-
2
-
-
0030936568
-
Ap-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
-
DOI 10.1073/pnas.94.8.3633
-
Hirota K, Matsui M, Iwata S, Nishiyama A, Mori K, Yodoi J 1997 AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci USA 94:3633-3638 (Pubitemid 27180424)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.8
, pp. 3633-3638
-
-
Hirota, K.1
Matsui, M.2
Iwata, S.3
Nishiyama, A.4
Mori, K.5
Yodoi, J.6
-
3
-
-
0030900605
-
Identification of redox/repair protein Ref-1 as a potent activator of p53
-
Jayaraman L, Murthy KG, Zhu C, Curran T, Xanthoudakis S, Prives C 1997 Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev 11:558-570 (Pubitemid 27133376)
-
(1997)
Genes and Development
, vol.11
, Issue.5
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.G.K.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
5
-
-
32244435724
-
Is base excision repair a tumor suppressor mechanism?
-
Sweasy JB, Lang T, DiMaio D 2006 Is base excision repair a tumor suppressor mechanism? Cell Cycle 5:250-259
-
(2006)
Cell Cycle
, vol.5
, pp. 250-259
-
-
Sweasy, J.B.1
Lang, T.2
DiMaio, D.3
-
6
-
-
0023808861
-
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer
-
DOI 10.1016/0092-8674(88)90017-7
-
Kumar V, Chambon P 1988 The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell 55:145-156 (Pubitemid 18243642)
-
(1988)
Cell
, vol.55
, Issue.1
, pp. 145-156
-
-
Kumar, V.1
Chambon, P.2
-
7
-
-
0024296177
-
A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor
-
Klein-Hitpass L, Ryffel GU, Heitlinger E, Cato ACB 1988 A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor. Nucleic Acids Res 16:647-663
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 647-663
-
-
Klein-Hitpass, L.1
Ryffel, G.U.2
Heitlinger, E.3
Cato, A.C.B.4
-
8
-
-
0033305438
-
Estrogen receptor null mice: What have we learned and where will they lead us?
-
Couse JF, Korach KS 1999 Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 20:358-417
-
(1999)
Endocr Rev
, vol.20
, pp. 358-417
-
-
Couse, J.F.1
Korach, K.S.2
-
9
-
-
0028625491
-
Insights from the study of animals lacking functional estrogen receptor
-
Korach KS 1994 Insights from the study of animals lacking functional estrogen receptor. Science 266:1524-1527
-
(1994)
Science
, vol.266
, pp. 1524-1527
-
-
Korach, K.S.1
-
10
-
-
0031983511
-
Mechanisms of cardioprotection by estrogens
-
Subbiah MTR 1998 Mechanisms of cardioprotection by estrogens. Proc Soc Exp Biol Med 217:23-29
-
(1998)
Proc Soc Exp Biol Med
, vol.217
, pp. 23-29
-
-
Subbiah, M.T.R.1
-
11
-
-
0029917449
-
Mechanisms of estrogen action during neural development: Mediation by interactions with the neurotophins and their receptors?
-
Toran-Allerand CD 1996 Mechanisms of estrogen action during neural development: mediation by interactions with the neurotophins and their receptors? J Steroid Biochem 56:169-178
-
(1996)
J Steroid Biochem
, vol.56
, pp. 169-178
-
-
Toran-Allerand, C.D.1
-
12
-
-
0141785350
-
Profiling of estrogen up- And down-regulated gene expression in human breast cancer cells: Insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype
-
DOI 10.1210/en.2003-0567
-
Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR, Katzenellenbogen BS 2003 Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144:4562-4574 (Pubitemid 37204856)
-
(2003)
Endocrinology
, vol.144
, Issue.10
, pp. 4562-4574
-
-
Frasor, J.1
Danes, J.M.2
Komm, B.3
Chang, K.C.N.4
Richard Lyttle, C.5
Katzenellenbogen, B.S.6
-
13
-
-
3042681155
-
Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) α or ERβ in human osteosarcoma cells: Distinct and common target genes for these receptors
-
DOI 10.1210/en.2003-1682
-
Stossi F, Barnett DH, Frasor J, Komm B, Lyttle CR, Katzenellenbogen BS 2004 Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) α or ERβ in human osteosarcoma cells: distinct and common target genes for these receptors. Endocrinology 145:3473-3486 (Pubitemid 38830020)
