-
1
-
-
20444427991
-
The anticoagulant protein C pathway
-
Dahlback B, Villoutreix BO. The anticoagulant protein C pathway. FEBS Lett 2005; 579: 3310-16.
-
(2005)
FEBS Lett
, vol.579
, pp. 3310-3316
-
-
Dahlback, B.1
Villoutreix, B.O.2
-
3
-
-
13244253704
-
Haplotypes of the EPCR gene, plasma sEPCR levels and the risk of deep venous thrombosis
-
Uitte de Willige S, Van Marion V, Rosendaal FR, Vos HL, de Visser MC, Bertina RM. Haplotypes of the EPCR gene, plasma sEPCR levels and the risk of deep venous thrombosis. J Thromb Haemost 2004; 2: 1305-10.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 1305-1330
-
-
Uitte de Willige, S.1
Van Marion, V.2
Rosendaal, F.R.3
Vos, H.L.4
de Visser, M.C.5
Bertina, R.M.6
-
4
-
-
0842307339
-
A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis
-
Saposnik B, Reny JL, Gaussem P, Emmerich J, Aiach M, Gandrille S. A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis. Blood 2004; 103: 1311-18.
-
(2004)
Blood
, vol.103
, pp. 1311-1318
-
-
Saposnik, B.1
Reny, J.L.2
Gaussem, P.3
Emmerich, J.4
Aiach, M.5
Gandrille, S.6
-
5
-
-
0034603799
-
Genetic determinants of hemostasis phenotypes in Spanish families
-
Souto JC, Almasy L, Borrell M, Gari M, Martinez E, Mateo J, Stone WH, Blangero J, Fontcuberta J. Genetic determinants of hemostasis phenotypes in Spanish families. Circulation 2000; 101: 1546-51.
-
(2000)
Circulation
, vol.101
, pp. 1546-1551
-
-
Souto, J.C.1
Almasy, L.2
Borrell, M.3
Gari, M.4
Martinez, E.5
Mateo, J.6
Stone, W.H.7
Blangero, J.8
Fontcuberta, J.9
-
6
-
-
4644245436
-
Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family
-
Vossen CY, Hasstedt SJ, Rosendaal FR, Callas PW, Bauer KA, Broze GJ, Hoogendoorn H, Long GL, Scott BT, Bovill EG. Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family. J Thromb Haemost 2004; 2: 242-7.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 242-247
-
-
Vossen, C.Y.1
Hasstedt, S.J.2
Rosendaal, F.R.3
Callas, P.W.4
Bauer, K.A.5
Broze, G.J.6
Hoogendoorn, H.7
Long, G.L.8
Scott, B.T.9
Bovill, E.G.10
-
7
-
-
0037342687
-
Genetic Analysis of Idiopathic Thrombophilia project. A quantitative trait locus influencing free plasma protein S levels on human chromosome 1q: Results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) project
-
Almasy L, Soria JM, Souto JC, Coll I, Bacq D, Faure A, Mateo J, Borrell M, Muñoz X, Sala N, Stone WH, Lathrop M, Fontcuberta J, Blangero J; Genetic Analysis of Idiopathic Thrombophilia project. A quantitative trait locus influencing free plasma protein S levels on human chromosome 1q: Results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) project. Arterioscler Thromb Vasc Biol 2003; 23: 508-11.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 508-511
-
-
Almasy, L.1
Soria, J.M.2
Souto, J.C.3
Coll, I.4
Bacq, D.5
Faure, A.6
Mateo, J.7
Borrell, M.8
Muñoz, X.9
Sala, N.10
Stone, W.H.11
Lathrop, M.12
Fontcuberta, J.13
Blangero, J.14
-
8
-
-
3042853035
-
Protein C levels are regulated by a quantitative trait locus on chromosome 16: Results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project
-
Buil A, Soria JM, Souto JC, Almasy L, Lathrop M, Blangero J, Fontcuberta J. Protein C levels are regulated by a quantitative trait locus on chromosome 16: Results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project. Arterioscler Thromb Vasc Biol 2004; 24: 1321-5.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1321-1325
-
-
Buil, A.1
Soria, J.M.2
