메뉴 건너뛰기




Volumn 71, Issue , 2014, Pages 411-449

Aging, the metabolic syndrome, and ischemic stroke: Redefining the approach for studying the blood-brain barrier in a complex neurological disease

Author keywords

Comorbidity; Diabetes; Hypertension; Middle cerebral artery occlusion; Neurovascular unit

Indexed keywords

3 NITROTYROSINE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CALCIUM ION; CATALASE; CLAUDIN 5; COLLAGEN; CYTOCHROME C; CYTOKINE; ENDONUCLEASE; FREE RADICAL; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOCORTICOID; GLUTAMIC ACID; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OCCLUDIN; PHOSPHOLIPASE; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE; TIGHT JUNCTION PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84907979170     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/bs.apha.2014.07.001     Document Type: Chapter
Times cited : (37)

References (211)
  • 2
    • 83655190693 scopus 로고    scopus 로고
    • Comparison of annular diffusion denuder and high volume air samplers for measuring per- and polyfluoroalkyl substances in the atmosphere
    • Ahrens L., Shoeib M., Harner T., Lane D.A., Guo R., Reiner E.J. Comparison of annular diffusion denuder and high volume air samplers for measuring per- and polyfluoroalkyl substances in the atmosphere. Analytical Chemistry 2011, 83(24):9622-9628. 10.1021/ac202414w.
    • (2011) Analytical Chemistry , vol.83 , Issue.24 , pp. 9622-9628
    • Ahrens, L.1    Shoeib, M.2    Harner, T.3    Lane, D.A.4    Guo, R.5    Reiner, E.J.6
  • 3
    • 79957994598 scopus 로고    scopus 로고
    • Secondary prevention of stroke in the elderly: A review of the evidence
    • Alhusban A., Fagan S.C. Secondary prevention of stroke in the elderly: A review of the evidence. The American Journal of Geriatric Pharmacotherapy 2011, 9(3):143-152. 10.1016/j.amjopharm.2011.04.002.
    • (2011) The American Journal of Geriatric Pharmacotherapy , vol.9 , Issue.3 , pp. 143-152
    • Alhusban, A.1    Fagan, S.C.2
  • 5
    • 42449124483 scopus 로고    scopus 로고
    • Diabetes-, stress- and ageing-related changes in synaptic plasticity in hippocampus and neocortex-The same metaplastic process?
    • Artola A. Diabetes-, stress- and ageing-related changes in synaptic plasticity in hippocampus and neocortex-The same metaplastic process?. European Journal of Pharmacology 2008, 585(1):153-162. 10.1016/j.ejphar.2007.11.084.
    • (2008) European Journal of Pharmacology , vol.585 , Issue.1 , pp. 153-162
    • Artola, A.1
  • 6
    • 80052155763 scopus 로고    scopus 로고
    • Characteristics of first ever ischemic stroke in the very elderly: Profile of vascular risk factors and clinical outcome
    • Auriel E., Gur A.Y., Uralev O., Brill S., Shopin L., Karni A., et al. Characteristics of first ever ischemic stroke in the very elderly: Profile of vascular risk factors and clinical outcome. Clinical Neurology and Neurosurgery 2011, 113(8):654-657. 10.1016/j.clineuro.2011.05.011.
    • (2011) Clinical Neurology and Neurosurgery , vol.113 , Issue.8 , pp. 654-657
    • Auriel, E.1    Gur, A.Y.2    Uralev, O.3    Brill, S.4    Shopin, L.5    Karni, A.6
  • 7
    • 0038016402 scopus 로고    scopus 로고
    • Accelerated glial reactivity to stroke in aged rats correlates with reduced functional recovery
    • Badan I., Buchhold B., Hamm A., Gratz M., Walker L.C., Platt D., et al. Accelerated glial reactivity to stroke in aged rats correlates with reduced functional recovery. Journal of Cerebral Blood Flow and Metabolism 2003, 23(7):845-854. 10.1097/01.WCB.0000071883.63724.A7.
    • (2003) Journal of Cerebral Blood Flow and Metabolism , vol.23 , Issue.7 , pp. 845-854
    • Badan, I.1    Buchhold, B.2    Hamm, A.3    Gratz, M.4    Walker, L.C.5    Platt, D.6
  • 8
    • 84883028911 scopus 로고    scopus 로고
    • Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: A paracrine mechanism contributing to vascular redox dysregulation and inflammation
    • Epub 2012 Dec 3
    • Bailey-Downs L.C., Tucsek Z., Toth P., Sosnowska D., Gautam T., Sonntag W.E., et al. Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: A paracrine mechanism contributing to vascular redox dysregulation and inflammation. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2013, 68(7):780-792. Epub 2012 Dec 3. 10.1093/gerona/gls238.
    • (2013) The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences , vol.68 , Issue.7 , pp. 780-792
    • Bailey-Downs, L.C.1    Tucsek, Z.2    Toth, P.3    Sosnowska, D.4    Gautam, T.5    Sonntag, W.E.6
  • 9
    • 79956002775 scopus 로고    scopus 로고
    • Increased adult neurogenesis in the subventricular zone in a rat model of sepsis
    • Bakirci S., Kafa I.M., Uysal M., Ayberk Kurt M. Increased adult neurogenesis in the subventricular zone in a rat model of sepsis. Neuroscience Letters 2011, 497(1):27-31. 10.1016/j.neulet.2011.04.014.
    • (2011) Neuroscience Letters , vol.497 , Issue.1 , pp. 27-31
    • Bakirci, S.1    Kafa, I.M.2    Uysal, M.3    Ayberk Kurt, M.4
  • 10
    • 70049084419 scopus 로고    scopus 로고
    • Blood-brain barrier P-glycoprotein function decreases in specific brain regions with aging: A possible role in progressive neurodegeneration
    • Bartels A.L., Kortekaas R., Bart J., Willemsen A.T., de Klerk O.L., de Vries J.J., et al. Blood-brain barrier P-glycoprotein function decreases in specific brain regions with aging: A possible role in progressive neurodegeneration. Neurobiology of Aging 2009, 30(11):1818-1824. 10.1016/j.neurobiolaging.2008.02.002.
    • (2009) Neurobiology of Aging , vol.30 , Issue.11 , pp. 1818-1824
    • Bartels, A.L.1    Kortekaas, R.2    Bart, J.3    Willemsen, A.T.4    de Klerk, O.L.5    de Vries, J.J.6
  • 11
    • 84866436856 scopus 로고    scopus 로고
    • The age-related increase in low-grade systemic inflammation (inflamm-aging) is not driven by cytomegalovirus infection
    • Bartlett D.B., Firth C.M., Phillips A.C., Moss P., Baylis D., Syddall H., et al. The age-related increase in low-grade systemic inflammation (inflamm-aging) is not driven by cytomegalovirus infection. Aging Cell 2012, 11(5):912-915. 10.1111/j.1474-9726.2012.00849.x.
    • (2012) Aging Cell , vol.11 , Issue.5 , pp. 912-915
    • Bartlett, D.B.1    Firth, C.M.2    Phillips, A.C.3    Moss, P.4    Baylis, D.5    Syddall, H.6
  • 12
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • 87/1/245 [pii]
    • Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiological Reviews 2007, 87(1):245-313. 87/1/245 [pii]. 10.1152/physrev.00044.2005.
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 13
    • 84866316014 scopus 로고    scopus 로고
    • Astrocyte senescence as a component of Alzheimer's disease
    • Bhat R., Crowe E.P., Bitto A., Moh M., Katsetos C.D., Garcia F.U., et al. Astrocyte senescence as a component of Alzheimer's disease. PLoS One 2012, 7(9):e45069. 10.1371/journal.pone.0045069.
    • (2012) PLoS One , vol.7 , Issue.9 , pp. e45069
    • Bhat, R.1    Crowe, E.P.2    Bitto, A.3    Moh, M.4    Katsetos, C.D.5    Garcia, F.U.6
  • 15
    • 79954941363 scopus 로고    scopus 로고
    • How cytokines leave their mark: The role of the placenta in developmental programming of brain and behavior
    • Bilbo S.D. How cytokines leave their mark: The role of the placenta in developmental programming of brain and behavior. Brain, Behavior, and Immunity 2011, 25(4):602-603. 10.1016/j.bbi.2011.01.018.
    • (2011) Brain, Behavior, and Immunity , vol.25 , Issue.4 , pp. 602-603
    • Bilbo, S.D.1
  • 17
    • 13844281550 scopus 로고    scopus 로고
    • How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: The role of microglia and astrocytes
    • Blasko I., Stampfer-Kountchev M., Robatscher P., Veerhuis R., Eikelenboom P., Grubeck-Loebenstein B. How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: The role of microglia and astrocytes. Aging Cell 2004, 3(4):169-176. 10.1111/j.1474-9728.2004.00101.x.
    • (2004) Aging Cell , vol.3 , Issue.4 , pp. 169-176
    • Blasko, I.1    Stampfer-Kountchev, M.2    Robatscher, P.3    Veerhuis, R.4    Eikelenboom, P.5    Grubeck-Loebenstein, B.6
  • 18
    • 38149012414 scopus 로고    scopus 로고
    • Metabolic syndrome and ischemic stroke risk: Northern Manhattan study
    • STROKEAHA.107.496588 [pii]
    • Boden-Albala B., Sacco R.L., Lee H.S., Grahame-Clarke C., Rundek T., Elkind M.V., et al. Metabolic syndrome and ischemic stroke risk: Northern Manhattan study. Stroke 2008, 39(1):30-35. STROKEAHA.107.496588 [pii]. 10.1161/STROKEAHA.107.496588.
    • (2008) Stroke , vol.39 , Issue.1 , pp. 30-35
    • Boden-Albala, B.1    Sacco, R.L.2    Lee, H.S.3    Grahame-Clarke, C.4    Rundek, T.5    Elkind, M.V.6
  • 19
    • 84884544176 scopus 로고    scopus 로고
    • DNA modifications in atherosclerosis: From the past to the future
    • Borghini A., Cervelli T., Galli A., Andreassi M.G. DNA modifications in atherosclerosis: From the past to the future. Atherosclerosis 2013, 230(2):202-209. 10.1016/j.atherosclerosis.2013.07.038.
    • (2013) Atherosclerosis , vol.230 , Issue.2 , pp. 202-209
    • Borghini, A.1    Cervelli, T.2    Galli, A.3    Andreassi, M.G.4
  • 20
    • 53049098182 scopus 로고    scopus 로고
    • Neurogenesis in the adult brain: From bench to bedside?
    • Brandt M.D., Storch A. Neurogenesis in the adult brain: From bench to bedside?. Fortschritte der Neurologie-Psychiatrie 2008, 76(9):517-529. 10.1055/s-2008-1038218.
    • (2008) Fortschritte der Neurologie-Psychiatrie , vol.76 , Issue.9 , pp. 517-529
    • Brandt, M.D.1    Storch, A.2
  • 21
    • 0033830240 scopus 로고    scopus 로고
    • Beta-amyloid peptides are cytotoxic to astrocytes in culture: A role for oxidative stress
    • Brera B., Serrano A., de Ceballos M.L. Beta-amyloid peptides are cytotoxic to astrocytes in culture: A role for oxidative stress. Neurobiology of Disease 2000, 7(4):395-405. 10.1006/nbdi.2000.0313.
    • (2000) Neurobiology of Disease , vol.7 , Issue.4 , pp. 395-405
    • Brera, B.1    Serrano, A.2    de Ceballos, M.L.3
  • 22
    • 84866544628 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response in aging and age-related diseases
    • Brown M.K., Naidoo N. The endoplasmic reticulum stress response in aging and age-related diseases. Frontiers in Physiology 2012, 3:263. 10.3389/fphys.2012.00263.
    • (2012) Frontiers in Physiology , vol.3 , pp. 263
    • Brown, M.K.1    Naidoo, N.2
  • 23
    • 79960671469 scopus 로고    scopus 로고
    • Age related macular degeneration and drusen: Neuroinflammation in the retina
    • Buschini E., Piras A., Nuzzi R., Vercelli A. Age related macular degeneration and drusen: Neuroinflammation in the retina. Progress in Neurobiology 2011, 95(1):14-25. 10.1016/j.pneurobio.2011.05.011.
