Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease

Journal of Molecular Biology

Volumn 287, Issue 1, 1999, Pages 47-57

  Izumi, Tadahide ^a,b   Malecki, Jedrzej ^b   Chaudhry, M Ahmad ^c   Weinfeld, Michael ^c   Hill, Jeff H ^a   Lee, J Ching ^b   Mitra, Sankar ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c CROSS CANCER INSTITUTE   (Canada)

Author keywords

3'phosphoesterase; AP endonuclease; DNA repair; Missense mutation; Site directed mutagenesis

Indexed keywords

ASPARTIC ACID; COMPLEMENTARY DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; GLUTAMIC ACID; MAGNESIUM ION; MUTANT PROTEIN; PHOSPHATASE; TRYPTOPHAN;

ARTICLE; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; HUMAN; MICHAELIS CONSTANT; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; SUPPRESSOR GENE;

ALOCASIA MACRORRHIZOS; ESCHERICHIA COLI; FELIS CATUS;

EID: 0033583089     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.2573     Document Type: Article

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