Gene transfer in humans using a conditionally replicating lentiviral vector

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 46, 2006, Pages 17372-17377

  Levine, Bruce L ^a,b   Humeau, Laurent M ^c   Boyer, Jean ^b   MacGregor, Rob Roy ^b   Rebello, Tessio ^c   Lu, Xiaobin ^c,e   Binder, Gwendolyn K ^a,c   Slepushkin, Vladimir ^c   Lemiale, Franck ^c   Mascola, John R ^d   Bushman, Frederic D ^b   Dropulic, Boro ^c,f   June, Carl H ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c VIRxSYS Corporation   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNITED STATES PHARMACOPEIA   (United States)

^f Lentigen Corporation   (United States)

Author keywords

Clinical trials; Gene therapy; HIV; Immunotherapy

Indexed keywords

GENE PRODUCT; UNCLASSIFIED DRUG; VRX 496;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG MECHANISM; DRUG SAFETY; GENE EXPRESSION REGULATION; GENE TRANSFER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOTHERAPY; LENTIVIRUS VECTOR; MALE; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; UNSPECIFIED SIDE EFFECT; VIRUS LOAD; VIRUS REPLICATION;

ADULT; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIV-1; HUMANS; LENTIVIRUS; MIDDLE AGED; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33751251058     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0608138103     Document Type: Article

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