    • (2011) Progress in Neurobiology , vol.95 , Issue.1 , pp. 14-25
    • Buschini, E.1    Piras, A.2    Nuzzi, R.3    Vercelli, A.4
  • 24
    • 84871650203 scopus 로고    scopus 로고
    • Neuroinflammation and neurodegeneration in overnutrition-induced diseases
    • Cai D. Neuroinflammation and neurodegeneration in overnutrition-induced diseases. Trends in Endocrinology and Metabolism 2013, 24(1):40-47. S1043-2760(12)00203-2 [pii]. 10.1016/j.tem.2012.11.003.
    • (2013) Trends in Endocrinology and Metabolism , vol.24 , Issue.1 , pp. 40-47
    • Cai, D.1
  • 25
    • 84882761023 scopus 로고    scopus 로고
    • Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder
    • cia-8-1089 [pii]
    • Cai Z., Yan Y., Wang Y. Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder. Clinical Interventions in Aging 2013, 8:1089-1095. cia-8-1089 [pii]. 10.2147/CIA.S46536.
    • (2013) Clinical Interventions in Aging , vol.8 , pp. 1089-1095
    • Cai, Z.1    Yan, Y.2    Wang, Y.3
  • 26
    • 84885669865 scopus 로고    scopus 로고
    • Shared and non-shared familial susceptibility of coronary heart disease, ischemic stroke, peripheral artery disease and aortic disease
    • Calling S., Ji J., Sundquist J., Sundquist K., Zoller B. Shared and non-shared familial susceptibility of coronary heart disease, ischemic stroke, peripheral artery disease and aortic disease. International Journal of Cardiology 2013, 168(3):2844-2850. 10.1016/j.ijcard.2013.03.149.
    • (2013) International Journal of Cardiology , vol.168 , Issue.3 , pp. 2844-2850
    • Calling, S.1    Ji, J.2    Sundquist, J.3    Sundquist, K.4    Zoller, B.5
  • 27
    • 79960623937 scopus 로고    scopus 로고
    • Decreased myeloperoxidase expressing cells in the aged rat brain after excitotoxic damage
    • Campuzano O., Castillo-Ruiz M.M., Acarin L., Gonzalez B., Castellano B. Decreased myeloperoxidase expressing cells in the aged rat brain after excitotoxic damage. Experimental Gerontology 2011, 46(9):723-730. 10.1016/j.exger.2011.05.003.
    • (2011) Experimental Gerontology , vol.46 , Issue.9 , pp. 723-730
    • Campuzano, O.1    Castillo-Ruiz, M.M.2    Acarin, L.3    Gonzalez, B.4    Castellano, B.5
  • 30
    • 84904679767 scopus 로고    scopus 로고
    • The influences of obesity and age on functional performance during intermittent upper extremity tasks
    • Cavuoto L.A., Nussbaum M.A. The influences of obesity and age on functional performance during intermittent upper extremity tasks. Journal of Occupational and Environmental Hygiene 2014, 10.1080/15459624.2014.887848.
    • (2014) Journal of Occupational and Environmental Hygiene
    • Cavuoto, L.A.1    Nussbaum, M.A.2
  • 31
    • 84866491240 scopus 로고    scopus 로고
    • The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus
    • Cerbai F., Lana D., Nosi D., Petkova-Kirova P., Zecchi S., Brothers H.M., et al. The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus. PLoS One 2012, 7(9):e45250. 10.1371/journal.pone.0045250.
    • (2012) PLoS One , vol.7 , Issue.9 , pp. e45250
    • Cerbai, F.1    Lana, D.2    Nosi, D.3    Petkova-Kirova, P.4    Zecchi, S.5    Brothers, H.M.6
  • 32
    • 79951812254 scopus 로고    scopus 로고
    • Pathophysiological response to experimental diffuse brain trauma differs as a function of developmental age
    • Cernak I., Chang T., Ahmed F.A., Cruz M.I., Vink R., Stoica B., et al. Pathophysiological response to experimental diffuse brain trauma differs as a function of developmental age. Developmental Neuroscience 2010, 32(5-6):442-453. 10.1159/000320085.
    • (2010) Developmental Neuroscience , vol.32 , Issue.5-6 , pp. 442-453
    • Cernak, I.1    Chang, T.2    Ahmed, F.A.3    Cruz, M.I.4    Vink, R.5    Stoica, B.6
  • 33
    • 0033198777 scopus 로고    scopus 로고
    • Activation of A(1) adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100beta protein from cultured astrocytes
    • Ciccarelli R., Di Iorio P., Bruno V., Battaglia G., D'Alimonte I., D'Onofrio M., et al. Activation of A(1) adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100beta protein from cultured astrocytes. Glia 1999, 27(3):275-281.
    • (1999) Glia , vol.27 , Issue.3 , pp. 275-281
    • Ciccarelli, R.1    Di Iorio, P.2    Bruno, V.3    Battaglia, G.4    D'Alimonte, I.5    D'Onofrio, M.6
  • 34
    • 70349958031 scopus 로고    scopus 로고
    • The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease
    • Ciesielska A., Joniec I., Kurkowska-Jastrzebska I., Cudna A., Przybylkowski A., Czlonkowska A., et al. The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease. Inflammation Research 2009, 58(11):747-753. 10.1007/s00011-009-0026-6.
    • (2009) Inflammation Research , vol.58 , Issue.11 , pp. 747-753
    • Ciesielska, A.1    Joniec, I.2    Kurkowska-Jastrzebska, I.3    Cudna, A.4    Przybylkowski, A.5    Czlonkowska, A.6
  • 35
    • 84865339274 scopus 로고    scopus 로고
    • Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions
    • Clarner T., Diederichs F., Berger K., Denecke B., Gan L., van der Valk P., et al. Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions. Glia 2012, 60(10):1468-1480. 10.1002/glia.22367.
    • (2012) Glia , vol.60 , Issue.10 , pp. 1468-1480
    • Clarner, T.1    Diederichs, F.2    Berger, K.3    Denecke, B.4    Gan, L.5    van der Valk, P.6
  • 36
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    • 35097565 [pii]
    • Cleveland D.W., Rothstein J.D. From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS. Nature Reviews. Neuroscience 2001, 2(11):806-819. 35097565 [pii]. 10.1038/35097565.
    • (2001) Nature Reviews. Neuroscience , vol.2 , Issue.11 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 37
    • 84863700073 scopus 로고    scopus 로고
    • Influence of age on the association between lifestyle factors and risk of hypertension
    • Cohen L., Curhan G.C., Forman J.P. Influence of age on the association between lifestyle factors and risk of hypertension. Journal of the American Society of Hypertension 2012, 6(4):284-290. 10.1016/j.jash.2012.06.002.
    • (2012) Journal of the American Society of Hypertension , vol.6 , Issue.4 , pp. 284-290
    • Cohen, L.1    Curhan, G.C.2    Forman, J.P.3
  • 38
    • 22244442489 scopus 로고    scopus 로고
    • The biochemistry of Parkinson's disease
    • Cookson M.R. The biochemistry of Parkinson's disease. Annual Review of Biochemistry 2005, 74:29-52. 10.1146/annurev.biochem.74.082803.133400.
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 29-52
    • Cookson, M.R.1
  • 39
    • 39849100913 scopus 로고    scopus 로고
    • Ageing and atherosclerosis: Mechanisms and therapeutic options
    • Costopoulos C., Liew T.V., Bennett M. Ageing and atherosclerosis: Mechanisms and therapeutic options. Biochemical Pharmacology 2008, 75(6):1251-1261. 10.1016/j.bcp.2007.10.006.
    • (2008) Biochemical Pharmacology , vol.75 , Issue.6 , pp. 1251-1261
    • Costopoulos, C.1    Liew, T.V.2    Bennett, M.3
  • 41
    • 84885638846 scopus 로고    scopus 로고
    • The "know your numbers" program in Atahualpa-a pilot study aimed to reduce cardiovascular diseases and stroke burden in rural communities of developing countries
    • Del Brutto O.H., Montalvan M., Tettamanti D., Penaherrera E., Santibanez R., Pow-Chon-Long F., et al. The "know your numbers" program in Atahualpa-a pilot study aimed to reduce cardiovascular diseases and stroke burden in rural communities of developing countries. International Journal of Cardiology 2013, 168(3):3123-3124. 10.1016/j.ijcard.2013.04.049.
    • (2013) International Journal of Cardiology , vol.168 , Issue.3 , pp. 3123-3124
    • Del Brutto, O.H.1    Montalvan, M.2    Tettamanti, D.3    Penaherrera, E.4    Santibanez, R.5    Pow-Chon-Long, F.6
  • 42
    • 84889089284 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome and its correlation with the cardiovascular health status in stroke- and ischemic heart disease-free Ecuadorian natives/mestizos aged >/=40 years living in Atahualpa: A population-based study
    • Del Brutto O.H., Zambrano M., Penaherrera E., Montalvan M., Pow-Chon-Long F., Tettamanti D. Prevalence of the metabolic syndrome and its correlation with the cardiovascular health status in stroke- and ischemic heart disease-free Ecuadorian natives/mestizos aged >/=40 years living in Atahualpa: A population-based study. Diabetes & Metabolic Syndrome 2013, 7(4):218-222. 10.1016/j.dsx.2013.10.006.
    • (2013) Diabetes & Metabolic Syndrome , vol.7 , Issue.4 , pp. 218-222
    • Del Brutto, O.H.1    Zambrano, M.2    Penaherrera, E.3    Montalvan, M.4    Pow-Chon-Long, F.5    Tettamanti, D.6
  • 43
    • 84889647736 scopus 로고    scopus 로고
    • Impact of gender-age interaction on the outcome of ischemic stroke in an Italian cohort of patients treated according to a standardized clinical pathway
    • Denti L., Artoni A., Scoditti U., Caminiti C., Giambanco F., Casella M., et al. Impact of gender-age interaction on the outcome of ischemic stroke in an Italian cohort of patients treated according to a standardized clinical pathway. European Journal of Internal Medicine 2013, 24(8):807-812. 10.1016/j.ejim.2013.07.015.
    • (2013) European Journal of Internal Medicine , vol.24 , Issue.8 , pp. 807-812
    • Denti, L.1    Artoni, A.2    Scoditti, U.3    Caminiti, C.4    Giambanco, F.5    Casella, M.6
  • 44
    • 84862062536 scopus 로고    scopus 로고
    • Inflammation, oxidative stress, and the metabolic syndrome
    • Devaraj S., Goyal R., Jialal I. Inflammation, oxidative stress, and the metabolic syndrome. US Endocrinology 2008, 4(2):32-37.
    • (2008) US Endocrinology , vol.4 , Issue.2 , pp. 32-37
    • Devaraj, S.1    Goyal, R.2    Jialal, I.3
  • 46
    • 0347294707 scopus 로고    scopus 로고
    • NMDA receptor subunits are modified transcriptionally and post-translationally in the brain of streptozotocin-diabetic rats
    • Di Luca M., Ruts L., Gardoni F., Cattabeni F., Biessels G.J., Gispen W.H. NMDA receptor subunits are modified transcriptionally and post-translationally in the brain of streptozotocin-diabetic rats. Diabetologia 1999, 42(6):693-701. 10.1007/s001250051217.
    • (1999) Diabetologia , vol.42 , Issue.6 , pp. 693-701
    • Di Luca, M.1    Ruts, L.2    Gardoni, F.3    Cattabeni, F.4    Biessels, G.J.5    Gispen, W.H.6
  • 47
    • 77956184903 scopus 로고    scopus 로고
    • Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat
    • Dinapoli V.A., Benkovic S.A., Li X., Kelly K.A., Miller D.B., Rosen C.L., et al. Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat. Neuroscience 2010, 170(2):633-644. 10.1016/j.neuroscience.2010.07.011.
    • (2010) Neuroscience , vol.170 , Issue.2 , pp. 633-644
    • Dinapoli, V.A.1    Benkovic, S.A.2    Li, X.3    Kelly, K.A.4    Miller, D.B.5    Rosen, C.L.6
  • 48
    • 33744527080 scopus 로고    scopus 로고
    • Selective MCA occlusion: A precise embolic stroke model
    • Dinapoli V.A., Rosen C.L., Nagamine T., Crocco T. Selective MCA occlusion: A precise embolic stroke model. Journal of Neuroscience Methods 2006, 154(1-2):233-238. S0165-0270(06)00007-0 [pii]. 10.1016/j.jneumeth.2005.12.026.
    • (2006) Journal of Neuroscience Methods , vol.154 , Issue.1-2 , pp. 233-238
    • Dinapoli, V.A.1    Rosen, C.L.2    Nagamine, T.3    Crocco, T.4
  • 49
    • 84893821031 scopus 로고    scopus 로고
    • Disability status as an antecedent to chronic conditions: National health interview survey, 2006-2012
    • Dixon-Ibarra A., Horner-Johnson W. Disability status as an antecedent to chronic conditions: National health interview survey, 2006-2012. Preventing Chronic Disease 2014, 11:E15. 10.5888/pcd11.130251.
