-
1
-
-
33744520104
-
Molecular basis for the recognition of primary micrornas by the Drosha-Dgcr8 complex
-
Han J, Lee Y, Yeom KH et al. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125(5), 887-901 (2006).
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
-
2
-
-
84874086395
-
Beyond secondary structure: Primary-sequence determinants license Pri-Mirna hairpins for processing
-
Auyeung VC, Ulitsky I, McGeary SE, Bartel DP. Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. Cell 152(4), 844-858 (2013).
-
(2013)
Cell
, vol.152
, Issue.4
, pp. 844-858
-
-
Auyeung, V.C.1
Ulitsky, I.2
McGeary, S.E.3
Bartel, D.P.4
-
3
-
-
23644433363
-
TRBP recruits the dicer complex to Ago2 for microrna processing and gene silencing
-
Chendrimada TP, Gregory RI, Kumaraswamy E et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436(7051), 740-744 (2005).
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
-
4
-
-
0346094457
-
Prediction of mammalian microrna targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 115(7), 787-798 (2003).
-
(2003)
Cell
, vol.115
, Issue.7
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
5
-
-
0032529846
-
Prostaglandin e2 induces the final maturation of il-12-deficient CD1A-CD83- dendritic cells: The levels of il-12 are determined during the final dendritic cell maturation and are resistant to further modulation
-
Kalinski P, Schuitemaker JH, Hilkens CM, Kapsenberg ML. Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a-CD83-dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation. J. Immunol. 161(6), 2804-2809 (1998).
-
(1998)
J. Immunol
, vol.161
, Issue.6
, pp. 2804-2809
-
-
Kalinski, P.1
Schuitemaker, J.H.2
Hilkens, C.M.3
Kapsenberg, M.L.4
-
6
-
-
2142654329
-
Microrna-directed cleavage of hoxb8 mrna
-
Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304(5670), 594-596 (2004).
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
7
-
-
84885635441
-
RNA interference functions as an antiviral immunity mechanism in mammals
-
Li Y, Lu J, Han Y, Fan X, Ding SW. RNA interference functions as an antiviral immunity mechanism in mammals. Science 342(6155), 231-234 (2013).
-
(2013)
Science
, vol.342
, Issue.6155
, pp. 231-234
-
-
Li, Y.1
Lu, J.2
Han, Y.3
Fan, X.4
Ding, S.W.5
-
8
-
-
84885583303
-
Antiviral rna interference in mammalian cells
-
Maillard PV, Ciaudo C, Marchais A et al. Antiviral RNA interference in mammalian cells. Science 342(6155), 235-238 (2013).
-
(2013)
Science
, vol.342
, Issue.6155
, pp. 235-238
-
-
Maillard, P.V.1
Ciaudo, C.2
Marchais, A.3
-
9
-
-
34447107760
-
The mirtron pathway generates microrna-Class regulatory rnas in drosophila
-
Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130(1), 89-100 (2007).
-
(2007)
Cell
, vol.130
, Issue.1
, pp. 89-100
-
-
Okamura, K.1
Hagen, J.W.2
Duan, H.3
Tyler, D.M.4
Lai, E.C.5
-
10
-
-
34447097693
-
Intronic microrna precursors that bypass drosha processing
-
Ruby JG, Jan CH, Bartel DP. Intronic microRNA precursors that bypass Drosha processing. Nature 448(7149), 83-86 (2007).
-
(2007)
Nature
, vol.448
, Issue.7149
, pp. 83-86
-
-
Ruby, J.G.1
Jan, C.H.2
Bartel, D.P.3
-
11
-
-
84859963228
-
Biogenesis of mammalian micrornas by a non-Canonical processing pathway
-
Havens MA, Reich AA, Duelli DM, Hastings ML. Biogenesis of mammalian microRNAs by a non-canonical processing pathway. Nucleic Acids Res. 40(10), 4626-4640 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.10
, pp. 4626-4640
-
-
Havens, M.A.1
Reich, A.A.2
Duelli, D.M.3
Hastings, M.L.4
-
12
-
-
73649109602
-
A mammalian herpes virus uses noncanonical expression and processing mechanisms to generate viral micrornas
-
Bogerd HP, Karnowski HW, Cai X, Shin J, Pohlers M, Cullen BR. A mammalian herpes virus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs. Mol. Cell 37(1), 135-142 (2010).
-
(2010)
Mol. Cell
, vol.37
, Issue.1
, pp. 135-142
-
-
Bogerd, H.P.1
Karnowski, H.W.2
Cai, X.3
Shin, J.4
Pohlers, M.5
Cullen, B.R.6
-
13
-
-
2342420041
-
Identification of virus-Encoded micrornas
-
Pfeffer S, Zavolan M, Grasser FA et al. Identification of virus-encoded microRNAs. Science 304(5671), 734-736 (2004).
