-
1
-
-
33646736068
-
A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs
-
O ter Brake B Berkhout A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs J RNAi Gene Silencing 1 2005 56 65
-
(2005)
J RNAi Gene Silencing
, vol.1
, pp. 56-65
-
-
ter Brake, O1
Berkhout, B2
-
2
-
-
33646745522
-
The interplay between virus infection and the cellular RNA interference machinery
-
B Berkhout J Haasnoot The interplay between virus infection and the cellular RNA interference machinery FEBS Lett 580 2006 2896 2902
-
(2006)
FEBS Lett
, vol.580
, pp. 2896-2902
-
-
Berkhout, B1
Haasnoot, J2
-
3
-
-
13444262170
-
Inhibition of respiratory viruses by nasally administered siRNA
-
V Bitko A Musiyenko O Shulyayeva S Barik Inhibition of respiratory viruses by nasally administered siRNA Nat Med 11 2005 50 55
-
(2005)
Nat Med
, vol.11
, pp. 50-55
-
-
Bitko, V1
Musiyenko, A2
Shulyayeva, O3
Barik, S4
-
4
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
TR Brummelkamp R Bernards R Agami A system for stable expression of short interfering RNAs in mammalian cells Science 296 2002 550 553
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, TR1
Bernards, R2
Agami, R3
-
5
-
-
33751193683
-
Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages
-
T Yamamoto H Miyoshi N Yamamoto N Yamamoto J Inoue Y Tsunetsugu-Yokota Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages Blood 108 2006 3305 3312
-
(2006)
Blood
, vol.108
, pp. 3305-3312
-
-
Yamamoto, T1
Miyoshi, H2
Yamamoto, N3
Yamamoto, N4
Inoue, J5
Tsunetsugu-Yokota, Y6
-
6
-
-
10744228940
-
Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs
-
MJ Li G Bauer A Michienzi JK Yee NS Lee J Kim Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs Mol Ther 8 2003 196 206
-
(2003)
Mol Ther
, vol.8
, pp. 196-206
-
-
Li, MJ1
Bauer, G2
Michienzi, A3
Yee, JK4
Lee, NS5
Kim, J6
-
7
-
-
0142124143
-
Human immunodeficiency virus type 1 escape from RNA interference
-
D Boden O Pusch F Lee L Tucker B Ramratnam Human immunodeficiency virus type 1 escape from RNA interference J Virol 77 2003 11531 11535
-
(2003)
J Virol
, vol.77
, pp. 11531-11535
-
-
Boden, D1
Pusch, O2
Lee, F3
Tucker, L4
Ramratnam, B5
-
8
-
-
32444432596
-
Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein
-
HJ Unwalla HT Li I Bahner MJ Li D Kohn JJ Rossi Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein J Virol 80 2006 1863 1873
-
(2006)
J Virol
, vol.80
, pp. 1863-1873
-
-
Unwalla, HJ1
Li, HT2
Bahner, I3
Li, MJ4
Kohn, D5
Rossi, JJ6
-
9
-
-
33751001588
-
Silencing of HIV-1 with RNA interference: a multiple shRNA approach
-
O ter Brake P Konstantinova M Ceylan B Berkhout Silencing of HIV-1 with RNA interference: a multiple shRNA approach Mol Ther 14 2006 883 892
-
(2006)
Mol Ther
, vol.14
, pp. 883-892
-
-
ter Brake, O1
Konstantinova, P2
Ceylan, M3
Berkhout, B4
-
10
-
-
13844320402
-
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
-
EM Westerhout M Ooms M Vink AT Das B Berkhout HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome Nucleic Acids Res 33 2005 796 804
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 796-804
-
-
Westerhout, EM1
Ooms, M2
Vink, M3
Das, AT4
Berkhout, B5
-
12
-
-
7944228148
-
RNA interference as an antiviral approach: targeting HIV-1
-
B Berkhout RNA interference as an antiviral approach: targeting HIV-1 Curr Opin Mol Ther 6 2004 141 145
-
(2004)
Curr Opin Mol Ther
, vol.6
, pp. 141-145
-
-
Berkhout, B1
-
13
-
-
13744250051
-
Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape
-
JN Leonard DV Schaffer Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape J Virol 79 2005 1645 1654
-
(2005)
J Virol
, vol.79
, pp. 1645-1654
-
-
Leonard, JN1
Schaffer, DV2
-
14
-
-
33745699508
-
Antiretroviral treatment of HIV infected adults
-
SG Deeks Antiretroviral treatment of HIV infected adults BMJ 332 2006 1489
-
(2006)
BMJ
, vol.332
, pp. 1489
-
-
Deeks, SG1
-
15
-
-
33750562166
-
The lifetime cost of current human immunodeficiency virus care in the United States
-
BR Schackman KA Gebo RP Walensky E Losina T Muccio PE Sax The lifetime cost of current human immunodeficiency virus care in the United States Med Care 44 2006 990 997
-
(2006)
Med Care
, vol.44
, pp. 990-997
-
-
Schackman, BR1
Gebo, KA2
Walensky, RP3
Losina, E4
Muccio, T5
Sax, PE6
-
16
-
-
34247278567
-
Combinatorial RNAi: a winning strategy for the race against evolving targets?
