Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1

Antioxidants and Redox Signaling

Volumn 14, Issue 8, 2011, Pages 1387-1401

  Kelley, Mark R ^a,b   Luo, Meihua ^a   Reed, April ^a   Su, Dian ^c   Delaplane, Sarah ^b   Borch, Richard F ^d   Nyland, Rodney L ^d   Gross, Michael L ^c   Georgiadis, Millie M ^b,e  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Biochemistry and Molecular Biology ^*  (United States)

^c WASHINGTON UNIVERSITY   (United States)

^d PURDUE UNIVERSITY   (United States)

^e INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; E 3330; ENDONUCLEASE; REDOX EFFECTOR FACTOR 1; RN 10 52; RN 7 60; RN 8 51; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DNA REPAIR; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENDOTHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GROWTH INHIBITION; IC 50; MASS SPECTROMETRY; NICK END LABELING; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANTINEOPLASTIC AGENTS; BENZOQUINONES; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CLONING, MOLECULAR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANIZATION AND ADMINISTRATION; OXIDATION-REDUCTION; PROPIONIC ACIDS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79952833556     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2010.3410     Document Type: Article

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