-
(2004)
Science
, vol.304
, Issue.5671
, pp. 734-736
-
-
Pfeffer, S.1
Zavolan, M.2
Grasser, F.A.3
-
14
-
-
77955290050
-
Many ways to generate microrna-like small rnas: Non-canonical pathways for microrna production
-
Miyoshi K, Miyoshi T, Siomi H. Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production. Mol. Genet. Genomics 284(2), 95-103 (2010).
-
(2010)
Mol. Genet. Genomics
, vol.284
, Issue.2
, pp. 95-103
-
-
Miyoshi, K.1
Miyoshi, T.2
Siomi, H.3
-
15
-
-
80052996141
-
Alternative mirna biogenesis pathways and the interpretation of core mirna pathway mutants
-
Yang JS, Lai EC. Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Mol. Cell 43(6), 892-903 (2011).
-
(2011)
Mol. Cell
, vol.43
, Issue.6
, pp. 892-903
-
-
Yang, J.S.1
Lai, E.C.2
-
16
-
-
71549169628
-
Filtering of deep sequencing data reveals the existence of abundant dicer-dependent small rnas derived from trnas
-
Cole C, Sobala A, Lu C et al. Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs. RNA. 15(12), 2147-2160 (2009).
-
(2009)
RNA
, vol.15
, Issue.12
, pp. 2147-2160
-
-
Cole, C.1
Sobala, A.2
Lu, C.3
-
19
-
-
70349652191
-
The non-coding rna of the multidrug resistance-linked vault particle encodes multiple regulatory small rnas
-
Persson H, Kvist A, Vallon-Christersson J, Medstrand P, Borg A, Rovira C. The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs. Nat. Cell Biol. 11(10), 1268-1271 (2009).
-
(2009)
Nat. Cell Biol
, vol.11
, Issue.10
, pp. 1268-1271
-
-
Persson, H.1
Kvist, A.2
Vallon-Christersson, J.3
Medstrand, P.4
Borg, A.5
Rovira, C.6
-
20
-
-
84855293838
-
Mirdeep2 accurately identifies known and hundreds of novel microrna genes in seven animal clades
-
Friedlander MR, Mackowiak SD, Li N, Chen W, Rajewsky N. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res. 40(1), 37-52 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.1
, pp. 37-52
-
-
Friedlander, M.R.1
Mackowiak, S.D.2
Li, N.3
Chen, W.4
Rajewsky, N.5
-
21
-
-
84871822658
-
Dicer-processed small rnas: Rules and exceptions
-
Langenberger D, Cakir MV, Hoffmann S, Stadler PF. Dicer-processed small RNAs: rules and exceptions. J. Exp. Zool. B Mol. Dev. Evol. 320(1), 35-46 (2013).
-
(2013)
J. Exp. Zool. B Mol. Dev. Evol
, vol.320
, Issue.1
, pp. 35-46
-
-
Langenberger, D.1
Cakir, M.V.2
Hoffmann, S.3
Stadler, P.F.4
-
22
-
-
36849048778
-
Dual role for argonautes in microrna processing and posttranscriptional regulation of microrna expression
-
Diederichs S, Haber DA. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 131(6), 1097-1108 (2007).
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1097-1108
-
-
Diederichs, S.1
Haber, D.A.2
-
23
-
-
18344369543
-
Microrna biogenesis: Coordinated cropping and dicing
-
Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 6(5), 376-385 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, Issue.5
, pp. 376-385
-
-
Kim, V.N.1
-
24
-
-
77953183812
-
A dicer-Independent mirna biogenesis pathway that requires ago catalysis
-
Cheloufi S, Dos Santos CO, Chong MM, Hannon GJ. A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 465(7298), 584-589 (2010).
-
(2010)
Nature
, vol.465
, Issue.7298
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.O.2
Chong, M.M.3
Hannon, G.J.4
-
25
-
-
13844280638
-
Synthetic shrnas as potent rnai triggers
-
Siolas D, Lerner C, Burchard J et al. Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 23(2), 227-231 (2005).
-
(2005)
Nat. Biotechnol
, vol.23
, Issue.2
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
-
26
-
-
77953897182
-
A novel mirna processing pathway independent of dicer requires argonaute2 catalytic activity
-
Cifuentes D, Xue H, Taylor DW et al. A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 328(5986), 1694-1698 (2010).
-
(2010)
Science
, vol.328
, Issue.5986
, pp. 1694-1698
-
-
Cifuentes, D.1
Xue, H.2
Taylor, D.W.3
-
27
-
-
78649894176
-
Dicer-independent, ago2-Mediated microrna biogenesis in vertebrates
-
Yang JS, Lai EC. Dicer-independent, Ago2-mediated microRNA biogenesis in vertebrates. Cell Cycle 9(22), 4455-4460 (2010).
-
(2010)
Cell Cycle
, vol.9
, Issue.22
, pp. 4455-4460
-
-
Yang, J.S.1
Lai, E.C.2
-
28
-
-
29144431656
-
A human, atp-independent, risc assembly machine fueled by pre-mirna
-
Maniataki E, Mourelatos Z. A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev. 19(24), 2979-2990 (2005).
-
(2005)
Genes Dev
, vol.19
, Issue.24
, pp. 2979-2990
-
-
Maniataki, E.1
Mourelatos, Z.2
-
29
-
-
84861448419
-
Precursor microrna-programmed silencing complex assembly pathways in mammals
-
Liu X, Jin DY, McManus MT, Mourelatos Z. Precursor microRNA-programmed silencing complex assembly pathways in mammals. Mol. Cell 46(4), 507-517 (2012).
-
(2012)
Mol. Cell
, vol.46
, Issue.4
, pp. 507-517
-
-
Liu, X.1
Jin, D.Y.2
McManus, M.T.3
Mourelatos, Z.4
-
30
-
-
75649133887
-
Expanded rna-binding activities of mammalian argonaute 2
-
Tan GS, Garchow BG, Liu X et al. Expanded RNA-binding activities of mammalian Argonaute 2. Nucleic Acids Res. 37(22), 7533-7545 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.22
, pp. 7533-7545
-
-
Tan, G.S.1
Garchow, B.G.2
Liu, X.3
-
31
-
-
79955436607
-
Clarifying mammalian risc assembly in vitro
-
Tan GS, Garchow BG, Liu X, Metzler D, Kiriakidou M. Clarifying mammalian RISC assembly in vitro. BMC. Mol. Biol. 12, 19 (2011).
-
(2011)
BMC. Mol. Biol
, vol.12
, pp. 19
-
-
Tan, G.S.1
Garchow, B.G.2
Liu, X.3
Metzler, D.4
Kiriakidou, M.5
-
32
-
-
84876057171
-
Global profiling of mirnas and the hairpin precursors: Insights into mirna processing and novel mirna discovery
-
Li N, You X, Chen T et al. Global profiling of miRNAs and the hairpin precursors: insights into miRNA processing and novel miRNA discovery. Nucleic Acids Res. 41(6), 3619-3634 (2013).
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.6
, pp. 3619-3634
-
-
Li, N.1
You, X.2
Chen, T.3
-
33
-
-
19644400971
-
Uridine addition after microrna-directed cleavage
-
Shen B, Goodman HM. Uridine addition after microRNA-directed cleavage. Science 306(5698), 997 (2004).
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 997
-
-
Shen, B.1
Goodman, H.M.2
-
34
-
-
84859969412
-
Functional parameters of dicer-independent microrna biogenesis
-
Yang JS, Maurin T, Lai EC. Functional parameters of Dicer-independent microRNA biogenesis. RNA 18(5), 945-957 (2012).
-
(2012)
RNA
, vol.18
, Issue.5
, pp. 945-957
-
-
Yang, J.S.1
Maurin, T.2
Lai, E.C.3
-
35
-
-
77956995245
-
Conserved vertebrate mir-451 provides a platform for dicer-independent, ago2- mediated microrna biogenesis
-
Yang JS, Maurin T, Robine N et al. Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2- mediated microRNA biogenesis. Proc. Natl Acad. Sci. USA 107(34), 15163-15168 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, Issue.34
, pp. 15163-15168
-
-
Yang, J.S.1
Maurin, T.2
Robine, N.3
-
36
-
-
84868097965
-
Micrornas associated with the different human argonaute proteins
-
Dueck A, Ziegler C, Eichner A, Berezikov E, Meister G. microRNAs associated with the different human Argonaute proteins. Nucleic Acids Res. 40(19), 9850-9862 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.19
, pp. 9850-9862
-
-
Dueck, A.1
Ziegler, C.2
Eichner, A.3
Berezikov, E.4
Meister, G.5
-
38
-
-
0036273940
-
Gene silencing using micro-Rna designed hairpins
-
McManus MT, Petersen CP, Haines BB, Chen J, Sharp PA. Gene silencing using micro-RNA designed hairpins. RNA 8(6), 842-850 (2002).
-
(2002)
RNA
, vol.8
, Issue.6
, pp. 842-850
-
-
McManus, M.T.1
Petersen, C.P.2
Haines, B.B.3
Chen, J.4
Sharp, P.A.5
-
39
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering rnas and short hairpin rnas and the effect on mammalian gene silencing
-
Harborth J, Elbashir SM, Vandenburgh K et al. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev. 13(2), 83-105 (2003).
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, Issue.2
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
-
40
-
-
75649143739
-
Minimal-length short hairpin rnas: The relationship of structure and rnai activity
-
Ge Q, Ilves H, Dallas A et al. Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity. RNA 16(1), 106-117 (2010).
-
(2010)
RNA
, vol.16
, Issue.1
, pp. 106-117
-
-
Ge, Q.1
Ilves, H.2
Dallas, A.3
-
41
-
-
79961102375
-
The effects of stem length and core placement on shrna activity
-
McIntyre GJ, Yu YH, Lomas M, Fanning GC. The effects of stem length and core placement on shRNA activity. BMC Mol. Biol. 12, 34 (2011).
