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Volumn 160, Issue 2, 1998, Pages 810-819

Nuclear targeted suppression of NF-κB activity by the novel quinone derivative E3330

Author keywords

[No Author keywords available]

Indexed keywords

3 [5 (2,3 DIMETHOXY 6 METHYL 1,4 BENZOQUINOYL)] 2 NONYL 2 PROPENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; QUINONE DERIVATIVE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 0031964618     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (68)
  • 1
    • 0024759789 scopus 로고
    • A 65-kD subunit of active NF-κB is required for inhibition of NF-κB by IκB
    • Baeuerle, P. A., and D. Baltimore. 1989. A 65-kD subunit of active NF-κB is required for inhibition of NF-κB by IκB. Genes Dev. 3:1689.
    • (1989) Genes Dev. , vol.3 , pp. 1689
    • Baeuerle, P.A.1    Baltimore, D.2
  • 2
    • 0025266685 scopus 로고
    • Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB
    • Ghosh, S., and D. Baltimore. 1990. Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature 344:678.
    • (1990) Nature , vol.344 , pp. 678
    • Ghosh, S.1    Baltimore, D.2
  • 4
    • 0025078530 scopus 로고
    • Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
    • Ghosh, S., A. M. Gifford, L. R. Riviere, P. Tempst, G. P. Nolan, and D. Baltimore. 1990. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 62:1019.
    • (1990) Cell , vol.62 , pp. 1019
    • Ghosh, S.1    Gifford, A.M.2    Riviere, L.R.3    Tempst, P.4    Nolan, G.P.5    Baltimore, D.6
  • 6
    • 0026331456 scopus 로고
    • B-Cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50
    • Neri, A., C. C. Chang, L. Lombardi, M. Salina, P. Corradini, A. T. Maiolo, R. S. K. Chaganti, and R. Dalla-Favera. 1991. B-Cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50. Cell 67:1075.
    • (1991) Cell , vol.67 , pp. 1075
    • Neri, A.1    Chang, C.C.2    Lombardi, L.3    Salina, M.4    Corradini, P.5    Maiolo, A.T.6    Chaganti, R.S.K.7    Dalla-Favera, R.8
  • 7
    • 0025975795 scopus 로고
    • DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a Rel-related polypeptide
    • Nolan, G. P., S. Ghosh, H. C. Liou, P. Tempst, and D. Baltimore. 1991. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a Rel-related polypeptide. Cell 64:961.
    • (1991) Cell , vol.64 , pp. 961
    • Nolan, G.P.1    Ghosh, S.2    Liou, H.C.3    Tempst, P.4    Baltimore, D.5
  • 9
    • 0026708393 scopus 로고
    • I-Rel: A novel rel-related protein that inhibits NF-κB transcriptional activity
    • Ruben, S. M., J. F. Klement, T. A. Coleman, M. Maher, C. H. Chen, and C. A. Rosen. 1992. I-Rel: a novel rel-related protein that inhibits NF-κB transcriptional activity. Genes Dev. 6:745.
    • (1992) Genes Dev. , vol.6 , pp. 745
    • Ruben, S.M.1    Klement, J.F.2    Coleman, T.A.3    Maher, M.4    Chen, C.H.5    Rosen, C.A.6
  • 10
    • 0025738076 scopus 로고
    • Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65
    • Schmid, R. M., N. D. Perkins, C. S. Duckett, P. C. Andrews, and G. J. Nabel. 1991. Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65. Nature 352:733.
    • (1991) Nature , vol.352 , pp. 733
    • Schmid, R.M.1    Perkins, N.D.2    Duckett, C.S.3    Andrews, P.C.4    Nabel, G.J.5
  • 11
    • 0026592340 scopus 로고
    • A novel complex between the p65 subunit of NF-κB and c-Rel binds to a DNa element involved in the phorbol ester induction of the human urokinase gene
    • Hansen, S. K., C. Nerlov, U. Zabel, P. Verde, M. Johnsen, P. A. Baeuerle, and F. Blasi. 1992. A novel complex between the p65 subunit of NF-κB and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene. EMBO J. 11:205.
    • (1992) EMBO J. , vol.11 , pp. 205
    • Hansen, S.K.1    Nerlov, C.2    Zabel, U.3    Verde, P.4    Johnsen, M.5    Baeuerle, P.A.6    Blasi, F.7
  • 14
    • 0025782658 scopus 로고
    • NF-κB contacts DNa by a heterodimer of the p50 and p65 subunit
    • Urban, M. B., R. Schreck, and P. A. Baeuerle. 1991. NF-κB contacts DNA by a heterodimer of the p50 and p65 subunit. EMBO J. 10:1817.