-
(2004)
Endocrinology
, vol.145
, Issue.7
, pp. 3473-3486
-
-
Stossi, F.1
Barnett, D.H.2
Frasor, J.3
Komm, B.4
Lyttle, C.R.5
Katzenellenbogen, B.S.6
-
14
-
-
0021771164
-
Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7
-
Jakowlew SB, Breathnach R, Jeltsch JM, Masiakowski P, Chambon P 1984 Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7. Nucleic Acids Res 12:2861-2878
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 2861-2878
-
-
Jakowlew, S.B.1
Breathnach, R.2
Jeltsch, J.M.3
Masiakowski, P.4
Chambon, P.5
-
15
-
-
0023583135
-
Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2
-
Rio MC, Bellocq JP, Gairard B, Rasmussen UB, Krust A, Koehl C, Calderoli H, Schiff V, Renaud R, Chambon P 1987 Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2. Proc Natl Acad Sci USA 84:9243-9247 (Pubitemid 18055341)
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.24
, pp. 9243-9247
-
-
Rio, M.C.1
Bellocq, J.P.2
Gairard, B.3
Rasmussen, U.B.4
Krust, A.5
Koehl, C.6
Calderoli, H.7
Schiff, V.8
Renaud, R.9
Chambon, P.10
-
16
-
-
0034668704
-
Regulation of the estrogen-responsive pS2 gene in MCF-7 human breast cancer cells
-
DOI 10.1016/S0960-0760(00)00119-9, PII S0960076000001199
-
Kim J, Petz LN, Ziegler YS, Wood JR, Potthoff SJ, Nardulli AM 2000 Regulation of the estrogen-responsive pS2 gene in MCF-7 human breast cancer cells. J Steroid Biochem 74:157-168 (Pubitemid 32121651)
-
(2000)
Journal of Steroid Biochemistry and Molecular Biology
, vol.74
, Issue.4
, pp. 157-168
-
-
Kim, J.1
Petz, L.N.2
Ziegler, Y.S.3
Wood, J.R.4
Potthoff, S.J.5
Nardulli, A.M.6
-
17
-
-
0034000089
-
The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding
-
Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP 2000 The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Mol Cell Biol 20:3102-3115
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3102-3115
-
-
Giangrande, P.H.1
Kimbrel, E.A.2
Edwards, D.P.3
McDonnell, D.P.4
-
18
-
-
0025239785
-
Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms a and B
-
Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, Chambon P 1990 Two distinct estrogen-regulated promoters generate transcripts encoding two functionally different human progesterone receptor forms A and B. EMBO J 9:1603-1614 (Pubitemid 20137018)
-
(1990)
EMBO Journal
, vol.9
, Issue.5
, pp. 1603-1614
-
-
Kastner, P.1
Krust, A.2
Turcotte, B.3
Stropp, U.4
Tora, L.5
Gronemeyer, H.6
Chambon, P.7
-
19
-
-
0030838711
-
Functional modulation of estrogen receptor by redox state with reference to thioredoxin as a mediator
-
DOI 10.1093/nar/25.20.4035
-
Hayashi S, Hajiro-Nakanishi K, Makino Y, Eguchi H, Yodoi J, Tanaka H 1997 Functional modulation of estrogen receptor by redox state with reference to thioredoxin as a mediator. Nucleic Acids Res 25:4035-4040 (Pubitemid 27443331)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.20
, pp. 4035-4040
-
-
Hayashi, S.-I.1
Hajiro-Nakanishi, K.2
Makino, Y.3
Eguchi, H.4
Yodoi, J.5
Tanaka, H.6
-
20
-
-
33747838884
-
Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor α structure and function
-
Schultz-Norton JR, McDonald WH, Yates JR, Nardulli AM 2006 Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor α structure and function. Mol Endocrinol 20:1982-1995
-
(2006)
Mol Endocrinol
, vol.20
, pp. 1982-1995
-
-
Schultz-Norton, J.R.1
McDonald, W.H.2
Yates, J.R.3
Nardulli, A.M.4
-
21
-
-
74949112586
-
Isolation of proteins associated with the DNA-bound estrogen receptor α
-
Park Sarge O-K, Curry T, eds. Totowa, NJ: Humana Press
-
Schultz-Norton JR, Ziegler YS, Likhite VS, Nardulli AM 2009 Isolation of proteins associated with the DNA-bound estrogen receptor α. In: Park Sarge O-K, Curry T, eds. Molecular endocrinology: a comprehensive guide to current methodologies. Totowa, NJ: Humana Press