-
(2011)
BMC Mol. Biol
, vol.12
, Issue.34
-
-
McIntyre, G.J.1
Yu, Y.H.2
Lomas, M.3
Fanning, G.C.4
-
42
-
-
84867564182
-
Right- and left-loop short shrnas have distinct and unusual mechanisms of gene silencing
-
Dallas A, Ilves H, Ge Q et al. Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing. Nucleic Acids Res. 40, 9255-9271 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 9255-9271
-
-
Dallas, A.1
Ilves, H.2
Ge, Q.3
-
43
-
-
77951298966
-
Optimization of shrna inhibitors by variation of the terminal loop sequence
-
Schopman NC, Liu YP, Konstantinova P, Ter Brake O, Berkhout B. Optimization of shRNA inhibitors by variation of the terminal loop sequence. Antiviral Res. 86(2), 204-211 (2010).
-
(2010)
Antiviral Res
, vol.86
, Issue.2
, pp. 204-211
-
-
Schopman, N.C.1
Liu, Y.P.2
Konstantinova, P.3
Ter Brake, O.4
Berkhout, B.5
-
44
-
-
17844363243
-
The contributions of dsrna structure to dicer specificity and efficiency
-
Vermeulen A, Behlen L, Reynolds A et al. The contributions of dsRNA structure to Dicer specificity and efficiency. RNA 11(5), 674-682 (2005).
-
(2005)
RNA
, vol.11
, Issue.5
, pp. 674-682
-
-
Vermeulen, A.1
Behlen, L.2
Reynolds, A.3
-
45
-
-
67649277689
-
The RNA-binding protein ksrp promotes the biogenesis of a subset of micrornas
-
Trabucchi M, Briata P, Garcia-Mayoral M et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 459(7249), 1010-1014 (2009).
-
(2009)
Nature
, vol.459
, Issue.7249
, pp. 1010-1014
-
-
Trabucchi, M.1
Briata, P.2
Garcia-Mayoral, M.3
-
46
-
-
84865073462
-
Functional selection of shrna loops from randomized retroviral libraries
-
Jensen SM, Schmitz A, Pedersen FS, Kjems J, Bramsen JB. Functional selection of shRNA loops from randomized retroviral libraries. PLoS ONE 7(8), e43095 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.8
-
-
Jensen, S.M.1
Schmitz, A.2
Pedersen, F.S.3
Kjems, J.4
Bramsen, J.B.5
-
47
-
-
70349887777
-
Combinatorial rnai against HIV 1 using extended short hairpin rnas
-
Liu YP, von Eije KJ, Schopman NC et al. Combinatorial RNAi against HIV 1 using extended short hairpin RNAs. Mol. Ther. 17(10), 1712-1723 (2009).
-
(2009)
Mol. Ther
, vol.17
, Issue.10
, pp. 1712-1723
-
-
Liu, Y.P.1
Von Eije, K.J.2
Schopman, N.C.3
-
48
-
-
84876030403
-
Dicer-independent processing of short hairpin rnas
-
Liu YP, Schopman NC, Berkhout B. Dicer-independent processing of short hairpin RNAs. Nucleic Acids Res. 41(6), 3723-3733 (2013).
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.6
, pp. 3723-3733
-
-
Liu, Y.P.1
Schopman, N.C.2
Berkhout, B.3
-
49
-
-
77957796766
-
Absence of dicer in monocytes and its regulation by HIV 1
-
Coley W, Van DR, Carpio L et al. Absence of DICER in monocytes and its regulation by HIV 1. J. Biol. Chem. 285(42), 31930-31943 (2010).
-
(2010)
J. Biol. Chem
, vol.285
, Issue.42
, pp. 31930-31943
-
-
Coley, W.1
Van, D.R.2
Carpio, L.3
-
50
-
-
0038419800
-
Induction of an interferon response by rnai vectors in mammalian cells
-
Bridge AJ, Pebernard S, Ducraux A, Nicoulaz AL, Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 34(3), 263-264 (2003).
-
(2003)
Nat. Genet
, vol.34
, Issue.3
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
51
-
-
84869037267
-
The loop position of shrnas and pre-mirnas is critical for the accuracy of dicer processing in vivo
-
Gu S, Jin L, Zhang Y et al. The loop position of shrnas and pre-mirnas is critical for the accuracy of dicer processing in vivo. Cell 151(4), 900-911 (2012).
-
(2012)
Cell
, vol.151
, Issue.4
, pp. 900-911
-
-
Gu, S.1
Jin, L.2
Zhang, Y.3
-
52
-
-
84868106469
-
Dicer partner proteins tune the length of mature mirnas in flies and mammals
-
Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD. Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell 151(3), 533-546 (2012).
-
(2012)
Cell
, vol.151
, Issue.3
, pp. 533-546
-
-
Fukunaga, R.1
Han, B.W.2
Hung, J.H.3
Xu, J.4
Weng, Z.5
Zamore, P.D.6
-
53
-
-
84880411222
-
Differential roles of human dicer-Binding proteins trbp and pact in small rna processing
-
Lee HY, Zhou K, Smith AM, Noland CL, Doudna JA. Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing. Nucleic Acids Res. 41(13), 6568-6576 (2013).