    • (1991) EMBO J. , vol.10 , pp. 1817
    • Urban, M.B.1    Schreck, R.2    Baeuerle, P.A.3
  • 15
    • 0026527184 scopus 로고
    • The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression
    • Ballard, D. W., E. P. Dixon, N. J. Peffer, H. Bogerd, S. Doerre, B. Stein, and W. C. Greene. 1992. The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc. Natl. Acad. Sci. USA 89:1875.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1875
    • Ballard, D.W.1    Dixon, E.P.2    Peffer, N.J.3    Bogerd, H.4    Doerre, S.5    Stein, B.6    Greene, W.C.7
  • 16
    • 0025184764 scopus 로고
    • The mouse c-Rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain
    • Bull, P., K. L. Morley, M. F. Hoekstra, T. Hunter, and I. M. Verma. 1990. The mouse c-Rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Mol. Cell. Biol. 10:5473.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5473
    • Bull, P.1    Morley, K.L.2    Hoekstra, M.F.3    Hunter, T.4    Verma, I.M.5
  • 17
    • 0026570254 scopus 로고
    • Functional characterisation of the NF-κB p65 transcriptional activator and an alternatively spliced derivative
    • Ruben, S. M., R. Narayanan, J. F. Klement, C-H. Chen, and C. A. Rosen. 1992. Functional characterisation of the NF-κB p65 transcriptional activator and an alternatively spliced derivative. Mol. Cell. Biol. 12:444.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 444
    • Ruben, S.M.1    Narayanan, R.2    Klement, J.F.3    Chen, C.-H.4    Rosen, C.A.5
  • 18
    • 0025943986 scopus 로고
    • The p65 subunit is responsible for the strong transcription activating potential of NF-κB
    • Schmitz, M. L., and P. A. Baeuerle. 1991. The p65 subunit is responsible for the strong transcription activating potential of NF-κB. EMBO J. 10:3805.
    • (1991) EMBO J. , vol.10 , pp. 3805
    • Schmitz, M.L.1    Baeuerle, P.A.2
  • 19
    • 0026708394 scopus 로고
    • Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB
    • Fujita, T., G. P. Nolan, S. Ghosh, and D. Baltimore. 1992. Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB. Genes Dev. 6:775.
    • (1992) Genes Dev. , vol.6 , pp. 775
    • Fujita, T.1    Nolan, G.P.2    Ghosh, S.3    Baltimore, D.4
  • 20
    • 0027232067 scopus 로고
    • NF-κB and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli, M., J. S. Chiu, and M. J. Lenardo. 1993. NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143:1.
    • (1993) Int. Rev. Cytol. , vol.143 , pp. 1
    • Grilli, M.1    Chiu, J.S.2    Lenardo, M.J.3
  • 21
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141
    • Baeuerle, P.A.1    Henkel, T.2
  • 23
    • 0027176524 scopus 로고
    • Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB
    • Henkel, T., T. Machleidt, I. Alkalay, M. Kronke, Y. Ben-Neriah, and P. A. Baeuerle. 1993. Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB. Nature 365:182.
    • (1993) Nature , vol.365 , pp. 182
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Kronke, M.4    Ben-Neriah, Y.5    Baeuerle, P.A.6
  • 24
    • 0027168447 scopus 로고
    • NF-κB controls expression of inhibitor IκBα: Evidence for an inducible autoregulatory pathway
    • Sun, S.-C., P. A. Ganchi, D. W. Ballard, and W. C. Greene. 1993. NF-κB controls expression of inhibitor IκBα: evidence for an inducible autoregulatory pathway. Science 259:1912.
    • (1993) Science , vol.259 , pp. 1912
    • Sun, S.-C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 25
    • 0028170265 scopus 로고
    • Activation of NF-κB in vivo is regulated by multiple phosphorylations
    • Naumann, M., and C. Scheidereit. 1994. Activation of NF-κB in vivo is regulated by multiple phosphorylations. EMBO J. 13:4597.
