Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability

Vascular Cell

Volumn 4, Issue , 2012, Pages

  Krouwer, Vincent J D ^a   Hekking, Liesbeth H P ^a   Langelaar Makkinje, Miriam ^a   Regan Klapisz, Elsa ^a   Post, Jan Andries ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Atherosclerosis; cPLA2 ; Endothelial junctions; Endothelial permeability; Senescence

Indexed keywords

CLAUDIN 5; HORSERADISH PEROXIDASE; LUCIFER YELLOW; OCCLUDIN; TIGHT JUNCTION PROTEIN;

ARTICLE; CELL ADHESION; CELL AGING; CELL CULTURE; CELL DISRUPTION; CELL FUNCTION; CELL ISOLATION; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; COCULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TIGHT JUNCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ARMORACIA RUSTICANA;

EID: 84876362339     PISSN: None     EISSN: 2045824X     Source Type: Journal    
DOI: 10.1186/2045-824X-4-12     Document Type: Article

References (34)

1. Protein expression dynamics during replicative senescence of endothelial cells studied by 2-D difference in-gel electrophoresis. Eman MR, Regan-Klapisz E, Pinkse MW, Koop IM, Haverkamp J, Heck AJ, Verkleij AJ, Post JA, Electrophoresis 2006 27 1669 1682 10.1002/elps.200500746 16609940
2. Increased expression of extracellular proteins as a hallmark of human endothelial cell in vitro senescence. Hampel B, Fortschegger K, Ressler S, Chang MW, Unterluggauer H, Breitwieser A, Sommergruber W, Fitzky B, Lepperdinger G, Jansen-Durr P, Voglauer R, Grillari J, Exp Gerontol 2006 41 474 481 10.1016/j.exger.2006.03.001 16626901 (Pubitemid 43765898)
3. Cellular senescence: when bad things happen to good cells. Campisi J, d'Adda di Fagagna F, Nat Rev Mol Cell Biol 2007 8 729 740 17667954 (Pubitemid 47312822)
4. Cellular senescence in cancer and aging. Collado M, Blasco MA, Serrano M, Cell 2007 130 223 233 10.1016/j.cell.2007.07.003 17662938 (Pubitemid 47081143)
5. Identification of cultivation-independent markers of human endothelial cell senescence in vitro. Unterluggauer H, Hutter E, Voglauer R, Grillari J, Voth M, Bereiter-Hahn J, Jansen-Durr P, Jendrach M, Biogerontology 2007 8 383 397 10.1007/s10522-007-9082-x 17377850 (Pubitemid 47054796)
6. The senescence-associated secretory phenotype: the dark side of tumor suppression. Coppe JP, Desprez PY, Krtolica A, Campisi J, Annu. Rev. Pathol. 2010 5 99 118 10.1146/annurev-pathol-121808-102144 20078217
7. Identification of CD44 as a senescence-induced cell adhesion gene responsible for the enhanced monocyte recruitment to senescent endothelial cells. Mun GI, Boo YC, Am J Physiol Heart Circ Physiol 2010 298 2102 H2111 10.1152/ajpheart.00835.2009 20382854
8. Vascular endothelial senescence: from mechanisms to pathophysiology. Erusalimsky JD, J Appl Physiol 2009 106 326 332 19036896
9. Evaluation of endothelial cell culture as a model system of vascular ageing. Boisen L, Drasbek KR, Pedersen AS, Kristensen P, Exp Gerontol 2010 45 779 787 10.1016/j.exger.2010.06.003 20600781
10. Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. Vasile E, Tomita Y, Brown LF, Kocher O, Dvorak HF, FASEB J 2001 15 458 466 10.1096/fj.00-0051com 11156961 (Pubitemid 32141437)
11. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I, Circulation 2002 105 1541 1544 10.1161/01.CIR.0000013836.85741.17 11927518 (Pubitemid 34297628)
12. Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Bazzoni G, Dejana E, Physiol Rev 2004 84 869 901 10.1152/physrev.00035.2003 15269339 (Pubitemid 38823769)
13. Endothelial hyperpermeability in vascular leakage. van Hinsbergh VW, van Nieuw Amerongen GP, Vascul Pharmacol 2002 39 4-5 171 172 12747957 (Pubitemid 37490744)
14. Identification of replicative senescence-associated genes in human umbilical vein endothelial cells by an annealing control primer system. Kim TW, Kim HJ, Lee C, Kim HY, Baek SH, Kim JH, Kwon KS, Kim JR, Exp Gerontol 2008 43 286 295 10.1016/j.exger.2007.12.010 18258400
15. Hemodynamic forces in endothelial dysfu8nction and vascular ageing. Collins C, Tzima E, Exp Gerontol 2011 46 2-3 185 188 20888896
