메뉴 건너뛰기




Volumn 1, Issue 6, 2014, Pages 163-178

Cell-autonomous mechanisms of chronological aging in the yeast Saccharomyces cerevisiae

Author keywords

Carbohydrate metabolism; Cell autonomous mechanisms of longevity regulation; Lipid metabolism; Mitochondria; Proteostasis; Systems biology of cellular aging; Yeast chronological aging

Indexed keywords


EID: 84907875412     PISSN: None     EISSN: 23112638     Source Type: Journal    
DOI: 10.15698/mic2014.06.152     Document Type: Review
Times cited : (31)

References (137)
  • 1
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • Fontana L, Partridge L, Longo VD (2010). Extending healthy life span-from yeast to humans. Science 328(5976): 321-6.
    • (2010) Science , vol.328 , Issue.5976 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 2
    • 77950214581 scopus 로고    scopus 로고
    • Lessons on longevity from budding yeast
    • Kaeberlein M (2010). Lessons on longevity from budding yeast. Nature 464(7288): 513-9.
    • (2010) Nature , vol.464 , Issue.7288 , pp. 513-519
    • Kaeberlein, M.1
  • 3
    • 84863524526 scopus 로고    scopus 로고
    • Replicative and chronological aging in Saccharomyces cerevisiae
    • Longo VD, Shadel GS, Kaeberlein M, Kennedy B (2012). Replicative and chronological aging in Saccharomyces cerevisiae. Cell Metab 16(1): 18-31.
    • (2012) Cell Metab , vol.16 , Issue.1 , pp. 18-31
    • Longo, V.D.1    Shadel, G.S.2    Kaeberlein, M.3    Kennedy, B.4
  • 4
    • 84876815772 scopus 로고    scopus 로고
    • Yeast colonies: A model for studies of aging, environmental adaptation, and longevity
    • Váchová L, Cáp M, Palková Z (2012). Yeast colonies: a model for studies of aging, environmental adaptation, and longevity. Oxid Med Cell Longev 2012: 601836.
    • (2012) Oxid Med Cell Longev , vol.2012
    • Váchová, L.1    Cáp, M.2    Palková, Z.3
  • 5
    • 84896707743 scopus 로고    scopus 로고
    • Budding yeast as a model organism to study the effects of age
    • Denoth Lippuner A, Julou T, Barral Y (2014). Budding yeast as a model organism to study the effects of age. FEMS Microbiol Rev 38 (2): 300-325.
    • (2014) FEMS Microbiol Rev , vol.38 , Issue.2 , pp. 300-325
    • Denoth Lippuner, A.1    Julou, T.2    Barral, Y.3
  • 6
    • 84893813516 scopus 로고    scopus 로고
    • Protein quality control in time and space-links to cellular aging
    • Nyström T, Liu B (2014). Protein quality control in time and space-links to cellular aging. FEMS Yeast Res 14(1): 40-8.
    • (2014) FEMS Yeast Res , vol.14 , Issue.1 , pp. 40-48
    • Nyström, T.1    Liu, B.2
  • 8
    • 81255197643 scopus 로고    scopus 로고
    • Yeast: An experimental organism for 21st Century biology
    • Botstein D, Fink GR (2011). Yeast: an experimental organism for 21st Century biology. Genetics 189(3): 695-704.
    • (2011) Genetics , vol.189 , Issue.3 , pp. 695-704
    • Botstein, D.1    Fink, G.R.2
  • 9
    • 84859463277 scopus 로고    scopus 로고
    • Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform
    • Lee SS, Avalos Vizcarra I, Huberts DH, Lee LP, Heinemann M (2012). Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform. Proc Natl Acad Sci USA 109(13): 4916-20.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.13 , pp. 4916-4920
    • Lee, S.S.1    Avalos Vizcarra, I.2    Huberts, D.H.3    Lee, L.P.4    Heinemann, M.5
  • 11
    • 84864019027 scopus 로고    scopus 로고
    • Molecular phenotyping of aging in single yeast cells using a novel microfluidic device
    • Xie Z, Zhang Y, Zou K, Brandman O, Luo C, Ouyang Q, Li H (2012). Molecular phenotyping of aging in single yeast cells using a novel microfluidic device. Aging Cell 11(4): 599-606.
    • (2012) Aging Cell , vol.11 , Issue.4 , pp. 599-606
    • Xie, Z.1    Zhang, Y.2    Zou, K.3    Brandman, O.4    Luo, C.5    Ouyang, Q.6    Li, H.7
  • 12
    • 84869051816 scopus 로고    scopus 로고
    • Single cell analysis of yeast replicative aging using a new generation of microfluidic device
    • Zhang Y, Luo C, Zou K, Xie Z, Brandman O, Ouyang Q, Li H (2012). Single cell analysis of yeast replicative aging using a new generation of microfluidic device. PLoS One 7(11): e48275.
    • (2012) Plos One , vol.7 , Issue.11
    • Zhang, Y.1    Luo, C.2    Zou, K.3    Xie, Z.4    Brandman, O.5    Ouyang, Q.6    Li, H.7
  • 15
    • 77955747346 scopus 로고    scopus 로고
    • With TOR, less is more: A key role for the conserved nutrient-sensing TOR pathway in aging
    • Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, Kockel L (2010). With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 11(6): 453-65.
    • (2010) Cell Metab , vol.11 , Issue.6 , pp. 453-465
    • