Glucocorticoid regulation of astrocytic fate and function

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Yu, Shuang ^a   Yang, Silei ^a   Holsboer, Florian ^a   Sousa, Nuno ^b   Almeida, Osborne F X ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF MINHO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GLUCOCORTICOID; REACTIVE OXYGEN METABOLITE; CYTOKINE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL FATE; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; GROWTH INHIBITION; HIPPOCAMPUS; HORMONAL REGULATION; NERVE CELL CULTURE; NEURAL STEM CELL; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT; AGING; ANIMAL; CELL CULTURE; CELL LINEAGE; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PHENOTYPE;

RATTUS;

AGING; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ASTROCYTES; CASPASE 3; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYTOKINES; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOCORTICOIDS; HIPPOCAMPUS; NEUROGENESIS; NEURONS; PHENOTYPE; RATS; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER;

EID: 79960622733     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022419     Document Type: Article

References (66)

1. de Kloet ER, Joels M, Holsboer F, (2005) Stress and the brain: from adaptation to disease. Nat Rev Neurosci 6: 463-475.
2. Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, et al. (2006) Do corticosteroids damage the brain? J Neuroendocrinol 18: 393-411.
3. Sandi C, (2004) Stress, cognitive impairment and cell adhesion molecules. Nat Rev Neurosci 5: 917-930.
4. Marinelli M, Piazza PV, (2002) Interaction between glucocorticoid hormones, stress and psychostimulant drugs. Eur J Neurosci 16: 387-394.
5. Goel N, Bale TL, (2009) Examining the intersection of sex and stress in modelling neuropsychiatric disorders. J Neuroendocrinol 21: 415-420.
6. Meyer U, Feldon J, (2010) Epidemiology-driven neurodevelopmental animal models of schizophrenia. Prog Neurobiol 90: 285-326.
7. Lupien SJ, Nair NP, Briere S, Maheu F, Tu MT, et al. (1999) Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life. Rev Neurosci 10: 117-139.
8. Sheline YI, (2000) 3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity. Biol Psychiatry 48: 791-800.
9. Starkman MN, Giordani B, Gebarski SS, Schteingart DE, (2003) Improvement in learning associated with increase in hippocampal formation volume. Biol Psychiatry 53: 233-238.
10. Cerqueira JJ, Pêgo JM, Taipa R, Bessa JM, Almeida OFX, et al. (2005) Morphological correlates of corticosteroid-induced changes in prefrontal cortex-dependent behaviors. J Neurosci 25: 7792-7800.
11. Cerqueira JJ, Mailliet F, Almeida OFX, Jay TM, Sousa N, (2007) The prefrontal cortex as a key target of the maladaptive response to stress. J Neurosci 27: 2781-2787.
12. Pêgo JM, Morgado P, Pinto LG, Cerqueira JJ, Almeida OFX, et al. (2008) Dissociation of the morphological correlates of stress-induced anxiety and fear. Eur J Neurosci 27: 1503-1516.
13. Leão P, Sousa JC, Oliveira M, Silva R, Almeida OFX, et al. (2007) Programming effects of antenatal dexamethasone in the developing mesolimbic pathways. Synapse 61: 40-49.
14. Schubert MI, Kalisch R, Sotiropoulos I, Catania C, Sousa N, et al. (2008) Effects of altered corticosteroid milieu on rat hippocampal neurochemistry and structure--an in vivo magnetic resonance spectroscopy and imaging study. J Psychiatr Res 42: 902-912.
15. Sousa N, Cerqueira JJ, Almeida OFX, (2008) Corticosteroid receptors and neuroplasticity. Brain Res Rev 57: 561-570.
16. Müller MB, Lucassen PJ, Yassouridis A, Hoogendijk WJ, Holsboer F, et al. (2001) Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus. Eur J Neurosci 14: 1603-1612.
17. Rajkowska G, Miguel-Hidalgo JJ, Wei J, Dilley G, Pittman SD, et al. (1999) Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol Psychiatry 45: 1085-1098.