    • (1994) EMBO J. , vol.13 , pp. 4597
    • Naumann, M.1    Scheidereit, C.2
  • 26
    • 0026715172 scopus 로고
    • Thioredoxin regulates the DNa binding activity of NF-κB by reduction of a disulphide bond involving cystein 62
    • Matthews, J. R., N. Wakasugi, J.-L. Virelizier, J. Yodoi, and R. T. Hay. 1992. Thioredoxin regulates the DNA binding activity of NF-κB by reduction of a disulphide bond involving cystein 62. Nucleic Acids Res. 30:3821.
    • (1992) Nucleic Acids Res. , vol.30 , pp. 3821
    • Matthews, J.R.1    Wakasugi, N.2    Virelizier, J.-L.3    Yodoi, J.4    Hay, R.T.5
  • 27
    • 0026652879 scopus 로고
    • The RxxRxRxxC motif conserved in all Rel/κB proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein
    • Kumar, S., A. B. Rabson, and C. Gelinas. 1992. The RxxRxRxxC motif conserved in all Rel/κB proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein. Mol. Cell. Biol. 12:3094.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3094
    • Kumar, S.1    Rabson, A.B.2    Gelinas, C.3
  • 28
    • 0025852479 scopus 로고
    • Modulation of transcription factor NF-κB binding activity by oxdation-reduction in vitro
    • Toledano, M. B., and W. J. Leonhard. 1991. Modulation of transcription factor NF-κB binding activity by oxdation-reduction in vitro. Proc. Natl. Acad. Sci. USA 88:4328.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4328
    • Toledano, M.B.1    Leonhard, W.J.2
  • 29
    • 0026489365 scopus 로고
    • The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene
    • Thanos, D., and T. Maniatis. 1992. The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene. Cell 71: 777.
    • (1992) Cell , vol.71 , pp. 777
    • Thanos, D.1    Maniatis, T.2
  • 30
    • 0027222103 scopus 로고
    • The oncoprotein Bcl-3 can facilitate NF-κB-mediated transactivation by removing inhibiting p50 homodimers from select κB sites
    • Franzoso, G., V. Bours, V. Azarenko, S. Park, M. Tomita-Yamaguchi, T. Kanno, K. Brown, and U. Siebenlist. 1993. The oncoprotein Bcl-3 can facilitate NF-κB-mediated transactivation by removing inhibiting p50 homodimers from select κB sites. EMBO J. 12:3893.
    • (1993) EMBO J. , vol.12 , pp. 3893
    • Franzoso, G.1    Bours, V.2    Azarenko, V.3    Park, S.4    Tomita-Yamaguchi, M.5    Kanno, T.6    Brown, K.7    Siebenlist, U.8
  • 31
    • 0026758170 scopus 로고
    • The candidate oncoprotein Bcl-3 is an antagonist of p50/ NF-κB-mediated inhibition
    • Franzoso, G., V. Bours, S. Park, M. Tomita-Yamaguchi, K. Kelly, and U. Siebenlist. 1992. The candidate oncoprotein Bcl-3 is an antagonist of p50/ NF-κB-mediated inhibition. Nature 359:339.
    • (1992) Nature , vol.359 , pp. 339
    • Franzoso, G.1    Bours, V.2    Park, S.3    Tomita-Yamaguchi, M.4    Kelly, K.5    Siebenlist, U.6
  • 32
    • 0027446955 scopus 로고
    • The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers
    • Bours, V., G. Franzoso, V. Azarenko, S. Park, T. Kanno, K. Brown, and U. Siebenlist. 1993. The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers. Cell 72:729.
    • (1993) Cell , vol.72 , pp. 729
    • Bours, V.1    Franzoso, G.2    Azarenko, V.3    Park, S.4    Kanno, T.5    Brown, K.6    Siebenlist, U.7
  • 33
    • 0028960452 scopus 로고
    • Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators
    • Schmitz, M. L., G. Stelzer, H. Altmann, M. Meisterernst, and P. A. Baeuerle. 1995. Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators. J. Biol. Chem. 270:7219.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7219
    • Schmitz, M.L.1    Stelzer, G.2    Altmann, H.3    Meisterernst, M.4    Baeuerle, P.A.5
  • 34
    • 0027316201 scopus 로고
    • Functional and physical association between NF-κB and C/EBP family members: A Rel domain-bZip interaction
    • Stein, B., P. C. Cogswell, and A. S. Baldwin, Jr. 1993. Functional and physical association between NF-κB and C/EBP family members: a Rel domain-bZip interaction. Mol. Cell. Biol. 13:3964.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3964
    • Stein, B.1    Cogswell, P.C.2    Baldwin Jr., A.S.3
  • 35
    • 0027224017 scopus 로고
    • Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function
    • Stein, B., A. S. Baldwin, Jr., D. W. Ballard, W. C. Greene, P. Angel, and P. Herrlich. 1993. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 12:3879.