    • (2014) Preventing Chronic Disease , vol.11 , pp. E15
    • Dixon-Ibarra, A.1    Horner-Johnson, W.2
  • 51
    • 84890127591 scopus 로고    scopus 로고
    • Neutrophils and stroke-Can neutrophils mitigate disease in the central nervous system?
    • Easton A.S. Neutrophils and stroke-Can neutrophils mitigate disease in the central nervous system?. International Immunopharmacology 2013, 17(4):1218-1225. 10.1016/j.intimp.2013.06.015.
    • (2013) International Immunopharmacology , vol.17 , Issue.4 , pp. 1218-1225
    • Easton, A.S.1
  • 52
    • 84870546420 scopus 로고    scopus 로고
    • Age-dependent deficits in fear learning in heterozygous BDNF knock-out mice
    • Endres T., Lessmann V. Age-dependent deficits in fear learning in heterozygous BDNF knock-out mice. Learning & Memory 2012, 19(12):561-570. 10.1101/lm.028068.112.
    • (2012) Learning & Memory , vol.19 , Issue.12 , pp. 561-570
    • Endres, T.1    Lessmann, V.2
  • 53
    • 0020597972 scopus 로고
    • Astrocyte cell lineage. II. Mouse fibrous astrocytes and reactive astrocytes in cultures have vimentin- and GFP-containing intermediate filaments
    • Fedoroff S., White R., Neal J., Subrahmanyan L., Kalnins V.I. Astrocyte cell lineage. II. Mouse fibrous astrocytes and reactive astrocytes in cultures have vimentin- and GFP-containing intermediate filaments. Brain Research 1983, 283(2-3):303-315.
    • (1983) Brain Research , vol.283 , Issue.2-3 , pp. 303-315
    • Fedoroff, S.1    White, R.2    Neal, J.3    Subrahmanyan, L.4    Kalnins, V.I.5
  • 54
    • 84896097922 scopus 로고    scopus 로고
    • Early treatment of hypertension in acute ischemic and intracerebral hemorrhagic stroke: Progress achieved, challenges, and perspectives
    • Feldstein C.A. Early treatment of hypertension in acute ischemic and intracerebral hemorrhagic stroke: Progress achieved, challenges, and perspectives. Journal of the American Society of Hypertension 2013, 10.1016/j.jash.2013.09.004.
    • (2013) Journal of the American Society of Hypertension
    • Feldstein, C.A.1
  • 55
    • 70949100121 scopus 로고    scopus 로고
    • Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis
    • Ferron S.R., Marques-Torrejon M.A., Mira H., Flores I., Taylor K., Blasco M.A., et al. Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis. The Journal of Neuroscience 2009, 29(46):14394-14407. 10.1523/JNEUROSCI.3836-09.2009.
    • (2009) The Journal of Neuroscience , vol.29 , Issue.46 , pp. 14394-14407
    • Ferron, S.R.1    Marques-Torrejon, M.A.2    Mira, H.3    Flores, I.4    Taylor, K.5    Blasco, M.A.6
  • 56
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408(6809):239-247. 10.1038/35041687.
    • (2000) Nature , vol.408 , Issue.6809 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 57
    • 84875874338 scopus 로고    scopus 로고
    • Cognitive interventions targeting brain plasticity in the prodromal and early phases of schizophrenia
    • Fisher M., Loewy R., Hardy K., Schlosser D., Vinogradov S. Cognitive interventions targeting brain plasticity in the prodromal and early phases of schizophrenia. Annual Review of Clinical Psychology 2013, 9:435-463. 10.1146/annurev-clinpsy-032511-143134.
    • (2013) Annual Review of Clinical Psychology , vol.9 , pp. 435-463
    • Fisher, M.1    Loewy, R.2    Hardy, K.3    Schlosser, D.4    Vinogradov, S.5
  • 58
    • 0036751954 scopus 로고    scopus 로고
    • Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases
    • Floyd R.A., Hensley K. Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiology of Aging 2002, 23(5):795-807. S0197458002000192 [pii].
    • (2002) Neurobiology of Aging , vol.23 , Issue.5 , pp. 795-807
    • Floyd, R.A.1    Hensley, K.2
  • 59
    • 79953858141 scopus 로고    scopus 로고
    • Community prevalence of ideal cardiovascular health, by the American Heart Association definition, and relationship with cardiovascular disease incidence
    • Folsom A.R., Yatsuya H., Nettleton J.A., Lutsey P.L., Cushman M., Rosamond W.D., et al. Community prevalence of ideal cardiovascular health, by the American Heart Association definition, and relationship with cardiovascular disease incidence. Journal of the American College of Cardiology 2011, 57(16):1690-1696. 10.1016/j.jacc.2010.11.041.
    • (2011) Journal of the American College of Cardiology , vol.57 , Issue.16 , pp. 1690-1696
    • Folsom, A.R.1    Yatsuya, H.2    Nettleton, J.A.3    Lutsey, P.L.4    Cushman, M.5    Rosamond, W.D.6
  • 60
    • 80051578563 scopus 로고    scopus 로고
    • Treatment with rtPA of stroke associated with intravenous immunoglobulins perfusion
    • Fonseca A.C., Geraldes R., Almeida V., Pinhoe Melo T. Treatment with rtPA of stroke associated with intravenous immunoglobulins perfusion. Journal of Neurological Science 2011, 308(1-2):180-181. 10.1016/j.jns.2011.05.037.
    • (2011) Journal of Neurological Science , vol.308 , Issue.1-2 , pp. 180-181
    • Fonseca, A.C.1    Geraldes, R.2    Almeida, V.3    Pinhoe Melo, T.4
  • 61
    • 33644768153 scopus 로고    scopus 로고
    • Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome
    • 55/1/209 [pii]
    • Fortuno A., San Jose G., Moreno M.U., Beloqui O., Diez J., Zalba G. Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome. Diabetes 2006, 55(1):209-215. 55/1/209 [pii].
    • (2006) Diabetes , vol.55 , Issue.1 , pp. 209-215
    • Fortuno, A.1    San Jose, G.2    Moreno, M.U.3    Beloqui, O.4    Diez, J.5    Zalba, G.6
  • 62
    • 39649085837 scopus 로고    scopus 로고
    • Inflamm-aging as a major characteristic of old people: Can it be prevented or cured?
    • Franceschi C. Inflamm-aging as a major characteristic of old people: Can it be prevented or cured?. Nutrition Reviews 2007, 65(12 Pt. 2):S173-S176.
    • (2007) Nutrition Reviews , vol.65 , Issue.12 , pp. S173-S176
    • Franceschi, C.1
  • 63
    • 33846111415 scopus 로고    scopus 로고
    • Inflamm-aging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
    • Franceschi C., Capri M., Monti D., Giunta S., Olivieri F., Sevini F., et al. Inflamm-aging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans. Mechanisms of Ageing and Development 2007, 128(1):92-105. 10.1016/j.mad.2006.11.016.
    • (2007) Mechanisms of Ageing and Development , vol.128 , Issue.1 , pp. 92-105
    • Franceschi, C.1    Capri, M.2    Monti, D.3    Giunta, S.4    Olivieri, F.5    Sevini, F.6
  • 64
    • 33750221963 scopus 로고    scopus 로고
    • The unfolded protein response is an important regulator of inflammatory genes in endothelial cells
    • 01.ATV.0000242903.41158.a1 [pii]
    • Gargalovic P.S., Gharavi N.M., Clark M.J., Pagnon J., Yang W.P., He A., et al. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology 2006, 26(11):2490-2496. 01.ATV.0000242903.41158.a1 [pii]. 10.1161/01.ATV.0000242903.41158.a1.
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.11 , pp. 2490-2496
    • Gargalovic, P.S.1    Gharavi, N.M.2    Clark, M.J.3    Pagnon, J.4    Yang, W.P.5    He, A.6
  • 66
    • 79953104678 scopus 로고    scopus 로고
    • Outcome after acute ischemic stroke (AIS) in older patients: Effects of age, neurological deficit severity and blood pressure (BP) variations
    • Giantin V., Semplicini A., Franchin A., Simonato M., Baccaglini K., Attanasio F., et al. Outcome after acute ischemic stroke (AIS) in older patients: Effects of age, neurological deficit severity and blood pressure (BP) variations. Archives of Gerontology and Geriatrics 2011, 52(3):e185-e191. 10.1016/j.archger.2010.11.002.
    • (2011) Archives of Gerontology and Geriatrics , vol.52 , Issue.3 , pp. e185-e191
    • Giantin, V.1    Semplicini, A.2    Franchin, A.3    Simonato, M.4    Baccaglini, K.5    Attanasio, F.6
  • 67
    • 84940582076 scopus 로고    scopus 로고
    • Laparoscopic sleeve gastrectomy: Review of 500 cases in single surgeon Australian practice
    • Gibson S.C., Le Page P.A., Taylor C.J. Laparoscopic sleeve gastrectomy: Review of 500 cases in single surgeon Australian practice. ANZ Journal of Surgery 2013, 10.1111/ans.12483.
    • (2013) ANZ Journal of Surgery
    • Gibson, S.C.1    Le Page, P.A.2    Taylor, C.J.3
  • 68
    • 84892381899 scopus 로고    scopus 로고
    • Expression analysis of intercellular adhesion molecule-2 (ICAM-2) in the context of classical cardiovascular risk factors in acute coronary syndrome patients
    • Glogowska-Ligus J., Dabek J., Zych-Twardowska E., Tkacz M. Expression analysis of intercellular adhesion molecule-2 (ICAM-2) in the context of classical cardiovascular risk factors in acute coronary syndrome patients. Archives of Medical Science 2013, 9(6):1035-1039. 10.5114/aoms.2012.28808.
    • (2013) Archives of Medical Science , vol.9 , Issue.6 , pp. 1035-1039
    • Glogowska-Ligus, J.1    Dabek, J.2    Zych-Twardowska, E.3    Tkacz, M.4
  • 70
    • 55549100240 scopus 로고    scopus 로고
    • Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome
    • Gomes V.A., Casella-Filho A., Chagas A.C., Tanus-Santos J.E. Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome. Nitric Oxide 2008, 19(4):345-350. S1089-8603(08)00365-0 [pii]. 10.1016/j.niox.2008.08.005.
    • (2008) Nitric Oxide , vol.19 , Issue.4 , pp. 345-350
    • Gomes, V.A.1    Casella-Filho, A.2    Chagas, A.C.3    Tanus-Santos, J.E.4
  • 71
    • 67649400418 scopus 로고    scopus 로고
    • Relationship between diabetes codes that affect medicare reimbursement (tier comorbidities) and outcomes in stroke rehabilitation
    • Graham J.E., Ripsin C.M., Deutsch A., Kuo Y.F., Markello S., Granger C.V., et al. Relationship between diabetes codes that affect medicare reimbursement (tier comorbidities) and outcomes in stroke rehabilitation. Archives of Physical Medicine and Rehabilitation 2009, 90(7):1110-1116. 10.1016/j.apmr.2009.01.014.
    • (2009) Archives of Physical Medicine and Rehabilitation , vol.90 , Issue.7 , pp. 1110-1116
    • Graham, J.E.1    Ripsin, C.M.2    Deutsch, A.3    Kuo, Y.F.4    Markello, S.5    Granger, C.V.6
  • 73
    • 0030049439 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury
    • Guyton K.Z., Liu Y., Gorospe M., Xu Q., Holbrook N.J. Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. The Journal of Biological Chemistry 1996, 271(8):4138-4142.
    • (1996) The Journal of Biological Chemistry , vol.271 , Issue.8 , pp. 4138-4142
    • Guyton, K.Z.1    Liu, Y.2    Gorospe, M.3    Xu, Q.4    Holbrook, N.J.5
  • 75
    • 84886254101 scopus 로고    scopus 로고
    • Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations
    • Hawkes C.A., Michalski D., Anders R., Nissel S., Grosche J., Bechmann I., et al. Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations. Experimental Neurology 2013, 250:270-281. 10.1016/j.expneurol.2013.09.020.