-
D Grimm MA Kay Combinatorial RNAi: a winning strategy for the race against evolving targets? Mol Ther 15 2007 878 888
-
(2007)
Mol Ther
, vol.15
, pp. 878-888
-
-
Grimm, D1
Kay, MA2
-
17
-
-
34848814237
-
Design of extended short hairpin RNAs for HIV-1 inhibition
-
Y Liu J Haasnoot B Berkhout Design of extended short hairpin RNAs for HIV-1 inhibition Nucleic Acids Res 35 2007 5683 5693
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5683-5693
-
-
Liu, Y1
Haasnoot, J2
Berkhout, B3
-
19
-
-
33748081146
-
Simultaneous targeting of HCV replication and viral binding with a single lentiviral vector containing multiple RNA interference expression cassettes
-
SD Henry WP van der HJ Metselaar HW Tilanus BJ Scholte LJ van der Laan Simultaneous targeting of HCV replication and viral binding with a single lentiviral vector containing multiple RNA interference expression cassettes Mol Ther 14 2006 485 493
-
(2006)
Mol Ther
, vol.14
, pp. 485-493
-
-
Henry, SD1
van der, WP2
Metselaar, HJ3
Tilanus, HW4
Scholte, BJ5
van der Laan, LJ6
-
20
-
-
20244378556
-
RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model
-
SQ Harper PD Staber X He SL Eliason IH Martins Q Mao RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model Proc Natl Acad Sci USA 102 2005 5820 5825
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5820-5825
-
-
Harper, SQ1
Staber, PD2
He, X3
Eliason, SL4
Martins, IH5
Mao, Q6
-
21
-
-
20244381261
-
Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model
-
GS Ralph PA Radcliffe DM Day JM Carthy MA Leroux DC Lee Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model Nat Med 11 2005 429 433
-
(2005)
Nat Med
, vol.11
, pp. 429-433
-
-
Ralph, GS1
Radcliffe, PA2
Day, DM3
Carthy, JM4
Leroux, MA5
Lee, DC6
-
22
-
-
10244237695
-
Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2–/– gammac–/– mice: functional inactivation of p53 in developing T cells
-
–/– mice: functional inactivation of p53 in developing T cells Blood 104 2004 3886 3893
-
(2004)
Blood
, vol.104
, pp. 3886-3893
-
-
Gimeno, R1
Weijer, K2
Voordouw, A3
Uittenbogaart, CH4
Legrand, N5
Alves, NL6
-
23
-
-
0347517725
-
Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain
-
C van den Haute K Eggermont B Nuttin Z Debyser V Baekelandt Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain Hum Gene Ther 14 2003 1799 1807
-
(2003)
Hum Gene Ther
, vol.14
, pp. 1799-1807
-
-
van den Haute, C1
Eggermont, K2
Nuttin, B3
Debyser, Z4
Baekelandt, V5
-
24
-
-
34548574859
-
Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions
-
O ter Brake B Berkhout Lentiviral vectors that carry anti-HIV shRNAs: problems and solutions J Gene Med 9 2007 743 750
-
(2007)
J Gene Med
, vol.9
, pp. 743-750
-
-
ter Brake, O1
Berkhout, B2
-
25
-
-
27744605569
-
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy
-
MJ Li J Kim S Li J Zaia JK Yee J Anderson Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy Mol Ther 12 2005 900 909
-
(2005)
Mol Ther
, vol.12
, pp. 900-909
-
-
Li, MJ1
Kim, J2
Li, S3
Zaia, J4
Yee, JK5
Anderson, J6
-
26
-
-
34249336747
-
Safety and efficacy of a lentiviral vector containing three anti-HIV genes—CCR5 ribozyme, tat-rev siRNA, and TAR decoy—in SCID-hu mouse-derived T cells
-