    • (1993) EMBO J. , vol.12 , pp. 3879
    • Stein, B.1    Baldwin Jr., A.S.2    Ballard, D.W.3    Greene, W.C.4    Angel, P.5    Herrlich, P.6
  • 36
    • 0027209915 scopus 로고
    • A cooperative interaction between NF-κB and Sp1 is required for HIV-1 enhancer activation
    • Perkins, N. D., N. L. Edwards, C. S. Duckett, A. B. Agranoff, R. M. Schmid, and G. J. Nabel. 1993. A cooperative interaction between NF-κB and Sp1 is required for HIV-1 enhancer activation. EMBO J. 12:3351.
    • (1993) EMBO J. , vol.12 , pp. 3351
    • Perkins, N.D.1    Edwards, N.L.2    Duckett, C.S.3    Agranoff, A.B.4    Schmid, R.M.5    Nabel, G.J.6
  • 37
    • 0027983512 scopus 로고
    • An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation
    • Perkins, N. D., A. B. Agranoff, E. Pascal, and G. J. Nabel. 1994. An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation. Mol. Cell. Biol. 14:6570.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6570
    • Perkins, N.D.1    Agranoff, A.B.2    Pascal, E.3    Nabel, G.J.4
  • 38
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells
    • Schreck, R., B. Meier, D. N. Manuel, W. Droge, and P. A. Baeuerle. 1992. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med. 175:1181.
    • (1992) J. Exp. Med. , vol.175 , pp. 1181
    • Schreck, R.1    Meier, B.2    Manuel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 39
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1
    • Schreck, R., P. Rieber, and P. A. Baeuerle. 1991. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J. 10:2247.
    • (1991) EMBO J. , vol.10 , pp. 2247
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 40
    • 0028167846 scopus 로고
    • Inhibition of NF-κB by sodium salicylate and aspirin
    • Kopp, E., and S. Ghosh. 1994. Inhibition of NF-κB by sodium salicylate and aspirin. Science 265:956.
    • (1994) Science , vol.265 , pp. 956
    • Kopp, E.1    Ghosh, S.2
  • 41
    • 0027520473 scopus 로고
    • Proteolytic degradation of MAD3 (IκBα) and enhanced processing of the NF-κB precursor p105 are obligatory steps in the activation of NF-κB
    • Mellits, K. H., R. T. Hay, and S. Goodbourn. 1993. Proteolytic degradation of MAD3 (IκBα) and enhanced processing of the NF-κB precursor p105 are obligatory steps in the activation of NF-κB. Nucleic Acids Res. 21:5059.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5059
    • Mellits, K.H.1    Hay, R.T.2    Goodbourn, S.3
  • 42
    • 0027058849 scopus 로고
    • Suppressive effects of E3330, a novel quinone derivative, on tumor necrosis factor-α generation from monocytes and macrophages
    • Miyamoto, K., J. Nagakawa, I. Hishinuma, K. Hirota, M. Yasuda, K. Katayama, and I. Yamatsu. 1992. Suppressive effects of E3330, a novel quinone derivative, on tumor necrosis factor-α generation from monocytes and macrophages. Agents Actions 37:297.
    • (1992) Agents Actions , vol.37 , pp. 297
    • Miyamoto, K.1    Nagakawa, J.2    Hishinuma, I.3    Hirota, K.4    Yasuda, M.5    Katayama, K.6    Yamatsu, I.7
  • 44
    • 0026716456 scopus 로고
    • Protective effects of (2E)-3-[5-(2,3-dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propenoic acid on endotoxin-mediated hepatitis in mice
    • Nagakawa, J., I. Hishinuma, K. Miyamoto, K. Hirota, S. Abe, T. Yamanaka, K. Katayama, and I. Yamatsu. 1992. Protective effects of (2E)-3-[5-(2,3-dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propenoic acid on endotoxin-mediated hepatitis in mice. J. Pharmacol. Exp. Ther. 262:145.