Souto, J.C.3
Almasy, L.4
Lathrop, M.5
Blangero, J.6
Fontcuberta, J.7
-
9
-
-
0028968010
-
Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk
-
Spek CA, Koster T, Rosendaal FR, Bertina RM, Reitsma PH. Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk. Arterioscler Thromb Vasc Biol 1995; 15: 214-18.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 214-218
-
-
Spek, C.A.1
Koster, T.2
Rosendaal, F.R.3
Bertina, R.M.4
Reitsma, P.H.5
-
10
-
-
0032984668
-
Complex association of protein C gene promoter polymorphism with circulating protein C levels and thrombotic risk
-
Aiach M, Nicaud V, Alhenc-Gelas M, Gandrille S, Arnaud E, Amiral J, Guize L, Fiessinger JN, Emmerich J. Complex association of protein C gene promoter polymorphism with circulating protein C levels and thrombotic risk. Arterioscler Thromb Vasc Biol 1999; 19: 1573-6.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 1573-1576
-
-
Aiach, M.1
Nicaud, V.2
Alhenc-Gelas, M.3
Gandrille, S.4
Arnaud, E.5
Amiral, J.6
Guize, L.7
Fiessinger, J.N.8
Emmerich, J.9
-
11
-
-
27644527760
-
EPCR Ser219Gly: Elevated sEPCR, prothrombin F1+2, risk for coronary heart disease, and increased sEPCR shedding in vitro
-
Ireland H, Konstantoulas CJ, Cooper JA, Hawe E, Humphries SE, Mather H, Goodall AH, Hogwood J, Juhan-Vague I, Yudkin JS, di Minno G, Margaglione M, Hamsten A, Miller GJ, Bauer KA, Kim YT, Stearns-Kurosawa DJ, Kurosawa S. EPCR Ser219Gly: Elevated sEPCR, prothrombin F1+2, risk for coronary heart disease, and increased sEPCR shedding in vitro. Atherosclerosis 2005; 183: 283-92.
-
(2005)
Atherosclerosis
, vol.183
, pp. 283-292
-
-
Ireland, H.1
Konstantoulas, C.J.2
Cooper, J.A.3
Hawe, E.4
Humphries, S.E.5
Mather, H.6
Goodall, A.H.7
Hogwood, J.8
Juhan-Vague, I.9
Yudkin, J.S.10
di Minno, G.11
Margaglione, M.12
Hamsten, A.13
Miller, G.J.14
Bauer, K.A.15
Kim, Y.T.16
Stearns-Kurosawa, D.J.17
Kurosawa, S.18
-
12
-
-
0032055508
-
Predicting future years of healthy life for older adults
-
Diehr P, Patrick DL, Bild DE, Burke GL, Williamson JD. Predicting future years of healthy life for older adults. J Clin Epidemiol 1998; 51: 343-53.
-
(1998)
J Clin Epidemiol
, vol.51
, pp. 343-353
-
-
Diehr, P.1
Patrick, D.L.2
Bild, D.E.3
Burke, G.L.4
Williamson, J.D.5
-
13
-
-
0028908861
-
Laboratory methods and quality assurance in the Cardiovascular Health Study
-
Cushman M, Cornell ES, Howard PR, Bovill EG, Tracy RP. Laboratory methods and quality assurance in the Cardiovascular Health Study. Clin Chem 1995; 41: 264-70.
-
(1995)
Clin Chem
, vol.41
, pp. 264-270
-
-
Cushman, M.1
Cornell, E.S.2
Howard, P.R.3
Bovill, E.G.4
Tracy, R.P.5
-
14
-
-
0031870840
-
Correlates of antithrombin, protein C, protein S, and TFPI in a healthy elderly cohort
-
Sakkinen PA, Cushman M, Psaty BM, Kuller LH, Bajaj SP, Sabharwal AK, Boineau R, Macy E, Tracy RP. Correlates of antithrombin, protein C, protein S, and TFPI in a healthy elderly cohort. Thromb Haemost 1998; 80: 134-9.
-
(1998)
Thromb Haemost
, vol.80
, pp. 134-139
-
-
Sakkinen, P.A.1
Cushman, M.2
Psaty, B.M.3
Kuller, L.H.4
Bajaj, S.P.5
Sabharwal, A.K.6
Boineau, R.7
Macy, E.8
Tracy, R.P.9
-
15
-
-
0037079736
-
Plasma levels of endothelial protein C receptor respond to anticoagulant treatment
-
Stearns-Kurosawa DJ, Swindle K, D'Angelo A, Della Valle P, Fattorini A, Caron N, Grimaux M, Woodhams B, Kurosawa S. Plasma levels of endothelial protein C receptor respond to anticoagulant treatment. Blood 2002; 2: 526-30.