    • (2013) Experimental Neurology , vol.250 , pp. 270-281
    • Hawkes, C.A.1    Michalski, D.2    Anders, R.3    Nissel, S.4    Grosche, J.5    Bechmann, I.6
  • 76
    • 84907999588 scopus 로고    scopus 로고
    • Microglia and synaptic reorganization: Focus on the movement and functions of microglial processes
    • Hayashi Y., Nakanishi H. Microglia and synaptic reorganization: Focus on the movement and functions of microglial processes. Nihon Yakurigaku Zasshi 2013, 142(5):231-235.
    • (2013) Nihon Yakurigaku Zasshi , vol.142 , Issue.5 , pp. 231-235
    • Hayashi, Y.1    Nakanishi, H.2
  • 77
    • 84892514122 scopus 로고    scopus 로고
    • Homeostatic and injury-induced microglia behavior in the aging brain
    • Hefendehl J.K., Neher J.J., Suhs R.B., Kohsaka S., Skodras A., Jucker M. Homeostatic and injury-induced microglia behavior in the aging brain. Aging Cell 2014, 13(1):60-69. 10.1111/acel.12149.
    • (2014) Aging Cell , vol.13 , Issue.1 , pp. 60-69
    • Hefendehl, J.K.1    Neher, J.J.2    Suhs, R.B.3    Kohsaka, S.4    Skodras, A.5    Jucker, M.6
  • 79
    • 35748981199 scopus 로고    scopus 로고
    • Age-specific prevalence of the metabolic syndrome defined by the international diabetes federation and the national cholesterol education program: The Norwegian HUNT 2 study
    • 1471-2458-7-220 [pii]
    • Hildrum B., Mykletun A., Hole T., Midthjell K., Dahl A.A. Age-specific prevalence of the metabolic syndrome defined by the international diabetes federation and the national cholesterol education program: The Norwegian HUNT 2 study. BMC Public Health 2007, 7:220. 1471-2458-7-220 [pii]. 10.1186/1471-2458-7-220.
    • (2007) BMC Public Health , vol.7 , pp. 220
    • Hildrum, B.1    Mykletun, A.2    Hole, T.3    Midthjell, K.4    Dahl, A.A.5
  • 80
    • 84885976931 scopus 로고    scopus 로고
    • Epidemiology, pathophysiology, and treatment of hypertension in ischaemic stroke patients
    • Hisham N.F., Bayraktutan U. Epidemiology, pathophysiology, and treatment of hypertension in ischaemic stroke patients. Journal of Stroke and Cerebrovascular Diseases 2013, 22(7):e4-e14. 10.1016/j.jstrokecerebrovasdis.2012.05.001.
    • (2013) Journal of Stroke and Cerebrovascular Diseases , vol.22 , Issue.7 , pp. e4-e14
    • Hisham, N.F.1    Bayraktutan, U.2
  • 82
    • 0037154761 scopus 로고    scopus 로고
    • Age-related changes in GluR2 and NMDAR1 glutamate receptor subunit protein immunoreactivity in corticocortically projecting neurons in macaque and patas monkeys
    • Hof P.R., Duan H., Page T.L., Einstein M., Wicinski B., He Y., et al. Age-related changes in GluR2 and NMDAR1 glutamate receptor subunit protein immunoreactivity in corticocortically projecting neurons in macaque and patas monkeys. Brain Research 2002, 928(1-2):175-186. S0006899301033455 [pii].
    • (2002) Brain Research , vol.928 , Issue.1-2 , pp. 175-186
    • Hof, P.R.1    Duan, H.2    Page, T.L.3    Einstein, M.4    Wicinski, B.5    He, Y.6
  • 83
    • 0027164713 scopus 로고
    • Re-evaluating the role of astrocytes in blood-brain barrier induction
    • Holash J.A., Noden D.M., Stewart P.A. Re-evaluating the role of astrocytes in blood-brain barrier induction. Developmental Dynamics 1993, 197(1):14-25. 10.1002/aja.1001970103.
    • (1993) Developmental Dynamics , vol.197 , Issue.1 , pp. 14-25
    • Holash, J.A.1    Noden, D.M.2    Stewart, P.A.3
  • 84
    • 84896736653 scopus 로고    scopus 로고
    • Healthy aging in a cross-sectional study of Australian men: What has sex got to do with it?
    • Holden C.A., Collins V.R., Handelsman D.J., Jolley D., Pitts M. Healthy aging in a cross-sectional study of Australian men: What has sex got to do with it?. The Aging Male 2014, Men in Australia Telephone Survey Working, Group. 10.3109/13685538.2013.843167.
    • (2014) The Aging Male
    • Holden, C.A.1    Collins, V.R.2    Handelsman, D.J.3    Jolley, D.4    Pitts, M.5
  • 85
    • 84893709560 scopus 로고    scopus 로고
    • Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1beta
    • Hopp S.C., Royer S., Brothers H.M., Kaercher R.M., D'Angelo H., Bardou I., et al. Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1beta. Journal of Neuroimmunology 2014, 267(1-2):86-91. 10.1016/j.jneuroim.2013.12.010.
    • (2014) Journal of Neuroimmunology , vol.267 , Issue.1-2 , pp. 86-91
    • Hopp, S.C.1    Royer, S.2    Brothers, H.M.3    Kaercher, R.M.4    D'Angelo, H.5    Bardou, I.6
  • 86
    • 33845547792 scopus 로고    scopus 로고
    • Pathophysiology and therapy of experimental stroke
    • Hossmann K.A. Pathophysiology and therapy of experimental stroke. Cellular and Molecular Neurobiology 2006, 26(7-8):1057-1083. 10.1007/s10571-006-9008-1.
    • (2006) Cellular and Molecular Neurobiology , vol.26 , Issue.7-8 , pp. 1057-1083
    • Hossmann, K.A.1
  • 87
    • 70350349527 scopus 로고    scopus 로고
    • Pathophysiological basis of translational stroke research
    • 13176 [pii]
    • Hossmann K.A. Pathophysiological basis of translational stroke research. Folia Neuropathologica 2009, 47(3):213-227. 13176 [pii].
    • (2009) Folia Neuropathologica , vol.47 , Issue.3 , pp. 213-227
    • Hossmann, K.A.1
  • 88
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil G.S. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010, 140(6):900-917. S0092-8674(10)00187-X [pii]. 10.1016/j.cell.2010.02.034.
    • (2010) Cell , vol.140 , Issue.6 , pp. 900-917
    • Hotamisligil, G.S.1
  • 90
    • 84884535212 scopus 로고    scopus 로고
    • CKD and cardiovascular disease in the atherosclerosis risk in communities (ARIC) study: Interactions with age, sex, and race
    • Hui X., Matsushita K., Sang Y., Ballew S.H., Fulop T., Coresh J. CKD and cardiovascular disease in the atherosclerosis risk in communities (ARIC) study: Interactions with age, sex, and race. American Journal of Kidney Diseases 2013, 62(4):691-702. 10.1053/j.ajkd.2013.04.010.
    • (2013) American Journal of Kidney Diseases , vol.62 , Issue.4 , pp. 691-702
    • Hui, X.1    Matsushita, K.2    Sang, Y.3    Ballew, S.H.4    Fulop, T.5    Coresh, J.6
  • 91
    • 84856227885 scopus 로고    scopus 로고
    • Phagocytosis of neuronal debris by microglia is associated with neuronal damage in multiple sclerosis
    • Huizinga R., van der Star B.J., Kipp M., Jong R., Gerritsen W., Clarner T., et al. Phagocytosis of neuronal debris by microglia is associated with neuronal damage in multiple sclerosis. Glia 2012, 60(3):422-431. 10.1002/glia.22276.
    • (2012) Glia , vol.60 , Issue.3 , pp. 422-431
    • Huizinga, R.1    van der Star, B.J.2    Kipp, M.3    Jong, R.4    Gerritsen, W.5    Clarner, T.6
  • 92
    • 42649135605 scopus 로고    scopus 로고
    • Prevalence of moderate and severe renal insufficiency in older persons with hypertension, diabetes mellitus, coronary artery disease, peripheral arterial disease, ischemic stroke, or congestive heart failure in an academic nursing home
    • Joseph J., Koka M., Aronow W.S. Prevalence of moderate and severe renal insufficiency in older persons with hypertension, diabetes mellitus, coronary artery disease, peripheral arterial disease, ischemic stroke, or congestive heart failure in an academic nursing home. Journal of the American Medical Directors Association 2008, 9(4):257-259. 10.1016/j.jamda.2008.01.002.
    • (2008) Journal of the American Medical Directors Association , vol.9 , Issue.4 , pp. 257-259
    • Joseph, J.1    Koka, M.2    Aronow, W.S.3
  • 93
    • 84883555529 scopus 로고    scopus 로고
    • Midlife stroke risk and cognitive decline: A 10-year follow-up of the Whitehall II cohort study
    • Kaffashian S., Dugravot A., Brunner E.J., Sabia S., Ankri J., Kivimaki M., et al. Midlife stroke risk and cognitive decline: A 10-year follow-up of the Whitehall II cohort study. Alzheimers Dement 2013, 9(5):572-579. 10.1016/j.jalz.2012.07.001.
    • (2013) Alzheimers Dement , vol.9 , Issue.5 , pp. 572-579
    • Kaffashian, S.1    Dugravot, A.2    Brunner, E.J.3    Sabia, S.4    Ankri, J.5    Kivimaki, M.6
  • 94
    • 84880327581 scopus 로고    scopus 로고
    • Comparative analysis of cardiovascular disease risk factors influencing nonfatal acute coronary syndrome and ischemic stroke
    • Kastorini C.M., Georgousopoulou E., Vemmos K.N., Nikolaou V., Kantas D., Milionis H.J., et al. Comparative analysis of cardiovascular disease risk factors influencing nonfatal acute coronary syndrome and ischemic stroke. The American Journal of Cardiology 2013, 112(3):349-354. 10.1016/j.amjcard.2013.03.039.
    • (2013) The American Journal of Cardiology , vol.112 , Issue.3 , pp. 349-354
    • Kastorini, C.M.1    Georgousopoulou, E.2    Vemmos, K.N.3    Nikolaou, V.4    Kantas, D.5    Milionis, H.J.6
  • 95
    • 84871701721 scopus 로고    scopus 로고
    • Gene-environment interactions between methylenetetrahydrofolate reductase (MTHFR) 677C>T and metabolic syndrome for the prevalence of ischemic stroke in Koreans
    • Kim O.J., Hong S.H., Jeon Y.J., Oh S.H., Kim H.S., Park Y.S., et al. Gene-environment interactions between methylenetetrahydrofolate reductase (MTHFR) 677C>T and metabolic syndrome for the prevalence of ischemic stroke in Koreans. Neuroscience Letters 2013, 533:11-16. 10.1016/j.neulet.2012.11.031.
    • (2013) Neuroscience Letters , vol.533 , pp. 11-16
    • Kim, O.J.1    Hong, S.H.2    Jeon, Y.J.3    Oh, S.H.4    Kim, H.S.5    Park, Y.S.6
  • 96
    • 84865432697 scopus 로고    scopus 로고
    • Inhibitory effects of luteolin on transendothelial migration of monocytes and formation of lipid-laden macrophages
    • Kim M.S., Kim D.S., Kim H.S., Kang S.W., Kang Y.H. Inhibitory effects of luteolin on transendothelial migration of monocytes and formation of lipid-laden macrophages. Nutrition 2012, 28(10):1044-1054. 10.1016/j.nut.2011.12.003.
    • (2012) Nutrition , vol.28 , Issue.10 , pp. 1044-1054
    • Kim, M.S.1    Kim, D.S.2    Kim, H.S.3    Kang, S.W.4    Kang, Y.H.5
  • 99
    • 0031953601 scopus 로고    scopus 로고
    • Calcium in ischemic cell death
    • Kristian T., Siesjo B.K. Calcium in ischemic cell death. Stroke 1998, 29(3):705-718.
    • (1998) Stroke , vol.29 , Issue.3 , pp. 705-718
    • Kristian, T.1    Siesjo, B.K.2
  • 100
    • 84876362339 scopus 로고    scopus 로고
    • Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability
    • Krouwer V.J., Hekking L.H., Langelaar-Makkinje M., Regan-Klapisz E., Post J.A. Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability. Vascular Cell 2012, 4(1):12. 10.1186/2045-824X-4-12.
    • (2012) Vascular Cell , vol.4 , Issue.1 , pp. 12
    • Krouwer, V.J.1    Hekking, L.H.2    Langelaar-Makkinje, M.3    Regan-Klapisz, E.4    Post, J.A.5
  • 101
    • 33645066399 scopus 로고    scopus 로고
    • Metabolic syndrome and the risk of stroke in middle-aged men
    • 01.STR.0000204354.06965.44 [pii]
    • Kurl S., Laukkanen J.A., Niskanen L., Laaksonen D., Sivenius J., Nyyssonen K., et al. Metabolic syndrome and the risk of stroke in middle-aged men. Stroke 2006, 37(3):806-811. 01.STR.0000204354.06965.44 [pii]. 10.1161/01.STR.0000204354.06965.44.
