-
1
-
-
42449160202
-
Requirements for gene silencing mediated by U1 snRNA binding to a target sequence
-
Abad X., Vera M., Jung S.P., Oswald E., Romero I., Amin V., Fortes P., Gunderson S.I. Requirements for gene silencing mediated by U1 snRNA binding to a target sequence. Nucleic Acids Res. 2008, 36:2338-2352.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 2338-2352
-
-
Abad, X.1
Vera, M.2
Jung, S.P.3
Oswald, E.4
Romero, I.5
Amin, V.6
Fortes, P.7
Gunderson, S.I.8
-
2
-
-
77955236073
-
Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression
-
Abad X., Razquin N., Abad A., Fortes P. Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression. Nucleic Acids Res. 2010, 38:e136.
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Abad, X.1
Razquin, N.2
Abad, A.3
Fortes, P.4
-
3
-
-
34249336747
-
Safety and efficacy of a lentiviral vector containing three anti-HIV genes-CCR5 ribozyme, tat-rev siRNA, and TAR decoy-in SCID-hu mouse-derived T cells
-
Anderson J., Li M.J., Palmer B., Remling L., Li S., Yam P., Yee J.K., Rossi J., Zaia J., Akkina R. Safety and efficacy of a lentiviral vector containing three anti-HIV genes-CCR5 ribozyme, tat-rev siRNA, and TAR decoy-in SCID-hu mouse-derived T cells. Mol. Ther. 2007, 14:1182-1188.
-
(2007)
Mol. Ther.
, vol.14
, pp. 1182-1188
-
-
Anderson, J.1
Li, M.J.2
Palmer, B.3
Remling, L.4
Li, S.5
Yam, P.6
Yee, J.K.7
Rossi, J.8
Zaia, J.9
Akkina, R.10
-
4
-
-
0041903758
-
Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages
-
Banerjea A., Li M.J., Bauer G., Remling L., Lee N.S., Rossi J., Akkina R. Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages. Mol. Ther. 2003, 8:62-71.
-
(2003)
Mol. Ther.
, vol.8
, pp. 62-71
-
-
Banerjea, A.1
Li, M.J.2
Bauer, G.3
Remling, L.4
Lee, N.S.5
Rossi, J.6
Akkina, R.7
-
5
-
-
0020596551
-
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
-
Barré-Sinoussi F., Chermann J.C., Rey P., Nugeyre M.T., Chamaret S., Gruest J., Dauguet C., Axler-Blin C., Vezinet-Brun F., Rouzioux C., Rozenbaum W., Montagnier L. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 1983, 220:868-871.
-
(1983)
Science
, vol.220
, pp. 868-871
-
-
Barré-Sinoussi, F.1
Chermann, J.C.2
Rey, P.3
Nugeyre, M.T.4
Chamaret, S.5
Gruest, J.6
Dauguet, C.7
Axler-Blin, C.8
Vezinet-Brun, F.9
Rouzioux, C.10
Rozenbaum, W.11
Montagnier, L.12
-
6
-
-
0035083167
-
Reduction of target gene expression by a modified U1 snRNA
-
Beckley S.A., Liu P., Stover M.L., Gunderson S.I., Lichtler A.C., Rowe D.W. Reduction of target gene expression by a modified U1 snRNA. Mol. Cell Biol. 2001, 21:2815-2825.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 2815-2825
-
-
Beckley, S.A.1
Liu, P.2
Stover, M.L.3
Gunderson, S.I.4
Lichtler, A.C.5
Rowe, D.W.6
-
7
-
-
33745103496
-
The retrovirus RNA trafficking granule: from birth to maturity
-
Cochrane A.W., McNally M.T., Mouland A.J. The retrovirus RNA trafficking granule: from birth to maturity. Retrovirology 2006, 3:18.
-
(2006)
Retrovirology
, vol.3
, pp. 18
-
-
Cochrane, A.W.1
McNally, M.T.2
Mouland, A.J.3
-
8
-
-
80052452885
-
The HIV-1 Tat protein has a versatile role in activating viral transcription
-
Das A.T., Harwig A., Berkhout B. The HIV-1 Tat protein has a versatile role in activating viral transcription. J. Virol. 2011, 85:9506-9516.