J Anderson MJ Li B Palmer L Remling S Li P Yam Safety and efficacy of a lentiviral vector containing three anti-HIV genes—CCR5 ribozyme, tat-rev siRNA, and TAR decoy—in SCID-hu mouse-derived T cells Mol Ther 15 2007 1182 1188
-
(2007)
Mol Ther
, vol.15
, pp. 1182-1188
-
-
Anderson, J1
Li, MJ2
Palmer, B3
Remling, L4
Li, S5
Yam, P6
-
27
-
-
0035422614
-
Frequency of direct repeat deletion in a human immunodeficiency virus type 1 vector during reverse transcription in human cells
-
W An A Telesnitsky Frequency of direct repeat deletion in a human immunodeficiency virus type 1 vector during reverse transcription in human cells Virology 286 2001 475 482
-
(2001)
Virology
, vol.286
, pp. 475-482
-
-
An, W1
Telesnitsky, A2
-
28
-
-
0035932984
-
In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
-
G Marzio K Verhoef M Vink B Berkhout In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies Proc Natl Acad Sci USA 98 2001 6342 6347
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6342-6347
-
-
Marzio, G1
Verhoef, K2
Vink, M3
Berkhout, B4
-
29
-
-
0036827628
-
Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots
-
J Zhuang AE Jetzt G Sun H Yu G Klarmann Y Ron Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots J Virol 76 2002 11273 11282
-
(2002)
J Virol
, vol.76
, pp. 11273-11282
-
-
Zhuang, J1
Jetzt, AE2
Sun, G3
Yu, H4
Klarmann, G5
Ron, Y6
-
30
-
-
0033977268
-
High rate of recombination throughout the human immunodeficiency virus type 1 genome
-
AE Jetzt H Yu GJ Klarmann Y Ron BD Preston JP Dougherty High rate of recombination throughout the human immunodeficiency virus type 1 genome J Virol 74 2000 1234 1240
-
(2000)
J Virol
, vol.74
, pp. 1234-1240
-
-
Jetzt, AE1
Yu, H2
Klarmann, GJ3
Ron, Y4
Preston, BD5
Dougherty, JP6
-
31
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
JY Yu SL DeRuiter DL Turner RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells Proc Natl Acad Sci USA 99 2002 6047 6052
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6047-6052
-
-
Yu, JY1
DeRuiter, SL2
Turner, DL3
-
32
-
-
5044219937
-
RNA interference by small hairpin RNAs synthesised under control of the human 7S K RNA promoter
-
D Koper-Emde L Herrmann B Sandrock BJ Benecke RNA interference by small hairpin RNAs synthesised under control of the human 7S K RNA promoter Biol Chem 385 2004 791 794
-
(2004)
Biol Chem
, vol.385
, pp. 791-794
-
-
Koper-Emde, D1
Herrmann, L2
Sandrock, B3
Benecke, BJ4
-
33
-
-
3042854926
-
A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells
-
MA Denti A Rosa O Sthandier FG De Angelis I Bozzoni A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells Mol Ther 10 2004 191 199
-
(2004)
Mol Ther
, vol.10
, pp. 191-199
-
-
Denti, MA1
Rosa, A2
Sthandier, O3
De Angelis, FG4
Bozzoni, I5
-
34
-
-
34548548614
-
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
-
D Castanotto K Sakurai R Lingeman H Li L Shively L Aagaard Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC Nucleic Acids Res 35 2007 5154 5164
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5154-5164
-
-
Castanotto, D1
Sakurai, K2
Lingeman, R3
Li, H4
Shively, L5
Aagaard, L6
-
35
-
-
0342699700
-
A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene
-
E Kotsopoulou VN Kim AJ Kingsman SM Kingsman KA Mitrophanous A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene J Virol 74 2000 4839 4852
-
(2000)
