-
1
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., Dewhirst M.W., Bigner D.D., and Rich J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444 (2006) 756-760
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
2
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao S., Wu Q., Sathornsumetee S., Hao Y., Li Z., Hjelmeland A.B., Shi Q., McLendon R.E., Bigner D.D., and Rich J.N. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 66 (2006) 7843-7848
-
(2006)
Cancer Res.
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
Hao, Y.4
Li, Z.5
Hjelmeland, A.B.6
Shi, Q.7
McLendon, R.E.8
Bigner, D.D.9
Rich, J.N.10
-
3
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao S., Wu Q., Li Z., Sathornsumetee S., Wang H., McLendon R.E., Hjelmeland A.B., and Rich J.N. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res. 68 (2008) 6043-6048
-
(2008)
Cancer Res.
, vol.68
, pp. 6043-6048
-
-
Bao, S.1
Wu, Q.2
Li, Z.3
Sathornsumetee, S.4
Wang, H.5
McLendon, R.E.6
Hjelmeland, A.B.7
Rich, J.N.8
-
4
-
-
34249332411
-
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
-
Beier D., Hau P., Proescholdt M., Lohmeier A., Wischhusen J., Oefner P.J., Aigner L., Brawanski A., Bogdahn U., and Beier C.P. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Ress 67 (2007) 4010-4015
-
(2007)
Cancer Ress
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
Lohmeier, A.4
Wischhusen, J.5
Oefner, P.J.6
Aigner, L.7
Brawanski, A.8
Bogdahn, U.9
Beier, C.P.10
-
5
-
-
33845621982
-
Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia
-
Blazek E.R., Foutch J.L., and Maki G. Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 67 (2007) 1-5
-
(2007)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.67
, pp. 1-5
-
-
Blazek, E.R.1
Foutch, J.L.2
Maki, G.3
-
6
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C., Poppleton H., Kocak M., Hogg T.L., Fuller C., Hamner B., Oh E.Y., Gaber M.W., Finklestein D., Allen M., et al. A perivascular niche for brain tumor stem cells. Cancer Cell 11 (2007) 69-82
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
Oh, E.Y.7
Gaber, M.W.8
Finklestein, D.9
Allen, M.10
-
7
-
-
4344571862
-
Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing
-
Cardenas-Navia L.I., Yu D., Braun R.D., Brizel D.M., Secomb T.W., and Dewhirst M.W. Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing. Cancer Res. 64 (2004) 6010-6017
-
(2004)
Cancer Res.
, vol.64
, pp. 6010-6017
-
-
Cardenas-Navia, L.I.1
Yu, D.2
Braun, R.D.3
Brizel, D.M.4
Secomb, T.W.5
Dewhirst, M.W.6
-
8
-
-
33644551073
-
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
-
Chi J.T., Wang Z., Nuyten D.S., Rodriguez E.H., Schaner M.E., Salim A., Wang Y., Kristensen G.B., Helland A., Borresen-Dale A.L., et al. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med. 3 (2006) e47
-
(2006)
PLoS Med.
, vol.3
-
-
Chi, J.T.1
Wang, Z.2
Nuyten, D.S.3
Rodriguez, E.H.4
Schaner, M.E.5
Salim, A.6
Wang, Y.7
Kristensen, G.B.8
Helland, A.9
Borresen-Dale, A.L.10
-
9
-
-
53349174906
-
CD133 identifies perivascular niches in grade II-IV astrocytomas
-
Christensen K., Schroder H.D., and Kristensen B.W. CD133 identifies perivascular niches in grade II-IV astrocytomas. J Neurooncol. 90 (2008) 157-170
-
(2008)
J Neurooncol.
, vol.90
, pp. 157-170
-
-
Christensen, K.1
Schroder, H.D.2
Kristensen, B.W.3
-
10
-
-
0035983324
-
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
-
Compernolle V., Brusselmans K., Acker T., Hoet P., Tjwa M., Beck H., Plaisance S., Dor Y., Keshet E., Lupu F., et al. Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat. Med. 8 (2002) 702-710
-
(2002)
Nat. Med.
