIV/AIDS (UNAIDS), WHO library cataloguing-in-publication data. 2013
-
(2013)
Reports on the Global AIDS Epidemic
-
-
UNAIDS.1
-
2
-
-
79959301474
-
Safety and efficacy of the HVTN 503/ Phambili study of a clade-B-based HIV-1 vaccine in South Africa: A double-blind, randomised, placebo-controlled test-of-concept phase 2b study
-
Gray GE, Allen M, Moodie Z, et al. Safety and efficacy of the HVTN 503/ Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study. Lancet Infect Dis 2011;11:507-15
-
(2011)
Lancet Infect Dis
, vol.11
, pp. 507-515
-
-
Gray, G.E.1
Allen, M.2
Moodie, Z.3
-
3
-
-
84887865083
-
Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine
-
Hammer SM, Sobieszczyk ME, Janes H, et al. Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine. N Engl J Med 2013;369:2083-92
-
(2013)
N Engl J Med
, vol.369
, pp. 2083-2092
-
-
Hammer, S.M.1
Sobieszczyk, M.E.2
Janes, H.3
-
4
-
-
84878981012
-
Barriers to a cure for HIV: New ways to target and eradicate HIV-1 reservoirs
-
Katlama C, Deeks SG, Autran B, et al. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet 2013;381:2109-17
-
(2013)
Lancet
, vol.381
, pp. 2109-2117
-
-
Katlama, C.1
Deeks, S.G.2
Autran, B.3
-
5
-
-
84860345691
-
Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: A randomized 48-week study
-
Llibre JM, Buzon MJ, Massanella M, et al. Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study. Antivir Ther 2012;17:355-64
-
(2012)
Antivir Ther
, vol.17
, pp. 355-364
-
-
Llibre, J.M.1
Buzon, M.J.2
Massanella, M.3
-
6
-
-
40549100332
-
Overcoming resistance to existing therapies in HIV-infected patients: The role of new antiretroviral drugs
-
Perno CF, Moyle G, Tsoukas C, et al. Overcoming resistance to existing therapies in HIV-infected patients: the role of new antiretroviral drugs. J Med Virol 2008;80:565-76
-
(2008)
J Med Virol
, vol.80
, pp. 565-576
-
-
Perno, C.F.1
Moyle, G.2
Tsoukas, C.3
-
7
-
-
78650881417
-
Allogeneic transplantation of CCR5-deficient progenitor cells in a patient with HIV infection: An update after 3 years and the search for patient no. 2
-
Hutter G, Thiel E. Allogeneic transplantation of CCR5-deficient progenitor cells in a patient with HIV infection: an update after 3 years and the search for patient no. 2. AIDS 2011;25:273-4
-
(2011)
AIDS
, vol.25
, pp. 273-274
-
-
Hutter, G.1
Thiel, E.2
-
8
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
Hutter G, Nowak D, Mossner M, et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009;360:692-8
-
(2009)
N Engl J Med
, vol.360
, pp. 692-698
-
-
Hutter, G.1
Nowak, D.2
Mossner, M.3
-
9
-
-
84891772031
-
Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection
-
Didigu CA, Wilen CB, Wang J, et al. Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection. Blood 2014;123(1):61-9
-
(2014)
Blood
, vol.123
, Issue.1
, pp. 61-69
-
-
Didigu, C.A.1
Wilen, C.B.2
Wang, J.3
-
10
-
-
84901919285
-
CD4(+) T cells modified by the endoribonuclease MazF are safe and can persist in SHIV-infected rhesus macaques
-
Saito N, Chono H, Shibata H, et al. CD4(+) T cells modified by the endoribonuclease MazF are safe and can persist in SHIV-infected rhesus macaques. Mol Ther Nucleic Acids 2014;3:e168
-
(2014)
Mol Ther Nucleic Acids
, vol.3
, pp. e168
-
-
Saito, N.1
Chono, H.2
Shibata, H.3
-
11
-
-
84895487305
-
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
-
Tebas P, Stein D, Tang WW, et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med 2014;370:901-10
-
(2014)
N Engl J Med
, vol.370
, pp. 901-910
-
-
Tebas, P.1
Stein, D.2
Tang, W.W.3
-
12
-
-
78049429450
-
Computational models of HIV-1 resistance to gene therapy elucidate therapy design principles
-
Aviran S, Shah PS, Schaffer DV, Arkin AP. Computational models of HIV-1 resistance to gene therapy elucidate therapy design principles. PLoS Comput Biol 2010;6
-
(2010)
PLoS Comput Biol
, vol.6
-
-
Aviran, S.1
Shah, P.S.2
Schaffer, D.V.3
Arkin, A.P.4
-
13
-
-
79952653986
-
HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells
-
Carter CC, McNamara LA, Onafuwa-Nuga A, et al. HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells. Cell Host Microbe 2011;9:223-34
-
(2011)
Cell Host Microbe
, vol.9
, pp. 223-234
-
-
Carter, C.C.1
McNamara, L.A.2
Onafuwa-Nuga, A.3
-
14
-
-
84885018977
-
Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease
-
Sergijenko A, Langford-Smith A, Liao AY, et al. Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease. Mol Ther 2013;21:1938-49
-
(2013)
Mol Ther
, vol.21
, pp. 1938-1949
-
-
Sergijenko, A.1
Langford-Smith, A.2
Liao, A.Y.3
-
15
-
-
62049083710
-
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells
-
Mitsuyasu RT, Merigan TC, Carr A, et al. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells. Nat Med 2009;15:285-92
-
(2009)
Nat Med
, vol.15
, pp. 285-292
-
-
Mitsuyasu, R.T.1
Merigan, T.C.2
Carr, A.3
-
16
-
-
73249133305
-
Mathematical modelling of the impact of haematopoietic stem cell-delivered gene therapy for HIV
-
Murray JM, Fanning GC, MacPherson JL, et al. Mathematical modelling of the impact of haematopoietic stem cell-delivered gene therapy for HIV. J Gene Med 2009;11:1077-86
-
(2009)
J Gene Med
, vol.11
, pp. 1077-1086
-
-
Murray, J.M.1
Fanning, G.C.2
MacPherson, J.L.3
-
17
-
-
84903388914
-
A quantitative comparison of anti-HIV gene therapy delivered to hematopoietic stem cells versus CD4+ T cells
-
Savkovic B, Nichols J, Birkett D, et al. A quantitative comparison of anti-HIV gene therapy delivered to hematopoietic stem cells versus CD4+ T cells. PLoS Comput Biol 2014;10:e1003681
-
(2014)
PLoS Comput Biol
, vol.10
, pp. e1003681
-
-
Savkovic, B.1
Nichols, J.2
Birkett, D.3
-
18
-
-
57349118383
-
Control of HIV-1 immune escape by CD8 T cells expressing enhanced Tcell receptor
-
Varela-Rohena A, Molloy PE, Dunn SM, et al. Control of HIV-1 immune escape by CD8 T cells expressing enhanced Tcell receptor. Nat Med 2008;14:1390-5
-
(2008)
Nat Med
, vol.14
, pp. 1390-1395
-
-
Varela-Rohena, A.1
Molloy, P.E.2
Dunn, S.M.3
-
19
-
-
40149106131
-
Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity
-
Joseph A, Zheng JH, Follenzi A, et al. Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity. J Virol 2008;82:3078-89
-
(2008)
J Virol
, vol.82
, pp. 3078-3089
-
-
Joseph, A.1
Zheng, J.H.2
Follenzi, A.3
-
20
-
-
70349342731
-
Adoptive immunotherapy for cancer: The next generation of gene-engineered immune cells
-
Berry LJ, Moeller M, Darcy PK. Adoptive immunotherapy for cancer: the next generation of gene-engineered immune cells. Tissue Antigens 2009;74:277-89
-
(2009)
Tissue Antigens
, vol.74
, pp. 277-289
-
-
Berry, L.J.1
Moeller, M.2
Darcy, P.K.3
-
21
-
-
77952236875
-
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
-
Bendle GM, Linnemann C, Hooijkaas AI, et al. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med 2010;16:565-70.1p
-
(2010)
Nat Med
, vol.16
-
-
Bendle, G.M.1
Linnemann, C.2
Hooijkaas, A.I.3
-
22
-
-
18344406935
-
Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection
-
Walker RE, Bechtel CM, Natarajan V, et al. Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection. Blood 2000;96:467-74
-
(2000)
Blood
, vol.96
, pp. 467-474
-
-
Walker, R.E.1
Bechtel, C.M.2
Natarajan, V.3
-
23
-
-
0034254611
-
Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4 (+) and CD8(+) T cells in human immunodeficiency virus-infected subjects
-
Mitsuyasu RT, Anton PA, Deeks SG, et al. Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4 (+) and CD8(+) T cells in human immunodeficiency virus-infected subjects. Blood 2000;96:785-93
-
(2000)
Blood
, vol.96
, pp. 785-793
-
-
Mitsuyasu, R.T.1
Anton, P.A.2
Deeks, S.G.3
-
24
-
-
84877030619
-
Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression
-
Vatakis DN, Arumugam B, Kim SG, et al. Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression. Mol Ther 2013;21:1055-63
-
(2013)
Mol Ther
, vol.21
, pp. 1055-1063
-
-
Vatakis, D.N.1
Arumugam, B.2
Kim, S.G.3
-
25
-
-
0024299563
-
Gene therapy. Intracellular immunization
-
Baltimore D. Gene therapy. Intracellular immunization. Nature 1988;335:395-6
-
(1988)
Nature
, vol.335
, pp. 395-396
-
-
Baltimore, D.1
-
26
-
-
0024382709
-
Functional dissection of the HIV-1 Rev trans-activator - derivation of a trans-dominant repressor of Rev function
-
Malim MH, Bohnlein S, Hauber J, Cullen BR. Functional dissection of the HIV-1 Rev trans-activator - derivation of a trans-dominant repressor of Rev function. Cell 1989;58:205-14
-
(1989)
Cell
, vol.58
, pp. 205-214
-
-
Malim, M.H.1
Bohnlein, S.2
Hauber, J.3
Cullen, B.R.4
-
27
-
-
0026661059
-
Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication
-
Malim MH, Freimuth WW, Liu J, et al. Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication. J Exp Med 1992;176:1197-201
-
(1992)
J Exp Med
, vol.176
, pp. 1197-1201
-
-
Malim, M.H.1
Freimuth, W.W.2
Liu, J.3
-
28
-
-
33845994066
-
Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication
-
Bahner I, Sumiyoshi T, Kagoda M, et al. Lentiviral vector transduction of a dominant-negative Rev gene into human CD34+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication. Mol Ther 2007;15:76-85
-
(2007)
Mol Ther
, vol.15
, pp. 76-85
-
-
Bahner, I.1
Sumiyoshi, T.2
Kagoda, M.3
-
29
-
-
24944441656
-
Preferential survival of CD4+ T lymphocytes engineered with anti-human immunodeficiency virus (HIV) genes in HIV-infected individuals
-
Morgan RA, Walker R, Carter CS, et al. Preferential survival of CD4+ T lymphocytes engineered with anti-human immunodeficiency virus (HIV) genes in HIV-infected individuals. Hum Gene Ther 2005;16:1065-74
-
(2005)
Hum Gene Ther
, vol.16
, pp. 1065-1074
-
-
Morgan, R.A.1
Walker, R.2
Carter, C.S.3
-
30
-
-
0032477912
-
Enhanced T cell engraftment after retroviral delivery of an antiviral gene in HIV-infected individuals
-
Ranga U, Woffendin C, Verma S, et al. Enhanced T cell engraftment after retroviral delivery of an antiviral gene in HIV-infected individuals. Proc Natl Acad Sci USA 1998;95:1201-6
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1201-1206
-
-
Ranga, U.1
Woffendin, C.2
Verma, S.3
-
31
-
-
84875454096
-
A mutant Tat protein provides strong protection from HIV-1 infection in human CD4+ T cells
-
Apolloni A, Lin MH, Sivakumaran H, et al. A mutant Tat protein provides strong protection from HIV-1 infection in human CD4+ T cells. Hum Gene Ther 2013;24:270-82
-
(2013)
Hum Gene Ther
, vol.24
, pp. 270-282
-
-
Apolloni, A.1
Lin, M.H.2
Sivakumaran, H.3
-
32
-
-
0031963348
-
Inhibition of HIV-1 replication by combined expression of gag dominant negative mutant and a human ribonuclease in a tightly controlled HIV-1 inducible vector
-
Cara A, Rybak SM, Newton DL, et al. Inhibition of HIV-1 replication by combined expression of gag dominant negative mutant and a human ribonuclease in a tightly controlled HIV-1 inducible vector. Gene Ther 1998;5:65-75
-
(1998)
Gene Ther
, vol.5
, pp. 65-75
-
-
Cara, A.1
Rybak, S.M.2
Newton, D.L.3
-
33
-
-
0024443873
-
HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus
-
Trono D, Feinberg MB, Baltimore D. HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus. Cell 1989;59:113-20
-
(1989)
Cell
, vol.59
, pp. 113-120
-
-
Trono, D.1
Feinberg, M.B.2
Baltimore, D.3
-
34
-
-
65349148559
-
The F12-Vif derivative Chim3 inhibits HIV-1 replication in CD4+ T lymphocytes and CD34+-derived macrophages by blocking HIV-1 DNA integration
-
Porcellini S, Alberici L, Gubinelli F, et al. The F12-Vif derivative Chim3 inhibits HIV-1 replication in CD4+ T lymphocytes and CD34+-derived macrophages by blocking HIV-1 DNA integration. Blood 2009;113:3443-52
-
(2009)
Blood
, vol.113
, pp. 3443-3452
-
-
Porcellini, S.1
Alberici, L.2
Gubinelli, F.3
-
35
-
-
77951460356
-
Identification of dominant negative human immunodeficiency virus type 1 Vif mutants that interfere with the functional inactivation of APOBEC3G by virus-encoded Vif
-
Walker RC Jr, Khan MA, Kao S, et al. Identification of dominant negative human immunodeficiency virus type 1 Vif mutants that interfere with the functional inactivation of APOBEC3G by virus-encoded Vif. J Virol 2010;84:5201-11
-
(2010)
J Virol
, vol.84
, pp. 5201-5211
-
-
Walker, R.C.1
Khan, M.A.2
Kao, S.3
-
36
-
-
0141521594
-
Novel interfering bifunctional molecules against the CCR5 coreceptor are efficient inhibitors of HIV-1 infection
-
Luis AJ, Gonzalez MA, del Real RG, et al. Novel interfering bifunctional molecules against the CCR5 coreceptor are efficient inhibitors of HIV-1 infection. Mol Ther 2003;8:475-84
-
(2003)
Mol Ther
, vol.8
, pp. 475-484
-
-
Luis, A.J.1
Gonzalez, M.A.2
Del Real, R.G.3
-
37
-
-
79551706989
-
Inhibition of early stages of HIV-1 assembly by INI1/hSNF5 transdominant negative mutant S6
-
Cano J, Kalpana GV. Inhibition of early stages of HIV-1 assembly by INI1/hSNF5 transdominant negative mutant S6. J Virol 2011;85:2254-65
-
(2011)
J Virol
, vol.85
, pp. 2254-2265
-
-
Cano, J.1
Kalpana, G.V.2
-
38
-
-
0033066668
-
Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev
-
Reddy TR, Xu W, Mau JK, et al. Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev. Nat Med 1999;5:635-42
-
(1999)
Nat Med
, vol.5
, pp. 635-642
-
-
Reddy, T.R.1
Xu, W.2
Mau, J.K.3
-
39
-
-
56449127254
-
Selective translational repression of HIV-1 RNA by Sam68DeltaC occurs by altering PABP1 binding to unspliced viral RNA
-
Marsh K, Soros V, Cochrane A. Selective translational repression of HIV-1 RNA by Sam68DeltaC occurs by altering PABP1 binding to unspliced viral RNA. Retrovirology 2008;5:97
-
(2008)
Retrovirology
, vol.5
, pp. 97
-
-
Marsh, K.1
Soros, V.2
Cochrane, A.3
-
40
-
-
67650895835
-
Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication
-
Sorin M, Cano J, Das S, et al. Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication. PLoS Pathog 2009;5:e1000463
-
(2009)
PLoS Pathog
, vol.5
, pp. e1000463
-
-
Sorin, M.1
Cano, J.2
Das, S.3
-
41
-
-
0344642957
-