-
(2011)
J. Virol.
, vol.85
, pp. 9506-9516
-
-
Das, A.T.1
Harwig, A.2
Berkhout, B.3
-
9
-
-
77955608799
-
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma
-
DiGiusto D.L., Krishnan A., Li L., Li H., Li S., Rao A., Mi S., Yam P., Stinson S., Kalos M., Alvarnas J., Lacey S.F., Yee J.K., Li M., Couture L., Hsu D., Forman S.J., Rossi J.J., Zaia J.A. RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Sci. Transl. Med. 2010, 2:36ra43.
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
DiGiusto, D.L.1
Krishnan, A.2
Li, L.3
Li, H.4
Li, S.5
Rao, A.6
Mi, S.7
Yam, P.8
Stinson, S.9
Kalos, M.10
Alvarnas, J.11
Lacey, S.F.12
Yee, J.K.13
Li, M.14
Couture, L.15
Hsu, D.16
Forman, S.J.17
Rossi, J.J.18
Zaia, J.A.19
-
10
-
-
0038492463
-
Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA
-
Fortes P., Cuevas Y., Guan F., Liu P., Pentlicky S., Jung S.P., Martinez-Chantar M.L., Prieto J., Rowe D., Gunderson S.I. Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA. Proc. Natl Acad. Sci. USA 2003, 100:8264-8269.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 8264-8269
-
-
Fortes, P.1
Cuevas, Y.2
Guan, F.3
Liu, P.4
Pentlicky, S.5
Jung, S.P.6
Martinez-Chantar, M.L.7
Prieto, J.8
Rowe, D.9
Gunderson, S.I.10
-
11
-
-
0031610367
-
U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase
-
Gunderson S.I., Polycarpou-Schwarz M., Mattaj I.W. U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol. Cell 1998, 1:255-264.
-
(1998)
Mol. Cell
, vol.1
, pp. 255-264
-
-
Gunderson, S.I.1
Polycarpou-Schwarz, M.2
Mattaj, I.W.3
-
12
-
-
42649122295
-
Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells
-
Jankowska A., Gunderson S.I., Andrusiewicz M., Burczynska B., Szczerba A., Jarmolowski A., Nowak-Markwitz E., Warchol J.B. Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells. Mol. Cancer 2008, 7:26.
-
(2008)
Mol. Cancer
, vol.7
, pp. 26
-
-
Jankowska, A.1
Gunderson, S.I.2
Andrusiewicz, M.3
Burczynska, B.4
Szczerba, A.5
Jarmolowski, A.6
Nowak-Markwitz, E.7
Warchol, J.B.8
-
13
-
-
0034030611
-
Functional differences between the long terminal repeat transcriptional promoters of HIV-1 subtypes A through G
-
Jeeninga R.E., Hoogenkamp M., Armand-Ugon M., de Baar M., Verhoef K., Berkhout B. Functional differences between the long terminal repeat transcriptional promoters of HIV-1 subtypes A through G. J. Virol. 2000, 74:3740-3751.
-
(2000)
J. Virol.
, vol.74
, pp. 3740-3751
-
-
Jeeninga, R.E.1
Hoogenkamp, M.2
Armand-Ugon, M.3
de Baar, M.4
Verhoef, K.5
Berkhout, B.6
-
14
-
-
0037037333
-
Hyperstable U1snRNA complementary to the K-ras transcripts induces cell death in pancreatic cancer cells
-
Kato K., Hitomi Y., Imamura K., Esumi H. Hyperstable U1snRNA complementary to the K-ras transcripts induces cell death in pancreatic cancer cells. Br. J. Cancer 2002, 87:898-904.
-
(2002)
Br. J. Cancer
, vol.87
, pp. 898-904
-
-
Kato, K.1
Hitomi, Y.2
Imamura, K.3
Esumi, H.4
-
15
-
-
80052601221
-
AAV-mediated in vivo knockdown of luciferase using combinatorial RNAi and U1i
-
Koornneef A., van Logtenstein R., Timmermans E., Pisas L., Blits B., Abad X., Fortes P., Petry H., Konstantinova P., Ritsema T. AAV-mediated in vivo knockdown of luciferase using combinatorial RNAi and U1i. Gene Ther. 2011, 18:929-935.
