DNA repair and redox activities and inhibitors of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): A comparative analysis and their scope and limitations toward anticancer drug development

Journal of Medicinal Chemistry

Volumn 57, Issue 24, 2014, Pages 10241-10256

  Kaur, Gagandeep ^a   Cholia, Ravi P ^a   Mantha, Anil K ^a   Kumar, Raj ^a  

^a CENTRAL UNIVERSITY OF PUNJAB   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CELL NUCLEUS DNA; DEOXYRIBONUCLEASE I; HYDROGEN PEROXIDE; MULTIFUNCTIONAL ENZYME; REDOX EFFECTOR FACTOR 1; STAT3 PROTEIN; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE;

CANCER GROWTH; DNA DAMAGE; DNA REPAIR; ENVIRONMENTAL FACTOR; MACROPHAGE; MITOCHONDRION; MOTONEURON; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; REVIEW; RNA BINDING; ANTAGONISTS AND INHIBITORS; COMPARATIVE STUDY; DRUG DESIGN; DRUG EFFECTS; HUMAN; NEOPLASMS; OXIDATION REDUCTION REACTION;

ANTINEOPLASTIC AGENTS; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DRUG DESIGN; HUMANS; NEOPLASMS; OXIDATION-REDUCTION;

EID: 84920120388     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500865u     Document Type: Review

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