-
(2009)
Molecular Endocrinology: A Comprehensive Guide to Current Methodologies
-
-
Schultz-Norton, J.R.1
Ziegler, Y.S.2
Likhite, V.S.3
Nardulli, A.M.4
-
22
-
-
56649089874
-
Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor α
-
Schultz-Norton JR, Ziegler YS, Likhite VS, Yates JR, Nardulli AM 2008 Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor α. BMC Mol Biol 9:97
-
(2008)
BMC Mol Biol
, vol.9
, pp. 97
-
-
Schultz-Norton, J.R.1
Ziegler, Y.S.2
Likhite, V.S.3
Yates, J.R.4
Nardulli, A.M.5
-
23
-
-
8344256470
-
A novel estrogen receptor α-associated protein alters receptor-deoxyribonucleic acid interactions and represses receptor-mediated transcription
-
DOI 10.1210/me.2003-0195
-
Loven MA, Davis RE, Curtis CD, Muster N, Yates JR, NardulliAM 2004 A novel estrogen receptor α-associated protein alters receptor- deoxyribonucleic acid interactions and represses receptor-mediated transcription. Mol Endocrinol 18:2649-2659 (Pubitemid 39482055)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.11
, pp. 2649-2659
-
-
Loven, M.A.1
Davis, R.E.2
Curtis, C.D.3
Muster, N.4
Yates, J.R.5
Nardulli, A.M.6
-
24
-
-
12244256087
-
A novel estrogen receptor α-associated protein, template-activating factor Iβ, inhibits acetylation and transactivation
-
DOI 10.1210/me.2002-0280
-
Loven MA, Muster N, Yates JR, Nardulli AM 2003 A novel estrogen receptor α associated protein, template activating factor I β, inhibits acetylation and transactivation. Mol Endocrinol 17:67-78 (Pubitemid 36138724)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.1
, pp. 67-78
-
-
Loven, M.A.1
Muster, N.2
Yates, J.R.3
Nardulli, A.M.4
-
25
-
-
34347213797
-
The deoxyribonucleic acid repair protein flap endonuclease-1 modulates estrogen-responsive gene expression
-
Schultz-Norton JR, Walt KA, Ziegler YS, McLeod IX, Yates JR, Raetzman LT, Nardulli AM 2007 The deoxyribonucleic acid repair protein flap endonuclease-1 modulates estrogen-responsive gene expression. Mol Endocrinol 21:1569-1580
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1569-1580
-
-
Schultz-Norton, J.R.1
Walt, K.A.2
Ziegler, Y.S.3
McLeod, I.X.4
Yates, J.R.5
Raetzman, L.T.6
Nardulli, A.M.7
-
26
-
-
34548548619
-
Interaction of estrogen receptor α with proliferating cell nuclear antigen
-
DOI 10.1093/nar/gkm533
-
Schultz-Norton JR, Gabisi VA, Ziegler YS, McLeod IX, Yates JR, Nardulli AM 2007 Interaction of estrogen receptor α with proliferating cell nuclear antigen. Nucleic Acids Res 35:5028-5038 (Pubitemid 47394188)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.15
, pp. 5028-5038
-
-
Schultz-Norton, J.R.1
Gabisi, V.A.2
Ziegler, Y.S.3
McLeod, I.X.4
Yates, J.R.5
Nardulli, A.M.6
-
27
-
-
35748970765
-
Rho GDP dissociation inhibitor α interacts with estrogen receptor α and influences estrogen responsiveness
-
DOI 10.1677/JME-07-0055
-
El Marzouk S, Schultz-Norton JR, Likhite VS, McLeod IX, Yates JR, Nardulli AM 2007 Rho GDP dissociation inhibitor α interacts with estrogen receptor α and influences estrogen responsiveness. J Mol Endocrinol 39:249-259 (Pubitemid 350047646)
-
(2007)
Journal of Molecular Endocrinology
, vol.39
, Issue.3-4
, pp. 249-259
-
-
El Marzouk, S.1
Schultz-Norton, J.R.2
Likhite, V.S.3
McLeod, I.X.4
Yates, J.R.5
Nardulli, A.M.6
-
28
-
-
43049127455
-
Effects of Cu/Zn superoxide dismutase on estrogen responsiveness and oxidative stress in human breast cancer cells
-
Rao AK, Ziegler YS, McLeod IX, Yates JR, Nardulli AM 2008 Effects of Cu/Zn superoxide dismutase on estrogen responsiveness and oxidative stress in human breast cancer cells. Mol Endocrinol 22:1113-1124
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1113-1124
-
-
Rao, A.K.1
Ziegler, Y.S.2
McLeod, I.X.3
Yates, J.R.4
Nardulli, A.M.5
-
29
-
-
48349143472
-
The role of retinoblastoma associated proteins 46 and 48 in estrogen receptor α mediated gene expression