HIV-1 proprotein processing as a target for gene therapy
-
Cordelier P, Zern MA, Strayer DS. HIV-1 proprotein processing as a target for gene therapy. Gene Ther 2003;10:467-77
-
(2003)
Gene Ther
, vol.10
, pp. 467-477
-
-
Cordelier, P.1
Zern, M.A.2
Strayer, D.S.3
-
42
-
-
0037199960
-
Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication
-
Goncalves J, Silva F, Freitas-Vieira A, et al. Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication. J Biol Chem 2002;277:32036-45
-
(2002)
J Biol Chem
, vol.277
, pp. 32036-32045
-
-
Goncalves, J.1
Silva, F.2
Freitas-Vieira, A.3
-
43
-
-
0033080821
-
Inhibition of replication of HIV-1 at both early and late stages of the viral life cycle by single-chain antibody against viral integrase
-
Kitamura Y, Ishikawa T, Okui N, et al. Inhibition of replication of HIV-1 at both early and late stages of the viral life cycle by single-chain antibody against viral integrase. J Acquir Immune Defic Syndr Hum Retrovirol 1999;20:105-14
-
(1999)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.20
, pp. 105-114
-
-
Kitamura, Y.1
Ishikawa, T.2
Okui, N.3
-
44
-
-
10344256143
-
Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase
-
Levy-Mintz P, Duan L, Zhang H, et al. Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase. J Virol 1996;70:8821-32
-
(1996)
J Virol
, vol.70
, pp. 8821-8832
-
-
Levy-Mintz, P.1
Duan, L.2
Zhang, H.3
-
45
-
-
0028914482
-
Inhibition of HIV-1 Tat-mediated LTR transactivation and HIV-1 infection by anti-Tat single chain intrabodies
-
Mhashilkar AM, Bagley J, Chen SY, et al. Inhibition of HIV-1 Tat-mediated LTR transactivation and HIV-1 infection by anti-Tat single chain intrabodies. EMBO J 1995;14:1542-51
-
(1995)
EMBO J
, vol.14
, pp. 1542-1551
-
-
Mhashilkar, A.M.1
Bagley, J.2
Chen, S.Y.3
-
46
-
-
9344264608
-
Targeting human immunodeficiency virus type 1 reverse transcriptase by intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle
-
Shaheen F, Duan L, Zhu M, et al. Targeting human immunodeficiency virus type 1 reverse transcriptase by intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle. J Virol 1996;70:3392-400
-
(1996)
J Virol
, vol.70
, pp. 3392-3400
-
-
Shaheen, F.1
Duan, L.2
Zhu, M.3
-
47
-
-
84866308671
-
In vivo selection of CD4(+) T cells transduced with a gamma-retroviral vector expressing a single-chain intrabody targeting HIV-1 tat
-
Braun SE, Taube R, Zhu Q, et al. In vivo selection of CD4(+) T cells transduced with a gamma-retroviral vector expressing a single-chain intrabody targeting HIV-1 tat. Hum Gene Ther 2012;23:917-31
-
(2012)
Hum Gene Ther
, vol.23
, pp. 917-931
-
-
Braun, S.E.1
Taube, R.2
Zhu, Q.3
-
48
-
-
0035078877
-
Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4
-
BouHamdan M, Strayer DS, Wei D, et al. Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4. Gene Ther 2001;8:408-18
-
(2001)
Gene Ther
, vol.8
, pp. 408-418
-
-
BouHamdan, M.1
Strayer, D.S.2
Wei, D.3
-
49
-
-
84884541189
-
Gene therapy using a secreted single chain variable fragment targeting CCR5 to inhibit HIV infection
-
Falkenhagen A, Ameli M, Asad S, et al. Gene therapy using a secreted single chain variable fragment targeting CCR5 to inhibit HIV infection. J Antivir Antiretrovir 2013;5:85-91
-
(2013)
J Antivir Antiretrovir
, vol.5
, pp. 85-91
-
-
Falkenhagen, A.1
Ameli, M.2
Asad, S.3
-
50
-
-
33745941234
-
T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery
-
Swan CH, Buhler B, Steinberger P, et al. T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery. Gene Ther 2006;13:1480-92
-
(2006)
Gene Ther
, vol.13
, pp. 1480-1492
-
-
Swan, C.H.1
Buhler, B.2
Steinberger, P.3
-
51
-
-
9144270207
-
Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides
-
Egelhofer M, Brandenburg G, Martinius H, et al. Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides. J Virol 2004;78:568-75
-
(2004)
J Virol
, vol.78
, pp. 568-575
-
-
Egelhofer, M.1
Brandenburg, G.2
Martinius, H.3
-
52
-
-
18144380714
-
Suppression of HIV-1 infection in primary CD4 T cells transduced with a self-inactivating lentiviral vector encoding a membrane expressed gp41-derived fusion inhibitor
-
Perez EE, Riley JL, Carroll RG, et al. Suppression of HIV-1 infection in primary CD4 T cells transduced with a self-inactivating lentiviral vector encoding a membrane expressed gp41-derived fusion inhibitor. Clin Immunol 2005;115:26-32
-
(2005)
Clin Immunol
, vol.115
, pp. 26-32
-
-
Perez, E.E.1
Riley, J.L.2
Carroll, R.G.3
-
53
-
-
34247208235
-
Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus
-
van Lunzen J, Glaunsinger T, Stahmer I, et al. Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus. Mol Ther 2007;15:1024-33
-
(2007)
Mol Ther
, vol.15
, pp. 1024-1033
-
-
Van Lunzen, J.1
Glaunsinger, T.2
Stahmer, I.3
-
54
-
-
79959953799
-
Secreted antiviral entry inhibitory (SAVE) peptides for gene therapy of HIV infection
-
Egerer L, Volk A, Kahle J, et al. Secreted antiviral entry inhibitory (SAVE) peptides for gene therapy of HIV infection. Mol Ther 2011;19:1236-44
-
(2011)
Mol Ther
, vol.19
, pp. 1236-1244
-
-
Egerer, L.1
Volk, A.2
Kahle, J.3
-
56
-
-
70350371719
-
Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors
-
Eggink D, Langedijk JP, Bonvin AM, et al. Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors. J Biol Chem 2009;284:26941-50
-
(2009)
J Biol Chem
, vol.284
, pp. 26941-26950
-
-
Eggink, D.1
Langedijk, J.P.2
Bonvin, A.M.3
-
57
-
-
0030940317
-
RANTES inhibits HIV-1 replication in human peripheral blood monocytes and alveolar macrophages
-
Coffey MJ, Woffendin C, Phare SM, et al. RANTES inhibits HIV-1 replication in human peripheral blood monocytes and alveolar macrophages. Am J Physiol 1997;272:L1025-9
-
(1997)
Am J Physiol
, vol.272
, pp. L1025-L1029
-
-
Coffey, M.J.1
Woffendin, C.2
Phare, S.M.3
-
58
-
-
0036290645
-
Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection
-
Schroers R, Davis CM, Wagner HJ, Chen SY. Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection. Gene Ther 2002;9:889-97
-
(2002)
Gene Ther
, vol.9
, pp. 889-897
-
-
Schroers, R.1
Davis, C.M.2
Wagner, H.J.3
Chen, S.Y.4
-
59
-
-
0033659687
-
Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands
-
Simmons G, Reeves JD, Hibbitts S, et al. Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands. Immunol Rev 2000;177:112-26
-
(2000)
Immunol Rev
, vol.177
, pp. 112-126
-
-
Simmons, G.1
Reeves, J.D.2
Hibbitts, S.3
-
60
-
-
0032552429
-
Anti-HIV type 1 activity of wild-type and functional defective RANTES intrakine in primary human lymphocytes
-
Yang AG, Zhang X, Torti F, Chen SY. Anti-HIV type 1 activity of wild-type and functional defective RANTES intrakine in primary human lymphocytes. Hum Gene Ther 1998;9:2005-18
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2005-2018
-
-
Yang, A.G.1
Zhang, X.2
Torti, F.3
Chen, S.Y.4
-
61
-
-
84892615613
-
Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1
-