, vol.8
, pp. 702-710
-
-
Compernolle, V.1
Brusselmans, K.2
Acker, T.3
Hoet, P.4
Tjwa, M.5
Beck, H.6
Plaisance, S.7
Dor, Y.8
Keshet, E.9
Lupu, F.10
-
11
-
-
33644747418
-
HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello K.L., Kehler J., Yu H., Gordan J.D., Arsham A.M., Hu C.J., Labosky P.A., Simon M.C., and Keith B. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev. 20 (2006) 557-570
-
(2006)
Genes Dev.
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
Gordan, J.D.4
Arsham, A.M.5
Hu, C.J.6
Labosky, P.A.7
Simon, M.C.8
Keith, B.9
-
12
-
-
85047692887
-
Expansion of human SCID-repopulating cells under hypoxic conditions
-
Danet G.H., Pan Y., Luongo J.L., Bonnet D.A., and Simon M.C. Expansion of human SCID-repopulating cells under hypoxic conditions. J. Clin. Invest. 112 (2003) 126-135
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 126-135
-
-
Danet, G.H.1
Pan, Y.2
Luongo, J.L.3
Bonnet, D.A.4
Simon, M.C.5
-
13
-
-
16344380951
-
Low O2 tensions and the prevention of differentiation of hES cells
-
Ezashi T., Das P., and Roberts R.M. Low O2 tensions and the prevention of differentiation of hES cells. Proc. Natl. Acad. Sci. USA 102 (2005) 4783-4788
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4783-4788
-
-
Ezashi, T.1
Das, P.2
Roberts, R.M.3
-
14
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R., Binda E., Orfanelli U., Cipelletti B., Gritti A., De Vitis S., Fiocco R., Foroni C., Dimeco F., and Vescovi A. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 64 (2004) 7011-7021
-
(2004)
Cancer Res.
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
15
-
-
0029866447
-
Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells
-
Gassmann M., Fandrey J., Bichet S., Wartenberg M., Marti H.H., Bauer C., Wenger R.H., and Acker H. Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells. Proc. Natl. Acad. Sci. USA 93 (1996) 2867-2872
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2867-2872
-
-
Gassmann, M.1
Fandrey, J.2
Bichet, S.3
Wartenberg, M.4
Marti, H.H.5
Bauer, C.6
Wenger, R.H.7
Acker, H.8
-
16
-
-
34648821254
-
Making a tumour's bed: GSCs and the vascular niche
-
Gilbertson R.J., and Rich J.N. Making a tumour's bed: GSCs and the vascular niche. Nat. Rev. Cancer 7 (2007) 733-736
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
17
-
-
34047156190
-
HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
-
Gordan J.D., Bertout J.A., Hu C.J., Diehl J.A., and Simon M.C. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell 11 (2007) 335-347
-
(2007)
Cancer Cell
, vol.11
, pp. 335-347
-
-
Gordan, J.D.1
Bertout, J.A.2
Hu, C.J.3
Diehl, J.A.4
Simon, M.C.5
-
18
-
-
33845226457
-
Radiation resistance and stem-like cells in brain tumors
-
Hambardzumyan D., Squatrito M., and Holland E.C. Radiation resistance and stem-like cells in brain tumors. Cancer Cell 10 (2006) 454-456
-
(2006)
Cancer Cell
, vol.10
, pp. 454-456
-
-
Hambardzumyan, D.1
Squatrito, M.2
Holland, E.C.3
-
19
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris A.L. Hypoxia-a key regulatory factor in tumour growth. Nat. Rev. Cancer 2 (2002) 38-47
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
20
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati H.D., Nakano I., Lazareff J.A., Masterman-Smith M., Geschwind D.H., Bronner-Fraser M., and Kornblum H.I. Cancerous stem cells can arise from pediatric brain tumors. Proc. Natl. Acad. Sci. USA 100 (2003) 15178-15183
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
Masterman-Smith, M.4
Geschwind, D.H.5
Bronner-Fraser, M.6
Kornblum, H.I.7
-
21
-
-
33750630119
-
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype
-
Holmquist-Mengelbier L., Fredlund E., Lofstedt T., Noguera R., Navarro S., Nilsson H., Pietras A., Vallon-Christersson J., Borg A., Gradin K., et al. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell 10 (2006) 413-423
-
(2006)
Cancer Cell
, vol.10
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Lofstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
-
22
-
-
33646248422
-
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells
-
Hu C.J., Iyer S., Sataur A., Covello K.L., Chodosh L.A., and Simon M.C. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol. Cell. Biol. 26 (2006) 3514-3526
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3514-3526
-
-
Hu, C.J.1
Iyer, S.2
Sataur, A.3
Covello, K.L.4
Chodosh, L.A.5
Simon, M.C.6
-
23
-
-
53049104709
-
Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis
-
Hu T., Liu S., Breiter D.R., Wang F., Tang Y., and Sun S. Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res. 68 (2008) 6533-6540
-
(2008)
Cancer Res.
