Adiponectin as a routine clinical biomarker

Best Practice and Research: Clinical Endocrinology and Metabolism

Volumn 28, Issue 1, 2014, Pages 119-130

  Kishida, Ken ^a   Funahashi, Tohru ^a   Shimomura, Iichiro ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

adiponectin; hypoadiponectinemia; obesity related diseases; visceral fat

Indexed keywords

ADIPONECTIN; INSULIN;

ATHEROSCLEROSIS; CHRONIC KIDNEY DISEASE; CONFERENCE PAPER; CROHN DISEASE; DYSLIPIDEMIA; GASTRITIS; GASTROESOPHAGEAL REFLUX; HUMAN; HYPERTENSION; HYPERURICEMIA; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LIFESTYLE; LUNG DISEASE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OSTEOPOROSIS; PANCREATITIS; SLEEP DISORDERED BREATHING;

ADIPONECTIN; HYPOADIPONECTINEMIA; OBESITY-RELATED DISEASES; VISCERAL FAT;

ADIPONECTIN; BIOLOGICAL MARKERS; DIABETES MELLITUS, TYPE 2; DYSLIPIDEMIAS; FEMALE; HUMANS; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIFE STYLE; MALE; METABOLISM, INBORN ERRORS; OBESITY; PROTEIN MULTIMERIZATION; SLEEP APNEA SYNDROMES;

EID: 85047686970     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2013.08.006     Document Type: Conference Paper

References (100)