Chan E, Towers GJ, Qasim W. Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1. Viruses 2014;6:243-63
-
(2014)
Viruses
, vol.6
, pp. 243-263
-
-
Chan, E.1
Towers, G.J.2
Qasim, W.3
-
62
-
-
41149134501
-
Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34 (+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with human fetal tissue
-
Anderson J, Akkina R. Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34 (+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with human fetal tissue. Hum Gene Ther 2008;19:217-28
-
(2008)
Hum Gene Ther
, vol.19
, pp. 217-228
-
-
Anderson, J.1
Akkina, R.2
-
63
-
-
70349655695
-
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
-
Neagu MR, Ziegler P, Pertel T, et al. Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J Clin Invest 2009;119:3035-47
-
(2009)
J Clin Invest
, vol.119
, pp. 3035-3047
-
-
Neagu, M.R.1
Ziegler, P.2
Pertel, T.3
-
64
-
-
84862777555
-
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
-
Lahouassa H, Daddacha W, Hofmann H, et al. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat Immunol 2012;13:223-8
-
(2012)
Nat Immunol
, vol.13
, pp. 223-228
-
-
Lahouassa, H.1
Daddacha, W.2
Hofmann, H.3
-
65
-
-
83555164881
-
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
-
Goldstone DC, Ennis-Adeniran V, Hedden JJ, et al. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature 2011;480:379-82
-
(2011)
Nature
, vol.480
, pp. 379-382
-
-
Goldstone, D.C.1
Ennis-Adeniran, V.2
Hedden, J.J.3
-
66
-
-
84869170593
-
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells
-
Baldauf HM, Pan X, Erikson E, et al. SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. Nat Med 2012;18:1682-7
-
(2012)
Nat Med
, vol.18
, pp. 1682-1687
-
-
Baldauf, H.M.1
Pan, X.2
Erikson, E.3
-
67
-
-
84885761187
-
p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway
-
Allouch A, David A, Amie SM, et al. p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway. Proc Natl Acad Sci USA 2013;110:E3997-4006
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E3997-E4006
-
-
Allouch, A.1
David, A.2
Amie, S.M.3
-
68
-
-
33846809447
-
Primitive hematopoietic cells resist HIV-1 infection via p21
-
Zhang J, Scadden DT, Crumpacker CS. Primitive hematopoietic cells resist HIV-1 infection via p21. J Clin Invest 2007;117:473-81
-
(2007)
J Clin Invest
, vol.117
, pp. 473-481
-
-
Zhang, J.1
Scadden, D.T.2
Crumpacker, C.S.3
-
69
-
-
38049115657
-
The mechanism of human nonhomologous DNA end joining
-
Lieber MR. The mechanism of human nonhomologous DNA end joining. J Biol Chem 2008;283:1-5
-
(2008)
J Biol Chem
, vol.283
, pp. 1-5
-
-
Lieber, M.R.1
-
70
-
-
46949095221
-
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
-
Perez EE, Wang J, Miller JC, et al. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat Biotechnol 2008;26:808-16
-
(2008)
Nat Biotechnol
, vol.26
, pp. 808-816
-
-
Perez, E.E.1
Wang, J.2
Miller, J.C.3
-
71
-
-
79955785236
-
Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases
-
Wilen CB, Wang J, Tilton JC, et al. Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases. PLoS Pathog 2011;7:e1002020
-
(2011)
PLoS Pathog
, vol.7
, pp. e1002020
-
-
Wilen, C.B.1
Wang, J.2
Tilton, J.C.3
-
72
-
-
84862777608
-
Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment
-
Yuan J, Wang J, Crain K, et al. Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment. Mol Ther 2012;20:849-59
-
(2012)
Mol Ther
, vol.20
, pp. 849-859
-
-
Yuan, J.1
Wang, J.2
Crain, K.3
-
73
-
-
84885008722
-
Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells
-
Qu X, Wang P, Ding D, et al. Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells. Nucleic Acids Res 2013;41:7771-82
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 7771-7782
-
-
Qu, X.1
Wang, P.2
Ding, D.3
-
74
-
-
84905409130
-
Zinc-finger endonuclease targeting PSIP-1 inhibits HIV-1 integration
-
Badia R, Pauls E, Riveira-Munoz E, et al. Zinc-finger endonuclease targeting PSIP-1 inhibits HIV-1 integration. Antimicrob Agents Chemother 2014;58(8):4318-27
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.8
, pp. 4318-4327
-
-
Badia, R.1
Pauls, E.2
Riveira-Munoz, E.3
-
75
-
-
84875420616
-
Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5
-
Maier DA, Brennan AL, Jiang S, et al. Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5. Hum Gene Ther 2013;24:245-58
-
(2013)
Hum Gene Ther
, vol.24
, pp. 245-258
-
-
Maier, D.A.1
Brennan, A.L.2
Jiang, S.3
-
77
-
-
77956126894
-
Xanthomonas AvrBs3 family-type III effectors: Discovery and function
-
Boch J, Bonas U. Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu Rev Phytopathol 2010;48:419-36
-
(2010)
Annu Rev Phytopathol
, vol.48
, pp. 419-436
-
-
Boch, J.1
Bonas, U.2
-
78
-
-
84871519181
-
TALENs: A widely applicable technology for targeted genome editing
-
Joung JK, Sander JD. TALENs: a widely applicable technology for targeted genome editing. Nat Rev Mol Cell Biol 2013;14:49-55
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 49-55
-
-
Joung, J.K.1
Sander, J.D.2
-
79
-
-
80053039555
-
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
-
Mussolino C, Morbitzer R, Lutge F, et al. A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Nucleic Acids Res 2011;39:9283-93
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 9283-9293
-
-
Mussolino, C.1
Morbitzer, R.2
Lutge, F.3
-
80
-
-
84876389220
-
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
-
Holkers M, Maggio I, Liu J, et al. Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells. Nucleic Acids Res 2013;41:e63
-
(2013)
Nucleic Acids Res
, vol.41
, pp. e63
-
-
Holkers, M.1
Maggio, I.2
Liu, J.3
-
81
-
-
84907224797
-
TALEN knockout of the PSIP1 gene in human cells: Analyses of HIV-1 replication and allosteric integrase inhibitor mechanism
-
Fadel HJ, Morrison JH, Saenz DT, et al. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. J Virol 2014;88(17):9704-17
-
(2014)
J Virol
, vol.88
, Issue.17
, pp. 9704-9717
-
-
Fadel, H.J.1
Morrison, J.H.2
Saenz, D.T.3
-
83
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM, et al. RNA-guided human genome engineering via Cas9. Science 2013;339:823-6
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
-
84
-
-
84883305437
-
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
-
Ebina H, Misawa N, Kanemura Y, Koyanagi Y. Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus. Sci Rep 2013;3:2510
-
(2013)
Sci Rep
, vol.3
, pp. 2510
-
-
Ebina, H.1
Misawa, N.2
Kanemura, Y.3
Koyanagi, Y.4
-
85
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho SW, Kim S, Kim JM, Kim JS. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat Biotechnol 2013;31:230-2
-
(2013)
Nat Biotechnol
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.S.4
-
86
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 2012;337:816-21
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
-
87
-
-
34347398120
-
HIV-1 proviral DNA excision using an evolved recombinase
-