    • (2006) Stroke , vol.37 , Issue.3 , pp. 806-811
    • Kurl, S.1    Laukkanen, J.A.2    Niskanen, L.3    Laaksonen, D.4    Sivenius, J.5    Nyyssonen, K.6
  • 102
    • 34648828570 scopus 로고    scopus 로고
    • Central arterial aging and the epidemic of systolic hypertension and atherosclerosis
    • Lakatta E.G. Central arterial aging and the epidemic of systolic hypertension and atherosclerosis. Journal of the American Society of Hypertension 2007, 1(5):302-340. 10.1016/j.jash.2007.05.001.
    • (2007) Journal of the American Society of Hypertension , vol.1 , Issue.5 , pp. 302-340
    • Lakatta, E.G.1
  • 103
    • 33847021463 scopus 로고    scopus 로고
    • Family history of hypertension is not an independent genetic factor predisposing to ischemic stroke subtypes
    • Laloux P., Ossemann M., Jamart J. Family history of hypertension is not an independent genetic factor predisposing to ischemic stroke subtypes. Clinical Neurology and Neurosurgery 2007, 109(3):247-249. 10.1016/j.clineuro.2006.09.005.
    • (2007) Clinical Neurology and Neurosurgery , vol.109 , Issue.3 , pp. 247-249
    • Laloux, P.1    Ossemann, M.2    Jamart, J.3
  • 104
    • 0036138535 scopus 로고    scopus 로고
    • Astrocytes mediate cerebral cortical neuronal axon and dendrite growth, in part, by release of fibroblast growth factor
    • Le R., Esquenazi S. Astrocytes mediate cerebral cortical neuronal axon and dendrite growth, in part, by release of fibroblast growth factor. Neurological Research 2002, 24(1):81-92. 10.1179/016164102101199459.
    • (2002) Neurological Research , vol.24 , Issue.1 , pp. 81-92
    • Le, R.1    Esquenazi, S.2
  • 106
    • 0034489693 scopus 로고    scopus 로고
    • Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats
    • Lee J., Duan W., Long J.M., Ingram D.K., Mattson M.P. Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats. Journal of Molecular Neuroscience 2000, 15(2):99-108. 10.1385/JMN:15:2:99.
    • (2000) Journal of Molecular Neuroscience , vol.15 , Issue.2 , pp. 99-108
    • Lee, J.1    Duan, W.2    Long, J.M.3    Ingram, D.K.4    Mattson, M.P.5
  • 107
    • 84888786160 scopus 로고    scopus 로고
    • Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats: Influence of aging and hypertension
    • Lee J.T., Liu H.L., Yang J.T., Yang S.T., Lin J.R., Lee T.H. Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats: Influence of aging and hypertension. Neuroscience 2014, 257:31-40. 10.1016/j.neuroscience.2013.10.066.
    • (2014) Neuroscience , vol.257 , pp. 31-40
    • Lee, J.T.1    Liu, H.L.2    Yang, J.T.3    Yang, S.T.4    Lin, J.R.5    Lee, T.H.6
  • 108
    • 84894159298 scopus 로고    scopus 로고
    • Comparison of the long-term results of roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: A systematic review and meta-analysis of randomized and nonrandomized trials
    • Li J.F., Lai D.D., Lin Z.H., Jiang T.Y., Zhang A.M., Dai J.F. Comparison of the long-term results of roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: A systematic review and meta-analysis of randomized and nonrandomized trials. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2014, 24(1):1-11. 10.1097/SLE.0000000000000041.
    • (2014) Surgical Laparoscopy, Endoscopy & Percutaneous Techniques , vol.24 , Issue.1 , pp. 1-11
    • Li, J.F.1    Lai, D.D.2    Lin, Z.H.3    Jiang, T.Y.4    Zhang, A.M.5    Dai, J.F.6
  • 109
    • 2442425937 scopus 로고    scopus 로고
    • Astrocytes contribute to regulation of extracellular calcium and potassium in the rat cerebral cortex during spreading depression
    • Lian X.Y., Stringer J.L. Astrocytes contribute to regulation of extracellular calcium and potassium in the rat cerebral cortex during spreading depression. Brain Research 2004, 1012(1-2):177-184. 10.1016/j.brainres.2004.04.011.
    • (2004) Brain Research , vol.1012 , Issue.1-2 , pp. 177-184
    • Lian, X.Y.1    Stringer, J.L.2
  • 110
    • 77956602111 scopus 로고    scopus 로고
    • Astrocytes retain their antioxidant capacity into advanced old age
    • Liddell J.R., Robinson S.R., Dringen R., Bishop G.M. Astrocytes retain their antioxidant capacity into advanced old age. Glia 2010, 58(12):1500-1509. 10.1002/glia.21024.
    • (2010) Glia , vol.58 , Issue.12 , pp. 1500-1509
    • Liddell, J.R.1    Robinson, S.R.2    Dringen, R.3    Bishop, G.M.4
  • 111
    • 84859905673 scopus 로고    scopus 로고
    • Subclinical atherosclerosis in a community-based elderly cohort: The Korean longitudinal study on health and aging
    • Lim S., Choi H.J., Shin H., Khang A.R., Kang S.M., Yoon J.W., et al. Subclinical atherosclerosis in a community-based elderly cohort: The Korean longitudinal study on health and aging. International Journal of Cardiology 2012, 155(1):126-133. 10.1016/j.ijcard.2011.05.054.
    • (2012) International Journal of Cardiology , vol.155 , Issue.1 , pp. 126-133
    • Lim, S.1    Choi, H.J.2    Shin, H.3    Khang, A.R.4    Kang, S.M.5    Yoon, J.W.6
  • 112
  • 113
    • 79952782058 scopus 로고    scopus 로고
    • Predictors of intracranial hemorrhage in patients taking anticoagulant and antiplatelet medication
    • Lin T.Y., Lee W.C., Soo K.M., Lin H.L. Predictors of intracranial hemorrhage in patients taking anticoagulant and antiplatelet medication. Journal of Trauma 2011, 70(3):764. 10.1097/TA.0b013e318206cb18.
    • (2011) Journal of Trauma , vol.70 , Issue.3 , pp. 764
    • Lin, T.Y.1    Lee, W.C.2    Soo, K.M.3    Lin, H.L.4
  • 114
    • 0034652426 scopus 로고    scopus 로고
    • Age-associated decline in gamma-glutamylcysteine synthetase gene expression in rats
    • Liu R., Choi J. Age-associated decline in gamma-glutamylcysteine synthetase gene expression in rats. Free Radical Biology & Medicine 2000, 28(4):566-574.
    • (2000) Free Radical Biology & Medicine , vol.28 , Issue.4 , pp. 566-574
    • Liu, R.1    Choi, J.2
  • 115
    • 84887199132 scopus 로고    scopus 로고
    • Effectiveness of a workplace training programme in improving social, communication and emotional skills for adults with autism and intellectual disability in Hong Kong-a pilot study
    • Liu K.P., Wong D., Chung A.C., Kwok N., Lam M.K., Yuen C.M., et al. Effectiveness of a workplace training programme in improving social, communication and emotional skills for adults with autism and intellectual disability in Hong Kong-a pilot study. Occupational Therapy International 2013, 20(4):198-204. 10.1002/oti.1356.
    • (2013) Occupational Therapy International , vol.20 , Issue.4 , pp. 198-204
    • Liu, K.P.1    Wong, D.2    Chung, A.C.3    Kwok, N.4    Lam, M.K.5    Yuen, C.M.6
  • 116
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • nrn1106 [pii]
    • Lo E.H., Dalkara T., Moskowitz M.A. Mechanisms, challenges and opportunities in stroke. Nature Reviews. Neuroscience 2003, 4(5):399-415. nrn1106 [pii]. 10.1038/nrn1106.
    • (2003) Nature Reviews. Neuroscience , vol.4 , Issue.5 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 117
  • 118
    • 0034948192 scopus 로고    scopus 로고
    • Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro
    • Lue L.F., Rydel R., Brigham E.F., Yang L.B., Hampel H., Murphy G.M., et al. Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro. Glia 2001, 35(1):72-79.
    • (2001) Glia , vol.35 , Issue.1 , pp. 72-79
    • Lue, L.F.1    Rydel, R.2    Brigham, E.F.3    Yang, L.B.4    Hampel, H.5    Murphy, G.M.6
  • 119
    • 84864923458 scopus 로고    scopus 로고
    • The role of diabetes and aging in the determinism of hypertension and the related cerebrovascular complications
    • Malaguarnera M., Vacante M., Frazzetto P.M., Motta M. The role of diabetes and aging in the determinism of hypertension and the related cerebrovascular complications. Archives of Gerontology and Geriatrics 2012, 55(2):221-225. 10.1016/j.archger.2011.08.008.
    • (2012) Archives of Gerontology and Geriatrics , vol.55 , Issue.2 , pp. 221-225
    • Malaguarnera, M.1    Vacante, M.2    Frazzetto, P.M.3    Motta, M.4
  • 120
    • 84862861541 scopus 로고    scopus 로고
    • Posturo-respiratory synchronization: Effects of aging and stroke
    • Manor B.D., Hu K., Peng C.K., Lipsitz L.A., Novak V. Posturo-respiratory synchronization: Effects of aging and stroke. Gait & Posture 2012, 36(2):254-259. 10.1016/j.gaitpost.2012.03.002.
    • (2012) Gait & Posture , vol.36 , Issue.2 , pp. 254-259
    • Manor, B.D.1    Hu, K.2    Peng, C.K.3    Lipsitz, L.A.4    Novak, V.5
  • 121
    • 84884393593 scopus 로고    scopus 로고
    • Differential effects of aging and sex on stroke induced inflammation across the lifespan
    • Manwani B., Liu F., Scranton V., Hammond M.D., Sansing L.H., McCullough L.D. Differential effects of aging and sex on stroke induced inflammation across the lifespan. Experimental Neurology 2013, 249:120-131. 10.1016/j.expneurol.2013.08.011.
    • (2013) Experimental Neurology , vol.249 , pp. 120-131
    • Manwani, B.1    Liu, F.2    Scranton, V.3    Hammond, M.D.4    Sansing, L.H.5    McCullough, L.D.6
  • 124
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • nature02621 [pii]
    • Mattson M.P. Pathways towards and away from Alzheimer's disease. Nature 2004, 430(7000):631-639. nature02621 [pii]. 10.1038/nature02621.
    • (2004) Nature , vol.430 , Issue.7000 , pp. 631-639
    • Mattson, M.P.1
  • 125
    • 33645299025 scopus 로고    scopus 로고
    • Ageing and neuronal vulnerability
    • nrn1886 [pii]
    • Mattson M.P., Magnus T. Ageing and neuronal vulnerability. Nature Reviews. Neuroscience 2006, 7(4):278-294. nrn1886 [pii]. 10.1038/nrn1886.
    • (2006) Nature Reviews. Neuroscience , vol.7 , Issue.4 , pp. 278-294
    • Mattson, M.P.1    Magnus, T.2
  • 126
    • 84896739428 scopus 로고    scopus 로고
    • The influence of diet and nutrients on platelet function
    • McEwen B.J. The influence of diet and nutrients on platelet function. Seminars in Thrombosis and Hemostasis 2014, 10.1055/s-0034-1365839.
    • (2014) Seminars in Thrombosis and Hemostasis
    • McEwen, B.J.1
  • 128
    • 42649097901 scopus 로고    scopus 로고
    • The effects of aging, injury and disease on microglial function: A case for cellular senescence
    • Miller K.R., Streit W.J. The effects of aging, injury and disease on microglial function: A case for cellular senescence. Neuron Glia Biology 2007, 3(3):245-253. 10.1017/S1740925X08000136.
    • (2007) Neuron Glia Biology , vol.3 , Issue.3 , pp. 245-253
    • Miller, K.R.1    Streit, W.J.2
  • 129
    • 0037292314 scopus 로고    scopus 로고
    • Age-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1)
    • Mooradian A.D., Haas M.J., Chehade J.M. Age-related changes in rat cerebral occludin and zonula occludens-1 (ZO-1). Mechanisms of Ageing and Development 2003, 124(2):143-146.