    • (1992) J. Pharmacol. Exp. Ther. , vol.262 , pp. 145
    • Nagakawa, J.1    Hishinuma, I.2    Miyamoto, K.3    Hirota, K.4    Abe, S.5    Yamanaka, T.6    Katayama, K.7    Yamatsu, I.8
  • 45
    • 0025186678 scopus 로고
    • B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor a gene in primary macrophages
    • Shakhov, A. N., M. A. Collart, P. Vassalli, S. A. Nedospasov, and C. V. Jongeneel. 1990. κB-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor a gene in primary macrophages. J. Exp. Med. 171:35.
    • (1990) J. Exp. Med. , vol.171 , pp. 35
    • Shakhov, A.N.1    Collart, M.A.2    Vassalli, P.3    Nedospasov, S.A.4    Jongeneel, C.V.5
  • 46
    • 0025260779 scopus 로고
    • Regulation of tumor necrosis factor alpha transcription in macrophages: Involvement of four κB-like motifs and of constitutive and inducible forms of NF-κB
    • Collart, M. A., P. Baeuerle, and P. Vassalli. 1990. Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four κB-like motifs and of constitutive and inducible forms of NF-κB. Mol. Cell. Biol. 10:1498.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1498
    • Collart, M.A.1    Baeuerle, P.2    Vassalli, P.3
  • 47
    • 0021967217 scopus 로고
    • Trans-activator gene of human T-lymphotropic virus typeIII (HTLV-III)
    • Arya, S. K., C. Guo, S. F. Josephs, and F. Wong-Staal. 1985. trans-activator gene of human T-lymphotropic virus typeIII (HTLV-III). Science 229:69.
    • (1985) Science , vol.229 , pp. 69
    • Arya, S.K.1    Guo, C.2    Josephs, S.F.3    Wong-Staal, F.4
  • 48
    • 0024294357 scopus 로고
    • Activation of DNA binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor
    • Baeuerle, P. A., and D. Baltimore. 1988. Activation of DNA binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 53: 211.
    • (1988) Cell , vol.53 , pp. 211
    • Baeuerle, P.A.1    Baltimore, D.2
  • 49
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNa polymeraseII in a soluble extract from isolated mammalian nuclei
    • Dignam, J. P., R. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymeraseII in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475
    • Dignam, J.P.1    Lebovitz, R.2    Roeder, R.G.3
  • 50
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17:6420.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6420
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 51
    • 0025998840 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    • T. Hunter and B. M. Sefton, eds. Academic Press. Inc., San Diego, CA
    • Boyle, W. J., P. van der Geer, and T. Hunter. 1991. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. In Methods in Enzymology, Vol. 201. T. Hunter and B. M. Sefton, eds. Academic Press. Inc., San Diego, CA, p. 110.
    • (1991) Methods in Enzymology , vol.201 , pp. 110
    • Boyle, W.J.1    Van Der Geer, P.2    Hunter, T.3
  • 53
    • 0027245086 scopus 로고
    • Cytokine-inducible expression in endothelial cells of an IκBα-like gene is regulated by NF-κB
    • de Martin, R., B. Vanhove, Q. Cheng, E. Hofer, V. Csizmadia, H. Winkler, and F. H. Bach. 1993. Cytokine-inducible expression in endothelial cells of an IκBα-like gene is regulated by NF-κB. EMBO J. 12:2773.
    • (1993) EMBO J. , vol.12 , pp. 2773
    • De Martin, R.1    Vanhove, B.2    Cheng, Q.3    Hofer, E.4    Csizmadia, V.5    Winkler, H.6    Bach, F.H.7
  • 54
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: Positive regulation by members of the rel/NF-κB family
    • Le Bail, O., R. Schmidt-Ullrich, and A. Israel. 1993. Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: positive regulation by members of the rel/NF-κB family. EMBO J. 12:5043.
    • (1993) EMBO J. , vol.12 , pp. 5043
    • Le Bail, O.1    Schmidt-Ullrich, R.2    Israel, A.3
  • 56
    • 0026560014 scopus 로고
    • Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system
    • Dressier, K. A., S. Mathias, and R. N. Kolesnick. 1992. Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system. Science 255:1715.
    • (1992) Science , vol.255 , pp. 1715
    • Dressier, K.A.1    Mathias, S.2    Kolesnick, R.N.3
  • 57
    • 0026458406 scopus 로고
    • TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
    • Schutze, S., K. Potthoff, T. Machleidt, D. Berkovic, K. Wiegmann, and M. Kronke. 1992. TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71:765.