Sarkar I, Hauber I, Hauber J, Buchholz F. HIV-1 proviral DNA excision using an evolved recombinase. Science 2007;316:1912-15
-
(2007)
Science
, vol.316
, pp. 1912-1915
-
-
Sarkar, I.1
Hauber, I.2
Hauber, J.3
Buchholz, F.4
-
88
-
-
84884680571
-
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice
-
Hauber I, Hofmann-Sieber H, Chemnitz J, et al. Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice. PLoS Pathog 2013;9:e1003587
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003587
-
-
Hauber, I.1
Hofmann-Sieber, H.2
Chemnitz, J.3
-
90
-
-
33846676217
-
Use of modified U1 snRNAs to inhibit HIV-1 replication
-
Sajic R, Lee K, Asai K, et al. Use of modified U1 snRNAs to inhibit HIV-1 replication. Nucleic Acids Res 2007;35:247-55
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 247-255
-
-
Sajic, R.1
Lee, K.2
Asai, K.3
-
91
-
-
84860298138
-
Design of modified U1i molecules against HIV-1 RNA
-
Knoepfel SA, Abad A, Abad X, et al. Design of modified U1i molecules against HIV-1 RNA. Antiviral Res 2012;94:208-16
-
(2012)
Antiviral Res
, vol.94
, pp. 208-216
-
-
Knoepfel, S.A.1
Abad, A.2
Abad, X.3
-
93
-
-
0025837282
-
Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation
-
Sullenger BA, Gallardo HF, Ungers GE, Gilboa E. Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. J Virol 1991;65:6811-16
-
(1991)
J Virol
, vol.65
, pp. 6811-6816
-
-
Sullenger, B.A.1
Gallardo, H.F.2
Ungers, G.E.3
Gilboa, E.4
-
94
-
-
0025188193
-
Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication
-
Sullenger BA, Gallardo HF, Ungers GE, Gilboa E. Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication. Cell 1990;63:601-8
-
(1990)
Cell
, vol.63
, pp. 601-608
-
-
Sullenger, B.A.1
Gallardo, H.F.2
Ungers, G.E.3
Gilboa, E.4
-
95
-
-
0026521479
-
Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells
-
Lee TC, Sullenger BA, Gallardo HF, et al. Overexpression of RRE-derived sequences inhibits HIV-1 replication in CEM cells. New Biol 1992;4:66-74
-
(1992)
New Biol
, vol.4
, pp. 66-74
-
-
Lee, T.C.1
Sullenger, B.A.2
Gallardo, H.F.3
-
97
-
-
0036940586
-
RNA-based anti-HIV-1 gene therapeutic constructs in SCID-hu mouse model
-
Bai J, Banda N, Lee NS, et al. RNA-based anti-HIV-1 gene therapeutic constructs in SCID-hu mouse model. Mol Ther 2002;6:770-82
-
(2002)
Mol Ther
, vol.6
, pp. 770-782
-
-
Bai, J.1
Banda, N.2
Lee, N.S.3
-
98
-
-
23644454894
-
Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages
-
Banerjea A, Li MJ, Remling L, et al. Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages. AIDS Res Ther 2004;1:2
-
(2004)
AIDS Res Ther
, vol.1
, pp. 2
-
-
Banerjea, A.1
Li, M.J.2
Remling, L.3
-
99
-
-
0033168686
-
A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children
-
Kohn DB, Bauer G, Rice CR, et al. A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children. Blood 1999;94:368-71
-
(1999)
Blood
, vol.94
, pp. 368-371
-
-
Kohn, D.B.1
Bauer, G.2
Rice, C.R.3
-
100
-
-
3042818032
-
Efficacy and mode of action of hammerhead and hairpin ribozymes against various HIV-1 target sites
-
Hotchkiss G, Maijgren-Steffensson C, Ahrlund-Richter L. Efficacy and mode of action of hammerhead and hairpin ribozymes against various HIV-1 target sites. Mol Ther 2004;10:172-80
-
(2004)
Mol Ther
, vol.10
, pp. 172-180
-
-
Hotchkiss, G.1
Maijgren-Steffensson, C.2
Ahrlund-Richter, L.3
-
101
-
-
0030051703
-
A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1
-
Yamada O, Kraus G, Luznik L, et al. A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1. J Virol 1996;70:1596-601
-
(1996)
J Virol
, vol.70
, pp. 1596-1601
-
-
Yamada, O.1
Kraus, G.2
Luznik, L.3
-
102
-
-
12144291445
-
Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: Myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients
-
Amado RG, Mitsuyasu RT, Rosenblatt JD, et al. Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients. Hum Gene Ther 2004;15:251-62
-
(2004)
Hum Gene Ther
, vol.15
, pp. 251-262
-
-
Amado, R.G.1
Mitsuyasu, R.T.2
Rosenblatt, J.D.3
-
103
-
-
21144470101
-
Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients
-
MacPherson JL, Boyd MP, Arndt AJ, et al. Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients. J Gene Med 2005;7:552-64
-
(2005)
J Gene Med
, vol.7
, pp. 552-564
-
-
MacPherson, J.L.1
Boyd, M.P.2
Arndt, A.J.3
-
104
-
-
1342290190
-
RNA-mediated inhibition of HIV in a gene therapy setting
-
Michienzi A, Castanotto D, Lee N, et al. RNA-mediated inhibition of HIV in a gene therapy setting. Ann N Y Acad Sci 2003;1002:63-71
-
(2003)
Ann N Y Acad Sci
, vol.1002
, pp. 63-71
-
-
Michienzi, A.1
Castanotto, D.2
Lee, N.3
-
106
-
-
77955608799
-
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma
-
DiGiusto DL, Krishnan A, Li L, et al. RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Sci Transl Med 2010;2:36-43
-
(2010)
Sci Transl Med
, vol.2
, pp. 36-43
-
-
DiGiusto, D.L.1
Krishnan, A.2
Li, L.3
-
107
-
-
0029864546
-
Intracellular expression of RNA transcripts complementary to the human immunodeficiency virus type 1 gag gene inhibits viral replication in human CD4+ lymphocytes
-
Veres G, Escaich S, Baker J, et al. Intracellular expression of RNA transcripts complementary to the human immunodeficiency virus type 1 gag gene inhibits viral replication in human CD4+ lymphocytes. J Virol 1996;70:8792-800
-
(1996)
J Virol
, vol.70
, pp. 8792-8800
-
-
Veres, G.1
Escaich, S.2
Baker, J.3
-
108
-
-
2942639506
-
Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance
-
Lu X, Yu Q, Binder GK, et al. Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance. J Virol 2004;78:7079-88
-
(2004)
J Virol
, vol.78
, pp. 7079-7088
-
-
Lu, X.1
Yu, Q.2
Binder, G.K.3
-
109
-
-
3042735441
-
Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load
-
Humeau LM, Binder GK, Lu X, et al. Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load. Mol Ther 2004;9:902-13
-
(2004)
Mol Ther
, vol.9
, pp. 902-913
-
-
Humeau, L.M.1
Binder, G.K.2
Lu, X.3
-
110
-
-
0025834035
-
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element
-
Vickers T, Baker BF, Cook PD, et al. Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element. Nucleic Acids Res 1991;19:3359-68
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3359-3368
-
-
Vickers, T.1
Baker, B.F.2
Cook, P.D.3
-
111
-
-
0026528771
-
Structural features in TAR RNA of human and simian immunodeficiency viruses: A phylogenetic analysis
-
Berkhout B. Structural features in TAR RNA of human and simian immunodeficiency viruses: a phylogenetic analysis. Nucleic Acids Res 1992;20:27-31
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 27-31
-
-
Berkhout, B.1
-
112
-
-
84896475853
-
Phylogenetic study on structural elements of HIV-1 poly(A) region. 2. USE domain and TAR hairpin
-
Zarudnaya MI, Potyahaylo AL, Kolomiets IM, Hovorun DM. Phylogenetic study on structural elements of HIV-1 poly(A) region. 2. USE domain and TAR hairpin. Biopolymers Cell 2014;30:29-36
-
(2014)
Biopolymers Cell
, vol.30
, pp. 29-36
-
-
Zarudnaya, M.I.1
