Efficacy and mode of action of hammerhead and hairpin ribozymes against various HIV-1 target sites

Molecular Therapy

Volumn 10, Issue 1, 2004, Pages 172-180

  Hotchkiss, Graham ^a,b   Maijgren Steffensson, Catharina ^a   Ährlund Richter, Lars ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Antiviral efficacy; Hairpin; Hammerhead; Ribozyme

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; HAIRPIN RIBOZYME; HAMMERHEAD RIBOZYME; NEF PROTEIN; POL PROTEIN; PROTEIN SUBUNIT; RIBOZYME; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS RNA;

5' UNTRANSLATED REGION; ANTIVIRAL ACTIVITY; ARTICLE; CELL FREE SYSTEM; CELL POPULATION; CELL VIABILITY; CONTROLLED STUDY; DNA INTEGRATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME KINETICS; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INHIBITION KINETICS; LONG TERMINAL REPEAT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROVIRUS; PROVOCATION TEST; REVERSE TRANSCRIPTION; VIRUS REPLICATION;

5' UNTRANSLATED REGIONS; BASE SEQUENCE; CELL LINE; DNA; HIV INFECTIONS; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; PROVIRUSES; RNA, CATALYTIC; RNA, VIRAL; VIRUS INTEGRATION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 3042818032     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.04.015     Document Type: Article

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