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.13
, pp. 6568-6576
-
-
Lee, H.Y.1
Zhou, K.2
Smith, A.M.3
Noland, C.L.4
Doudna, J.A.5
-
54
-
-
80655145885
-
Micrornas in viral gene regulation
-
Berkhout B, Jeang KT. MicroRNAs in viral gene regulation. Biochim. Biophys. Acta 1809(11-12), 587 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.180
, Issue.11-12
, pp. 587
-
-
Berkhout, B.1
Jeang, K.T.2
-
55
-
-
34848833981
-
Riscy business: Micrornas, pathogenesis, and viruses
-
Berkhout B, Jeang KT. RISCy business: microRNAs, pathogenesis, and viruses. J. Biol. Chem. 282(37), 26641-26645 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, Issue.37
, pp. 26641-26645
-
-
Berkhout, B.1
Jeang, K.T.2
-
56
-
-
34948817683
-
Cellular micrornas contribute to hiv 1 latency in resting primary CD4-t lymphocytes
-
Huang J, Wang F, Argyris E et al. Cellular microRNAs contribute to HIV 1 latency in resting primary CD4+ T lymphocytes. Nat. Med. 13(10), 1241-1247 (2007).
-
(2007)
Nat. Med
, vol.13
, Issue.10
, pp. 1241-1247
-
-
Huang, J.1
Wang, F.2
Argyris, E.3
-
57
-
-
84855295489
-
Deep sequencing of virus-Infected cells reveals hiv encoded small rnas
-
Schopman NC, Willemsen M, Liu YP et al. Deep sequencing of virus-infected cells reveals HIV encoded small RNAs. Nucleic Acids Res. 40(1), 414-427 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.1
, pp. 414-427
-
-
Schopman, N.C.1
Willemsen, M.2
Liu, Y.P.3
-
58
-
-
84870378445
-
Micrornas and hiv 1: Complex interactions
-
Klase Z, Houzet L, Jeang KT. MicroRNAs and HIV 1: complex interactions. J. Biol. Chem. 287(49), 40884-40890 (2012).
-
(2012)
J. Biol. Chem
, vol.287
, Issue.49
, pp. 40884-40890
-
-
Klase, Z.1
Houzet, L.2
Jeang, K.T.3
-
59
-
-
78650043619
-
Analysis of the roles of HIV derived micrornas
-
Narayanan A, Kehn-Hall K, Bailey C, Kashanchi F. Analysis of the roles of HIV derived microRNAs. Expert. Opin. Biol. Ther. 11(1), 17-29 (2011).
-
(2011)
Expert. Opin. Biol. Ther
, vol.11
, Issue.1
, pp. 17-29
-
-
Narayanan, A.1
Kehn-Hall, K.2
Bailey, C.3
Kashanchi, F.4
-
60
-
-
19344370167
-
Evidence that HIV 1 encodes an sirna and a suppressor of rna silencing
-
Bennasser Y, Le SY, Benkirane M, Jeang KT. Evidence that HIV 1 encodes an siRNA and a suppressor of RNA silencing. Immunity 22(5), 607-619 (2005).
-
(2005)
Immunity
, vol.22
, Issue.5
, pp. 607-619
-
-
Bennasser, Y.1
Le, S.Y.2
Benkirane, M.3
Jeang, K.T.4
-
61
-
-
61849174763
-
The ns3 protein of rice hoja blanca virus complements the rnai suppressor function of IVH1 tat
-
Schnettler E, de Vries W, Hemmes H et al. The NS3 protein of rice hoja blanca virus complements the RNAi suppressor function of HIV 1 Tat. EMBO Rep. 10(3), 258-263 (2009).
-
(2009)
EMBO Rep
, vol.10
, Issue.3
, pp. 258-263
-
-
Schnettler, E.1
De Vries, W.2
Hemmes, H.3
-
62
-
-
79960047585
-
Rnai-inducing lentiviral vectors for anti-HIV 1 gene therapy
-
Liu YP, Westerink JT, Ter Brake O, Berkhout B. RNAi-inducing lentiviral vectors for anti-HIV 1 gene therapy. Methods Mol. Biol. 721, 293-311 (2011).
-
(2011)
Methods Mol. Biol
, vol.721
, pp. 293-311
-
-
Liu, Y.P.1
Westerink, J.T.2
Ter Brake, O.3
Berkhout, B.4
-
63
-
-
84878031110
-
Selection of rnai-based inhibitors for anti-HIV gene therapy
-
Knoepfel SA, Centlivre M, Liu YP, Boutimah F, Berkhout B. Selection of RNAi-based inhibitors for anti-HIV gene therapy. World J. Virol. 1(3), 79-90 (2012).
-
(2012)
World J. Virol
, vol.1
, Issue.3
, pp. 79-90
-
-
Knoepfel, S.A.1
Centlivre, M.2
Liu, Y.P.3
Boutimah, F.4
Berkhout, B.5
-
64
-
-
49549117077
-
T cell-specific sirna delivery suppresses HIV 1 infection in humanized mice
-
Kumar P, Ban HS, Kim SS et al. T cell-specific siRNA delivery suppresses HIV 1 infection in humanized mice. Cell 134, 577-586 (2008).
