Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity

RNA

Volumn 20, Issue 9, 2014, Pages 1410-1418

  Herrera Carrillo, Elena ^a   Harwig, Alex ^a   Liu, Ying Poi ^a   Berkhout, Ben ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Ago2; Dicer; Dicer independent shRNA; miR 451; RNAi; shRNA design

Indexed keywords

AGO2; DICER; DICER-INDEPENDENT SHRNA; MIR-451; RNAI; SHRNA DESIGN;

ARGONAUTE PROTEINS; BASE PAIRING; BASE SEQUENCE; BINDING SITES; DEAD-BOX RNA HELICASES; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HEK293 CELLS; HUMANS; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; RIBONUCLEASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, SMALL INTERFERING;

EID: 84906851063     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.043950.113     Document Type: Article

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