J Virol
, vol.74
, pp. 4839-4852
-
-
Kotsopoulou, E1
Kim, VN2
Kingsman, AJ3
Kingsman, SM4
Mitrophanous, KA5
-
36
-
-
0034783643
-
Systematic determination of the packaging limit of lentiviral vectors
-
M Kumar B Keller N Makalou RE Sutton Systematic determination of the packaging limit of lentiviral vectors Hum Gene Ther 12 2001 1893 1905
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1893-1905
-
-
Kumar, M1
Keller, B2
Makalou, N3
Sutton, RE4
-
37
-
-
0026318224
-
Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI
-
K Peden M Emerman L Montagnier Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI Virology 185 1991 661 672
-
(1991)
Virology
, vol.185
, pp. 661-672
-
-
Peden, K1
Emerman, M2
Montagnier, L3
-
39
-
-
33845221484
-
HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector
-
J Anderson R Akkina HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector AIDS Res Ther 2 2005 1
-
(2005)
AIDS Res Ther
, vol.2
, pp. 1
-
-
Anderson, J1
Akkina, R2
-
41
-
-
4544380838
-
Poly(U) and polyadenylation termination signals are interchangeable for terminating the expression of shRNA from a pol II promoter
-
J Song S Pang Y Lu R Chiu Poly(U) and polyadenylation termination signals are interchangeable for terminating the expression of shRNA from a pol II promoter Biochem Biophys Res Commun 323 2004 573 578
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 573-578
-
-
Song, J1
Pang, S2
Lu, Y3
Chiu, R4
-
42
-
-
33748978456
-
The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference
-
EM Westerhout O ter Brake B Berkhout The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference Retrovirology 3 2006 57
-
(2006)
Retrovirology
, vol.3
, pp. 57
-
-
Westerhout, EM1
ter Brake, O2
Berkhout, B3
-
43
-
-
0036891843
-
RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication
-
RM Surabhi RB Gaynor RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication J Virol 76 2002 12963 12973
-
(2002)
J Virol
, vol.76
, pp. 12963-12973
-
-
Surabhi, RM1
Gaynor, RB2
-
44
-
-
32044454701
-
Experimental models to study development and function of the human immune system in vivo
-
N Legrand K Weijer H Spits Experimental models to study development and function of the human immune system in vivo J Immunol 176 2006 2053 2058
-
(2006)
J Immunol
, vol.176
, pp. 2053-2058
-
-
Legrand, N1
Weijer, K2
Spits, H3
-
46
-
-
33846104485
-
Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses
-
S Watanabe K Terashima S Ohta S Horibata M Yajima Y Shiozawa Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses Blood 109 2007 212 218
-
(2007)
Blood
, vol.109
, pp. 212-218
-
-
Watanabe, S1
Terashima, K2
Ohta, S3
Horibata, S4
Yajima, M5
Shiozawa, Y6
-
48
-
-
15944391296
-
Gene therapy progress and prospects: novel gene therapy approaches for AIDS
-
R Wolkowicz GP Nolan Gene therapy progress and prospects: novel gene therapy approaches for AIDS Gene Ther 12 2005 467 476
-
(2005)
Gene Ther
, vol.12
, pp. 467-476
-
-
Wolkowicz, R1
Nolan, GP2
-
50
-
-
0036116344
-
Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes
-
J Seppen M Rijnberg MP Cooreman RP Oude Elferink Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes J Hepatol 36 2002 459 465
-
(2002)
J Hepatol
, vol.36
, pp. 459-465
-
-
Seppen, J1
Rijnberg, M2
Cooreman, MP3
Oude Elferink, RP4
|