-
(2008)
Cell
, vol.134
, pp. 577-586
-
-
Kumar, P.1
Ban, H.S.2
Kim, S.S.3
-
65
-
-
84856389509
-
RNA-based therapeutics: Current progress and future prospects
-
Burnett JC, Rossi JJ. RNA-based therapeutics: current progress and future prospects. Chem. Biol. 19(1), 60-71 (2012).
-
(2012)
Chem. Biol
, vol.19
, Issue.1
, pp. 60-71
-
-
Burnett, J.C.1
Rossi, J.J.2
-
66
-
-
84879867061
-
Lentiviral hematopoietic stem cell gene therapy in patients with wiskott-aldrich syndrome
-
Aiuti A, Biasco L, Scaramuzza S et al. Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome. Science 341, 865 (2013).
-
(2013)
Science
, vol.341
, pp. 865
-
-
Aiuti, A.1
Biasco, L.2
Scaramuzza, S.3
-
67
-
-
84879873039
-
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy
-
Biffi A, Montini E, Lorioli L et al. Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. Science 341, 864 (2013).
-
(2013)
Science
, vol.341
, pp. 864
-
-
Biffi, A.1
Montini, E.2
Lorioli, L.3
-
68
-
-
70449427834
-
Hematopoietic stem cell gene therapy with a lentiviral vector in x-linked adrenoleukodystrophy
-
Cartier N, Hacein-Bey-Abina S, Bartholomae CC et al. Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. Science 326(5954), 818-823 (2009).
-
(2009)
Science
, vol.326
, pp. 818-823
-
-
Cartier, N.1
Hacein-Bey-Abina, S.2
Bartholomae, C.C.3
-
69
-
-
77953642976
-
Titers of lentiviral vectors encoding shrnas and mirnas are reduced by different mechanisms that require distinct repair strategies
-
Liu YP, Vink MA, Westerink JT et al. Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies. RNA 16, 1328-1339 (2010).
-
(2010)
RNA
, vol.16
, pp. 1328-1339
-
-
Liu, Y.P.1
Vink, M.A.2
Westerink, J.T.3
-
70
-
-
34548574859
-
Lentiviral vectors that carry anti-hiv shrnas: Problems and solutions
-
Ter Brake O, Berkhout B. Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions. J. Gene Med. 9(9), 743-750 (2007).
-
(2007)
J. Gene Med
, vol.9
, Issue.9
, pp. 743-750
-
-
Ter Brake, O.1
Berkhout, B.2
-
71
-
-
34547843654
-
A systematic analysis of the effect of target rna structure on rna interference
-
Westerhout EM, Berkhout B. A systematic analysis of the effect of target RNA structure on RNA interference. Nucleic Acids Res. 35(13), 4322-4330 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.13
, pp. 4322-4330
-
-
Westerhout, E.M.1
Berkhout, B.2
-
72
-
-
84859441439
-
Shape-directed discovery of potent shrna inhibitors of hiv 1
-
Low JT, Knoepfel SA, Watts JM, Ter BO, Berkhout B, Weeks KM. SHAPE-directed discovery of potent shRNA inhibitors of HIV 1. Mol. Ther. 20, 820-828 (2012).
-
Mol. Ther
, vol.20
, Issue.2012
, pp. 820-828
-
-
Low, J.T.1
Knoepfel, S.A.2
Watts, J.M.3
Ter, B.O.4
Berkhout, B.5
Weeks, K.M.6
-
74
-
-
1242319384
-
Human immunodeficiency virus type 1 escapes from rna interference- mediated inhibition
-
Das AT, Brummelkamp TR, Westerhout EM et al. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 78(5), 2601-2605 (2004).
-
(2004)
J. Virol.
, vol.78
, Issue.5
, pp. 2601-2605
-
-
Das, A.T.1
Brummelkamp, T.R.2
Westerhout, E.M.3
-
75
-
-
33751001588
-
Silencing of hiv 1 with rna interference: A multiple shrna approach
-
Ter Brake O, Konstantinova P, Ceylan M, Berkhout B. Silencing of HIV 1 with RNA interference: a multiple shRNA approach. Mol. Ther. 14(6), 883-892 (2006).
-
(2006)
Mol. Ther
, vol.14
, Issue.6
, pp. 883-892
-
-
Ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
76
-
-
77955608799
-
Rna-based gene therapy for hiv with lentiviral vector-modified CD34-cells in patients undergoing transplantation for aids-related lymphoma
-
DiGiusto DL, Krishnan A, Li L et al. RNA-based gene therapy for HIV with lentiviral vector-modified CD34-cells in patients undergoing transplantation for AIDS-related lymphoma. Sci. Transl. Med. 2(36), 36ra43 (2010).