-
(2002)
Blood
, vol.2
, pp. 526-530
-
-
Stearns-Kurosawa, D.J.1
Swindle, K.2
D'Angelo, A.3
Della Valle, P.4
Fattorini, A.5
Caron, N.6
Grimaux, M.7
Woodhams, B.8
Kurosawa, S.9
-
16
-
-
0346373654
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
-
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 2004; 74: 106-20.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 106-120
-
-
Carlson, C.S.1
Eberle, M.A.2
Rieder, M.J.3
Yi, Q.4
Kruglyak, L.5
Nickerson, D.A.6
-
17
-
-
40949099467
-
Common genetic determinants of plasma fibrin D-dimer concentration in older European-and African-American adults
-
Lange LA, Reiner AP, Carty CA, Jenny NS, Cushman M, Lange EM. Common genetic determinants of plasma fibrin D-dimer concentration in older European-and African-American adults. J Thromb Haemost 2008; 6: 654-9.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 654-659
-
-
Lange, L.A.1
Reiner, A.P.2
Carty, C.A.3
Jenny, N.S.4
Cushman, M.5
Lange, E.M.6
-
18
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, Sham PC. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-75.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
Maller, J.7
Sklar, P.8
de Bakker, P.I.9
Daly, M.J.10
Sham, P.C.11
-
19
-
-
2342452445
-
Haplotype-based association analysis in cohort studies of unrelated individuals
-
Lin DY. Haplotype-based association analysis in cohort studies of unrelated individuals. Genet Epidemiol 2004; 26: 255-64.
-
(2004)
Genet Epidemiol
, vol.26
, pp. 255-264
-
-
Lin, D.Y.1
-
20
-
-
36749079336
-
So many correlated tests, so little time!Rapid adjustment of P-values for multiple correlated tests
-
Conneely KN, Boehnke M. So many correlated tests, so little time!Rapid adjustment of P -values for multiple correlated tests. Am J Hum Genet 2007; 81: 1158-68.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 1158-1168
-
-
Conneely, K.N.1
Boehnke, M.2
-
21
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey JD, Tibshirani R Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003; 100: 9440-5.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
22
-
-
55449112185
-
Genome-wide associations of gene expression variation in humans
-
Stranger BE, Forrest MS, Clark AG, Minichiello MJ, Deutsch S, Lyle R, Hunt S, Kahl B, Antonarakis SE, Tavare S, Deloukas P, Dermitzakis ET. Genome-wide associations of gene expression variation in humans. PLoS Genet 2005; 1: 695-704.
-
(2005)
PLoS Genet
, vol.1
, pp. 695-704
-
-
Stranger, B.E.1
Forrest, M.S.2
Clark, A.G.3
Minichiello, M.J.4
Deutsch, S.5
Lyle, R.6
Hunt, S.7
Kahl, B.8
Antonarakis, S.E.9
Tavare, S.10
Deloukas, P.11
Dermitzakis, E.T.12
-
23
-
-
0029059857
-
Polymorphic variation in the human protein C (PROC) gene promoter can influence transcriptional efficiency in vitro
-
Scopes D, Berg LP, Krawczak M, Kakkar VV, Cooper DN. Polymorphic variation in the human protein C (PROC) gene promoter can influence transcriptional efficiency in vitro. Blood Coagul Fibrinolysis 1995; 6: 317-21.
-
(1995)
Blood Coagul Fibrinolysis
, vol.6
, pp. 317-321
-
-
Scopes, D.1
Berg, L.P.2
Krawczak, M.3
Kakkar, V.V.4
Cooper, D.N.5
-
24
-
-
33745857955
-
The constitutive expression of anticoagulant protein S is regulated through multiple binding sites for Sp1 and Sp3 transcription factors in the protein S gene promoter
-
de Wolf CJ, Cupers RM, Bertina RM, Vos HL. The constitutive expression of anticoagulant protein S is regulated through multiple binding sites for Sp1 and Sp3 transcription factors in the protein S gene promoter. J Biol Chem 2006; 281: 17635-43.
-
(2006)
J Biol Chem
, vol.281
, pp. 17635-17643
-
-
de Wolf, C.J.1
Cupers, R.M.2
Bertina, R.M.3
Vos, H.L.4
-
25
-
-
33750057357
-
Regulation of the human protein S gene promoter by liver enriched transcription factors
-
Hall AJ, Peake IR, Winship PR Regulation of the human protein S gene promoter by liver enriched transcription factors. Br J Haematol 2006; 135: 538-46.
-
(2006)
Br J Haematol
, vol.135
, pp. 538-546
-
-
Hall, A.J.1
Peake, I.R.2
Winship, P.R.3
-
26
-
-
0028850076
-
The Ser. 460 to Pro substitution of the protein S alpha (PROS1) gene is a frequent mutation associated with free protein S (type.IIa) deficiency
-
Duchemin J, Gandrille S, Borgel D, Feurgard P, Alhenc-Gelas M, Matheron C, Dreyfus M, Dupuy E, Juhan-Vague I, Aiach M. The Ser. 460 to Pro substitution of the protein S alpha (PROS1) gene is a frequent mutation associated with free protein S (type.IIa) deficiency. Blood 1995; 86: 3436-43.
