Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells

Nucleic Acids Research

Volumn 41, Issue 16, 2013, Pages 7771-7782

  Qu, Xiying ^a   Wang, Pengfei ^a   Ding, Donglin ^a   Li, Lin ^a   Wang, Haibo ^b   Ma, Li ^b   Zhou, Xin ^a   Liu, Shaohui ^a   Lin, Shiguan ^a   Wang, Xiaohui ^a   Zhang, Gongmin ^a   Liu, Sijie ^a   Liu, Lin ^a   Wang, Jianhua ^b   Zhang, Feng ^a   Lu, Daru ^a   Zhu, Huanzhang ^a  

^a FUDAN UNIVERSITY   (China)

^b INSTITUTE PASTEUR OF SHANGHAI   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GAG PROTEIN; ZINC FINGER NUCLEASE; DEOXYRIBONUCLEASE; VIRUS DNA; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ANTIGEN DETECTION; ARTICLE; CD4+ T LYMPHOCYTE; CELL SPECIFICITY; CONTROLLED STUDY; DNA SEQUENCE; DNA STRAND BREAKAGE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXCISION; FLOW CYTOMETRY; GENE DELETION; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VITRO STUDY; LONG TERMINAL REPEAT; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; T LYMPHOCYTE; VIRUS LATENCY; VIRUS PARTICLE; CELL CULTURE; GENETICS; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; PROVIRUS; VIROLOGY; VIRUS DNA CELL DNA INTERACTION;

CELLS, CULTURED; DNA, VIRAL; ENDODEOXYRIBONUCLEASES; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; JURKAT CELLS; PROVIRUSES; SEQUENCE DELETION; T-LYMPHOCYTES; VIRUS INTEGRATION; VIRUS LATENCY; ZINC FINGERS;

EID: 84885008722     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt571     Document Type: Article

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