    • (2003) Mechanisms of Ageing and Development , vol.124 , Issue.2 , pp. 143-146
    • Mooradian, A.D.1    Haas, M.J.2    Chehade, J.M.3
  • 131
    • 44849094781 scopus 로고    scopus 로고
    • Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
    • Morimoto R.I. Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes & Development 2008, 22(11):1427-1438. 10.1101/gad.1657108.
    • (2008) Genes & Development , vol.22 , Issue.11 , pp. 1427-1438
    • Morimoto, R.I.1
  • 132
    • 84900790372 scopus 로고    scopus 로고
    • Treatment of hypertension in older persons: What is the evidence?
    • Morley J.E. Treatment of hypertension in older persons: What is the evidence?. Drugs & Aging 2014, 31(5):331-337. 10.1007/s40266-014-0171-7.
    • (2014) Drugs & Aging , vol.31 , Issue.5 , pp. 331-337
    • Morley, J.E.1
  • 133
    • 77956881582 scopus 로고    scopus 로고
    • Association of the -344C/T aldosterone synthase (CYP11B2) gene variant with hypertension and stroke
    • Munshi A., Sharma V., Kaul S., Rajeshwar K., Babu M.S., Shafi G., et al. Association of the -344C/T aldosterone synthase (CYP11B2) gene variant with hypertension and stroke. Journal of the Neurological Sciences 2010, 296(1-2):34-38. 10.1016/j.jns.2010.06.013.
    • (2010) Journal of the Neurological Sciences , vol.296 , Issue.1-2 , pp. 34-38
    • Munshi, A.1    Sharma, V.2    Kaul, S.3    Rajeshwar, K.4    Babu, M.S.5    Shafi, G.6
  • 134
    • 84855490908 scopus 로고    scopus 로고
    • Diabetes, body mass index and the excess risk of coronary heart disease, ischemic and hemorrhagic stroke in the Asia pacific cohort studies collaboration
    • Murakami Y., Huxley R.R., Lam T.H., Tsukinoki R., Fang X., Kim H.C., et al. Diabetes, body mass index and the excess risk of coronary heart disease, ischemic and hemorrhagic stroke in the Asia pacific cohort studies collaboration. Preventive Medicine 2012, 54(1):38-41. 10.1016/j.ypmed.2011.10.010.
    • (2012) Preventive Medicine , vol.54 , Issue.1 , pp. 38-41
    • Murakami, Y.1    Huxley, R.R.2    Lam, T.H.3    Tsukinoki, R.4    Fang, X.5    Kim, H.C.6
  • 135
    • 67349217063 scopus 로고    scopus 로고
    • ER and aging-protein folding and the ER stress response
    • Naidoo N. ER and aging-protein folding and the ER stress response. Ageing Research Reviews 2009, 8(3):150-159. S1568-1637(09)00017-8 [pii]. 10.1016/j.arr.2009.03.001.
    • (2009) Ageing Research Reviews , vol.8 , Issue.3 , pp. 150-159
    • Naidoo, N.1
  • 136
    • 59349112140 scopus 로고    scopus 로고
    • Microglial clearance function in health and disease
    • Napoli I., Neumann H. Microglial clearance function in health and disease. Neuroscience 2009, 158(3):1030-1038. 10.1016/j.neuroscience.2008.06.046.
    • (2009) Neuroscience , vol.158 , Issue.3 , pp. 1030-1038
    • Napoli, I.1    Neumann, H.2
  • 137
    • 84887615073 scopus 로고    scopus 로고
    • Decreased stroke volume-brachial pulse pressure ratio in patients with type 2 diabetes over 50 years: The role of peripheral neuropathy
    • Nguyen M.T., Pham I., Chemla D., Valensi P., Cosson E. Decreased stroke volume-brachial pulse pressure ratio in patients with type 2 diabetes over 50 years: The role of peripheral neuropathy. Nutrition, Metabolism, and Cardiovascular Diseases 2013, 23(11):1093-1100. 10.1016/j.numecd.2013.01.008.
    • (2013) Nutrition, Metabolism, and Cardiovascular Diseases , vol.23 , Issue.11 , pp. 1093-1100
    • Nguyen, M.T.1    Pham, I.2    Chemla, D.3    Valensi, P.4    Cosson, E.5
  • 138
    • 84865629675 scopus 로고    scopus 로고
    • Tissue plasminogen activator treatment of stroke in type-1 diabetes rats
    • Ning R., Chopp M., Yan T., Zacharek A., Zhang C., Roberts C., et al. Tissue plasminogen activator treatment of stroke in type-1 diabetes rats. Neuroscience 2012, 222:326-332. 10.1016/j.neuroscience.2012.07.018.
    • (2012) Neuroscience , vol.222 , pp. 326-332
    • Ning, R.1    Chopp, M.2    Yan, T.3    Zacharek, A.4    Zhang, C.5    Roberts, C.6
  • 139
    • 84889595557 scopus 로고    scopus 로고
    • Neamine induces neuroprotection after acute ischemic stroke in type one diabetic rats
    • Ning R., Chopp M., Zacharek A., Yan T., Zhang C., Roberts C., et al. Neamine induces neuroprotection after acute ischemic stroke in type one diabetic rats. Neuroscience 2014, 257:76-85. 10.1016/j.neuroscience.2013.10.071.
    • (2014) Neuroscience , vol.257 , pp. 76-85
    • Ning, R.1    Chopp, M.2    Zacharek, A.3    Yan, T.4    Zhang, C.5    Roberts, C.6
  • 140
    • 84894384733 scopus 로고    scopus 로고
    • The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: Focus on astrocytes
    • Niranjan R. The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: Focus on astrocytes. Molecular Neurobiology 2013, 10.1007/s12035-013-8483-x.
    • (2013) Molecular Neurobiology
    • Niranjan, R.1
  • 141
    • 81355132325 scopus 로고    scopus 로고
    • Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
    • Njie E.G., Boelen E., Stassen F.R., Steinbusch H.W., Borchelt D.R., Streit W.J. Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function. Neurobiology of Aging 2012, 33(1):195.e1-195.e12. 10.1016/j.neurobiolaging.2010.05.008.
    • (2012) Neurobiology of Aging , vol.33 , Issue.1 , pp. 195e1-195e12
    • Njie, E.G.1    Boelen, E.2    Stassen, F.R.3    Steinbusch, H.W.4    Borchelt, D.R.5    Streit, W.J.6
  • 142
    • 19444378229 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity
    • O'Callaghan J.P., Sriram K. Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity. Expert Opinion on Drug Safety 2005, 4(3):433-442. 10.1517/14740338.4.3.433.
    • (2005) Expert Opinion on Drug Safety , vol.4 , Issue.3 , pp. 433-442
    • O'Callaghan, J.P.1    Sriram, K.2
  • 143
    • 80053575339 scopus 로고    scopus 로고
    • Dynamic motility of microglia: Purinergic modulation of microglial movement in the normal and pathological brain
    • Ohsawa K., Kohsaka S. Dynamic motility of microglia: Purinergic modulation of microglial movement in the normal and pathological brain. Glia 2011, 59(12):1793-1799. 10.1002/glia.21238.
    • (2011) Glia , vol.59 , Issue.12 , pp. 1793-1799
    • Ohsawa, K.1    Kohsaka, S.2
  • 144
    • 33748082993 scopus 로고    scopus 로고
    • Aging, smooth muscle cells and vascular pathobiology: Implications for atherosclerosis
    • Orlandi A., Bochaton-Piallat M.L., Gabbiani G., Spagnoli L.G. Aging, smooth muscle cells and vascular pathobiology: Implications for atherosclerosis. Atherosclerosis 2006, 188(2):221-230. 10.1016/j.atherosclerosis.2006.01.018.
    • (2006) Atherosclerosis , vol.188 , Issue.2 , pp. 221-230
    • Orlandi, A.1    Bochaton-Piallat, M.L.2    Gabbiani, G.3    Spagnoli, L.G.4
  • 145
    • 84855966721 scopus 로고    scopus 로고
    • Role of endoplasmic reticulum stress in metabolic disease and other disorders
    • Ozcan L., Tabas I. Role of endoplasmic reticulum stress in metabolic disease and other disorders. Annual Review of Medicine 2012, 63:317-328. 10.1146/annurev-med-043010-144749.
    • (2012) Annual Review of Medicine , vol.63 , pp. 317-328
    • Ozcan, L.1    Tabas, I.2
  • 146
    • 0342618475 scopus 로고    scopus 로고
    • Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses
    • Papadopoulos M.C., Koumenis I.L., Yuan T.Y., Giffard R.G. Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses. Neuroscience 1998, 82(3):915-925.
    • (1998) Neuroscience , vol.82 , Issue.3 , pp. 915-925
    • Papadopoulos, M.C.1    Koumenis, I.L.2    Yuan, T.Y.3    Giffard, R.G.4
  • 147
    • 0037448097 scopus 로고    scopus 로고
    • Age-related changes in neuronal glucose uptake in response to glutamate and beta-amyloid
    • Patel J.R., Brewer G.J. Age-related changes in neuronal glucose uptake in response to glutamate and beta-amyloid. Journal of Neuroscience Research 2003, 72(4):527-536. 10.1002/jnr.10602.
    • (2003) Journal of Neuroscience Research , vol.72 , Issue.4 , pp. 527-536
    • Patel, J.R.1    Brewer, G.J.2
  • 149
    • 83055181916 scopus 로고    scopus 로고
    • Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice
    • Perego C., Fumagalli S., De Simoni M.G. Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice. Journal of Neuroinflammation 2011, 8:174. 10.1186/1742-2094-8-174.
    • (2011) Journal of Neuroinflammation , vol.8 , pp. 174
    • Perego, C.1    Fumagalli, S.2    De Simoni, M.G.3
  • 150
    • 84894477288 scopus 로고    scopus 로고
    • Racial and socioeconomic disparities in sleep and chronic disease: Results of a longitudinal investigation
    • Piccolo R.S., Yang M., Bliwise D.L., Yaggi H.K., Araujo A.B. Racial and socioeconomic disparities in sleep and chronic disease: Results of a longitudinal investigation. Ethnicity & Disease 2013, 23(4):499-507.
    • (2013) Ethnicity & Disease , vol.23 , Issue.4 , pp. 499-507
    • Piccolo, R.S.1    Yang, M.2    Bliwise, D.L.3    Yaggi, H.K.4    Araujo, A.B.5
  • 151
    • 84890426420 scopus 로고    scopus 로고
    • Metabolic syndrome, hypertension, and diabetes mellitus after gastric banding: The role of aging and of duration of obesity
    • Pontiroli A.E., Alberto M., Paganelli M., Saibene A., Busetto L. Metabolic syndrome, hypertension, and diabetes mellitus after gastric banding: The role of aging and of duration of obesity. Surgery for Obesity and Related Diseases 2013, 9(6):894-900. 10.1016/j.soard.2013.04.001.
    • (2013) Surgery for Obesity and Related Diseases , vol.9 , Issue.6 , pp. 894-900
    • Pontiroli, A.E.1    Alberto, M.2    Paganelli, M.3    Saibene, A.4    Busetto, L.5
  • 153
  • 154
    • 84868282410 scopus 로고    scopus 로고
    • Neuroprotective actions of methylene blue and its derivatives
    • Poteet E., Winters A., Yan L.J., Shufelt K., Green K.N., Simpkins J.W., et al. Neuroprotective actions of methylene blue and its derivatives. PLoS One 2012, 7(10):e48279. 10.1371/journal.pone.0048279.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e48279
    • Poteet, E.1    Winters, A.2    Yan, L.J.3    Shufelt, K.4    Green, K.N.5    Simpkins, J.W.6
  • 158
    • 0035662961 scopus 로고    scopus 로고
    • Changes of astrocytes in retinal ageing and age-related macular degeneration
    • Ramirez J.M., Ramirez A.I., Salazar J.J., de Hoz R., Trivino A. Changes of astrocytes in retinal ageing and age-related macular degeneration. Experimental Eye Research 2001, 73(5):601-615. 10.1006/exer.2001.1061.
    • (2001) Experimental Eye Research , vol.73 , Issue.5 , pp. 601-615
    • Ramirez, J.M.1    Ramirez, A.I.2    Salazar, J.J.3    de Hoz, R.4    Trivino, A.5
  • 159
    • 52449099245 scopus 로고    scopus 로고
    • PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: The Cardiovascular Health Study
    • Reiner A.P., Carty C.L., Jenny N.S., Nievergelt C., Cushman M., Stearns-Kurosawa D.J., et al. PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: The Cardiovascular Health Study. Journal of Thrombosis and Haemostasis 2008, 6(10):1625-1632. 10.1111/j.1538-7836.2008.03118.x.