    • (1992) Cell , vol.71 , pp. 765
    • Schutze, S.1    Potthoff, K.2    Machleidt, T.3    Berkovic, D.4    Wiegmann, K.5    Kronke, M.6
  • 58
    • 0025889011 scopus 로고
    • Characterization of a ceramide-activated protein kinase: Stimulation by tumor necrosis factor α
    • Mathias, S., K. A. Dressier, and R. N. Kolesnick. 1991. Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor α. Proc. Natl. Acad. Sci. USA 88:10009.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10009
    • Mathias, S.1    Dressier, K.A.2    Kolesnick, R.N.3
  • 59
    • 0027197994 scopus 로고
    • Substrate recognition by ceramide-activated protein kinase: Evidence that kinase activity is proline-directed
    • Joseph, C. K., H. S. Byun, R. Bittman, and R. N. Kolesnick. 1993. Substrate recognition by ceramide-activated protein kinase: evidence that kinase activity is proline-directed. J. Biol. Chem. 268:20002.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20002
    • Joseph, C.K.1    Byun, H.S.2    Bittman, R.3    Kolesnick, R.N.4
  • 60
    • 0025267782 scopus 로고
    • Protein kinase C-independent activation of nuclear factor κB by tumor necrosis factor
    • Meichle, A., S. Schutze, G. Hensel, D. Brunsing, and M. Kronke. 1990. Protein kinase C-independent activation of nuclear factor κB by tumor necrosis factor. J. Biol. Chem. 265:8339.
    • (1990) J. Biol. Chem. , vol.265 , pp. 8339
    • Meichle, A.1    Schutze, S.2    Hensel, G.3    Brunsing, D.4    Kronke, M.5
  • 62
    • 0028986075 scopus 로고
    • Control of IκBα proteolysis by site-specific, signal induced phosphorylation
    • Brown, K., S. Gerstberger, L. Carlson, G. Franzoso, and U. Siebenlist. 1995. Control of IκBα proteolysis by site-specific, signal induced phosphorylation. Science 267:1485.
    • (1995) Science , vol.267 , pp. 1485
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 63
    • 0028978032 scopus 로고
    • Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli
    • Traenckner, E. B. M., H. L. Pahl, T. Henkel, K. N. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:2876.
    • (1995) EMBO J. , vol.14 , pp. 2876
    • Traenckner, E.B.M.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 64
    • 0029122799 scopus 로고
    • N- And C-terminal sequences control degradation of MAD3/IκBα in response to inducers of NF-κB activity
    • Whiteside, S. T., M. K. Ernst, O. LeBail, C. Laurent-Winter, N. Rice, and A. Israel. 1995. N-and C-terminal sequences control degradation of MAD3/IκBα in response to inducers of NF-κB activity. Mol. Cell. Biol. 15:5339.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5339
    • Whiteside, S.T.1    Ernst, M.K.2    Lebail, O.3    Laurent-Winter, C.4    Rice, N.5    Israel, A.6
  • 66
    • 0028986111 scopus 로고
    • Inducible degradation of IκBα in vitro and in vivo requires the acidic C-terminal domain of the protein
    • Rodriguez, M. S., I. Michalopoulos, F. Arenzana-Seisdedos, and R. T. Hay. 1995. Inducible degradation of IκBα in vitro and in vivo requires the acidic C-terminal domain of the protein. Mol. Cell. Biol. 15:2413.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2413
    • Rodriguez, M.S.1    Michalopoulos, I.2    Arenzana-Seisdedos, F.3    Hay, R.T.4
  • 68
    • 0028847308 scopus 로고
    • Potentiation of glucocorticoid-mediated gene expression by the novel benzoquinone derivative (2E)-3-[5-(2,3-dimethoxy-o-methyl-1,4-benzoqumoyl)]-2-nonyl-2-propenoic acid (E3330)
    • Tanaka, H., Y. Makino, M. Hiramoto, H. Handa, I. Makino. 1995. Potentiation of glucocorticoid-mediated gene expression by the novel benzoquinone derivative (2E)-3-[5-(2,3-dimethoxy-o-methyl-1,4-benzoqumoyl)]-2-nonyl-2-propenoic acid (E3330). Eur. J. Pharmacol. 291:121.
    • (1995) Eur. J. Pharmacol. , vol.291 , pp. 121
    • Tanaka, H.1    Makino, Y.2    Hiramoto, M.3    Handa, H.4    Makino, I.5


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