Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment

Cellular and Molecular Life Sciences

Volumn 67, Issue 21, 2010, Pages 3589-3608

  Tell, Gianluca ^a   Fantini, Damiano ^a   Quadrifoglio, Franco ^a  

^a UNIVERSITY OF UDINE   (Italy)

Author keywords

Base excision repair; Cancer; Nucleolus; Oxidative stress; Redox signalling

Indexed keywords

BLEOMYCIN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; E 3330; GEMCITABINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; ISOFLAVONE; QUINONE DERIVATIVE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RESVERATROL; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; CALCIUM MOBILIZATION; CANCER THERAPY; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; DNA REPAIR; EXCISION REPAIR; GENOTOXICITY; HUMAN; INTRACELLULAR TRANSPORT; LIVER CELL CARCINOMA; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; RNA METABOLISM; TRANSCRIPTION REGULATION;

ANIMALS; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; HUMANS; NEOPLASMS;

MAMMALIA;

EID: 78149471195     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0486-4     Document Type: Review

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