Selective MCA occlusion: A precise embolic stroke model

Journal of Neuroscience Methods

Volumn 154, Issue 1-2, 2006, Pages 233-238

  DiNapoli, Vincent A ^a   Rosen, Charles L ^a   Nagamine, Tomoaki ^b   Crocco, Todd ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Aging; Cerebral ischemia; Focal embolic ischemia; Stroke model

Indexed keywords

ALTEPLASE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CATHETER; ARTICLE; ARTIFICIAL EMBOLISM; BLOOD CLOTTING; BRAIN INFARCTION SIZE; BRAIN PERFUSION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISEASE SEVERITY; EXAMINATION; FEMALE; FUNCTIONAL DISEASE; LASER DOPPLER FLOWMETRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; RATING SCALE; RECANALIZATION; RELIABILITY; REPRODUCIBILITY; SCORING SYSTEM; SURVIVAL TIME; TREATMENT FAILURE;

AGING; ANIMALS; BLOOD PRESSURE; BRAIN ISCHEMIA; CARBON DIOXIDE; CAROTID ARTERIES; CEREBRAL INFARCTION; CEREBROVASCULAR ACCIDENT; DISEASE MODELS, ANIMAL; FEMALE; HEMATOCRIT; HYDROGEN-ION CONCENTRATION; INTRACRANIAL EMBOLISM; MIDDLE CEREBRAL ARTERY; PLASMINOGEN ACTIVATORS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; THROMBOLYTIC THERAPY; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 33744527080     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2005.12.026     Document Type: Article

References (17)

1. Albers G.W. Antithrombotic agents in cerebral ischemia. Am J Cardiol 75 (1995) 34B-38B
2. Alkayed N.J., Murphy S.J., Traystman R.J., Hurn P.D., and Miller V.M. Neuroprotective effects of female gonadal steroids in reproductively senescent female rats. Stroke 31 (2000) 161-168
3. Anderson J.M., Hubbard B.M., Coghill G.R., and Slidders W. The effect of advanced old age on the neurone content of the cerebral cortex. Observations with an automatic image analyser point counting method. J Neurol Sci 58 (1983) 235-246
4. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., and Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17 (1986) 472-476
5. Chen J., Li Y., Wang L., Zhang Z., Lu D., Lu M., et al. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 32 (2001) 1005-1011
6. Germano A.F., Dixon C.E., d'Avella D., Hayes R.L., and Tomasello F. Behavioral deficits following experimental subarachnoid hemorrhage in the rat. J Neurotrauma 11 (1994) 345-353
7. Ginsberg M.D., and Busto R. Rodent models of cerebral ischemia. Stroke 20 (1989) 1627-1642
8. Kudo M., Aoyama A., Ichimori S., and Fukunaga N. An animal model of cerebral infarction. Homologous blood clot emboli in rats. Stroke 13 (1982) 505-508
9. Molinari G.F. Why model strokes?. Stroke 19 (1988) 1195-1197
10. Overgaard K., Sereghy T., Boysen G., Pedersen H., Hoyer S., and Diemer N.H. A rat model of reproducible cerebral infarction using thrombotic blood clot emboli. J Cereb Blood Flow Metab 12 (1992) 484-490
11. Rosen C.L., Dinapoli V.A., Nagamine T., and Crocco T. Influence of age on stroke outcome following transient focal ischemia. J Neurosurg 103 (2005) 687-694
12. Seyfried D., Han Y., Lu D., Chen J., Bydon A., and Chopp M. Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats. J Neurosurg 101 (2004) 104-107
13. Sloan M.A. Thrombolysis and stroke. Past and future. Arch Neurol 44 (1987) 748-768
14. Tejima E., Katayama Y., Suzuki Y., Kano T., and Lo E.H. Hemorrhagic transformation after fibrinolysis with tissue plasminogen activator: evaluation of role of hypertension with rat thromboembolic stroke model. Stroke 32 (2001) 1336-1340
15. Yang Y., Shuaib A., and Li Q. Quantification of infarct size on focal cerebral ischemia model of rats using a simple and economical method. J Neurosci Methods 84 (1998) 9-16
16. Zhang R.L., Chopp M., Zhang Z.G., Jiang Q., and Ewing J.R. A rat model of focal embolic cerebral ischemia. Brain Res 766 (1997) 83-92
17. Zhang L., Zhang R.L., Wang Y., Zhang C., Zhang Z.G., Meng H., et al. Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor. Stroke 36 (2005) 847-852