Unusual Role of a Cysteine Residue in Substrate Binding and Activity of Human AP-Endonuclease 1

Journal of Molecular Biology

Volumn 379, Issue 1, 2008, Pages 28-37

  Mantha, Anil K ^a   Oezguen, Numan ^a   Bhakat, Kishor K ^a   Izumi, Tadahide ^b   Braun, Werner ^a   Mitra, Sankar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AP endonuclease; DNA base excision repair; DNA binding; human APE1; Ref 1

Indexed keywords

CYSTEINE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; HISTIDINE; MAGNESIUM; SERINE;

APYRIMIDINIC SITE; ARTICLE; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTALLOGRAPHY; DNA BINDING; DNA CLEAVAGE; ENZYME ACTIVITY; ENZYME KINETICS; FLAME PHOTOMETRY; FLUORESCENCE SPECTROSCOPY; GENE MUTATION; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIMULATION;

MAMMALIA;

EID: 42749086668     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.03.052     Document Type: Article

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