1. Y. Arita, S. Kihara, and N. Ouchi et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity Biochemical and Biophysical Research Communications 257 1999 79 83
2. M. Ryo, T. Nakamura, and S. Kihara et al. Adiponectin as a biomarker of the metabolic syndrome Circulation Journal 68 2004 975 981
3. Y. Okauchi, K. Kishida, and T. Funahashi et al. Changes in serum adiponectin concentrations correlate with changes in BMI, waist circumference, and estimated visceral fat area in middle-aged general population Diabetes Care 32 2009 e122
4. K. Kishida, K.K. Kim, and T. Funahashi et al. Relationships between circulating adiponectin levels and fat distribution in obese subjects Journal of Atherosclerosis and Thrombosis 18 2011 592 595
5. T.W. Ng, G.F. Watts, and P.H. Barrett et al. Effect of weight loss on LDL and HDL kinetics in the metabolic syndrome: associations with changes in plasma retinol-binding protein-4 and adiponectin levels Diabetes Care 30 2007 2945 2950
6. K. Hotta, T. Funahashi, and Y. Arita et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients Arteriosclerosis, Thrombosis, and Vascular Biology 20 2000 1595 1599
7. K. Kishida, T. Funahashi, and Y. Matsuzawa et al. Visceral adiposity as a target for the management of the metabolic syndrome Annals of Medicine 44 2012 233 241
8. S.A. Porter, J.M. Massaro, and U. Hoffmann et al. Abdominal subcutaneous adipose tissue: a protective fat depot? Diabetes Care 32 2009 1068 1075
9. A. Hiuge-Shimizu, K. Kishida, and T. Funahashi et al. Absolute value of visceral fat area measured on computed tomography scans and obesity-related cardiovascular risk factors in large-scale Japanese general population (the VACATION-J study) Annals of Medicine 44 2012 82 92
10. J.P. Després, and I. Lemieux Abdominal obesity and metabolic syndrome Nature 444 2006 881-8817
11. J.V. Silha, M. Krsek, and J.V. Skrha et al. Plasma resistin, adiponectin and leptin levels in lean and obese subjects: correlations with insulin resistance European Journal of Endocrinology 149 2003 331 335
12. H.L. Lu, H.W. Wang, and Y. Wen et al. Roles of adipocyte derived hormone adiponectin and resistin in insulin resistance of type 2 diabetes World Journal of Gastroenterology 12 2006 1747 1751
13. L. Qi, A. Doria, and J.E. Manson et al. Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes Diabetes 55 2006 1512 1516
14. K. Kishida, T. Funahashi, and I. Shimomura Molecular mechanisms of diabetes and atherosclerosis: role of adiponectin Endocrine, Metabolic & Immune Disorders - Drug Targets 12 2012 118 131
15. K. Hotta, T. Funahashi, and N.L. Bodkin et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys Diabetes 50 2001 1126 1133
16. R.S. Lindsay, T. Funahashi, and R.L. Hanson et al. Adiponectin and development of type 2 diabetes in the Pima Indian population Lancet 360 2002 57 58
17. F. Mallamaci, C. Zoccali, and F. Cuzzola et al. Adiponectin in essential hypertension Journal of Nephrology 15 2002 507 511
18. M. Adamczak, A. Wiecek, and T. Funahashi et al. Decreased plasma adiponectin concentration in patients with essential hypertension American Journal of Hypertension 16 2003 72 75
19. Y. Iwashima, T. Katsuya, and K. Ishikawa et al. Hypoadiponectinemia is an independent risk factor for hypertension Hypertension 43 2004 1318 1323
20. H.S. Lee, M. Lee, and H. Joung Adiponectin represents an independent risk factor for hypertension in middle aged Korean women Asia Pacific Journal of Clinical Nutrition. 16 2007 10 15
21. K. Ohashi, N. Ouchi, and Y. Matsuzawa Adiponectin and hypertension American Journal of Hypertension 24 2011 263 269
22. F. Matsuura, H. Oku, and M. Koseki et al. Adiponectin accelerates reverse cholesterol transport by increasing high density lipoprotein assembly in the liver Biochemical and Biophysical Research Communications 358 2007 1091 1095
23. H. Oku, F. Matsuura, and M. Koseki et al. Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver FEBS Letters 581 2007 5029 5033
24. V. Mohan, R. Deepa, and R. Pradeepa et al. Association of low adiponectin levels with the metabolic syndrome-the Chennai Urban Rural Epidemiology Study (CURES-4) Metabolism: Clinical and Experimental 54 2005 476 481
25. G.Q. Shaibi, M.L. Cruz, and M.J. Weigensberg et al. Adiponectin independently predicts metabolic syndrome in overweight Latino youth The Journal of Clinical Endocrinology and Metabolism 92 2007 1809 1813
