-
1
-
-
2642563899
-
Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines
-
DOI 10.1097/00041433-200406000-00009
-
Ruan H, Lodish HF (2004) Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines. Curr Opin Lipidol 15:297-302. (Pubitemid 38716562)
-
(2004)
Current Opinion in Lipidology
, vol.15
, Issue.3
, pp. 297-302
-
-
Ruan, H.1
Lodish, H.F.2
-
2
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444:860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
3
-
-
1642633752
-
Inflamed about obesity
-
DOI 10.1038/nm0204-126
-
Lehrke M, Lazar MA (2004) Inflamed about obesity. Nat Med 10:126-127. (Pubitemid 38524875)
-
(2004)
Nature Medicine
, vol.10
, Issue.2
, pp. 126-127
-
-
Lehrke, M.1
Lazar, M.A.2
-
4
-
-
64149101055
-
Getting away from glucose: Fanning the flames of obesity-induced inflammation
-
Shoelson SE, Goldfine AB (2009) Getting away from glucose: Fanning the flames of obesity-induced inflammation. Nat Med 15:373-374.
-
(2009)
Nat Med
, vol.15
, pp. 373-374
-
-
Shoelson, S.E.1
Goldfine, A.B.2
-
5
-
-
69249211226
-
NF?B-mediated metabolic inflammation in peripheral tissues versus central nervous system
-
Cai D (2009) NF?B-mediated metabolic inflammation in peripheral tissues versus central nervous system. Cell Cycle 8:2542-2548.
-
(2009)
Cell Cycle
, vol.8
, pp. 2542-2548
-
-
Cai, D.1
-
6
-
-
51349156218
-
Insulin sensitivity: Modulation by nutrients and inflammation
-
Schenk S, Saberi M, Olefsky JM (2008) Insulin sensitivity: Modulation by nutrients and inflammation. J Clin Invest 118:2992-3002.
-
(2008)
J Clin Invest
, vol.118
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
7
-
-
33645074450
-
Etiology of insulin resistance
-
Petersen KF, Shulman GI (2006) Etiology of insulin resistance.AmJ Med 119 (5 Suppl 1): S10-S16.
-
(2006)
AmJ Med
, vol.119
, Issue.5 SUPPL. 1
-
-
Petersen, K.F.1
Shulman, G.I.2
-
9
-
-
33646885699
-
Energy metabolism and oxidative stress: Impact on the metabolic syndrome and the aging process
-
DOI 10.1385/ENDO:29:1:27
-
Frisard M, Ravussin E (2006) Energy metabolism and oxidative stress: Impact on the metabolic syndrome and the aging process. Endocrine 29:27-32. (Pubitemid 43780344)
-
(2006)
Endocrine
, vol.29
, Issue.1
, pp. 27-32
-
-
Frisard, M.1
Ravussin, E.2
-
10
-
-
43549105167
-
The unfolded protein response: A pathway that links insulin demand with β-cell failure and diabetes
-
DOI 10.1210/er.2007-0039
-
Scheuner D, Kaufman RJ (2008) The unfolded protein response: A pathway that links insulin demand with β-cell failure and diabetes. Endocr Rev 29:317-333. (Pubitemid 351679702)
-
(2008)
Endocrine Reviews
, vol.29
, Issue.3
, pp. 317-333
-
-
Scheuner, D.1
Kaufman, R.J.2
-
11
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS (2010) Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140:900-917.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
12
-
-
70350459324
-
From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis
-
Glimcher LH, Lee AH (2009) From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis. Ann N Y Acad Sci 1173 (Suppl 1):E2-E9.
-
(2009)
Ann N Y Acad Sci
, vol.1173
, Issue.SUPPL. 1
-
-
Glimcher, L.H.1
Lee, A.H.2
-
13
-
-
67649450485
-
Translation attenuation through eIF2? Phosphorylation prevents oxidative stress and maintains the differentiated state in β cells
-
Back SH, et al. (2009) Translation attenuation through eIF2? phosphorylation prevents oxidative stress and maintains the differentiated state in β cells. Cell Metab 10:13-26.
-
(2009)
Cell Metab
, vol.10
, pp. 13-26
-
-
Back, S.H.1
-
14
-
-
34547638958
-
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
-
Huang CJ, et al. (2007) High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes 56:2016-2027.