-
Creekmore AL, Walt KA, Schultz-Norton JR, Ziegler YS, McLeod IX, Yates JR, Nardulli AM 2008 The role of retinoblastoma associated proteins 46 and 48 in estrogen receptor α mediated gene expression. Mol Cell Endocrinol 291:79-86
-
(2008)
Mol Cell Endocrinol
, vol.291
, pp. 79-86
-
-
Creekmore, A.L.1
Walt, K.A.2
Schultz-Norton, J.R.3
Ziegler, Y.S.4
McLeod, I.X.5
Yates, J.R.6
Nardulli, A.M.7
-
30
-
-
0030950531
-
Af-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors
-
Henttu PM, Kalkhoven E, Parker MG 1997 AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors. Mol Cell Biol 17:1832-1839 (Pubitemid 27133268)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.4
, pp. 1832-1839
-
-
Henttu, P.M.A.1
Kalkhoven, E.2
Parker, M.G.3
-
31
-
-
0031742084
-
Differential expression of estrogen receptor-β (ERβ) in human pituitary tumors: Functional interactions with ERα and a tumor-specific splice variant
-
DOI 10.1210/jc.83.9.3308
-
Chaidarun SS, Swearingen B, Alexander JM 1998 Differential expression of estrogen receptor-β (ER β) in human pituitary tumors: functional interactions with ER α and a tumor-specific splice variant. J Clin Endocrinol Metab 83:3308-3315 (Pubitemid 28500977)
-
(1998)
Journal of Clinical Endocrinology and Metabolism
, vol.83
, Issue.9
, pp. 3308-3315
-
-
Chaidarun, S.S.1
Swearingen, B.2
Alexander, J.M.3
-
32
-
-
0034969440
-
Allosteric modulation of estrogen receptor conformation by different estrogen response elements
-
DOI 10.1210/me.15.7.1114
-
Wood JR, Likhite VS, Loven MA, Nardulli AM 2001 Allosteric modulation of estrogen receptor conformation by different estrogen response elements. Mol Endocrinol 15:1114-1126 (Pubitemid 32614066)
-
(2001)
Molecular Endocrinology
, vol.15
, Issue.7
, pp. 1114-1126
-
-
Wood, J.R.1
Likhite, V.S.2
Loven, M.A.3
Nardulli, A.M.4
-
33
-
-
0023926059
-
Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: Analysis of estrogen's effect on progesterone receptor synthesis and degradation
-
Nardulli AM, Greene GL, O'Malley BW, Katzenellenbogen BS 1988 Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: analysis of estrogen's effect on progesterone receptor synthesis and degradation. Endocrinology 122:935-944
-
(1988)
Endocrinology
, vol.122
, pp. 935-944
-
-
Nardulli, A.M.1
Greene, G.L.2
O'Malley, B.W.3
Katzenellenbogen, B.S.4
-
34
-
-
33847377224
-
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain
-
DOI 10.1182/blood-2006-08-044172
-
Zou GM, Luo MH, Reed A, Kelley MR, Yoder MC 2007 Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. Blood 109:1917-1922 (Pubitemid 46348187)
-
(2007)
Blood
, vol.109
, Issue.5
, pp. 1917-1922
-
-
Zou, G.-M.1
Luo, M.-H.2
Reed, A.3
Kelley, M.R.4
Yoder, M.C.5
-
35
-
-
27844501168
-
Molecular and biological roles of Ape1 protein in mammalian base excision repair
-
DOI 10.1016/j.dnarep.2005.09.004, PII S1568786405002557
-
Demple B, Sung JS 2005 Molecular and biological roles of Ape1 protein in mammalian base excision repair. DNA Repair 4:1442-1449 (Pubitemid 41653305)
-
(2005)
DNA Repair
, vol.4
, Issue.12
, pp. 1442-1449
-
-
Demple, B.1
Sung, J.-S.2
-
36
-
-
34548276529
-
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
-
Fishel ML, Kelley MR 2007 The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target. Mol Aspects Med 28:375-395
-
(2007)
Mol Aspects Med
, vol.28
, pp. 375-395
-
-
Fishel, M.L.1
Kelley, M.R.2
-
37
-
-
37549033163
-
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
-
Fishel ML, He Y, Reed AM, Chin-Sinex H, Hutchins GD, Mendonca MS, Kelley MR 2008 Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth. DNA Repair 7:177-186
-
(2008)
DNA Repair
, vol.7
, pp. 177-186
-
-
Fishel, M.L.1
He, Y.2
Reed, A.M.3
Chin-Sinex, H.4
Hutchins, G.D.5
Mendonca, M.S.6
Kelley, M.R.7
-
38
-
-
0025331418
-
Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity
-
Lundström J, Holmgren A 1990 Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. J Biol Chem 265:9114-9120 (Pubitemid 20190355)
-
(1990)
Journal of Biological Chemistry
, vol.265
, Issue.16
, pp. 9114-9120
-
-
Lundstrom, J.1
Holmgren, A.2
-
39
-
-
0026583944
-
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
-
Xanthoudakis S, CurranT1992 Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J 11:653-665
-
(1992)
EMBO J
, vol.11
, pp. 653-665
-
-
Xanthoudakis, S.1
Curran, T.2
-
40
-
-
0026069790
-
Processing in vitro of an abasic site reacted with methoxyamine: A new assay for the detection of abasic sites formed in vivo
-
Rosa S, Fortini P, Karran P, Bignami M, Dogliotti E 1991 Processing in vitro of an abasic site reacted with methoxyamine: a new assay for the detection of abasic sites formed in vivo. Nucleic Acids Res 19:5569-5574 (Pubitemid 21912956)
-
(1991)
Nucleic Acids Research
, vol.19
, Issue.20
, pp. 5569-5574
-
-
Rosa, S.1
Fortini, P.2
Karran, P.3
Bignami, M.4
Dogliotti, E.5
-
41
-
-
4043143034
-
Therapeutic impact of methoxyamine: Blocking repair of abasic sites in the base excision repair pathway
-
Liu L, Gerson SL 2004 Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway. Curr Opin Investig Drugs 5:623-627
-
(2004)
Curr Opin Investig Drugs
, vol.5
, pp. 623-627
-
-
Liu, L.1
Gerson, S.L.2
-
42
-
-
0031964618
-
Nuclear targeted suppression of NF-κB activity by the novel quinone derivative E3330
-
Hiramoto M, Shimizu N, Sugimoto K, Tang J, Kawakami Y, Ito M, Aizawa S, Tanaka H, Makino I, Handa H 1998 Nuclear targeted suppression of NF-κ B activity by the novel quinone derivative E3330. J Immunol 160:810-819 (Pubitemid 28049322)
-
(1998)
Journal of Immunology
, vol.160
, Issue.2
, pp. 810-819
-
-
Hiramoto, M.1
Shimizu, N.2
Sugimoto, K.3
Tang, J.4
Kawakami, Y.5
Ito, M.6
Aizawa, S.7
Tanaka, H.8
Makino, I.9
Handa, H.10
-
43
-
-
0033877274
-
High-performance affinity beads for identifying drug receptors
-
DOI 10.1038/78496
-
Shimizu N, Sugimoto K, Tang J, Nishi T, Sato I, Hiramoto M, Aizawa S, Hatakeyama M, Ohba R, Hatori H, Yoshikawa T, Suzuki F, Oomori A, Tanaka H, Kawaguchi H, Watanabe H, Handa H 2000 High-performance affinity beads for identifying drug receptors. Nat Biotechnol 18:877-881 (Pubitemid 30640915)
-
(2000)
Nature Biotechnology
, vol.18
, Issue.8
, pp. 877-881
-
-
Shimizu, N.1
Sugimoto, K.2
Tang, J.3
Nishi, T.4
Sato, I.5
Hiramoto, M.6
Aizawa, S.7
Hatakeyama, M.8
Ohba, R.9
Hatori, H.10
Yoshikawa, T.11
Suzuki, F.12
Oomori, A.13
Tanaka, H.14
Kawaguchi, H.15
Watanabe, H.16
Handa, H.17
-
44
-
-
51049091691
-
Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration
-
Zou GM, Maitra A 2008 Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration. Mol Cancer Ther 7:2012-2021
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2012-2021
-
-
Zou, G.M.1
Maitra, A.2
-
45
-
-
51349134457
-
Role of the multifunctional DNA repair and redox signaling protein Ape1/ Ref-1 in cancer and endothelial cells: Small-molecule Inhibition of the redox function of Ape1
-
Luo M, Delaplane S, Jiang A, Reed A, He Y, Fishel M, Nyland 2nd RL, Borch RF, Qiao X, Georgiadis MM, Kelley MR 2008 Role of the multifunctional DNA repair and redox signaling protein Ape1/ Ref-1 in cancer and endothelial cells: small-molecule Inhibition of the redox function of Ape1. Antioxid Redox Signal 10:1853-1867
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1853-1867
-
-
Luo, M.1
Delaplane, S.2
Jiang, A.3
Reed, A.4
He, Y.5
Fishel, M.6
Nyland II, R.L.7
Borch, R.F.8
Qiao, X.9
Georgiadis, M.M.10
Kelley, M.R.11
-
46
-
-
0027324056
-
Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
-
Walker LJ, Robson CN, Black E, Gillespie D, Hickson ID 1993 Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Mol Cell Biol 13:5370-5376 (Pubitemid 23260640)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.9