26. A. Coutinho Tde, S.T. Turner, and P.A. Peyser et al. Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis American Journal of Hypertension 20 2007 83 89
27. A.G. Ioachimescu, D.M. Brennan, and B.M. Hoar et al. Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study Arthritis and Rheumatism 58 2008 623 630
28. J. Fang, and M.H. Alderman Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey JAMA 283 2000 2404 2410
29. S. Tamba, H. Nishizawa, and T. Funahashi et al. Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men Internal Medicine 47 2008 1175 1180
30. N. Ouchi, S. Kihara, and Y. Arita et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin Circulation 100 1999 2473 2476
31. M. Kumada, S. Kihara, S. Sumitsuji Osaka CAD Study Group Coronary artery disease. Association of hypoadiponectinemia with coronary artery disease in men Arteriosclerosis, Thrombosis, and Vascular Biology 23 2003 85 89
32. M. von Eynatten, J.G. Schneider, and P.M. Humpert et al. Serum adiponectin levels are an independent predictor of the extent of coronary artery disease in men Journal of the American College of Cardiology 47 2006 2124 2126
33. J.V. Patel, A. Abraheem, and O. Dotsenko et al. Circulating serum adiponectin levels in patients with coronary artery disease: relationship to atherosclerotic burden and cardiac function Journal of Internal Medicine 264 2008 593 598
34. T. Pischon, C.J. Girman, and G.S. Hotamisligil et al. Plasma adiponectin levels and risk of myocardial infarction in men JAMA 291 2004 1730 1737
35. C. Zoccali, F. Mallamaci, and G. Tripepi et al. Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease Journal of the American Society of Nephrology 13 2002 134 141
36. S.P. Efstathiou, D.I. Tsioulos, and A.G. Tsiakou et al. Plasma adiponectin levels and five-year survival after first-ever ischemic stroke Stroke 36 2005 1915 1919
37. J. Golledge, A. Leicht, and R.G. Crowther et al. Association of obesity and metabolic syndrome with the severity and outcome of intermittent claudication Journal of Vascular Surgery 45 2007 40 46
38. Y. Iwashima, T. Horio, and Y. Suzuki et al. Adiponectin and inflammatory markers in peripheral arterial occlusive disease Atherosclerosis 188 2006 384 390
39. T. Tamura, Y. Furukawa, and R. Taniguchi et al. Serum adiponectin level as an independent predictor of mortality in patients with congestive heart failure Circulation Journal 71 2007 623 630
40. T. Nakamura, H. Funayama, and N. Kubo et al. Association of hyperadiponectinemia with severity of ventricular dysfunction in congestive heart failure Circulation Journal 70 2006 1557 1562
41. C. Kistorp, J. Faber, and S. Galatius et al. Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure Circulation 112 2005 1756 1762
42. M.B. McEntegart, B. Awede, and M.C. Petrie et al. Increase in serum adiponectin concentration in patients with heart failure and cachexia: relationship with leptin, other cytokines, and B-type natriuretic peptide European Heart Journal 28 2007 829 835
43. A.M. Van Berendoncks, A. Garnier, and P. Beckers et al. Functional adiponectin resistance at the level of the skeletal muscle in mild to moderate chronic heart failure Circulation Heart Failure. 3 2010 185 194
44. O. Tsukamoto, M. Fujita, and M. Kato et al. Natriuretic peptides enhance the production of adiponectin in human adipocytes and in patients with chronic heart failure Journal of the American College of Cardiology 53 2009 2070 2077
45. B. Kollerits, D. Fliser, and I.M. Heid et al. MMKD study group gender-specific association of adiponectin as a predictor of progression of chronic kidney disease: the mild to moderate kidney disease study Kidney International 71 2007 1279 1286
46. A. Jorsal, L. Tarnow, and J. Frystyk et al. Serum adiponectin predicts all-cause mortality and end stage renal disease in patients with type I diabetes and diabetic nephropathy Kidney International. 74 2008 649 654
47. M.M. Lo, and M. Mitsnefes Adiponectin, cardiovascular disease, chronic kidney disease: emerging data on complex interactions Pediatric Nephrology 27 2012 521 527
48. K. Nakanishi, Y. Takeda, and S. Tetsumoto et al. Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy American Journal of Respiratory and Critical Care Medicine 183 2011 1164 1175
49. K. Tomoda, M. Yoshikawa, and T. Itoh et al. Elevated circulating plasma adiponectin in underweight patients with COPD Chest 132 2007 135 140
50. N. Ali Assad, and A. Sood Leptin, adiponectin and pulmonary diseases Biochimie 94 2012 2180 2189