-
(2011)
Gene Ther.
, vol.18
, pp. 929-935
-
-
Koornneef, A.1
van Logtenstein, R.2
Timmermans, E.3
Pisas, L.4
Blits, B.5
Abad, X.6
Fortes, P.7
Petry, H.8
Konstantinova, P.9
Ritsema, T.10
-
16
-
-
0036829065
-
U1 snRNA associates with TFIIH and regulates transcriptional initiation
-
Kwek K.Y., Murphy S., Furger A., Thomas B., O'Gorman W., Kimura H., Proudfoot N.J., Akoulitchev A. U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat. Struct. Biol. 2002, 9:800-805.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 800-805
-
-
Kwek, K.Y.1
Murphy, S.2
Furger, A.3
Thomas, B.4
O'Gorman, W.5
Kimura, H.6
Proudfoot, N.J.7
Akoulitchev, A.8
-
17
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
Levine B.L., Humeau L.M., Boyer J., MacGregor R.R., Rebello T., Lu X., Binder G.K., Slepushkin V., Lemiale F., Mascola J.R., Bushman F.D., Dropulic B., June C.H. Gene transfer in humans using a conditionally replicating lentiviral vector. Proc. Natl Acad. Sci. USA 2006, 103:17372-17377.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
MacGregor, R.R.4
Rebello, T.5
Lu, X.6
Binder, G.K.7
Slepushkin, V.8
Lemiale, F.9
Mascola, J.R.10
Bushman, F.D.11
Dropulic, B.12
June, C.H.13
-
18
-
-
27744605569
-
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy
-
Li M.J., Kim J., Li S., Zaia J., Yee J.K., Anderson J., Akkina R., Rossi J.J. Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy. Mol. Ther. 2005, 12:900-909.
-
(2005)
Mol. Ther.
, vol.12
, pp. 900-909
-
-
Li, M.J.1
Kim, J.2
Li, S.3
Zaia, J.4
Yee, J.K.5
Anderson, J.6
Akkina, R.7
Rossi, J.J.8
-
19
-
-
2542643913
-
Modified U1 snRNA suppresses expression of a targeted endogenous RNA by inhibiting polyadenylation of the transcript
-
Liu P., Kronenberg M., Jiang X., Rowe D. Modified U1 snRNA suppresses expression of a targeted endogenous RNA by inhibiting polyadenylation of the transcript. Nucleic Acids Res. 2004, 32:1512-1517.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1512-1517
-
-
Liu, P.1
Kronenberg, M.2
Jiang, X.3
Rowe, D.4
-
20
-
-
70349887777
-
Combinatorial RNAi against HIV-1 using extended short hairpin RNAs
-
Liu Y.P., von Eije K.J., Schopman N.C., Westerink J.T., Ter Brake O., Haasnoot J., Berkhout B. Combinatorial RNAi against HIV-1 using extended short hairpin RNAs. Mol. Ther. 2009, 17:1712-1723.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1712-1723
-
-
Liu, Y.P.1
von Eije, K.J.2
Schopman, N.C.3
Westerink, J.T.4
Ter Brake, O.5
Haasnoot, J.6
Berkhout, B.7
-
21
-
-
20844445774
-
Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol
-
Lu X., Humeau L., Slepushkin V., Binder G., Yu Q., Slepushkina T., Chen Z., Merling R., Davis B., Chang Y.N., Dropulic B. Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol. J. Gene Med. 2004, 6:963-973.
-
(2004)
J. Gene Med.
, vol.6
, pp. 963-973
-
-
Lu, X.1
Humeau, L.2
Slepushkin, V.3
Binder, G.4
Yu, Q.5
Slepushkina, T.6
Chen, Z.7
Merling, R.8
Davis, B.9
Chang, Y.N.10
Dropulic, B.11
-
22
-
-
2942639506
-
Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance
-
Lu X., Yu Q., Binder G.K., Chen Z., Slepushkina T., Rossi J., Dropulic B. Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance. J. Virol. 2004, 78:7079-7088.