, pp. 5370-5376
-
-
Walker, L.J.1
Robson, C.N.2
Black, E.3
Gillespie, D.4
Hickson, I.D.5
-
47
-
-
17644365775
-
Two essential but distinct functions of the mammalian abasic endonuclease
-
DOI 10.1073/pnas.0500986102
-
Izumi T, Brown DB, Naidu CV, Bhakat KK, Macinnes MA, Saito H, Chen DJ, Mitra S 2005 Two essential but distinct functions of the mammalian abasic endonuclease. Proc Natl Acad Sci USA 102:5739-5743 (Pubitemid 40559629)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.16
, pp. 5739-5743
-
-
Izumi, T.1
Brown, D.B.2
Naidu, C.V.3
Bhakat, K.K.4
MacInnes, M.A.5
Saito, H.6
Chen, D.J.7
Mitra, S.8
-
48
-
-
49049087691
-
Evolution of the redox function in mammalian apurinic/ apyrimidinic endonuclease
-
Georgiadis MM, Luo M, Gaur RK, Delaplane S, Li X, Kelley MR 2008 Evolution of the redox function in mammalian apurinic/ apyrimidinic endonuclease. Mutat Res 643:54-63
-
(2008)
Mutat Res
, vol.643
, pp. 54-63
-
-
Georgiadis, M.M.1
Luo, M.2
Gaur, R.K.3
Delaplane, S.4
Li, X.5
Kelley, M.R.6
-
49
-
-
0034713821
-
Mol DNA-binding domain prevents dimerization and, hence, DNA binding
-
Whittal RM, Benz CC, Scott G, Semyonov J, Burlingame AL, Baldwin MA 2000 mol DNA-binding domain prevents dimerization and, hence, DNA binding. Biochemistry 39:8406-8417
-
(2000)
Biochemistry
, vol.39
, pp. 8406-8417
-
-
Whittal, R.M.1
Benz, C.C.2
Scott, G.3
Semyonov, J.4
Burlingame, A.L.5
Baldwin, M.A.6
-
50
-
-
0026714672
-
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
-
Xanthoudakis S, Miao G, Wang F, Pan YC, Curran T 1992 Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J 11:3323-3335
-
(1992)
EMBO J
, vol.11
, pp. 3323-3335
-
-
Xanthoudakis, S.1
Miao, G.2
Wang, F.3
Pan, Y.C.4
Curran, T.5
-
51
-
-
0034681378
-
A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1α and the HIF-like factor
-
DOI 10.1074/jbc.275.7.4618
-
Lando D, Pongratz I, Poellinger L, Whitelaw ML 2000 A redox mechanism controls differentialDNAbinding activities of hypoxia-inducible factor (HIF) 1α and the HIF-like factor. J Biol Chem 275:4618-4627 (Pubitemid 30108846)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.7
, pp. 4618-4627
-
-
Lando, D.1
Pongratz, I.2
Poellinger, L.3
Whitelaw, M.L.4
-
52
-
-
0036892182
-
Estrogen receptor α and activating protein-1 mediate estrogen responsiveness of the progesterone receptor gene in MCF-7 breast cancer cells
-
Petz LN, Ziegler YS, Loven MA, Nardulli AM 2002 Estrogen receptor α and activating protein-1 mediate estrogen responsiveness of the progesterone receptor gene in MCF-7 breast cancer cells. Endocrinology 143:4583-4591
-
(2002)
Endocrinology
, vol.143
, pp. 4583-4591
-
-
Petz, L.N.1
Ziegler, Y.S.2
Loven, M.A.3
Nardulli, A.M.4
-
53
-
-
1542297621
-
Fos and Jun inhibit estrogen-induced transcription of the human progesterone receptor gene through an activator protein-1 site
-
Petz LN, Ziegler YS, Schultz JR, Nardulli AM 2004 Fos and Jun inhibit estrogen-induced transcription of the human progesterone receptor gene through an activator protein-1 site. Mol Endocrinol 18:521-532
-
(2004)
Mol Endocrinol
, vol.18
, pp. 521-532
-
-
Petz, L.N.1
Ziegler, Y.S.2
Schultz, J.R.3
Nardulli, A.M.4
-
54
-
-
12844262221
-
Cell- and ligand-specific regulation of promoters containing activator protein-1 and Sp1 sites by estrogen receptors α and β
-
Schultz JR, Petz LN, Nardulli AM 2005 Cell- and ligand-specific regulation of promoters containing activator protein-1 and Sp1 sites by estrogen receptors α and β. J Biol Chem 280:347-354
-
(2005)
J Biol Chem
, vol.280
, pp. 347-354
-
-
Schultz, J.R.1
Petz, L.N.2
Nardulli, A.M.3
-
55
-
-
69449093242
-
Thioredoxin and thioredoxin reductase influence estrogen receptor α mediated gene expression in human breast cancer cells
-
20 July 10.1677/JME-09-0053
-