51. A. Sood, E. Dominic, and C. Qualls et al. Serum adiponectin is associated with adverse outcomes of asthma in men but not in women Frontiers in Pharmacology 2 2011 55
52. A.S. Shamsuzzaman, B.J. Gersh, and V.K. Somers Obstructive sleep apnea: implications for cardiac and vascular disease JAMA 290 2003 1906 1914
53. Y. Nakagawa, K. Kishida, and S. Kihara et al. Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome American Journal of Physiology Endocrinology and Metabolism: Clinical and Experimental 294 2008 E778 E784
54. Y. Nakagawa, K. Kishida, and S. Kihara et al. Nocturnal falls of adiponectin levels in sleep apnea with abdominal obesity and impact of hypoxia-induced dysregulated adiponectin production in obese murine mesenteric adipose tissue Journal of Atherosclerosis and Thrombosis 18 2011 240 247
55. Y. Nakagawa, K. Kishida, and T. Mazaki et al. Impact of sleep-disordered breathing, visceral fat accumulation and adiponectin levels in patients with night-time onset of acute coronary syndrome The American Journal of Cardiology 108 2011 1266 1271
56. Y. Nakagawa, K. Kishida, and T. Funahashi et al. Coexistence of visceral fat accumulation and sleep-disordered breathing correlates with coronary artery disease Journal of Atherosclerosis and Thrombosis 19 2012 728 735
57. B.W. Smith, and L.A. Adams Non-alcoholic fatty liver disease Critical Reviews in Clinical Laboratory Sciences 48 2011 97 113
58. Y. Kamada, H. Matsumoto, and S. Tamura et al. Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model Journal of Hepatology 47 2007 556 564
59. Y. Kamada, T. Takehara, and N. Hayashi Adipocytokines and liver disease Journal of Gastroenterology 43 2008 811 822
60. J.M. Hui, A. Hodge, and G.C. Farrell et al. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 40 2004 46 54
61. N.K. Gatselis, G. Ntaios, and K. Makaritsis et al. Adiponectin: a key playmaker adipocytokine in non-alcoholic fatty liver disease Clinical and Experimental Medicine 2013
62. G. Targher, L. Bertolini, and S. Rodella et al. Associations between plasma adiponectin concentrations and liver histology in patients with nonalcoholic fatty liver disease Clinical Endocrinology (Oxford) 64 2006 679 683
63. S.A. Polyzos, K.A. Toulis, and D.G. Goulis et al. Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis Metabolism: Clinical and Experimental 60 2011 313 326
64. S.K. Dutta, M. Arora, and A. Kireet et al. Upper gastrointestinal symptoms and associated disorders in morbidly obese patients: a prospective study Digestive Diseases and Sciences 54 2009 1243 1246
65. S. Yamamoto, K. Watabe, and T. Takehara Is obesity a new risk factor for gastritis? Digestion 85 2012 108 110
66. E. Iwasaki, H. Suzuki, and Y. Sugino et al. Decreased levels of adiponectin in obese patients with gastroesophageal reflux evaluated by videoesophagography: possible relationship between gastroesophageal reflux and metabolic syndrome Journal of Gastroenterology and Hepatology 23 2008 S216 S221
67. S. Ayazi, J.A. Hagen, and L.S. Chan et al. Obesity and gastroesophageal reflux: quantifying the association between body mass index, esophageal acid exposure, and lower esophageal sphincter status in a large series of patients with reflux symptoms Journal of Gastrointestinal Surgery 13 2009 1440 1447
68. H.L. Lee, C.S. Eun, and O.Y. Lee et al. Association between erosive esophagitis and visceral fat accumulation quantified by abdominal CT scan Journal of Clinical Gastroenterology 43 2009 240 243
69. S. Yamamoto, K. Watabe, and S. Tsutsui et al. Lower serum level of adiponectin is associated with increased risk of endoscopic erosive gastritis Digestive Diseases and Sciences 56 2011 2354 2360
70. M. Kato, K. Watabe, and T. Hamasaki et al. Association of low serum adiponectin levels with erosive esophagitis in men: an analysis of 2405 subjects undergoing physical check-ups Journal of Gastroenterology 46 2011 1361 1367
71. A. Hirata, K. Kishida, and H. Nakatsuji et al. High prevalence of gastroesophageal reflux symptoms in type 2 diabetics with hypoadiponectinemia and metabolic syndrome Nutrition & Metabolism (London) 9 2012 4
72. P.M. Ridker High-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary prevention The American Journal of Cardiology 92 2003 17K 22K
73. N. Ouchi, S. Kihara, and T. Funahashi et al. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue Circulation 107 2003 671 674