16. Senescence stimulates U937-endothelial cell interactions. Maier JA, Statuto M, Ragnotti G, Exp. Cell Res. 1993 208 270 274 10.1006/excr.1993.1246 8359220 (Pubitemid 23274513)
17. Mathematical modeling of vascular endothelial layer maintenance: the role of endothelial cell division, progenitor cell homing, and telomere shortening. Op den Buijs J, Musters M, Verrips T, Post JA, Braam B, van Riel N, Am J Physiol Heart Circ Physiol 2004 287 2651 H2658 10.1152/ajpheart.00332.2004 15284068 (Pubitemid 39557136)
18. Inflammation in atherosclerosis. Libby P, Nature 2002 420 868 874 10.1038/nature01323 12490960 (Pubitemid 36019640)
19. Atherosclerosis. Lusis AJ, Nature 2000 407 233 241 10.1038/35025203 11001066
20. Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries. Fenton M, Barker S, Kurz DJ, Erusalimsky JD, Arterioscler Thromb Vasc Biol 2001 21 220 226 10.1161/01.ATV.21.2.220 11156856 (Pubitemid 32125369)
21. Telomere shortening in human coronary artery diseases. Ogami M, Ikura Y, Ohsawa M, Matsuo T, Kayo S, Yoshimi N, Hai E, Shirai N, Ehara S, Komatsu R, Naruko T, Ueda M, Arterioscler Thromb Vasc Biol 2004 24 546 550 10.1161/01.ATV.0000117200.46938.e7 14726417 (Pubitemid 38326151)
22. Inhibition of telomerase activity alters tight junction protein expression and induces transendothelial migration of HIV-1-infected cells. Huang W, Rha GB, Chen L, Seelbach MJ, Zhang B, Andras IE, Bruemmer D, Hennig B, Toborek M, Am J Physiol Heart Circ Physiol 2010 298 1136 H1145 10.1152/ajpheart.01126.2009 20139322
23. RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction. Venkatesh D, Fredette N, Rostama B, Tang Y, Vary CP, Liaw L, Urs S, Arterioscler Thromb Vasc Biol 2011 31 876 882 10.1161/ATVBAHA.110.221945 21273559
24. Senescence of cultured porcine coronary arterial endothelial cells is associated with accelerated oxidative stress and activation of NFkB. Lee MY, Wang Y, Vanhoutte PM, J Vasc Res 2010 47 287 298 10.1159/000265563 20016203
25. Golgi-associated cPLA2alpha regulates endothelial cell-cell junction integrity by controlling the trafficking of transmembrane junction proteins. Regan-Klapisz E, Krouwer V, Langelaar-Makkinje M, Nallan L, Gelb M, Gerritsen H, Verkleij AJ, Post JA, Mol. Biol. Cell 2009 20 4225 4234 10.1091/mbc.E08-02-0210 19675210
26. Tannic acid-mediated osmium impregnation after freeze-substitution: a strategy to enhance membrane contrast for electron tomography. Jiménez N, Vocking K, van Donselaar EG, Humbel BM, Post JA, Verkleij AJ, J Struct Biol 2009 166 1 103 106 10.1016/j.jsb.2008.12.009 19162195
27. A novel approach for intracellular 3D immuno-labeling for electron-tomography. Jiménez N, Post JA, Traffic 2012 10.1111/j.1600-0854.2012.01363.x
28. A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination. Klapisz E, Sorokina I, Lemeer S, Pijnenburg M, Verkleij AJ, van Bergen en Henegouwen PM, J Biol Chem 2002 277 30746 30753 10.1074/jbc.M203004200 12072436 (Pubitemid 34970771)
29. Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. Taddei A, Giampietro C, Conti A, Orsenigo F, Breviario F, Pirazzoli V, Potente M, Daly C, Dimmeler S, Dejana E, Nat. Cell Biol. 2008 10 923 934 10.1038/ncb1752 18604199
30. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Campisi J, Cell 2005 120 513 522 10.1016/j.cell.2005.02.003 15734683 (Pubitemid 40269765)
31. The role of apoptosis in LDL transport through cultured endothelial cell monolayers. Cancel LM, Tarbell JM, Atherosclerosis 2010 208 335 341 10.1016/j.atherosclerosis.2009.07.051 19709659
32. Vascular endothelial responses to altered shear stress: pathologic implications for atherosclerosis. Chiu JJ, Usami S, Chien S, Ann. Med. 2009 41 19 28 10.1080/07853890802186921 18608132
33. Shear stress, SIRT1, and vascular homeostasis. Chen Z, Peng IC, Cui X, Li YS, Chien S, Shyy JY, Proc Natl Acad Sci U S A 2010 107 10268 10273 10.1073/pnas.1003833107 20479254
34. Effects of extensively oxidized low-density lipoprotein on mitochondrial function and reactive oxygen species in porcine aortic endothelial cells. Roy Chowdhury SK, Sangle GV, Xie X, Stelmack GL, Halayko AJ, Shen GX, Am J Physiol Endocrinol Metab 2010 298 89 E98 10.1152/ajpendo.00433.2009 19843872