-
(2010)
Sci. Transl. Med
, vol.2
, Issue.36
-
-
Digiusto, D.L.1
Krishnan, A.2
Li, L.3
-
77
-
-
84859440756
-
HIV develops indirect cross-Resistance to combinatorial rnai targeting two distinct and spatially distant sites
-
Shah PS, Pham NP, Schaffer DV. HIV develops indirect cross-resistance to combinatorial RNAi targeting two distinct and spatially distant sites. Mol. Ther. 20(4), 840-848 (2012).
-
(2012)
Mol. Ther
, vol.20
, Issue.4
, pp. 840-848
-
-
Shah, P.S.1
Pham, N.P.2
Schaffer, D.V.3
-
78
-
-
84895501470
-
The impact of unprotected t cells in rnai-based gene therapy for hiv aids
-
Herrera-Carrillo E, Liu YP, Berkhout B. The impact of unprotected T cells in RNAi-based gene therapy for HIV AIDS. Mol. Ther. 22(3), 596-606 (2013).
-
(2013)
Mol. Ther
, vol.22
, Issue.3
, pp. 596-606
-
-
Herrera-Carrillo, E.1
Liu, Y.P.2
Berkhout, B.3
-
79
-
-
79953123523
-
Chemokine receptor 5 knockout strategies
-
Cannon P, June C. Chemokine receptor 5 knockout strategies. Curr. Opin. HIV AIDS 6(1), 74-79 (2011).
-
(2011)
Curr. Opin. HIV AIDS
, vol.6
, Issue.1
, pp. 74-79
-
-
Cannon, P.1
June, C.2
-
80
-
-
84878528467
-
Genomic editing of the hiv 1 coreceptor ccr5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases
-
Li L, Krymskaya L, Wang J et al. Genomic editing of the HIV 1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases. Mol. Ther. 21(6), 1259-1269 (2013).
-
(2013)
Mol. Ther
, vol.21
, Issue.6
, pp. 1259-1269
-
-
Li, L.1
Krymskaya, L.2
Wang, J.3
-
81
-
-
84878568502
-
Generation of an hiv resistant T-cell line by targeted 'stacking' of restriction factors
-
Voit RA, McMahon MA, Sawyer SL, Porteus MH. Generation of an HIV resistant T-cell line by targeted 'stacking' of restriction factors. Mol. Ther. 21(4), 786-795 (2013).
-
(2013)
Mol. Ther
, vol.21
, Issue.4
, pp. 786-795
-
-
Voit, R.A.1
McMahon, M.A.2
Sawyer, S.L.3
Porteus, M.H.4
-
82
-
-
34249336747
-
Safety and efficacy of a lentiviral vector containing three anti-hiv genes-CCR5 ribozyme, tat-rev sirna, and tar decoy-in scid-hu mouse-derived tcells
-
Anderson J, Li MJ, Palmer B et al. Safety and efficacy of a lentiviral vector containing three anti-HIV genes-CCR5 ribozyme, tat-rev siRNA, and TAR decoy-in SCID-hu mouse-derived T cells. Mol. Ther. 14, 1182-1188 (2007).
-
Mol. Ther
, vol.14
, Issue.2007
, pp. 1182-1188
-
-
Anderson, J.1
Li, M.J.2
Palmer, B.3
-
83
-
-
62049083710
-
Phase ii gene therapy trial of an anti-hiv ribozyme in autologous CD34-cells
-
Mitsuyasu RT, Merigan TC, Carr A et al. Phase II gene therapy trial of an anti-HIV ribozyme in autologous CD34-cells. Nat. Med. 15, 285-292 (2009).
-
(2009)
Nat. Med
, vol.15
, pp. 285-292
-
-
Mitsuyasu, R.T.1
Merigan, T.C.2
Carr, A.3
-
84
-
-
78751667739
-
An aptamer-sirna chimera suppresses HIV 1 viral loads and protects from helper CD4-tcell decline in humanized mice
-
Neff CP, Zhou J, Remling L et al. An aptamer-siRNA chimera suppresses HIV 1 viral loads and protects from helper CD4-Tcell decline in humanized mice. Sci. Transl. Med. 3(66), 66ra6 (2011).
-
(2011)
Sci. Transl. Med
, vol.3
, Issue.66
, pp. 66-66
-
-
Neff, C.P.1
Zhou, J.2
Remling, L.3
-
85
-
-
0035120510
-
Membrane-anchored peptide inhibits human immunodeficiency virus entry
-
Hildinger M, Dittmar MT, Schult-Dietrich P et al. Membrane-anchored peptide inhibits human immunodeficiency virus entry. J. Virol. 75(6), 3038-3042 (2001).
-
(2001)
J. Virol
, vol.75
, Issue.6
, pp. 3038-3042
-
-
Hildinger, M.1
Dittmar, M.T.2
Schult-Dietrich, P.3
-
86
-
-
39849108343
-
Lentiviral vector design for multiple shrna expression and durable hiv 1 inhibition
-
Ter Brake O, 't Hooft K, Liu YP, Centlivre M, von Eije KJ, Berkhout B. Lentiviral vector design for multiple shRNA expression and durable HIV 1 inhibition. Mol. Ther. 16(3), 557-564 (2008).