Potyahaylo, A.L.2
Kolomiets, I.M.3
Hovorun, D.M.4
-
113
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
Levine BL, Humeau LM, Boyer J, et al. Gene transfer in humans using a conditionally replicating lentiviral vector. Proc Natl Acad Sci USA 2006;103:17372-7
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
-
114
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411:494-8
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
115
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
116
-
-
1642564331
-
Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance
-
Anderson J, Banerjea A, Akkina R. Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance. Oligonucleotides 2003;13:303-12
-
(2003)
Oligonucleotides
, vol.13
, pp. 303-312
-
-
Anderson, J.1
Banerjea, A.2
Akkina, R.3
-
117
-
-
22744451729
-
Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1
-
Chang LJ, Liu X, He J. Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1. Gene Ther 2005;12:1133-44
-
(2005)
Gene Ther
, vol.12
, pp. 1133-1144
-
-
Chang, L.J.1
Liu, X.2
He, J.3
-
118
-
-
78650904206
-
Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors
-
Eekels JJ, Geerts D, Jeeninga RE, Berkhout B. Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors. Antiviral Res 2011;89:43-53
-
(2011)
Antiviral Res
, vol.89
, pp. 43-53
-
-
Eekels, J.J.1
Geerts, D.2
Jeeninga, R.E.3
Berkhout, B.4
-
119
-
-
0036891843
-
RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication
-
Surabhi RM, Gaynor RB. RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication. J Virol 2002;76:12963-73
-
(2002)
J Virol
, vol.76
, pp. 12963-12973
-
-
Surabhi, R.M.1
Gaynor, R.B.2
-
120
-
-
65949091600
-
Stringent testing identifies highly potent and escape-proof anti-HIV short hairpin RNAs
-
von Eije KJ, Ter Brake O, Berkhout B. Stringent testing identifies highly potent and escape-proof anti-HIV short hairpin RNAs. J Gene Med 2009;11:459-67
-
(2009)
J Gene Med
, vol.11
, pp. 459-467
-
-
Von Eije, K.J.1
Ter Brake, O.2
Berkhout, B.3
-
121
-
-
33745384405
-
A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication
-
Westerhout EM, Vink M, Haasnoot PC, et al. A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication. Mol Ther 2006;14:268-75
-
(2006)
Mol Ther
, vol.14
, pp. 268-275
-
-
Westerhout, E.M.1
Vink, M.2
Haasnoot, P.C.3
-
122
-
-
34548574859
-
Lentiviral vectors that carry anti-HIV shRNAs: Problems and solutions
-
Ter Brake O, Berkhout B. Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions. J Gene Med 2007;9:743-50
-
(2007)
J Gene Med
, vol.9
, pp. 743-750
-
-
Ter Brake, O.1
Berkhout, B.2
-
123
-
-
84879873039
-
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy
-
Biffi A, Montini E, Lorioli L, et al. Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science 2013;341:1233158
-
(2013)
Science
, vol.341
, pp. 1233158
-
-
Biffi, A.1
Montini, E.2
Lorioli, L.3
-
124
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D, Streetz KL, Jopling CL, et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006;441:537-41
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
-
125
-
-
84906851063
-
Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity
-
Herrera-Carrillo E, Harwig A, Liu YP, Berkhout B. Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity. RNA 2014;20:1410-18
-
(2014)
RNA
, vol.20
, pp. 1410-1418
-
-
Herrera-Carrillo, E.1
Harwig, A.2
Liu, Y.P.3
Berkhout, B.4
-
127
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge AJ, Pebernard S, Ducraux A, et al. Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet 2003;34:263-4
-
(2003)
Nat Genet
, vol.34
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
-
128
-
-
84900321291
-
Towards improved shRNA and miRNA reagents as inhibitors of HIV-1 replication
-
Berkhout B, Liu YP. Towards improved shRNA and miRNA reagents as inhibitors of HIV-1 replication. Future Microbiol 2014;9:561-71
-
(2014)
Future Microbiol
, vol.9
, pp. 561-571
-
-
Berkhout, B.1
Liu, Y.P.2
-
129
-
-
77953124494
-
Anticipating and blocking HIV-1 escape by second generation antiviral shRNAs
-
Schopman NC, Ter Brake O, Berkhout B. Anticipating and blocking HIV-1 escape by second generation antiviral shRNAs. Retrovirology 2010;7:52
-
(2010)
Retrovirology
, vol.7
, pp. 52
-
-
Schopman, N.C.1
Ter Brake, O.2
Berkhout, B.3
-
130
-
-
33751001588
-
Silencing of HIV-1 with RNA interference: A multiple shRNA approach
-
Ter Brake O, Konstantinova P, Ceylan M, Berkhout B. Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol Ther 2006;14:883-92
-
(2006)
Mol Ther
, vol.14
, pp. 883-892
-
-
Ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
131
-
-
39849108343
-
Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition
-
ter Brake O, 't Hooft K, Liu YP, et al. Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition. Mol Ther 2008;16:557-64
-
(2008)
Mol Ther
, vol.16
, pp. 557-564
-
-
Ter Brake, O.1
'T Hooft, K.2
Liu, Y.P.3
-
132
-
-
44349164025
-
Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
-
Liu YP, Haasnoot J, Ter Brake O, et al. Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res 2008;36:2811-24
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2811-2824
-
-
Liu, Y.P.1
Haasnoot, J.2
Ter Brake, O.3
-
133
-
-
71049186345
-
RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs
-
Snyder LL, Ahmed I, Steel LF. RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs. Nucleic Acids Res 2009;37:e127
-
(2009)
Nucleic Acids Res
, vol.37
, pp. e127
-
-
Snyder, L.L.1
Ahmed, I.2
Steel, L.F.3
-
134
-
-
70349887777
-
Combinatorial RNAi against HIV-1 using extended short hairpin RNAs
-
Liu YP, von Eije KJ, Schopman NC, et al. Combinatorial RNAi against HIV-1 using extended short hairpin RNAs. Mol Ther 2009;17:1712-23
-
(2009)
Mol Ther
, vol.17
, pp. 1712-1723
-
-
Liu, Y.P.1
Von Eije, K.J.2
Schopman, N.C.3
-
135
-
-
34848814237
-
Design of extended short hairpin RNAs for HIV-1 inhibition
-
Liu YP, Haasnoot J, Berkhout B. Design of extended short hairpin RNAs for HIV-1 inhibition. Nucleic Acids Res 2007;35:5683-93
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5683-5693
-
-
Liu, Y.P.1
Haasnoot, J.2
Berkhout, B.3
-
136
-
-
33748850724
-
Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA
-
Konstantinova P, de Vries W, Haasnoot J, et al. Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA. Gene Ther 2006;13:1403-13
-
(2006)
Gene Ther
, vol.13
, pp. 1403-1413
-
-
Konstantinova, P.1
De Vries, W.2
Haasnoot, J.3
-
137
-
-
77957807722
-
Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors
-
Saayman S, Arbuthnot P, Weinberg MS. Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors. Nucleic Acids Res 2010;38:6652-63
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6652-6663
-
-
Saayman, S.1
Arbuthnot, P.2
Weinberg, M.S.3
-
138
-
-
67149100493
-
Combinatorial RNAi strategies against HIV-1 and other escape-prone viruses
-
Liu YP, Berkhout B. Combinatorial RNAi strategies against HIV-1 and other escape-prone viruses. Int J BioSci Technol 2008;1:1-10