-
(2004)
J. Virol.
, vol.78
, pp. 7079-7088
-
-
Lu, X.1
Yu, Q.2
Binder, G.K.3
Chen, Z.4
Slepushkina, T.5
Rossi, J.6
Dropulic, B.7
-
23
-
-
78649406554
-
Excessive RNA splicing and inhibition of HIV-1 replication induced by modified U1 small nuclear RNAs
-
Mandal D., Feng Z., Stoltzfus C.M. Excessive RNA splicing and inhibition of HIV-1 replication induced by modified U1 small nuclear RNAs. J. Virol. 2010, 84:12790-12800.
-
(2010)
J. Virol.
, vol.84
, pp. 12790-12800
-
-
Mandal, D.1
Feng, Z.2
Stoltzfus, C.M.3
-
24
-
-
0035932984
-
In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
-
Marzio G., Verhoef K., Vink M., Berkhout B. In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies. Proc. Natl Acad. Sci. USA 2001, 98:6342-6347.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 6342-6347
-
-
Marzio, G.1
Verhoef, K.2
Vink, M.3
Berkhout, B.4
-
25
-
-
0036191195
-
Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription
-
Marzio G., Vink M., Verhoef K., de Ronde A., Berkhout B. Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription. J. Virol. 2002, 76:3084-3088.
-
(2002)
J. Virol.
, vol.76
, pp. 3084-3088
-
-
Marzio, G.1
Vink, M.2
Verhoef, K.3
de Ronde, A.4
Berkhout, B.5
-
26
-
-
62049083710
-
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34(+) cells
-
Mitsuyasu R.T., Merigan T.C., Carr A., Zack J.A., Winters M.A., Workman C., Bloch M., Lalezari J., Becker S., Thornton L., Akil B., Khanlou H., Finlayson R., McFarlane R., Smith D.E., Garsia R., Ma D., Law M., Murray J.M., von Kalle C., Ely J.A., Patino S.M., Knop A.E., Wong P., Todd A.V., Haughton M., Fuery C., Macpherson J.L., Symonds G.P., Evans L.A., Pond S.M., Cooper D.A. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34(+) cells. Nat. Med. 2009, 15:285-292.
-
(2009)
Nat. Med.
, vol.15
, pp. 285-292
-
-
Mitsuyasu, R.T.1
Merigan, T.C.2
Carr, A.3
Zack, J.A.4
Winters, M.A.5
Workman, C.6
Bloch, M.7
Lalezari, J.8
Becker, S.9
Thornton, L.10
Akil, B.11
Khanlou, H.12
Finlayson, R.13
McFarlane, R.14
Smith, D.E.15
Garsia, R.16
Ma, D.17
Law, M.18
Murray, J.M.19
von Kalle, C.20
Ely, J.A.21
Patino, S.M.22
Knop, A.E.23
Wong, P.24
Todd, A.V.25
Haughton, M.26
Fuery, C.27
Macpherson, J.L.28
Symonds, G.P.29
Evans, L.A.30
Pond, S.M.31
Cooper, D.A.32
more..
-
27
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
Morris K.V., Chan S.W., Jacobsen S.E., Looney D.J. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 2004, 305:1289-1292.
-
(2004)
Science
, vol.305
, pp. 1289-1292
-
-
Morris, K.V.1
Chan, S.W.2
Jacobsen, S.E.3
Looney, D.J.4
-
28
-
-
41949088960
-
U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency
-
Pinotti M., Rizzotto L., Balestra D., Lewandowska M.A., Cavallari N., Marchetti G., Bernardi F., Pagani F. U1-snRNA-mediated rescue of mRNA processing in severe factor VII deficiency. Blood 2008, 111:2681-2684.
-
(2008)
Blood
, vol.111
, pp. 2681-2684
-
-
Pinotti, M.1
Rizzotto, L.2
Balestra, D.3
Lewandowska, M.A.4
Cavallari, N.5
Marchetti, G.6
Bernardi, F.7
Pagani, F.8
-
29
-
-
0027494083
-
Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity
-
Purcell D.F.J., Martin M.A. Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity. J. Virol. 1993, 67:6365-6378.
-
(1993)
J. Virol.
, vol.67
, pp. 6365-6378
-
-
Purcell, D.F.J.1
Martin, M.A.2
-
30
-
-
0024603237
-
A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein
-
Query C.C., Bentley R.C., Keene J.D. A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein. Cell 1989, 57:89-101.