Rao AK, Ziegler YS, McLeod IX, Yates JR, Nardulli AM 20 July 2009 Thioredoxin and thioredoxin reductase influence estrogen receptor α mediated gene expression in human breast cancer cells. J Mol Endocrinol 10.1677/JME-09-0053
-
(2009)
J Mol Endocrinol
-
-
Rao, A.K.1
Ziegler, Y.S.2
McLeod, I.X.3
Yates, J.R.4
Nardulli, A.M.5
-
56
-
-
0029053451
-
Superoxide radical and superoxide dismutases
-
Fridovich I 1995 Superoxide radical and superoxide dismutases. Annu Rev Biochem 64:97-112
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 97-112
-
-
Fridovich, I.1
-
57
-
-
33749563294
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
-
DOI 10.1074/jbc.M603393200
-
Atkin JD, Farg MA, Turner BJ, Tomas D, Lysaght JA, Nunan J, Rembach A, Nagley P, Beart PM, Cheema SS, Horne MK 2006 Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. J Biol Chem 281:30152-30165 (Pubitemid 44537023)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 30152-30165
-
-
Atkin, J.D.1
Farg, M.A.2
Turner, B.J.3
Tomas, D.4
Lysaght, J.A.5
Nunan, J.6
Rembach, A.7
Nagley, P.8
Beart, P.M.9
Cheema, S.S.10
Horne, M.K.11
-
60
-
-
0029187491
-
Thioredoxin and thioredoxin reductase
-
Holmgren A, Björnstedt M 1995 Thioredoxin and thioredoxin reductase. Methods Enzymol 252:199-208
-
(1995)
Methods Enzymol
, vol.252
, pp. 199-208
-
-
Holmgren, A.1
Björnstedt, M.2
-
62
-
-
0025972887
-
Catalysis of the oxidative folding of ribonuclease A by protein disulfide isomerase: Pre-steady-state kinetics and the utilization of the oxidizing equivalents of the isomerase
-
Lyles MM, Gilbert HF 1991 Catalysis of the oxidative folding of ribonuclease A by protein disulfide isomerase: pre-steady-state kinetics and the utilization of the oxidizing equivalents of the isomerase. Biochemistry 30:619-625
-
(1991)
Biochemistry
, vol.30
, pp. 619-625
-
-
Lyles, M.M.1
Gilbert, H.F.2
-
63
-
-
0027220866
-
Peptide binding to protein disulfide isomerase occurs at a site distinct from the active sites
-
Noiva R, Freedman RB, Lennarz WJ 1993 Peptide binding to protein disulfide isomerase occurs at a site distinct from the active sites. J Biol Chem 268:19210-19217 (Pubitemid 23270690)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.26
, pp. 19210-19217
-
-
Noiva, R.1
Freedman, R.B.2
Lennarz, W.J.3
-
64
-
-
0028242359
-
The role of the thiol/disulfide centers and peptide binding site in the chaperone and anti-chaperone activities of protein disulfide isomerase
-
Puig A, Lyles MM, Noiva R, Gilbert HF 1994 The role of the thiol/disulfide centers and peptide binding site in the chaperone and anti-chaperone activities of protein disulfide isomerase. J Biol Chem 269:19128-19135 (Pubitemid 24226236)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.29
, pp. 19128-19135
-
-
Puig, A.1
Lyles, M.M.2
Noiva, R.3
Gilbert, H.F.4
-
65
-
-
0027136018
-
Protein disulfide isomerase is both an enzyme and a chaperone
-
Wang CC, Tsou CL 1993 Protein disulfide isomerase is both an enzyme and a chaperone. FASEB J 7:1515-1517 (Pubitemid 24003272)
-
(1993)
FASEB Journal
, vol.7
, Issue.15
, pp. 1515-1517
-
-
Wang, C.-C.1
Tsou, C.-L.2
-
66
-
-
0029146852
-
Independence of the chaperone activity of protein disulfide isomerase from its thioredoxin-like active site
-
Quan H, Fan G, Wang CC 1995 Independence of the chaperone activity of protein disulfide isomerase from its thioredoxin-like active site. J Biol Chem 270:17078-17080
-
(1995)
J Biol Chem
, vol.270
, pp. 17078-17080
-
-
Quan, H.1
Fan, G.2
Wang, C.C.3
-
67
-
-
0034719372
-
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
-
Nature [Erratum (2000) 404:6777]
-
Mol CD, Izumi T, Mitra S, Tainer JA 2000 DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination Nature [Erratum (2000) 404:6777] Nature 403:451-456
-
(2000)
Nature
, vol.403
, pp. 451-456
-
-
Mol, C.D.1
Izumi, T.2
Mitra, S.3
Tainer, J.A.4
-
68
-
-
0034093291
-