-
(1995)
Blood
, vol.86
, pp. 3436-3443
-
-
Duchemin, J.1
Gandrille, S.2
Borgel, D.3
Feurgard, P.4
Alhenc-Gelas, M.5
Matheron, C.6
Dreyfus, M.7
Dupuy, E.8
Juhan-Vague, I.9
Aiach, M.10
-
27
-
-
33644859098
-
The Ser219->Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype
-
Qu D, Wang Y, Song Y, Esmon NL, Esmon CT. The Ser219->Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype. J Thromb Haemost 2006; 4: 229-35.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 229-235
-
-
Qu, D.1
Wang, Y.2
Song, Y.3
Esmon, N.L.4
Esmon, C.T.5
-
29
-
-
33747187231
-
Role of a 5′-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene
-
Mollica LR, Crawley JT, Liu K, Rance JB, Cockerill PN, Follows GA, Landry JR, Wells DJ, Lane DA. Role of a 5′-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene. Blood 2006; 108: 1251-9.
-
(2006)
Blood
, vol.108
, pp. 1251-1259
-
-
Mollica, L.R.1
Crawley, J.T.2
Liu, K.3
Rance, J.B.4
Cockerill, P.N.5
Follows, G.A.6
Landry, J.R.7
Wells, D.J.8
Lane, D.A.9
-
30
-
-
2442433385
-
Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk
-
Medina P, Navarro S, Estellés A, VayáA, Woodhams B, Mira Y, Villa P, Migaud-Fressart M, Ferrando F, Aznar J, Bertina RM, España F. Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk. Thromb Haemost 2004; 91: 905-11.
-
(2004)
Thromb Haemost
, vol.91
, pp. 905-911
-
-
Medina, P.1
Navarro, S.2
Estellés, A.3
Vayá, A.4
Woodhams, B.5
Mira, Y.6
Villa, P.7
Migaud-Fressart, M.8
Ferrando, F.9
Aznar, J.10
Bertina, R.M.11
España, F.12
-
31
-
-
0037352279
-
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective
-
Cheng T, Liu D, Griffin JH, Fernández JA, Castellino F, Rosen ED, Fukudome K, Zlokovic BV. Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. Nat Med 2003; 9: 338-42.
-
(2003)
Nat Med
, vol.9
, pp. 338-342
-
-
Cheng, T.1
Liu, D.2
Griffin, J.H.3
Fernández, J.A.4
Castellino, F.5
Rosen, E.D.6
Fukudome, K.7
Zlokovic, B.V.8
-
32
-
-
0043240071
-
Expression and function of the endothelial protein C receptor in human neutrophils
-
Sturn DH, Kaneider NC, Feistritzer C, Djanani A, Fukudome K, Wiedermann CJ. Expression and function of the endothelial protein C receptor in human neutrophils. Blood 2003; 102: 1499-505.
-
(2003)
Blood
, vol.102
, pp. 1499-1505
-
-
Sturn, D.H.1
Kaneider, N.C.2
Feistritzer, C.3
Djanani, A.4
Fukudome, K.5
Wiedermann, C.J.6
-
33
-
-
30744439278
-
Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor
-
Feistritzer C, Mosheimer BA, Sturn DH, Riewald M, Patsch JR, Wiedermann CJ. Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor. J Immunol 2006; 176: 1019-25.
-
(2006)
J Immunol
, vol.176
, pp. 1019-1025
-
-
Feistritzer, C.1
Mosheimer, B.A.2
Sturn, D.H.3
Riewald, M.4
Patsch, J.R.5
Wiedermann, C.J.6
-
34
-
-
34948866150
-
Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
-
Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H. Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J Exp Med 2007; 204: 2439-48.
-
(2007)
J Exp Med
, vol.204
, pp. 2439-2448
-
-
Kerschen, E.J.1
Fernandez, J.A.2
Cooley, B.C.3
Yang, X.V.4
Sood, R.5
Mosnier, L.O.6
Castellino, F.J.7
Mackman, N.8
Griffin, J.H.9
Weiler, H.10
-
35
-
-
34250758543
-
Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia
-
Zheng X, Li W, Song Y, Hu Y, Ferrell GL, Esmon NL, Esmon CT. Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia. J Thromb Haemost 2007; 5: 1394-400.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1394-1400
-
-
Zheng, X.1
Li, W.2
Song, Y.3
Hu, Y.4
Ferrell, G.L.5
Esmon, N.L.6
Esmon, C.T.7
|