, vol.68
, pp. 6533-6540
-
-
Hu, T.1
Liu, S.2
Breiter, D.R.3
Wang, F.4
Tang, Y.5
Sun, S.6
-
24
-
-
0024404034
-
Effects of physiological oxygen environment on drug-induced cell lethality of multicellular tumor spheroids from human lung cancer
-
Inoue S., and Ohnuma T. Effects of physiological oxygen environment on drug-induced cell lethality of multicellular tumor spheroids from human lung cancer. Sel. Cancer Ther. 5 (1989) 13-22
-
(1989)
Sel. Cancer Ther.
, vol.5
, pp. 13-22
-
-
Inoue, S.1
Ohnuma, T.2
-
25
-
-
34447632643
-
Angiogenesis in brain tumours
-
Jain R.K., di Tomaso E., Duda D.G., Loeffler J.S., Sorensen A.G., and Batchelor T.T. Angiogenesis in brain tumours. Nat. Rev. Neurosci. 8 (2007) 610-622
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 610-622
-
-
Jain, R.K.1
di Tomaso, E.2
Duda, D.G.3
Loeffler, J.S.4
Sorensen, A.G.5
Batchelor, T.T.6
-
26
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
Jin L., Hope K.J., Zhai Q., Smadja-Joffe F., and Dick J.E. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 12 (2006) 1167-1174
-
(2006)
Nat. Med.
, vol.12
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
27
-
-
17844371306
-
Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis
-
Kaur B., Khwaja F.W., Severson E.A., Matheny S.L., Brat D.J., and Van Meir E.G. Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro-oncol. 7 (2005) 134-153
-
(2005)
Neuro-oncol.
, vol.7
, pp. 134-153
-
-
Kaur, B.1
Khwaja, F.W.2
Severson, E.A.3
Matheny, S.L.4
Brat, D.J.5
Van Meir, E.G.6
-
28
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith B., and Simon M.C. Hypoxia-inducible factors, stem cells, and cancer. Cell 129 (2007) 465-472
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
29
-
-
41149109622
-
Uncertainty in the niches that maintain haematopoietic stem cells
-
Kiel M.J., and Morrison S.J. Uncertainty in the niches that maintain haematopoietic stem cells. Nat. Rev. Immunol. 8 (2008) 290-301
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 290-301
-
-
Kiel, M.J.1
Morrison, S.J.2
-
30
-
-
0030476061
-
Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma
-
Kimura H., Braun R.D., Ong E.T., Hsu R., Secomb T.W., Papahadjopoulos D., Hong K., and Dewhirst M.W. Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. Cancer Res. 56 (1996) 5522-5528
-
(1996)
Cancer Res.
, vol.56
, pp. 5522-5528
-
-
Kimura, H.1
Braun, R.D.2
Ong, E.T.3
Hsu, R.4
Secomb, T.W.5
Papahadjopoulos, D.6
Hong, K.7
Dewhirst, M.W.8
-
31
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
-
Li X., Lewis M.T., Huang J., Gutierrez C., Osborne C.K., Wu M.F., Hilsenbeck S.G., Pavlick A., Zhang X., Chamness G.C., et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J. Natl. Cancer Inst. 100 (2008) 672-679
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
Gutierrez, C.4
Osborne, C.K.5
Wu, M.F.6
Hilsenbeck, S.G.7
Pavlick, A.8
Zhang, X.9
Chamness, G.C.10
-
32
-
-
0030056563
-
Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines
-
Liang B.C. Effects of hypoxia on drug resistance phenotype and genotype in human glioma cell lines. J. Neurooncol. 29 (1996) 149-155
-
(1996)