-
(1989)
Cell
, vol.57
, pp. 89-101
-
-
Query, C.C.1
Bentley, R.C.2
Keene, J.D.3
-
31
-
-
0025098474
-
Exon definition may facilitate splice site selection in RNAs with multiple exons
-
Robberson B.L., Cote G.J., Berget S.M. Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol. Cell Biol. 1990, 10:84-94.
-
(1990)
Mol. Cell Biol.
, vol.10
, pp. 84-94
-
-
Robberson, B.L.1
Cote, G.J.2
Berget, S.M.3
-
32
-
-
0029796604
-
Involvement of U1 small nuclear ribonucleoproteins (snRNP) in 5' splice site-U1 snRNP interaction
-
Rossi F., Forne T., Antoine E., Tazi J., Brunel C., Cathala G. Involvement of U1 small nuclear ribonucleoproteins (snRNP) in 5' splice site-U1 snRNP interaction. J. Biol. Chem. 1996, 271:23985-23991.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23985-23991
-
-
Rossi, F.1
Forne, T.2
Antoine, E.3
Tazi, J.4
Brunel, C.5
Cathala, G.6
-
33
-
-
30644466345
-
Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology
-
Ruijter J.M., Thygesen H.H., Schoneveld O.J., Das A.T., Berkhout B., Lamers W.H. Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology. Retrovirology 2006, 3:1-8.
-
(2006)
Retrovirology
, vol.3
, pp. 1-8
-
-
Ruijter, J.M.1
Thygesen, H.H.2
Schoneveld, O.J.3
Das, A.T.4
Berkhout, B.5
Lamers, W.H.6
-
34
-
-
33846676217
-
Use of modified U1 snRNAs to inhibit HIV-1 replication
-
Sajic R., Lee K., Asai K., Sakac D., Branch D.R., Upton C., Cochrane A. Use of modified U1 snRNAs to inhibit HIV-1 replication. Nucleic Acids Res. 2007, 35:247-255.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 247-255
-
-
Sajic, R.1
Lee, K.2
Asai, K.3
Sakac, D.4
Branch, D.R.5
Upton, C.6
Cochrane, A.7
-
35
-
-
0024851833
-
Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA
-
Scherly D., Boelens W., van Venrooij W.J., Dathan N.A., Hamm J., Mattaj I.W. Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA. EMBO J. 1989, 8:4163-4170.
-
(1989)
EMBO J.
, vol.8
, pp. 4163-4170
-
-
Scherly, D.1
Boelens, W.2
van Venrooij, W.J.3
Dathan, N.A.4
Hamm, J.5
Mattaj, I.W.6
-
36
-
-
0024986753
-
Binding specificity determinants of U1A and U2B" proteins
-
Scherly D., Boelens W., Dathan N.A., Kambach C., van Venrooij W.J., Mattaj I.W. Binding specificity determinants of U1A and U2B" proteins. Mol. Biol. Rep. 1990, 14:181-182.
-
(1990)
Mol. Biol. Rep.
, vol.14
, pp. 181-182
-
-
Scherly, D.1
Boelens, W.2
Dathan, N.A.3
Kambach, C.4
van Venrooij, W.J.5
Mattaj, I.W.6
-
37
-
-
0036116344
-
Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes
-
Seppen J., Rijnberg M., Cooreman M.P., Oude Elferink R.P. Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes. J. Hepatol. 2002, 36:459-465.
-
(2002)
J. Hepatol.
, vol.36
, pp. 459-465
-
-
Seppen, J.1
Rijnberg, M.2
Cooreman, M.P.3
Oude Elferink, R.P.4
-
38
-
-
31044436469
-
Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region
-
Suzuki K., Shijuuku T., Fukamachi T., Zaunders J., Guillemin G., Cooper D., Kelleher A. Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region. J. RNAi Gene Silencing 2005, 1:66-78.
