Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat

Neuroscience

Volumn 170, Issue 2, 2010, Pages 633-644

  DiNapoli, V A ^a   Benkovic, S A ^b   Li, X ^a   Kelly, K A ^c   Miller, D B ^b   Rosen, C L ^a   Huber, J D ^c   O'Callaghan, J P ^b  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Astrocyte; Interleukin 6; Microglia; Middle cerebral artery occlusion; Neuroinflammation; Suppressor of cytokine signaling 3

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; RNA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ADULT ANIMAL; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN ISCHEMIA; CONTROLLED STUDY; DNA SYNTHESIS; FEMALE; GLIA; IMMUNOHISTOCHEMISTRY; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION;

AGE FACTORS; ANIMALS; ASTROCYTES; BRAIN; BRAIN ISCHEMIA; CEREBRAL CORTEX; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; INFARCTION, MIDDLE CEREBRAL ARTERY; MICROGLIA; NERVE DEGENERATION; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STROKE; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 77956184903     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.07.011     Document Type: Article

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