J. Neurooncol.
, vol.29
, pp. 149-155
-
-
Liang, B.C.1
-
33
-
-
33846815345
-
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
-
Ligon K.L., Huillard E., Mehta S., Kesari S., Liu H., Alberta J.A., Bachoo R.M., Kane M., Louis D.N., Depinho R.A., et al. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 53 (2007) 503-517
-
(2007)
Neuron
, vol.53
, pp. 503-517
-
-
Ligon, K.L.1
Huillard, E.2
Mehta, S.3
Kesari, S.4
Liu, H.5
Alberta, J.A.6
Bachoo, R.M.7
Kane, M.8
Louis, D.N.9
Depinho, R.A.10
-
34
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
Liu G., Yuan X., Zeng Z., Tunici P., Ng H., Abdulkadir I.R., Lu L., Irvin D., Black K.L., and Yu J.S. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol. Cancer 5 (2006) 67
-
(2006)
Mol. Cancer
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
Lu, L.7
Irvin, D.8
Black, K.L.9
Yu, J.S.10
-
35
-
-
12944262229
-
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
-
Macheda M.L., Rogers S., and Best J.D. Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J. Cell. Physiol. 202 (2005) 654-662
-
(2005)
J. Cell. Physiol.
, vol.202
, pp. 654-662
-
-
Macheda, M.L.1
Rogers, S.2
Best, J.D.3
-
36
-
-
0037520693
-
Stem cell pluripotency and transcription factor Oct4
-
Pan G.J., Chang Z.Y., Scholer H.R., and Pei D. Stem cell pluripotency and transcription factor Oct4. Cell Res. 12 (2002) 321-329
-
(2002)
Cell Res.
, vol.12
, pp. 321-329
-
-
Pan, G.J.1
Chang, Z.Y.2
Scholer, H.R.3
Pei, D.4
-
37
-
-
34248359065
-
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
-
Parmar K., Mauch P., Vergilio J.A., Sackstein R., and Down J.D. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl. Acad. Sci. USA 104 (2007) 5431-5436
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 5431-5436
-
-
Parmar, K.1
Mauch, P.2
Vergilio, J.A.3
Sackstein, R.4
Down, J.D.5
-
38
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate K.H., Breier G., Weich H.A., and Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359 (1992) 845-848
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Risau, W.4
-
39
-
-
36148995870
-
Influence of oxygen tension on CD133 phenotype in human glioma cell cultures
-
Platet N., Liu S.Y., Atifi M.E., Oliver L., Vallette F.M., Berger F., and Wion D. Influence of oxygen tension on CD133 phenotype in human glioma cell cultures. Cancer Lett. 258 (2007) 286-290
-
(2007)
Cancer Lett.
, vol.258
, pp. 286-290
-
-
Platet, N.1
Liu, S.Y.2
Atifi, M.E.3
Oliver, L.4
Vallette, F.M.5
Berger, F.6
Wion, D.7
-
40
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J., Dayan F., and Mazure N.M. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441 (2006) 437-443
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
41
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E., Shackleton M., Sabel M.S., Fullen D.R., Johnson T.M., and Morrison S.J. Efficient tumour formation by single human melanoma cells. Nature 456 (2008) 593-598
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
42
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
Raval R.R., Lau K.W., Tran M.G., Sowter H.M., Mandriota S.J., Li J.L., Pugh C.W., Maxwell P.H., Harris A.L., and Ratcliffe P.J. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol. Cell. Biol. 25 (2005) 5675-5686
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.3
Sowter, H.M.4
Mandriota, S.J.5
Li, J.L.6
Pugh, C.W.7
Maxwell, P.H.8
Harris, A.L.9
Ratcliffe, P.J.10
-
43
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., and Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
44
-
-
38349155463
-
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan
-
Sathornsumetee S., Cao Y., Marcello J.E., Herndon II J.E., McLendon R.E., Desjardins A., Friedman H.S., Dewhirst M.W., Vredenburgh J.J., and Rich J.N. Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. J. Clin. Oncol. 26 (2008) 271-278
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 271-278
-
-
Sathornsumetee, S.1
Cao, Y.2
Marcello, J.E.3
Herndon II, J.E.4
McLendon, R.E.5
Desjardins, A.6
Friedman, H.S.7
Dewhirst, M.W.8
Vredenburgh, J.J.9
Rich, J.N.10
-
45
-
-
2342661143
-
Intratumoral hypoxia, radiation resistance, and HIF-1
-
Semenza G.L. Intratumoral hypoxia, radiation resistance, and HIF-1. Cancer Cell 5 (2004) 405-406
-
(2004)
Cancer Cell
, vol.5
, pp. 405-406
-
-
Semenza, G.L.1
-
46
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh S.K., Clarke I.D., Terasaki M., Bonn V.E., Hawkins C., Squire J., and Dirks P.B. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63 (2003) 5821-5828
-
(2003)
Cancer Res.