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.10 , pp. 1625-1632
    • Reiner, A.P.1    Carty, C.L.2    Jenny, N.S.3    Nievergelt, C.4    Cushman, M.5    Stearns-Kurosawa, D.J.6
  • 161
    • 45549122280 scopus 로고    scopus 로고
    • Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the congestive heart failure, hypertension, age >75, diabetes mellitus, and prior stroke or transient ischemic attack (CHADS2) risk stratification scheme
    • Rietbrock S., Heeley E., Plumb J., van Staa T. Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the congestive heart failure, hypertension, age >75, diabetes mellitus, and prior stroke or transient ischemic attack (CHADS2) risk stratification scheme. American Heart Journal 2008, 156(1):57-64. 10.1016/j.ahj.2008.03.010.
    • (2008) American Heart Journal , vol.156 , Issue.1 , pp. 57-64
    • Rietbrock, S.1    Heeley, E.2    Plumb, J.3    van Staa, T.4
  • 163
    • 67651100556 scopus 로고    scopus 로고
    • Impaired cell proliferation in the subventricular zone in an Alzheimer's disease model
    • Rodriguez J.J., Jones V.C., Verkhratsky A. Impaired cell proliferation in the subventricular zone in an Alzheimer's disease model. Neuroreport 2009, 20(10):907-912. 10.1097/WNR.0b013e32832be77d.
    • (2009) Neuroreport , vol.20 , Issue.10 , pp. 907-912
    • Rodriguez, J.J.1    Jones, V.C.2    Verkhratsky, A.3
  • 164
    • 84891686296 scopus 로고    scopus 로고
    • Relationship of obesity and insulin resistance with the cerebrovascular reactivity: A case control study
    • Rodriguez-Flores M., Garcia-Garcia E., Cano-Nigenda C.V., Cantu-Brito C. Relationship of obesity and insulin resistance with the cerebrovascular reactivity: A case control study. Cardiovascular Diabetology 2014, 13(1):2. 10.1186/1475-2840-13-2.
    • (2014) Cardiovascular Diabetology , vol.13 , Issue.1 , pp. 2
    • Rodriguez-Flores, M.1    Garcia-Garcia, E.2    Cano-Nigenda, C.V.3    Cantu-Brito, C.4
  • 166
    • 32044452456 scopus 로고    scopus 로고
    • Influence of age on stroke outcome following transient focal ischemia
    • Rosen C.L., Dinapoli V.A., Nagamine T., Crocco T. Influence of age on stroke outcome following transient focal ischemia. Journal of Neurosurgery 2005, 103(4):687-694. 10.3171/jns.2005.103.4.0687.
    • (2005) Journal of Neurosurgery , vol.103 , Issue.4 , pp. 687-694
    • Rosen, C.L.1    Dinapoli, V.A.2    Nagamine, T.3    Crocco, T.4
  • 167
    • 0031178776 scopus 로고    scopus 로고
    • American Heart Association Prevention Conference IV. Prevention and rehabilitation of stroke. Risk factors
    • Sacco R.L., Benjamin E.J., Broderick J.P., Dyken M., Easton J.D., Feinberg W.M., et al. American Heart Association Prevention Conference IV. Prevention and rehabilitation of stroke. Risk factors. Stroke 1997, 28(7):1507-1517.
    • (1997) Stroke , vol.28 , Issue.7 , pp. 1507-1517
    • Sacco, R.L.1    Benjamin, E.J.2    Broderick, J.P.3    Dyken, M.4    Easton, J.D.5    Feinberg, W.M.6
  • 168
    • 79956306304 scopus 로고    scopus 로고
    • Cerebral capillary endothelial cells are covered by the VEGF-expressing foot processes of astrocytes
    • Saito T., Shibasaki K., Kurachi M., Puentes S., Mikuni M., Ishizaki Y. Cerebral capillary endothelial cells are covered by the VEGF-expressing foot processes of astrocytes. Neuroscience Letters 2011, 497(2):116-121. 10.1016/j.neulet.2011.04.043.
    • (2011) Neuroscience Letters , vol.497 , Issue.2 , pp. 116-121
    • Saito, T.1    Shibasaki, K.2    Kurachi, M.3    Puentes, S.4    Mikuni, M.5    Ishizaki, Y.6
  • 169
  • 170
    • 84893382465 scopus 로고    scopus 로고
    • Genetic modifiers of obesity and bariatric surgery outcomes
    • Samantha Sevilla M., Hubal M.J. Genetic modifiers of obesity and bariatric surgery outcomes. Seminars in Pediatric Surgery 2014, 23(1):43-48. 10.1053/j.sempedsurg.2013.10.017.
    • (2014) Seminars in Pediatric Surgery , vol.23 , Issue.1 , pp. 43-48
    • Samantha Sevilla, M.1    Hubal, M.J.2
  • 171
    • 73449129665 scopus 로고    scopus 로고
    • Age-dependent response of CCAAT/enhancer binding proteins following traumatic brain injury in mice
    • Sandhir R., Berman N.E. Age-dependent response of CCAAT/enhancer binding proteins following traumatic brain injury in mice. Neurochemistry International 2010, 56(1):188-193. S0197-0186(09)00282-4 [pii]. 10.1016/j.neuint.2009.10.002.
    • (2010) Neurochemistry International , vol.56 , Issue.1 , pp. 188-193
    • Sandhir, R.1    Berman, N.E.2
  • 172
    • 0036082232 scopus 로고    scopus 로고
    • Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes
    • Sandhu S.K., Kaur G. Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes. Biogerontology 2002, 3(3):161-173.
    • (2002) Biogerontology , vol.3 , Issue.3 , pp. 161-173
    • Sandhu, S.K.1    Kaur, G.2
  • 173
    • 0037320032 scopus 로고    scopus 로고
    • Role of astrocytes in the maintenance and modulation of glutamatergic and GABAergic neurotransmission
    • Schousboe A. Role of astrocytes in the maintenance and modulation of glutamatergic and GABAergic neurotransmission. Neurochemical Research 2003, 28(2):347-352.
    • (2003) Neurochemical Research , vol.28 , Issue.2 , pp. 347-352
    • Schousboe, A.1
  • 174
    • 61849106008 scopus 로고    scopus 로고
    • The migraine association with cardiac anomalies, cardiovascular disease, and stroke
    • Schwedt T.J. The migraine association with cardiac anomalies, cardiovascular disease, and stroke. Neurologic Clinics 2009, 27(2):513-523. 10.1016/j.ncl.2008.11.006.
    • (2009) Neurologic Clinics , vol.27 , Issue.2 , pp. 513-523
    • Schwedt, T.J.1
  • 175
    • 84924980263 scopus 로고    scopus 로고
    • Changes in body weight and blood pressure: Paradoxical outcome events in overweight and obese subjects with cardiovascular disease
    • Seimon R.V., Espinoza D., Ivers L., Gebski V., Finer N., Legler U.F., et al. Changes in body weight and blood pressure: Paradoxical outcome events in overweight and obese subjects with cardiovascular disease. International Journal of Obesity 2014, 10.1038/ijo.2014.2.
    • (2014) International Journal of Obesity
    • Seimon, R.V.1    Espinoza, D.2    Ivers, L.3    Gebski, V.4    Finer, N.5    Legler, U.F.6
  • 177
    • 84896887907 scopus 로고    scopus 로고
    • Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium
    • Shiroto T., Romero N., Sugiyama T., Sartoretto J.L., Kalwa H., Yan Z., et al. Caveolin-1 is a critical determinant of autophagy, metabolic switching, and oxidative stress in vascular endothelium. PLoS One 2014, 9(2):e87871. 10.1371/journal.pone.0087871.
    • (2014) PLoS One , vol.9 , Issue.2 , pp. e87871
    • Shiroto, T.1    Romero, N.2    Sugiyama, T.3    Sartoretto, J.L.4    Kalwa, H.5    Yan, Z.6
  • 178
    • 0035067438 scopus 로고    scopus 로고
    • The selective vulnerability of nerve cells in Huntington's disease
    • nan299 [pii]
    • Sieradzan K.A., Mann D.M. The selective vulnerability of nerve cells in Huntington's disease. Neuropathology and Applied Neurobiology 2001, 27(1):1-21. nan299 [pii].
    • (2001) Neuropathology and Applied Neurobiology , vol.27 , Issue.1 , pp. 1-21
    • Sieradzan, K.A.1    Mann, D.M.2
  • 179
    • 79956203683 scopus 로고    scopus 로고
    • Vascular mechanisms in the pathogenesis of stroke
    • Sierra C., Coca A., Schiffrin E.L. Vascular mechanisms in the pathogenesis of stroke. Current Hypertension Reports 2011, 13(3):200-207. 10.1007/s11906-011-0195-x.
    • (2011) Current Hypertension Reports , vol.13 , Issue.3 , pp. 200-207
    • Sierra, C.1    Coca, A.2    Schiffrin, E.L.3
  • 180
    • 0032420244 scopus 로고    scopus 로고
    • Hormone replacement therapy: Cardiovascular benefits for aging women
    • Sites C.K. Hormone replacement therapy: Cardiovascular benefits for aging women. Coronary Artery Disease 1998, 9(12):789-793.
    • (1998) Coronary Artery Disease , vol.9 , Issue.12 , pp. 789-793
    • Sites, C.K.1
  • 181
    • 79960098769 scopus 로고    scopus 로고
    • Outcome of first-ever acute ischemic stroke in the elderly
    • Soares I., Abecasis P., Ferro J.M. Outcome of first-ever acute ischemic stroke in the elderly. Archives of Gerontology and Geriatrics 2011, 53(2):e81-e87. 10.1016/j.archger.2010.06.019.
    • (2011) Archives of Gerontology and Geriatrics , vol.53 , Issue.2 , pp. e81-e87
    • Soares, I.1    Abecasis, P.2    Ferro, J.M.3
  • 182
    • 84882485664 scopus 로고    scopus 로고
    • Age-related changes in brain support cells: Implications for stroke severity
    • Sohrabji F., Bake S., Lewis D.K. Age-related changes in brain support cells: Implications for stroke severity. Neurochemistry International 2013, 63(4):291-301. 10.1016/j.neuint.2013.06.013.
    • (2013) Neurochemistry International , vol.63 , Issue.4 , pp. 291-301
    • Sohrabji, F.1    Bake, S.2    Lewis, D.K.3
  • 183
    • 84894230780 scopus 로고    scopus 로고
    • Obesity indices and inflammatory markers in obese non-diabetic normo- and hypertensive patients: A comparative pilot study
    • St Pie M., St Pie A., Wlaze R.N., Paradowski M., Banach M., Rysz J. Obesity indices and inflammatory markers in obese non-diabetic normo- and hypertensive patients: A comparative pilot study. Lipids in Health and Disease 2014, 13(1):29. 10.1186/1476-511X-13-29.
    • (2014) Lipids in Health and Disease , vol.13 , Issue.1 , pp. 29
    • St Pie, M.1    St Pie, A.2    Wlaze, R.N.3    Paradowski, M.4    Banach, M.5    Rysz, J.6
  • 184
    • 79954571076 scopus 로고    scopus 로고
    • Therapeutic targets for neuroprotection in acute ischemic stroke: Lost in translation?
    • Stankowski J.N., Gupta R. Therapeutic targets for neuroprotection in acute ischemic stroke: Lost in translation?. Antioxidants & Redox Signaling 2011, 14(10):1841-1851. 10.1089/ars.2010.3292.
    • (2011) Antioxidants & Redox Signaling , vol.14 , Issue.10 , pp. 1841-1851
    • Stankowski, J.N.1    Gupta, R.2
  • 185
    • 84871322803 scopus 로고    scopus 로고
    • Astrocyte activation and wound healing in intact-skull mouse after focal brain injury
    • Suzuki T., Sakata H., Kato C., Connor J.A., Morita M. Astrocyte activation and wound healing in intact-skull mouse after focal brain injury. European Journal of Neuroscience 2012, 36(12):3653-3664. 10.1111/j.1460-9568.2012.08280.x.
    • (2012) European Journal of Neuroscience , vol.36 , Issue.12 , pp. 3653-3664
    • Suzuki, T.1    Sakata, H.2    Kato, C.3    Connor, J.A.4    Morita, M.5
  • 186
  • 187
    • 84895115721 scopus 로고    scopus 로고
    • Risk factors for cerebrovascular disease mortality among the elderly in Beijing: A competing risk analysis
    • Tang Z., Zhou T., Luo Y., Xie C., Huo D., Tao L., et al. Risk factors for cerebrovascular disease mortality among the elderly in Beijing: A competing risk analysis. PLoS One 2014, 9(2):e87884. 10.1371/journal.pone.0087884.