-
(2007)
Diabetes
, vol.56
, pp. 2016-2027
-
-
Huang, C.J.1
-
15
-
-
73149099638
-
Pdx1 (MODY4) regulates pancreatic? Cell susceptibility to ER stress
-
Sachdeva MM, et al. (2009) Pdx1 (MODY4) regulates pancreatic ? cell susceptibility to ER stress. Proc Natl Acad Sci USA 106:19090-19095.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19090-19095
-
-
Sachdeva, M.M.1
-
16
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan U, et al. (2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313:1137-1140. (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
17
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
DOI 10.1126/science.1103160
-
Ozcan U, et al. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306:457-461. (Pubitemid 39372439)
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.-H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
18
-
-
67749135249
-
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
-
Wang Y, Vera L, Fischer WH, Montminy M (2009) The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature 460:534-537.
-
(2009)
Nature
, vol.460
, pp. 534-537
-
-
Wang, Y.1
Vera, L.2
Fischer, W.H.3
Montminy, M.4
-
19
-
-
52949096557
-
Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
-
Zhang X, et al. (2008) Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity. Cell 135:61-73.
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
-
20
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
Ozcan L, et al. (2009) Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab 9:35-51.
-
(2009)
Cell Metab
, vol.9
, pp. 35-51
-
-
Ozcan, L.1
-
22
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
DOI 10.1038/nature05026, PII NATURE05026
-
Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW (2006) Central nervous system control of food intake and body weight. Nature 443:289-295. (Pubitemid 44435142)
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
23
-
-
43549114292
-
Mechanisms of leptin action and leptin resistance
-
DOI 10.1146/annurev.physiol.70.113006.100707
-
Myers MG, Cowley MA, Münzberg H (2008) Mechanisms of leptin action and leptin resistance. Annu Rev Physiol 70:537-556. (Pubitemid 351738191)
-
(2008)
Annual Review of Physiology
, vol.70
, pp. 537-556
-
-
Myers, M.G.1
Cowley, M.A.2
Munzberg, H.3
-
24
-
-
65249162834
-
Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver
-
Klieverik LP, et al. (2009) Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver. Proc Natl Acad Sci USA 106:5966-5971.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5966-5971
-
-
Klieverik, L.P.1
-
25
-
-
17844379717
-
Hypothalamic K(ATP) channels control hepatic glucose production
-
Pocai A, et al. (2005) Hypothalamic K(ATP) channels control hepatic glucose production. Nature 434:1026-1031.
-
(2005)
Nature
, vol.434
, pp. 1026-1031
-
-
Pocai, A.1
-
26
-
-
16244388931
-
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
-
DOI 10.1038/nm1201
-
Lam TK, et al. (2005) Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis. Nat Med 11:320-327. (Pubitemid 40460561)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 320-327
-
-
Lam, T.K.T.1
Pocai, A.2
Gutierrez-Juarez, R.3
Obici, S.4
Bryan, J.5
Aguilar-Bryan, L.6
Schwartz, G.J.7
Rossetti, L.8
-
27
-
-
0036913187
-
Hypothalamic insulin signaling is required for inhibition of glucose production
-
DOI 10.1038/nm798
-
Obici S, Zhang BB, Karkanias G, Rossetti L (2002) Hypothalamic insulin signaling is required for inhibition of glucose production. Nat Med 8:1376-1382. (Pubitemid 36019422)
-
(2002)
Nature Medicine
, vol.8
, Issue.12
, pp. 1376-1382
-
-
Obici, S.1
Zhang, B.B.2
Karkanias, G.3
Rossetti, L.4
-
28
-
-
34548362074
-
Hypothalamic leptin regulation of energy homeostasis and glucose metabolism
-
Morton GJ (2007) Hypothalamic leptin regulation of energy homeostasis and glucose metabolism. J Physiol 583:437-443.
-
(2007)
J Physiol
, vol.583
, pp. 437-443
-
-
Morton, G.J.1
-
29
-
-
33645071314
-
Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes
-
Gelling RW, et al. (2006) Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes. Cell Metab 3:67-73.
-
(2006)
Cell Metab
, vol.3
, pp. 67-73
-
-
Gelling, R.W.1
-
30
-
-
70349627027
-
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
-
Hetz C, et al. (2009) XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev 23:2294-2306.
-
(2009)
Genes Dev
, vol.23
, pp. 2294-2306
-
-
Hetz, C.1
-
31
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
DOI 10.1016/S1097-2765(01)00265-9
-
Scheuner D, et al. (2001) Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 7:1165-1176. (Pubitemid 32607351)
-
(2001)
Molecular Cell
, vol.7
, Issue.6
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
32
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival
-
DOI 10.1016/S1097-2765(01)00264-7
-
Harding HP, et al. (2001) Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell 7: 1153-1163. (Pubitemid 32607350)
-
(2001)
Molecular Cell
, vol.7
, Issue.6
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
Sabatini, D.D.7
Ron, D.8
-
33
-
-
4143087106
-
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
-
Chae HJ, et al. (2004) BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell 15:355-366.
