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Volumn 9, Issue 13, 2002, Pages 889-897

Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection

Author keywords

Gene therapy; HIV 1; Lentiviral vector; Quantitative real time PCR; RANTES intrakine; T lymphocytes

Indexed keywords

CD28 ANTIGEN; CD34 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; ELONGATION FACTOR 1ALPHA; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; PLASMID DNA; RANTES; VIRUS DNA;

EID: 0036290645     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301711     Document Type: Article
Times cited : (35)

References (44)
  • 1
    • 0029802605 scopus 로고    scopus 로고
    • Chemokines and HIV-1 second receptors. Confluence of two fields generates optimism in AIDS research
    • (1996) Nat. Med , vol.2 , pp. 1293-1300
    • D'Souza, M.P.1    Harden, V.A.2
  • 3
    • 15844419153 scopus 로고    scopus 로고
    • Identification of a major co-receptor for primary isolates of HIV-1
    • (1996) Nature , vol.381 , pp. 661-666
    • Deng, H.1
  • 4
    • 0005014748 scopus 로고    scopus 로고
    • The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
    • (1996) Cell , vol.85 , pp. 1135-1148
    • Choe, H.1
  • 5
    • 0030018156 scopus 로고    scopus 로고
    • CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
    • (1996) Science , vol.272 , pp. 1955-1958
    • Alkhatib, G.1
  • 6
    • 0030604727 scopus 로고    scopus 로고
    • A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3 and CKR-2b as fusion cofactors
    • (1996) Cell , vol.85 , pp. 1149-1158
    • Doranz, B.J.1
  • 7
    • 15844389650 scopus 로고    scopus 로고
    • + cells is mediated by the chemokine receptor CC-CKR-5
    • (1996) Nature , vol.381 , pp. 667-673
    • Dragic, T.1
  • 9
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1
  • 10
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene
    • Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study (published erratum appears in Science 1996; 274: 1069)
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1
  • 11
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • (1996) Nature , vol.382 , pp. 722-725
    • Samson, M.1
  • 12
    • 16044367526 scopus 로고    scopus 로고
    • The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
    • (1996) Nat. Med , vol.2 , pp. 1240-1243
    • Huang, Y.1
  • 13
    • 8244227329 scopus 로고    scopus 로고
    • Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: Studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk
    • (1997) Mol. Med , vol.3 , pp. 23-36
    • Zimmerman, P.A.1
  • 14
    • 0031041571 scopus 로고    scopus 로고
    • The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression
    • (1997) Nat. Med , vol.3 , pp. 338-340
    • Michael, N.L.1
  • 15
    • 0030881882 scopus 로고    scopus 로고
    • Phenotypic knockout of HIV type 1 chemokine coreceptor CCR-5 by intrakines as potential therapeutic approach for HIV-1 infection
    • Proc Natl Acad Sci USA
    • (1997) , vol.94 , pp. 11567-11572
    • Yang, A.G.1
  • 16
    • 0032552429 scopus 로고    scopus 로고
    • Anti-HIV type 1 activity of wild-type and functional defective RANTES intrakine in primary human lymphocytes
    • (1998) Hum. Gene Ther , vol.9 , pp. 2005-2018
    • Yang, A.G.1
  • 17
    • 0034672356 scopus 로고    scopus 로고
    • The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells
    • (2000) Blood , vol.96 , pp. 4103-4110
    • Sirven, A.1
  • 18
    • 0034669932 scopus 로고    scopus 로고
    • High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors
    • (2000) Blood , vol.96 , pp. 3392-3398
    • Salmon, P.1
  • 19
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1
  • 20
    • 0034135980 scopus 로고    scopus 로고
    • Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system
    • (2000) Mol. Ther , vol.1 , pp. 171-179
    • Schroers, R.1
  • 21
    • 0034985720 scopus 로고    scopus 로고