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
47
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh S.K., Hawkins C., Clarke I.D., Squire J.A., Bayani J., Hide T., Henkelman R.M., Cusimano M.D., and Dirks P.B. Identification of human brain tumour initiating cells. Nature 432 (2004) 396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
48
-
-
53549130485
-
White fat progenitor cells reside in the adipose vasculature
-
Tang W., Zeve D., Suh J.M., Bosnakovski D., Kyba M., Hammer R.E., Tallquist M.D., and Graff J.M. White fat progenitor cells reside in the adipose vasculature. Science 322 (2008) 583-586
-
(2008)
Science
, vol.322
, pp. 583-586
-
-
Tang, W.1
Zeve, D.2
Suh, J.M.3
Bosnakovski, D.4
Kyba, M.5
Hammer, R.E.6
Tallquist, M.D.7
Graff, J.M.8
-
49
-
-
0028307739
-
Hypoxia and drug resistance
-
Teicher B.A. Hypoxia and drug resistance. Cancer Metastasis Rev. 13 (1994) 139-168
-
(1994)
Cancer Metastasis Rev.
, vol.13
, pp. 139-168
-
-
Teicher, B.A.1
-
50
-
-
34848866647
-
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
-
Todaro M., Alea M.P., Di Stefano A.B., Cammareri P., Vermeulen L., Iovino F., Tripodo C., Russo A., Gulotta G., Medema J.P., et al. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. Cell Stem Cell 1 (2007) 389-402
-
(2007)
Cell Stem Cell
, vol.1
, pp. 389-402
-
-
Todaro, M.1
Alea, M.P.2
Di Stefano, A.B.3
Cammareri, P.4
Vermeulen, L.5
Iovino, F.6
Tripodo, C.7
Russo, A.8
Gulotta, G.9
Medema, J.P.10
-
51
-
-
0141669198
-
Defective brain development in mice lacking the Hif-1alpha gene in neural cells
-
Tomita S., Ueno M., Sakamoto M., Kitahama Y., Ueki M., Maekawa N., Sakamoto H., Gassmann M., Kageyama R., Ueda N., et al. Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol. Cell. Biol. 23 (2003) 6739-6749
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6739-6749
-
-
Tomita, S.1
Ueno, M.2
Sakamoto, M.3
Kitahama, Y.4
Ueki, M.5
Maekawa, N.6
Sakamoto, H.7
Gassmann, M.8
Kageyama, R.9
Ueda, N.10
-
52
-
-
0141629530
-
Granzyme B: pro-apoptotic, antiviral and antitumor functions
-
Trapani J.A., and Sutton V.R. Granzyme B: pro-apoptotic, antiviral and antitumor functions. Curr. Opin. Immunol. 15 (2003) 533-543
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 533-543
-
-
Trapani, J.A.1
Sutton, V.R.2
-
53
-
-
24344490223
-
Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma
-
van Houdt I.S., Oudejans J.J., van den Eertwegh A.J., Baars A., Vos W., Bladergroen B.A., Rimoldi D., Muris J.J., Hooijberg E., Gundy C.M., et al. Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma. Clin. Cancer Res. 11 (2005) 6400-6407
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 6400-6407
-
-
van Houdt, I.S.1
Oudejans, J.J.2
van den Eertwegh, A.J.3
Baars, A.4
Vos, W.5
Bladergroen, B.A.6
Rimoldi, D.7
Muris, J.J.8
Hooijberg, E.9
Gundy, C.M.10
-
54
-
-
34547121206
-
Hypoxia in cancer: significance and impact on clinical outcome
-
Vaupel P., and Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev. 26 (2007) 225-239
-
(2007)
Cancer Metastasis Rev.