-
(2004)
Mol Cell
, vol.15
, pp. 355-366
-
-
Chae, H.J.1
-
34
-
-
70349696241
-
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways
-
Timmins JM, et al. (2009) Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest 119:2925-2941.
-
(2009)
J Clin Invest
, vol.119
, pp. 2925-2941
-
-
Timmins, J.M.1
-
35
-
-
0037058574
-
IPK
-
DOI 10.1073/pnas.252341799
-
Yan W, et al. (2002) Control of PERK eIF2α kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. Proc Natl Acad Sci USA 99: 15920-15925. (Pubitemid 35462724)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 15920-15925
-
-
Yan, W.1
Frank, C.L.2
Korth, M.J.3
Sopher, B.L.4
Novoa, I.5
Ron, D.6
Katze, M.G.7
-
36
-
-
0027772352
-
Prazosin, diuretics, and glucose intolerance
-
Ross H, Moser M (1993) Prazosin, diuretics, and glucose intolerance. Ann Intern Med 119:859-860.
-
(1993)
Ann Intern Med
, vol.119
, pp. 859-860
-
-
Ross, H.1
Moser, M.2
-
37
-
-
0025868129
-
α-Blocker therapy of hypertension: An unfulfilled promise
-
Khoury AF, Kaplan NM (1991) α-Blocker therapy of hypertension: An unfulfilled promise. JAMA 266:394-398.
-
(1991)
JAMA
, vol.266
, pp. 394-398
-
-
Khoury, A.F.1
Kaplan, N.M.2
-
38
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon F, Chen X, Lee AH, Glimcher LH (2010) TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol 11: 411-418.
-
(2010)
Nat Immunol
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
39
-
-
5444262078
-
IKKβ/NF-κB activation causes severe muscle wasting in mice
-
DOI 10.1016/j.cell.2004.09.027, PII S0092867404009006
-
Cai D, et al. (2004) IKKβ/NF-κB activation causes severe muscle wasting in mice. Cell 119:285-298. (Pubitemid 39360909)
-
(2004)
Cell
, vol.119
, Issue.2
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa Jr., N.E.3
Melendez, P.A.4
Oh, B.-C.5
Lidov, H.G.W.6
Hasselgren, P.-O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
40
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
-
DOI 10.1038/nm1166
-
Cai D, et al. (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB. Nat Med 11:183-190. (Pubitemid 40321354)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
41
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
-
DOI 10.1038/47513
-
Nakagawa T, et al. (2000) Caspase-12 mediates endoplasmic-reticulum- specific apoptosis and cytotoxicity by amyloid-β. Nature 403:98-103. (Pubitemid 30038529)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
42
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
DOI 10.1038/sj.cdd.4401373
-
Oyadomari S, Mori M (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11:381-389. (Pubitemid 38489416)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
43
-
-
0842309993
-
Increased Risk of Type 2 Diabetes in Alzheimer Disease
-
DOI 10.2337/diabetes.53.2.474
-
Janson J, et al. (2004) Increased risk of type 2 diabetes in Alzheimer disease. Diabetes 53:474-481. (Pubitemid 38174565)
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 474-481
-
-
Janson, J.1
Laedtke, T.2
Parisi, J.E.3
O'Brien, P.4
Petersen, R.C.5
Butler, P.C.6
-
44
-
-
4444318357
-
ER chaperone functions during normal and stress conditions
-
DOI 10.1016/j.jchemneu.2003.08.007, PII S0891061804000031
-
Ma Y, Hendershot LM (2004) ER chaperone functions during normal and stress conditions. J Chem Neuroanat 28:51-65. (Pubitemid 39195252)
-
(2004)
Journal of Chemical Neuroanatomy
, vol.28
, Issue.1-2
, pp. 51-65
-
-
Ma, Y.1
Hendershot, L.M.2
-
45
-
-
6344284383
-
Acute and chronic stress influence blood pressure variability in mice
-
DOI 10.1016/j.physbeh.2004.08.004, PII S0031938404003300
-
Farah VM, Joaquim LF, Bernatova I, Morris M (2004) Acute and chronic stress influence blood pressure variability in mice. Physiol Behav 83:135-142. (Pubitemid 39387702)
-
(2004)
Physiology and Behavior
, vol.83
, Issue.1 SPEC. ISS
, pp. 135-142
-
-
Farah, V.M.A.1
Joaquim, L.F.2
Bernatova, I.3
Morris, M.4
|