    • Enhanced transgene expression in cord blood CD34(+)-derived hematopoietic cells, including developing T cells and NOD/SCID mouse repopulating cells, following transduction with modified trip lentiviral vectors
    • (2001) Mol. Ther , vol.3 , pp. 438-448
    • Sirven, A.1
  • 25
    • 8944232102 scopus 로고    scopus 로고
    • + T cell proliferation in HIV-positive patients as a result of CD28 costimulation
    • (1996) Science , vol.272 , pp. 1939-1943
    • Levine, B.L.1
  • 26
    • 0028097848 scopus 로고
    • Ckat: A high-efficiency retroviral transduction system for primary human T lymphocytes
    • (1994) Blood , vol.83 , pp. 43-50
    • Finer, M.H.1
  • 27
    • 0035125883 scopus 로고    scopus 로고
    • Normalized quantification by real-time PCR of Epstein-Barr virus load in patients at risk for posttransplant lymphoproliferative disorders
    • (2001) J. Clin. Microbiol , vol.39 , pp. 564-569
    • Jabs, W.J.1
  • 28
    • 0032547101 scopus 로고    scopus 로고
    • HIV treatment failure: Testing for HIV resistance in clinical practice
    • (1998) Science , vol.280 , pp. 1871-1873
    • Perrin, L.1    Telenti, A.2
  • 31
    • 0027970297 scopus 로고
    • Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cells
    • Proc Natl Acad Sci USA
    • (1994) , vol.91 , pp. 11581-11585
    • Woffendin, C.1
  • 32
    • 0030594579 scopus 로고    scopus 로고
    • Gene therapy for AIDS using retroviral mediated gene transfer to deliver HIV-1 antisense TAR and transdominant Rev protein genes to syngeneic lymphocytes in HIV-1 infected identical twins
    • (1996) Hum. Gene Ther , vol.7 , pp. 1281-1306
    • Morgan, R.A.1    Walker, R.2
  • 33
    • 0034254611 scopus 로고    scopus 로고
    • Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects
    • (2000) Blood , vol.96 , pp. 785-793
    • Mitsuyasu, R.T.1
  • 34
    • 0034958582 scopus 로고    scopus 로고
    • Defective lentiviral vectors are efficiently trafficked by HIV-1 and inhibit its replication
    • (2001) Mol. Ther , vol.3 , pp. 928-939
    • Klimatcheva, E.1
  • 35
    • 0035081424 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by HIV-1-based lentivirus vectors expressing transdominant Rev
    • (2001) J. Virol , vol.75 , pp. 3590-3599
    • Mautino, M.R.1    Keiser, N.2    Morgan, R.A.3
  • 36
    • 0034759534 scopus 로고    scopus 로고
    • Lentiviral vectors approach the clinic but fall back: National Institutes of Health Recombinant DNA Advisory Committee review of a first clinical protocol for use of a lentiviral vector
    • (2001) Mol. Ther , vol.4 , pp. 282-283
    • Podsakoff, G.M.1
  • 38
    • 0030830661 scopus 로고    scopus 로고
    • Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
    • (1997) J. Exp. Med , vol.186 , pp. 1383-1388
    • Schols, D.1
  • 39
    • 0030780377 scopus 로고    scopus 로고
    • A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
    • (1997) J. Exp. Med , vol.186 , pp. 1389-1393
    • Murakami, T.1
  • 40
    • 0030773515 scopus 로고    scopus 로고
    • A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
    • (1997) J. Exp. Med , vol.186 , pp. 1395-1400
    • Doranz, B.J.1
  • 41
    • 0031891516 scopus 로고    scopus 로고
    • AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
    • (1998) Nat. Med , vol.4 , pp. 72-77
    • Donzella, G.A.1
  • 42
    • 0035119311 scopus 로고    scopus 로고
    • Lentivirus-mediated gene transfer in primary T cells is enhanced by a central DNA flap
    • (2001) Gene Therapy , vol.8 , pp. 190-198
    • Dardalhon, V.1
  • 43
    • 0031877513 scopus 로고    scopus 로고
    • Genetic co-inactivation of macrophage- and T-tropic HIV-1 chemokine coreceptors CCR-5 and CXCR-4 by intrakines
    • (1998) Gene Therapy , vol.5 , pp. 984-994
    • Bai, X.1
  • 44
    • 0035059676 scopus 로고    scopus 로고
    • Quantification of human immunodeficiency virus type 1 proviral load by a taqman real-time pcr assay
    • (2001) J. Clin. Microbiol , vol.39 , pp. 1303-1310
    • Desire, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.