Passing the baton in base excision repair
-
DOI 10.1038/73260
-
Wilson SH, Kunkel TA 2000 Passing the baton in base excision repair. Nat Struct Biol 7:176-178 (Pubitemid 30140755)
-
(2000)
Nature Structural Biology
, vol.7
, Issue.3
, pp. 176-178
-
-
Wilson, S.H.1
Kunkel, T.A.2
-
69
-
-
1942425955
-
Interaction of estrogen receptor α with 3-methyladenine DNA glycosylase modulates transcription and DNA repair
-
Likhite VS, Cass EI, Anderson SD, Yates JR, Nardulli AM 2004 Interaction of estrogen receptor α with 3-methyladenine DNA glycosylase modulates transcription and DNA repair. J Biol Chem 279:16875-16882
-
(2004)
J Biol Chem
, vol.279
, pp. 16875-16882
-
-
Likhite, V.S.1
Cass, E.I.2
Anderson, S.D.3
Yates, J.R.4
Nardulli, A.M.5
-
71
-
-
0344642617
-
Preferential DNA repair of an active gene in human cells
-
Mellon I, Bohr VA, Smith CA, Hanawalt PC 1986 Preferential DNA repair of an active gene in human cells. Proc Natl Acad Sci USA 83:8878-8882 (Pubitemid 17223504)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.23
, pp. 8878-8882
-
-
Mellon, I.1
Bohr, V.A.2
Smith, C.A.3
Hanawalt, P.C.4
-
72
-
-
0023663101
-
Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene
-
Mellon I, Spivak G, Hanawalt PC 1987 Selective removal of transcription- blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51:241-249
-
(1987)
Cell
, vol.51
, pp. 241-249
-
-
Mellon, I.1
Spivak, G.2
Hanawalt, P.C.3
-
73
-
-
0034813581
-
The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage
-
Teo AK, Oh HK, Ali RB, Li BF 2001 The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage. Mol Cell Biol 21:7105-7114
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7105-7114
-
-
Teo, A.K.1
Oh, H.K.2
Ali, R.B.3
Li, B.F.4
-
74
-
-
33745255099
-
A topoisomerase IIβ-mediated dsDNA break required for regulated transcription
-
DOI 10.1126/science.1127196
-
Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG 2006 A topoisomerase IIβ-mediated dsDNA break required for regulated transcription. Science 312:1798-1802 (Pubitemid 43962898)
-
(2006)
Science
, vol.312
, Issue.5781
, pp. 1798-1802
-
-
Ju, B.-G.1
Lunyak, V.V.2
Perissi, V.3
Garcia-Bassets, I.4
Rose, D.W.5
Glass, C.K.6
Rosenfeld, M.G.7
-
75
-
-
35948976905
-
Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor α alters estrogen-responsive gene expression
-
Curtis CD, Likhite VS, McLeod IX, Yates JR, Nardulli AM 2007 Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor α alters estrogen-responsive gene expression. Cancer Res 67:10600-10607
-
(2007)
Cancer Res
, vol.67
, pp. 10600-10607
-
-
Curtis, C.D.1
Likhite, V.S.2
McLeod, I.X.3
Yates, J.R.4
Nardulli, A.M.5
-
77
-
-
0030585150
-
The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal
-
Qin J, Clore GM, Kennedy WP, Kuszewski J, Gronenborn AM 1996 The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal. Structure 4:613-620 (Pubitemid 126657553)
-
(1996)
Structure
, vol.4
, Issue.5
, pp. 613-620
-
-
Qin, J.1
Clore, G.M.2
Kennedy, W.P.3
Kuszewski, J.4
Gronenborn, A.M.5
-
78
-
-
48349107170
-
A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity
-
Ando K, Hirao S, Kabe Y, Ogura Y, Sato I, Yamaguchi Y, Wada T, Handa H 2008 A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Res 36:4327-4336
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4327-4336
-
-
Ando, K.1
Hirao, S.2
Kabe, Y.3
Ogura, Y.4
Sato, I.5
Yamaguchi, Y.6
Wada, T.7
Handa, H.8
-
79
-
-
0034544555
-
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation
-
Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, Laszlo A, Spitz DR, Goswami PC, Yodoi J, Gius D 2000 Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation. Cancer Res 60:6688-6695
-
(2000)
Cancer Res
, vol.60
, pp. 6688-6695
-
-
Wei, S.J.1
Botero, A.2
Hirota, K.3
Bradbury, C.M.4
Markovina, S.5
Laszlo, A.6
Spitz, D.R.7
Goswami, P.C.8
Yodoi, J.9
Gius, D.10
|