-
(2008)
Int J BioSci Technol
, vol.1
, pp. 1-10
-
-
Liu, Y.P.1
Berkhout, B.2
-
139
-
-
84875311939
-
Antiviral strategies combining antiretroviral drugs with RNAi-mediated attack on HIV-1 and cellular co-factors
-
Boutimah F, Eekels JJ, Liu YP, Berkhout B. Antiviral strategies combining antiretroviral drugs with RNAi-mediated attack on HIV-1 and cellular co-factors. Antiviral Res 2013;98:121-9
-
(2013)
Antiviral Res
, vol.98
, pp. 121-129
-
-
Boutimah, F.1
Eekels, J.J.2
Liu, Y.P.3
Berkhout, B.4
-
140
-
-
84455169971
-
Directed HIV-1 evolution of protease inhibitor resistance by second-generation short hairpin RNAs
-
Schopman NC, Braun A, Berkhout B. Directed HIV-1 evolution of protease inhibitor resistance by second-generation short hairpin RNAs. Antimicrob Agents Chemother 2012;56:479-86
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 479-486
-
-
Schopman, N.C.1
Braun, A.2
Berkhout, B.3
-
141
-
-
77955608799
-
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma
-
DiGiusto DL, Krishnan A, Li L, et al. RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Sci Transl Med 2010;2:36ra43
-
(2010)
Sci Transl Med
, vol.2
, pp. 36ra43
-
-
DiGiusto, D.L.1
Krishnan, A.2
Li, L.3
-
142
-
-
13844320402
-
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
-
Westerhout EM, Ooms M, Vink M, et al. HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res 2005;33:796-804
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 796-804
-
-
Westerhout, E.M.1
Ooms, M.2
Vink, M.3
-
143
-
-
34547843654
-
A systematic analysis of the effect of target RNA structure on RNA interference
-
Westerhout EM, Berkhout B. A systematic analysis of the effect of target RNA structure on RNA interference. Nucleic Acids Res 2007;35:4322-30
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4322-4330
-
-
Westerhout, E.M.1
Berkhout, B.2
-
144
-
-
84859441439
-
SHAPE-directed discovery of potent shRNA inhibitors of HIV-1
-
Low JT, Knoepfel SA, Watts JM, et al. SHAPE-directed discovery of potent shRNA inhibitors of HIV-1. Mol Ther 2012;20:820-8
-
(2012)
Mol Ther
, vol.20
, pp. 820-828
-
-
Low, J.T.1
Knoepfel, S.A.2
Watts, J.M.3
-
145
-
-
84890379963
-
Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1
-
Centlivre M, Legrand N, Klamer S, et al. Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1. Mol Ther Nucleic Acids 2013;2:e120
-
(2013)
Mol Ther Nucleic Acids
, vol.2
, pp. e120
-
-
Centlivre, M.1
Legrand, N.2
Klamer, S.3
-
146
-
-
84895501470
-
The impact of unprotected T cells in RNAi-based gene therapy for HIV-AIDS
-
Herrera-Carrillo E, Liu YP, Berkhout B. The impact of unprotected T cells in RNAi-based gene therapy for HIV-AIDS. Mol Ther 2014;22:596-606
-
(2014)
Mol Ther
, vol.22
, pp. 596-606
-
-
Herrera-Carrillo, E.1
Liu, Y.P.2
Berkhout, B.3
-
147
-
-
77953642976
-
Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies
-
Liu YP, Vink MA, Westerink JT, et al. Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies. RNA 2010;16:1328-39
-
(2010)
RNA
, vol.16
, pp. 1328-1339
-
-
Liu, Y.P.1
Vink, M.A.2
Westerink, J.T.3
-
148
-
-
84879873039
-
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy
-
Biffi A, Montini E, Lorioli L, et al. Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science 2013;341:864
-
(2013)
Science
, vol.341
, pp. 864
-
-
Biffi, A.1
Montini, E.2
Lorioli, L.3
-
149
-
-
84879867061
-
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome
-
Aiuti A, Biasco L, Scaramuzza S, et al. Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome. Science 2013;341:865
-
(2013)
Science
, vol.341
, pp. 865
-
-
Aiuti, A.1
Biasco, L.2
Scaramuzza, S.3
-
150
-
-
70449427834
-
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
-
Cartier N, Hacein-Bey-Abina S, Bartholomae CC, et al. Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 2009;326:818-23
-
(2009)
Science
, vol.326
, pp. 818-823
-
-
Cartier, N.1
Hacein-Bey-Abina, S.2
Bartholomae, C.C.3
-
151
-
-
84876475656
-
Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV
-
Tebas P, Stein D, Binder-Scholl G, et al. Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV. Blood 2013;121:1524-33
-
(2013)
Blood
, vol.121
, pp. 1524-1533
-
-
Tebas, P.1
Stein, D.2
Binder-Scholl, G.3
-
152
-
-
0033650534
-
Autologous hematopoietic cell transplantation in Hodgkin's disease
-
Johnston LJ, Horning SJ. Autologous hematopoietic cell transplantation in Hodgkin's disease. Biol Blood Marrow Transplant 2000;6:289-300
-
(2000)
Biol Blood Marrow Transplant
, vol.6
, pp. 289-300
-
-
Johnston, L.J.1
Horning, S.J.2
-
153
-
-
78651304712
-
Management of relapsed and refractory classical Hodgkin lymphoma in children and adolescents
-
Daw S, Wynn R, Wallace H. Management of relapsed and refractory classical Hodgkin lymphoma in children and adolescents. Br J Haematol 2011;152:249-60
-
(2011)
Br J Haematol
, vol.152
, pp. 249-260
-
-
Daw, S.1
Wynn, R.2
Wallace, H.3
-
154
-
-
0344197155
-
Autologous hematopoietic stem-cell transplantation for relapsed or refractory Hodgkin's disease in children and adolescents
-
Baker KS, Gordon BG, Gross TG, et al. Autologous hematopoietic stem-cell transplantation for relapsed or refractory Hodgkin's disease in children and adolescents. J Clin Oncol 1999;17:825-31
-
(1999)
J Clin Oncol
, vol.17
, pp. 825-831
-
-
Baker, K.S.1
Gordon, B.G.2
Gross, T.G.3
-
155
-
-
84907283632
-
A myeloablative conditioning regimen with fludarabine demonstrates good results in UCBT for 30 pediatric patients with hematologic malignancies, especially acute lymphoblastic leukemia
-
Tong J, Sun Z, Liu H, et al. A myeloablative conditioning regimen with fludarabine demonstrates good results in UCBT for 30 pediatric patients with hematologic malignancies, especially acute lymphoblastic leukemia. Neoplasma 2014;61:593-600
-
(2014)
Neoplasma
, vol.61
, pp. 593-600
-
-
Tong, J.1
Sun, Z.2
Liu, H.3
-
156
-
-
84864345953
-
Towards an HIV cure: A global scientific strategy
-
Deeks SG, Autran B, Berkhout B, et al. Towards an HIV cure: a global scientific strategy. Nat Rev Immunol 2012;12:607-14
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 607-614
-
-
Deeks, S.G.1
Autran, B.2
Berkhout, B.3
-
157
-
-
84892652602
-
The many lives of CTIP2: From AIDS to cancer and cardiac hypertrophy
-
Le Douce V, Cherrier T, Riclet R, et al. The many lives of CTIP2: from AIDS to cancer and cardiac hypertrophy. J Cell Physiol 2014;229:533-7
-
(2014)
J Cell Physiol
, vol.229
, pp. 533-537
-
-
Le Douce, V.1
Cherrier, T.2
Riclet, R.3
-
158
-
-
84858436446
-
LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing
-
Le Douce V, Colin L, Redel L, et al. LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing. Nucleic Acids Res 2012;40:1904-15
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1904-1915
-
-
Le Douce, V.1
Colin, L.2
Redel, L.3
-
159
-
-
84859612103
-
Achieving a cure for HIV infection: Do we have reasons to be optimistic?