-
(2005)
J. RNAi Gene Silencing
, vol.1
, pp. 66-78
-
-
Suzuki, K.1
Shijuuku, T.2
Fukamachi, T.3
Zaunders, J.4
Guillemin, G.5
Cooper, D.6
Kelleher, A.7
-
39
-
-
59749104368
-
Therapeutic strategy to rescue mutation-induced exon skipping in rhodopsin by adaptation of U1 snRNA
-
Tanner G., Glaus E., Barthelmes D., Ader M., Fleischhauer J., Pagani F., Berger W., Neidhardt J. Therapeutic strategy to rescue mutation-induced exon skipping in rhodopsin by adaptation of U1 snRNA. Hum. Mutat. 2009, 30:255-263.
-
(2009)
Hum. Mutat.
, vol.30
, pp. 255-263
-
-
Tanner, G.1
Glaus, E.2
Barthelmes, D.3
Ader, M.4
Fleischhauer, J.5
Pagani, F.6
Berger, W.7
Neidhardt, J.8
-
40
-
-
70349448020
-
Development of an RNAi-based gene therapy against HIV-1
-
In: Kurreck, J. (Ed.), Therapeutic Oligonucleotides RSC Publishing, Cambridge
-
Ter Brake, O., Berkhout, B., 2008. Development of an RNAi-based gene therapy against HIV-1. In: Kurreck, J. (Ed.), Therapeutic Oligonucleotides RSC Publishing, Cambridge, pp. 296-311.
-
(2008)
, pp. 296-311
-
-
Ter Brake, O.1
Berkhout, B.2
-
41
-
-
33751001588
-
Silencing of HIV-1 with RNA interference. A multiple shRNA approach
-
Ter Brake O., Konstantinova P., Ceylan M., Berkhout B. Silencing of HIV-1 with RNA interference. A multiple shRNA approach. Mol. Ther. 2006, 14:883-892.
-
(2006)
Mol. Ther.
, vol.14
, pp. 883-892
-
-
Ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
42
-
-
39849108343
-
Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition
-
Ter Brake, O., 't Hooft, K., Liu, Y.P., Centlivre, M., von Eije, K.J., erkhout, B., 2008. Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition. Mol. Ther. 16, 557-564.
-
(2008)
Mol. Ther.
, vol.16
, pp. 557-564
-
-
Ter Brake, O.1
't Hooft, K.2
Liu, Y.P.3
Centlivre, M.4
von Eije, K.J.5
erkhout, B.6
-
43
-
-
58149458865
-
Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)(c)(-/-)) mouse model
-
Ter Brake O., Legrand N., von Eije K.J., Centlivre M., Spits H., Weijer K., Blom B., Berkhout B. Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)(c)(-/-)) mouse model. Gene Ther. 2009, 16:148-153.
-
(2009)
Gene Ther.
, vol.16
, pp. 148-153
-
-
Ter Brake, O.1
Legrand, N.2
von Eije, K.J.3
Centlivre, M.4
Spits, H.5
Weijer, K.6
Blom, B.7
Berkhout, B.8
-
44
-
-
1842614352
-
Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner
-
Van Opijnen T., Jeeninga R.E., Boerlijst M.C., Pollakis G.P., Zetterberg V., Salminen M., Berkhout B. Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner. J. Virol. 2004, 78:3675-3683.
-
(2004)
J. Virol.
, vol.78
, pp. 3675-3683
-
-
Van Opijnen, T.1
Jeeninga, R.E.2
Boerlijst, M.C.3
Pollakis, G.P.4
Zetterberg, V.5
Salminen, M.6
Berkhout, B.7
-
45
-
-
0343907206
-
Protein functions in pre-mRNA splicing
-
Will C.L., Luhrmann R. Protein functions in pre-mRNA splicing. Curr. Opin. Cell Biol. 1997, 9:320-328.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 320-328
-
-
Will, C.L.1
Luhrmann, R.2
-
46
-
-
33748854037
-
Optimization of the Tet-On system for regulated gene expression through viral evolution
-
Zhou X., Vink M., Klaver B., Berkhout B., Das A.T. Optimization of the Tet-On system for regulated gene expression through viral evolution. Gene Ther. 2006, 13:1382-1390.
-
(2006)
Gene Ther.
, vol.13
, pp. 1382-1390
-
-
Zhou, X.1
Vink, M.2
Klaver, B.3
Berkhout, B.4
Das, A.T.5
|