    • (2014) PLoS One , vol.9 , Issue.2 , pp. e87884
    • Tang, Z.1    Zhou, T.2    Luo, Y.3    Xie, C.4    Huo, D.5    Tao, L.6
  • 188
    • 15244350494 scopus 로고    scopus 로고
    • Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand
    • Taylor D.L., Jones F., Kubota E.S., Pocock J.M. Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. The Journal of Neuroscience 2005, 25(11):2952-2964. 10.1523/JNEUROSCI.4456-04.2005.
    • (2005) The Journal of Neuroscience , vol.25 , Issue.11 , pp. 2952-2964
    • Taylor, D.L.1    Jones, F.2    Kubota, E.S.3    Pocock, J.M.4
  • 189
    • 84876860938 scopus 로고    scopus 로고
    • An anxious heart: Anxiety and the onset of cardiovascular diseases
    • Thurston R.C., Rewak M., Kubzansky L.D. An anxious heart: Anxiety and the onset of cardiovascular diseases. Progress in Cardiovascular Diseases 2013, 55(6):524-537. 10.1016/j.pcad.2013.03.007.
    • (2013) Progress in Cardiovascular Diseases , vol.55 , Issue.6 , pp. 524-537
    • Thurston, R.C.1    Rewak, M.2    Kubzansky, L.D.3
  • 190
    • 84887041623 scopus 로고    scopus 로고
    • Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension
    • Toth P., Tucsek Z., Sosnowska D., Gautam T., Mitschelen M., Tarantini S., et al. Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. Journal of Cerebral Blood Flow and Metabolism 2013, 33(11):1732-1742. 10.1038/jcbfm.2013.143.
    • (2013) Journal of Cerebral Blood Flow and Metabolism , vol.33 , Issue.11 , pp. 1732-1742
    • Toth, P.1    Tucsek, Z.2    Sosnowska, D.3    Gautam, T.4    Mitschelen, M.5    Tarantini, S.6
  • 191
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
    • Trotti D., Danbolt N.C., Volterra A. Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?. Trends in Pharmacological Sciences 1998, 19(8):328-334.
    • (1998) Trends in Pharmacological Sciences , vol.19 , Issue.8 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 192
    • 84869090395 scopus 로고    scopus 로고
    • Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events
    • Tsimikas S., Willeit P., Willeit J., Santer P., Mayr M., Xu Q., et al. Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events. Journal of the American College of Cardiology 2012, 60(21):2218-2229. 10.1016/j.jacc.2012.08.979.
    • (2012) Journal of the American College of Cardiology , vol.60 , Issue.21 , pp. 2218-2229
    • Tsimikas, S.1    Willeit, P.2    Willeit, J.3    Santer, P.4    Mayr, M.5    Xu, Q.6
  • 193
    • 84908376800 scopus 로고    scopus 로고
    • Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: Effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease
    • glt177 [pii]
    • Tucsek Z., Toth P., Sosnowska D., Gautam T., Mitschelen M., Koller A., et al. Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: Effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2013, glt177 [pii]. 10.1093/gerona/glt177.
    • (2013) The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
    • Tucsek, Z.1    Toth, P.2    Sosnowska, D.3    Gautam, T.4    Mitschelen, M.5    Koller, A.6
  • 194
    • 84877761687 scopus 로고    scopus 로고
    • The science of cerebral ischemia and the quest for neuroprotection: Navigating past failure to future success
    • Turner R.C., Dodson S.C., Rosen C.L., Huber J.D. The science of cerebral ischemia and the quest for neuroprotection: Navigating past failure to future success. Journal of Neurosurgery 2013, 118(5):1072-1085. 10.3171/2012.11.JNS12408.
    • (2013) Journal of Neurosurgery , vol.118 , Issue.5 , pp. 1072-1085
    • Turner, R.C.1    Dodson, S.C.2    Rosen, C.L.3    Huber, J.D.4
  • 195
    • 84858444155 scopus 로고    scopus 로고
    • The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes
    • Vaidya A., Williams J.S. The relationship between vitamin D and the renin-angiotensin system in the pathophysiology of hypertension, kidney disease, and diabetes. Metabolism 2012, 61(4):450-458. 10.1016/j.metabol.2011.09.007.
    • (2012) Metabolism , vol.61 , Issue.4 , pp. 450-458
    • Vaidya, A.1    Williams, J.S.2
  • 196
    • 84893193652 scopus 로고    scopus 로고
    • The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: A collaborative analysis of ten large cohort studies
    • van Vliet-Ostaptchouk J.V., Nuotio M.L., Slagter S.N., Doiron D., Fischer K., Foco L., et al. The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: A collaborative analysis of ten large cohort studies. BMC Endocrine Disorders 2014, 14(1):9. 10.1186/1472-6823-14-9.
    • (2014) BMC Endocrine Disorders , vol.14 , Issue.1 , pp. 9
    • van Vliet-Ostaptchouk, J.V.1    Nuotio, M.L.2    Slagter, S.N.3    Doiron, D.4    Fischer, K.5    Foco, L.6
  • 197
    • 0033953257 scopus 로고    scopus 로고
    • Role of astrocytes in the clearance of excess extracellular potassium
    • Walz W. Role of astrocytes in the clearance of excess extracellular potassium. Neurochemistry International 2000, 36(4-5):291-300.
    • (2000) Neurochemistry International , vol.36 , Issue.4-5 , pp. 291-300
    • Walz, W.1
  • 198
    • 66149107054 scopus 로고    scopus 로고
    • Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR
    • Wang C.Y., Kim H.H., Hiroi Y., Sawada N., Salomone S., Benjamin L.E., et al. Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. Science Signaling 2009, 2(62):11. 10.1126/scisignal.2000143.
    • (2009) Science Signaling , vol.2 , Issue.62 , pp. 11
    • Wang, C.Y.1    Kim, H.H.2    Hiroi, Y.3    Sawada, N.4    Salomone, S.5    Benjamin, L.E.6
  • 200
    • 0028167909 scopus 로고
    • Release of alpha-ketoglutarate, malate and succinate from cultured astrocytes: Possible role in amino acid neurotransmitter homeostasis
    • Westergaard N., Sonnewald U., Schousboe A. Release of alpha-ketoglutarate, malate and succinate from cultured astrocytes: Possible role in amino acid neurotransmitter homeostasis. Neuroscience Letters 1994, 176(1):105-109.
    • (1994) Neuroscience Letters , vol.176 , Issue.1 , pp. 105-109
    • Westergaard, N.1    Sonnewald, U.2    Schousboe, A.3
  • 201
    • 84897105601 scopus 로고    scopus 로고
    • Obesity, metabolic syndrome and diabetes mellitus after renal transplantation: Prevention and treatment
    • Wissing K.M., Pipeleers L. Obesity, metabolic syndrome and diabetes mellitus after renal transplantation: Prevention and treatment. Transplantation Reviews (Orlando, Fla.) 2013, 10.1016/j.trre.2013.12.004.
    • (2013) Transplantation Reviews (Orlando, Fla.)
    • Wissing, K.M.1    Pipeleers, L.2
  • 202
    • 17444421921 scopus 로고    scopus 로고
    • Age related changes of various markers of astrocytes in senescence-accelerated mice hippocampus
    • Wu Y., Zhang A.Q., Yew D.T. Age related changes of various markers of astrocytes in senescence-accelerated mice hippocampus. Neurochemistry International 2005, 46(7):565-574. 10.1016/j.neuint.2005.01.002.
    • (2005) Neurochemistry International , vol.46 , Issue.7 , pp. 565-574
    • Wu, Y.1    Zhang, A.Q.2    Yew, D.T.3
  • 204
    • 70449955000 scopus 로고    scopus 로고
    • Sibling history of myocardial infarction or stroke and risk of cardiovascular disease in the elderly: The cardiovascular health study
    • CHS Collaborative Research Group
    • Yanez N.D., Burke G.L., Manolio T., Gardin J.M., Polak J. Sibling history of myocardial infarction or stroke and risk of cardiovascular disease in the elderly: The cardiovascular health study. Annals of Epidemiology 2009, 19(12):858-866. CHS Collaborative Research Group. 10.1016/j.annepidem.2009.07.095.
    • (2009) Annals of Epidemiology , vol.19 , Issue.12 , pp. 858-866
    • Yanez, N.D.1    Burke, G.L.2    Manolio, T.3    Gardin, J.M.4    Polak, J.5
  • 205
    • 0032916578 scopus 로고    scopus 로고
    • Increased interleukin-6 expression by microglia from brain of aged mice
    • Ye S.M., Johnson R.W. Increased interleukin-6 expression by microglia from brain of aged mice. Journal of Neuroimmunology 1999, 93(1-2):139-148.
    • (1999) Journal of Neuroimmunology , vol.93 , Issue.1-2 , pp. 139-148
    • Ye, S.M.1    Johnson, R.W.2
  • 206
    • 84888988758 scopus 로고    scopus 로고
    • Early and continuous neurologic improvements after intravenous thrombolysis are strong predictors of favorable long-term outcomes in acute ischemic stroke
    • Yeo L.L., Paliwal P., Teoh H.L., Seet R.C., Chan B.P., Wakerley B., et al. Early and continuous neurologic improvements after intravenous thrombolysis are strong predictors of favorable long-term outcomes in acute ischemic stroke. Journal of Stroke and Cerebrovascular Diseases 2013, 22(8):e590-e596. 10.1016/j.jstrokecerebrovasdis.2013.07.024.
    • (2013) Journal of Stroke and Cerebrovascular Diseases , vol.22 , Issue.8 , pp. e590-e596
    • Yeo, L.L.1    Paliwal, P.2    Teoh, H.L.3    Seet, R.C.4    Chan, B.P.5    Wakerley, B.6
  • 207
    • 84903184764 scopus 로고    scopus 로고
    • Effects of pioglitazone on macrovascular events in patients with type 2 diabetes mellitus at high risk of stroke: The PROFIT-J study
    • Yoshii H., Onuma T., Yamazaki T., Watada H., Matsuhisa M., Matsumoto M., et al. Effects of pioglitazone on macrovascular events in patients with type 2 diabetes mellitus at high risk of stroke: The PROFIT-J study. Journal of Atherosclerosis and Thrombosis 2014, 21:563-573.
    • (2014) Journal of Atherosclerosis and Thrombosis , vol.21 , pp. 563-573
    • Yoshii, H.1    Onuma, T.2    Yamazaki, T.3    Watada, H.4    Matsuhisa, M.5    Matsumoto, M.6
  • 208
    • 79960622733 scopus 로고    scopus 로고
    • Glucocorticoid regulation of astrocytic fate and function
    • Yu S., Yang S., Holsboer F., Sousa N., Almeida O.F. Glucocorticoid regulation of astrocytic fate and function. PLoS One 2011, 6(7):e22419. 10.1371/journal.pone.0022419.
    • (2011) PLoS One , vol.6 , Issue.7 , pp. e22419
    • Yu, S.1    Yang, S.2    Holsboer, F.3    Sousa, N.4    Almeida, O.F.5
  • 210
    • 84896100297 scopus 로고    scopus 로고
    • Phospholipid transfer protein (PLTP) deficiency impaired blood-brain barrier integrity by increasing cerebrovascular oxidative stress
    • Zhou T., He Q., Tong Y., Zhan R., Xu F., Fan D., et al. Phospholipid transfer protein (PLTP) deficiency impaired blood-brain barrier integrity by increasing cerebrovascular oxidative stress. Biochemical and Biophysical Research Communications 2014, 445(2):352-356. 10.1016/j.bbrc.2014.01.194.
    • (2014) Biochemical and Biophysical Research Communications , vol.445 , Issue.2 , pp. 352-356
    • Zhou, T.1    He, Q.2    Tong, Y.3    Zhan, R.4    Xu, F.5    Fan, D.6
  • 211
    • 3042670686 scopus 로고    scopus 로고
    • Proliferative response of corneal endothelial cells from young and older donors
    • Zhu C., Joyce N.C. Proliferative response of corneal endothelial cells from young and older donors. Investigative Ophthalmology & Visual Science 2004, 45(6):1743-1751.
    • (2004) Investigative Ophthalmology & Visual Science , vol.45 , Issue.6 , pp. 1743-1751
    • Zhu, C.1    Joyce, N.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.