, vol.26
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
56
-
-
0027136260
-
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction
-
Wang G.L., and Semenza G.L. Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood 82 (1993) 3610-3615
-
(1993)
Blood
, vol.82
, pp. 3610-3615
-
-
Wang, G.L.1
Semenza, G.L.2
-
57
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
Wang J., Rao S., Chu J., Shen X., Levasseur D.N., Theunissen T.W., and Orkin S.H. A protein interaction network for pluripotency of embryonic stem cells. Nature 444 (2006) 364-368
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
Shen, X.4
Levasseur, D.N.5
Theunissen, T.W.6
Orkin, S.H.7
-
58
-
-
38349075007
-
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells
-
Wang J., Sakariassen P.Ø., Tsinkalovsky O., Immervoll H., Bøe S.O., Svendsen A., Prestegarden L., Røsland G., Thorsen F., Stuhr L., et al. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int. J. Cancer 122 (2008) 761-768
-
(2008)
Int. J. Cancer
, vol.122
, pp. 761-768
-
-
Wang, J.1
Sakariassen, P.Ø.2
Tsinkalovsky, O.3
Immervoll, H.4
Bøe, S.O.5
Svendsen, A.6
Prestegarden, L.7
Røsland, G.8
Thorsen, F.9
Stuhr, L.10
-
59
-
-
0035883060
-
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
-
Wulf G.G., Wang R.Y., Kuehnle I., Weidner D., Marini F., Brenner M.K., Andreeff M., and Goodell M.A. A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 98 (2001) 1166-1173
-
(2001)
Blood
, vol.98
, pp. 1166-1173
-
-
Wulf, G.G.1
Wang, R.Y.2
Kuehnle, I.3
Weidner, D.4
Marini, F.5
Brenner, M.K.6
Andreeff, M.7
Goodell, M.A.8
-
60
-
-
34648812826
-
A vasculature-associated niche for undifferentiated spermatogonia in the mouse testis
-
Yoshida S., Sukeno M., and Nabeshima Y. A vasculature-associated niche for undifferentiated spermatogonia in the mouse testis. Science 317 (2007) 1722-1726
-
(2007)
Science
, vol.317
, pp. 1722-1726
-
-
Yoshida, S.1
Sukeno, M.2
Nabeshima, Y.3
-
61
-
-
0029554059
-
GLUT1 expression in human breast carcinoma: correlation with known prognostic markers
-
Younes M., Brown R.W., Mody D.R., Fernandez L., and Laucirica R. GLUT1 expression in human breast carcinoma: correlation with known prognostic markers. Anticancer Res. 15 (1995) 2895-2898
-
(1995)
Anticancer Res.
, vol.15
, pp. 2895-2898
-
-
Younes, M.1
Brown, R.W.2
Mody, D.R.3
Fernandez, L.4
Laucirica, R.5
-
62
-
-
0034194055
-
The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells
-
Young J.L., Sukhova G.K., Foster D., Kisiel W., Libby P., and Schonbeck U. The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells. J. Exp. Med. 191 (2000) 1535-1544
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1535-1544
-
-
Young, J.L.1
Sukhova, G.K.2
Foster, D.3
Kisiel, W.4
Libby, P.5
Schonbeck, U.6
-
63
-
-
34248547533
-
Most C6 cells are cancer stem cells: evidence from clonal and population analyses
-
Zheng X., Shen G., Yang X., and Liu W. Most C6 cells are cancer stem cells: evidence from clonal and population analyses. Cancer Res. 67 (2007) 3691-3697
-
(2007)
Cancer Res.
, vol.67
, pp. 3691-3697
-
-
Zheng, X.1
Shen, G.2
Yang, X.3
Liu, W.4
|