74. K. Yamamoto, T. Kiyohara, and Y. Murayama et al. Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease Gut 54 2005 789 796
75. V.S. Rodrigues, M. Milanski, and J.J. Fagundes et al. Serum levels and mesenteric fat tissue expression of adiponectin and leptin in patients with Crohn's disease Clinical and Experimental Immunology 170 2012 358 364
76. H.G. Kim, and J. Han Obesity and pancreatic diseases The Korean Journal of Gastroenterology 59 2012 35 39
77. H. Araki, T. Nishihara, and M. Matsuda et al. Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet Gut 57 2008 1431 1440
78. T. Yamada, H. Araki, and K. Watabe et al. Adiponectin deficiency enhanced the severity of cerulein-induced chronic pancreatitis in mice Journal of Gastroenterology 45 2010 742 749
79. A. Sharma, V. Muddana, and J. Lamb et al. Low serum adiponectin levels are associated with systemic organ failure in acute pancreatitis Pancreas 38 2009 907 912
80. E. Tukiainen, M.L. Kylanpaa, and P. Ebeling et al. Leptin and adiponectin levels in acute pancreatitis Pancreas 32 2006 211 214
81. K. Adrych, M. Smoczynski, and E. Stelmanska et al. Serum adiponectin and leptin concentrations in patients with chronic pancreatitis of alcoholic and nonalcoholic origin Pancreas 36 2008 120 124
82. E. Biver, C. Salliot, and C. Combescure et al. Influence of adipokines and ghrelin on bone mineral density and fracture risk: a systematic review and meta-analysis The Journal of Clinical Endocrinology and Metabolism 96 2011 2703 2713
83. I. Kelesidis, T. Kelesidis, and C.S. Mantzoros Adiponectin and cancer: a systematic review British Journal of Cancer 94 2006 1221 1225
84. L. Dal Maso, L.S. Augustin, and A. Karalis et al. Circulating adiponectin and endometrial cancer risk The Journal of Clinical Endocrinology and Metabolism 89 2004 1160 1163
85. C. Mantzoros, E. Petridou, and N. Dessypris et al. Adiponectin and breast cancer risk The Journal of Clinical Endocrinology and Metabolism 89 2004 1102 1107
86. F. Avcu, A.U. Ural, and M.I. Yilmaz et al. Association of plasma adiponectin concentrations with chronic lymphocytic leukemia and myeloproliferative diseases International Journal of Hematology 83 2006 254 258
87. E.K. Wei, E. Giovannucci, and C.S. Fuchs et al. Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study Journal of the National Cancer Institute 97 2005 1688 1694
88. M. Ishikawa, J. Kitayama, and S. Kazama et al. Plasma adiponectin and gastric cancer Clinical Cancer Research 11 2005 466 472
89. S. Goktas, M.I. Yilmaz, and K. Caglar et al. Prostate cancer and adiponectin Urology 65 2005 1168 1172
90. H. Nishizawa, I. Shimomura, and K. Kishida et al. Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein Diabetes 51 2002 2734 2741
91. F. Lanfranco, M. Zitzmann, and M. Simoni et al. Serum adiponectin levels in hypogonadal males: influence of testosterone replacement therapy Clinical Endocrinology (Oxford) 60 2004 500 507
92. K. Kotani, A. Hazama, and A. Hagimoto et al. Adiponectin and smoking status: a systematic review Journal of Atherosclerosis and Thrombosis 19 2012 787 794
93. K. Kotani, N. Sakane, and K. Saiga et al. Serum adiponectin levels and lifestyle factors in Japanese men Heart Vessels 22 2007 291 296
94. U.B. Pajvani, X. Du, and T.P. Combs et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity The Journal of Biological Chemistry 278 2003 9073 9085
95. Y. Arita, S. Kihara, and N. Ouchi et al. Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell Circulation 105 2002 2893 2898
96. Y. Takemura, N. Ouchi, and R. Shibata et al. Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies The Journal of Clinical Investigation 117 2007 375 386
97. H. Masaie, K. Oritani, and T. Yokota et al. Adiponectin binds to chemokines via the globular head and modulates interactions between chemokines and heparan sulfates Experimental Hematology 35 2007 947 956
98. N. Komura, S. Kihara, and M. Sonoda et al. Increment and impairment of adiponectin in renal failure Cardiovascular Research 86 2010 471 477
99. H. Nakatsuji, H. Kobayashi, and K. Kishida et al. Binding of adiponectin and C1q in human serum, and clinical significance of the measurement of C1q-adiponectin/total adiponectin ratio Metabolism: Clinical and Experimental 62 2013 109 120
100. A. Hirata, K. Kishida, and H. Nakatsuji et al. High serum C1q-adiponectin/total adiponectin ratio correlates with coronary artery disease in Japanese type 2 diabetics Metabolism: Clinical and Experimental 2012 [in press]