18. Bowley MP, Drevets WC, Ongür D, Price JL, (2002) Low glial numbers in the amygdala in major depressive disorder. Biol Psychiatry 52: 404-412.
19. Banasr M, Duman RS, (2008) Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors. Biol Psychiatry 64: 863-870.
20. Czéh B, Simon M, Schmelting B, Hiemke C, Fuchs E, (2006) Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology 31: 1616-1626.
21. Banasr M, Chowdhury GM, Terwilliger R, Newton SS, Duman RS, et al. (2010) Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole. Mol Psychiatry 15: 501-511.
22. Yu S, Patchev AV, Wu Y, Lu J, Holsboer F, et al. (2010) Depletion of the neural precursor cell pool by glucocorticoids. Ann Neurol 67: 21-30.
23. Hassan AH, von Rosenstiel P, Patchev VK, Holsboer F, Almeida OFX, (1996) Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethasone and the protective role of corticosterone. Exp Neurol 140: 43-52.
24. Almeida OFX, Condé GL, Crochemore C, Demeneix BA, Fischer D, et al. (2000) Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate. FASEB J 14: 779-790.
25. Lu J, Goula D, Sousa N, Almeida OFX, (2003) Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors. Neuroscience 121: 123-131.
26. Crochemore C, Lu J, Wu Y, Liposits Z, Sousa N, et al. (2005) Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation. Mol Psychiatry 10: 790-798.
27. Wang S, Wu H, Jiang J, Delohery TM, Isdell F, et al. (1998) Isolation of neuronal precursors by sorting embryonic forebrain transfected with GFP regulated by the T alpha 1 tubulin promoter. Nat Biotechnol 16: 196-201.
28. Roy NS, Wang S, Jiang L, Kang J, Benraiss A, et al. (2000) In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nat Med 6: 271-277.
29. Nolte C, Matyash M, Pivneva T, Schipke CG, Ohlemeyer C, et al. (2001) GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue. Glia 33: 72-86.
30. Crochemore C, Michaelidis TM, Fischer D, Loeffler JP, Almeida OFX, (2002) Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation. FASEB J 16: 761-770.
31. Galderisi U, Jori FP, Giordano A, (2003) Cell cycle regulation and neural differentiation. Oncogene 22: 5208-5219.
32. Samejima K, Tone S, Earnshaw WC, (2001) CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis. J Biol Chem 276: 45427-45432.
33. Oberhammer F, Wilson JW, Dive C, Morris ID, Hickman JA, et al. (1993) Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12: 3679-3684.
34. Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ, (2001) ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 276: 42462-42467.
35. Sionov RV, Cohen O, Kfir S, Zilberman Y, Yefenof E, (2006) Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis. J Exp Med 203: 189-201.
36. McIntosh LJ, Sapolsky RM, (1996) Glucocorticoids increase the accumulation of reactive oxygen species and enhance adriamycin-induced toxicity in neuronal culture. Exp Neurol 141: 201-206.
37. Son GH, Geum D, Chung S, Park E, Lee KH, et al. (2005) A protective role of 27-kDa heat shock protein in glucocorticoid-evoked apoptotic cell death of hippocampal progenitor cells. Biochem Biophys Res Commun 338: 1751-1758.
38. Orrenius S, Gogvadze V, Zhivotovsky B, (2007) Mitochondrial oxidative stress: implications for cell death. Annu Rev Pharmacol Toxicol 47: 143-183.
39. Fellin T, (2009) Communication between neurons and astrocytes: relevance to the modulation of synaptic and network activity. J Neurochem 108: 533-544.
40. Bohn MC, O'Banion MK, Young DA, Giuliano R, Hussain S, et al. (1994) In vitro studies of glucocorticoid effects on neurons and astrocytes. Ann N Y Acad Sci 746: 243-258.
41. Nichols NR, Zieba M, Bye N, (2001) Do glucocorticoids contribute to brain aging? Brain Res Brain Res Rev 37: 273-286.
42. Maragakis NJ, Rothstein JD, (2006) Mechanisms of Disease: astrocytes in neurodegenerative disease. Nat Clin Pract Neurol 2: 679-689.