-
Le Douce V, Janossy A, Hallay H, et al. Achieving a cure for HIV infection: do we have reasons to be optimistic? J Antimicrob Chemother 2012;67:1063-74
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 1063-1074
-
-
Le Douce, V.1
Janossy, A.2
Hallay, H.3
-
160
-
-
33846536395
-
Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing
-
Marban C, Suzanne S, Dequiedt F, et al. Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing. EMBO J 2007;26:412-23
-
(2007)
EMBO J
, vol.26
, pp. 412-423
-
-
Marban, C.1
Suzanne, S.2
Dequiedt, F.3
-
161
-
-
49049107011
-
Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA
-
Pasternak AO, Adema KW, Bakker M, et al. Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA. J Clin Microbiol 2008;46:2206-11
-
(2008)
J Clin Microbiol
, vol.46
, pp. 2206-2211
-
-
Pasternak, A.O.1
Adema, K.W.2
Bakker, M.3
-
162
-
-
84876111496
-
Cell-associated HIV RNA: A dynamic biomarker of viral persistence
-
Pasternak AO, Lukashov VV, Berkhout B. Cell-associated HIV RNA: a dynamic biomarker of viral persistence. Retrovirology 2013;10:41
-
(2013)
Retrovirology
, vol.10
, pp. 41
-
-
Pasternak, A.O.1
Lukashov, V.V.2
Berkhout, B.3
-
163
-
-
84875985311
-
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
-
Saez-Cirion A, Bacchus C, Hocqueloux L, et al. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 2013;9:e1003211
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003211
-
-
Saez-Cirion, A.1
Bacchus, C.2
Hocqueloux, L.3
-
164
-
-
84907518965
-
HIV epidemiology. The early spread and epidemic ignition of HIV-1 in human populations
-
Faria NR, Rambaut A, Suchard MA, et al. HIV epidemiology. The early spread and epidemic ignition of HIV-1 in human populations. Science 2014;346:56-61
-
(2014)
Science
, vol.346
, pp. 56-61
-
-
Faria, N.R.1
Rambaut, A.2
Suchard, M.A.3
-
165
-
-
39849108343
-
Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition
-
Ter Brake O, Hooft K, Liu YP, et al. Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition. Mol Ther 2008;16:557-64
-
(2008)
Mol Ther
, vol.16
, pp. 557-564
-
-
Ter Brake, O.1
Hooft, K.2
Liu, Y.P.3
-
166
-
-
0025794308
-
Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4
-
Daar ES, Ho DD. Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4. Am J Med 1991;90:22S-6S
-
(1991)
Am J Med
, vol.90
, pp. 22S-6S
-
-
Daar, E.S.1
Ho, D.D.2
-
167
-
-
0027985209
-
Further evaluation of soluble CD4 as an anti-HIV type 1 gene therapy: Demonstration of protection of primary human peripheral blood lymphocytes from infection by HIV type 1
-
Morgan RA, Baler-Bitterlich G, Ragheb JA, et al. Further evaluation of soluble CD4 as an anti-HIV type 1 gene therapy: demonstration of protection of primary human peripheral blood lymphocytes from infection by HIV type 1. AIDS Res Hum Retroviruses 1994;10:1507-15
-
(1994)
AIDS Res Hum Retroviruses
, vol.10
, pp. 1507-1515
-
-
Morgan, R.A.1
Baler-Bitterlich, G.2
Ragheb, J.A.3
-
168
-
-
9944222768
-
Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4
-
Zhou N, Fang J, Mukhtar M, et al. Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene Ther 2004;11:1703-12
-
(2004)
Gene Ther
, vol.11
, pp. 1703-1712
-
-
Zhou, N.1
Fang, J.2
Mukhtar, M.3
-
169
-
-
0025324686
-
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat
-
Pearson L, Garcia J, Wu F, et al. A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat. Proc Natl Acad Sci USA 1990;87:5079-83
-
(1990)
Proc Natl Acad Sci USA
, Issue.87
, pp. 5079-5083
-
-
Pearson, L.1
Garcia, J.2
Wu, F.3
-
170
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J Virol 2002;76:9225-31
-
(2002)
J Virol
, vol.76
, pp. 9225-9231
-
-
Coburn, G.A.1
Cullen, B.R.2
-
171
-
-
0036839458
-
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference
-
Capodici J, Kariko K, Weissman D. Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. J Immunol 2002;169:5196-201
-
(2002)
J Immunol
, vol.169
, pp. 5196-5201
-
-
Capodici, J.1
Kariko, K.2
Weissman, D.3
-
172
-
-
0036802425
-
Gene therapy-based treatment for HIV-positive patients with malignancies
-
Kang EM, De WM, Malech H, et al. Gene therapy-based treatment for HIV-positive patients with malignancies. J Hematother Stem Cell Res 2002;11:809-16
-
(2002)
J Hematother Stem Cell Res
, vol.11
, pp. 809-816
-
-
Kang, E.M.1
De, W.M.2
Malech, H.3
-
173
-
-
84863457438
-
T-lymphocyte perturbation following large-scale apheresis and hematopoietic stem cell transplantation in HIV-infected individuals
-
Savkovic B, MacPherson JL, Zaunders J, et al. T-lymphocyte perturbation following large-scale apheresis and hematopoietic stem cell transplantation in HIV-infected individuals. Clin Immunol 2012;144:159-71
-
(2012)
Clin Immunol
, vol.144
, pp. 159-171
-
-
Savkovic, B.1
MacPherson, J.L.2
Zaunders, J.3
-
174
-
-
84921316616
-
-
Available from
-
Available from: http://clinicaltrials.gov/[Accessed 15th July 2014]
-
Accessed 15th July 2014
-
-
|