-
(2008)
Mol. Ther
, vol.16
, Issue.3
, pp. 557-564
-
-
Ter Brake, O.1
Hooft K, '.T.2
Liu, Y.P.3
Centlivre, M.4
Von Eije, K.J.5
Berkhout, B.6
-
87
-
-
77957807722
-
Deriving four functional anti-hiv sirnas from a single pol iii-generated transcript comprising two adjacent long hairpin rna precursors
-
Saayman S, Arbuthnot P, Weinberg MS. Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors. Nucleic Acids Res. 38(19), 6652-6663 (2010).
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.19
, pp. 6652-6663
-
-
Saayman, S.1
Arbuthnot, P.2
Weinberg, M.S.3
-
88
-
-
49749095063
-
The efficacy of generating three independent anti-hiv 1 sirnas from a single u6 rna pol iii-expressed long hairpin rna
-
Saayman S, Barichievy S, Capovilla A, Morris KV, Arbuthnot P, Weinberg MS. The efficacy of generating three independent anti-HIV 1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA. PLoS ONE 3(7), e2602 (2008).
-
(2008)
PLoS ONE
, vol.3
, Issue.7
-
-
Saayman, S.1
Barichievy, S.2
Capovilla, A.3
Morris, K.V.4
Arbuthnot, P.5
Weinberg, M.S.6
-
89
-
-
44349164025
-
Inhibition of hiv 1 by multiple sirnas expressed from a single microrna polycistron
-
Liu YP, Haasnoot J, Ter Brake O, Berkhout B, Konstantinova P. Inhibition of HIV 1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res. 36(9), 2811-2824 (2008).
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.9
, pp. 2811-2824
-
-
Liu, Y.P.1
Haasnoot, J.2
Ter Brake, O.3
Berkhout, B.4
Konstantinova, P.5
-
90
-
-
71049186345
-
RNA polymerase iii can drive polycistronic expression of functional interfering rnas designed to resemble micrornas
-
Snyder LL, Ahmed I, Steel LF. RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs. Nucleic Acids Res. 37(19), e127 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.19
-
-
Snyder, L.L.1
Ahmed, I.2
Steel, L.F.3
-
91
-
-
34848814237
-
Design of extended short hairpin rnas for hiv 1 inhibition
-
Liu YP, Haasnoot J, Berkhout B. Design of extended short hairpin RNAs for HIV 1 inhibition. Nucleic Acids Res. 35(17), 5683-5693 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.17
, pp. 5683-5693
-
-
Liu, Y.P.1
Haasnoot, J.2
Berkhout, B.3
-
92
-
-
33748850724
-
Inhibition of human immunodeficiency virus type 1 by rna interference using long-hairpin rna
-
Konstantinova P, De Vries W, Haasnoot J, Ter Brake O, De Haan P, Berkhout B. Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA. Gene Ther. 13(19), 1403-1413 (2006).
-
(2006)
Gene Ther
, vol.13
, Issue.19
, pp. 1403-1413
-
-
Konstantinova, P.1
De Vries, W.2
Haasnoot, J.3
Ter Brake, O.4
De Haan, P.5
Berkhout, B.6
-
93
-
-
83255187212
-
Current progress in the development of rnai-based therapeutics for HIV 1
-
Zhou J, Rossi JJ. Current progress in the development of RNAi-based therapeutics for HIV 1. Gene Ther. 18(12), 1134-1138 (2011).
-
(2011)
Gene Ther
, vol.18
, Issue.12
, pp. 1134-1138
-
-
Zhou, J.1
Rossi, J.J.2
-
94
-
-
84890379963
-
Preclinical in vivo evaluation of the safety of a multi-shrna-based gene therapy against HIV 1
-
Centlivre M, Legrand N, Klamer S et al. Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV 1. Mol. Ther. Nucleic Acids 2, e120 (2013).
-
(2013)
Mol. Ther. Nucleic Acids
, vol.2
-
-
Centlivre, M.1
Legrand, N.2
Klamer, S.3
-
95
-
-
84869840081
-
Rnase III-Independent microrna biogenesis in mammalian cells
-
Maurin T, Cazalla D, Yang S Jr, Bortolamiol-Becet D, Lai EC. RNase III-independent microRNA biogenesis in mammalian cells. RNA 18(12), 2166-2173 (2012).
-
(2012)
RNA
, vol.18
, Issue.12
, pp. 2166-2173
-
-
Maurin, T.1
Cazalla, D.2
Yang Jr., S.3
Bortolamiol-Becet, D.4
Lai, E.C.5
-
96
-
-
84876374428
-
Deep sequencing of small rnas identifies canonical and non-canonical mirna and endogenous sirnas in mammalian somatic tissues
-
Castellano L, Stebbing J. Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues. Nucleic Acids Res. 41(5), 3339-3351 (2013).
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.5
, pp. 3339-3351
-
-
Castellano, L.1
Stebbing, J.2
|