43. Platel JC, Dave KA, Gordon V, Lacar B, Rubio ME, et al. (2010) NMDA receptors activated by subventricular zone astrocytic glutamate are critical for neuroblast survival prior to entering a synaptic network. Neuron 65: 859-872.
44. Cabras S, Saba F, Reali C, Scorciapino ML, Sirigu A, et al. (2010) Antidepressant imipramine induces human astrocytes to differentiate into cells with neuronal phenotype. Int J Neuropsychopharmacol 13: 603-615.
45. Stockmeier CA, Mahajan GJ, Konick LC, Overholser JC, Jurjus GJ, et al. (2004) Cellular changes in the postmortem hippocampus in major depression. Biol Psychiatry 56: 640-650.
46. Haynes LE, Lendon CL, Barber DJ, Mitchell IJ, (2003) 17 Beta-oestradiol attenuates dexamethasone-induced lethal and sublethal neuronal damage in the striatum and hippocampus. Neuroscience 120: 799-806.
47. Collins JA, Schandi CA, Young KK, Vesely J, Willingham MC, (1997) Major DNA fragmentation is a late event in apoptosis. J Histochem Cytochem 45: 923-934.
48. Garrido C, Galluzzi L, Brunet M, Puig PE, Didelot C, et al. (2006) Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 13: 1423-1433.
49. Danial NN, Korsmeyer SJ, (2004) Cell death: critical control points. Cell 116: 205-219.
50. Fernando P, Megeney LA, (2007) Is caspase-dependent apoptosis only cell differentiation taken to the extreme? FASEB J 21: 8-17.
51. Rohn TT, Cusack SM, Kessinger SR, Oxford JT, (2004) Caspase activation independent of cell death is required for proper cell dispersal and correct morphology in PC12 cells. Exp Cell Res 295: 215-225.
52. Fernando P, Brunette S, Megeney LA, (2005) Neural stem cell differentiation is dependent upon endogenous caspase 3 activity. FASEB J 19: 1671-1673.
53. Okuyama R, Nguyen BC, Talora C, Ogawa E, Tommasi di Vignano A, et al. (2004) High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Dev Cell 6: 551-562.
54. Zandy AJ, Lakhani S, Zheng T, Flavell RA, Bassnett S, (2005) Role of the executioner caspases during lens development. J Biol Chem 280: 30263-30272.
55. Zermati Y, Garrido C, Amsellem S, Fishelson S, Bouscary D, et al. (2001) Caspase activation is required for terminal erythroid differentiation. J Exp Med 193: 247-254.
56. Fernando P, Kelly JF, Balazsi K, Slack RS, Megeney LA, (2002) Caspase 3 activity is required for skeletal muscle differentiation. Proc Natl Acad Sci U S A 99: 11025-11030.
57. Miura M, Chen XD, Allen MR, Bi Y, Gronthos S, et al. (2004) A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. J Clin Invest 114: 1704-1713.
58. Acarin L, Villapol S, Faiz M, Rohn TT, Castellano B, et al. (2007) Caspase-3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodeling but not with cell death or proliferation. Glia 55: 954-965.
59. Yu S, Holsboer F, Almeida OF, (2008) Neuronal actions of glucocorticoids: focus on depression. J Steroid Biochem Mol Biol 108: 300-309.
60. Sundberg M, Savola S, Hienola A, Korhonen L, Lindholm D, (2006) Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1. J Neurosci 26: 5402-5410.
61. Wennstroem M, Hellsten J, Ekstrand J, Lindgren H, Tingstroem A, (2006) Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures. Biol Psychiatry 59: 178-186.
62. Vardimon L, Ben-Dror I, Avisar N, Oren A, Shiftan L, (1999) Glucocorticoid control of glial gene expression. J Neurobiol 40: 513-527.
63. Zschocke J, Bayatti N, Clement AM, Witan H, Figiel M, et al. (2005) Differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions. J Biol Chem 280: 34924-34932.
64. Gottschall PE, Koves K, Mizuno K, Tatsuno I, Arimura A, (1991) Glucocorticoid upregulation of interleukin 1 receptor expression in a glioblastoma cell line. Am J Physiol 261: E362-E368.
65. Mirescu C, Gould E, (2006) Stress and adult neurogenesis. Hippocampus 16: 233-238.
66. Lu J, Wu Y, Sousa N, Almeida OFX, (2005) SMAD pathway mediation of BDNF and TGF beta 2 regulation of proliferation and differentiation of hippocampal granule neurons. Development 132: 3231-3242.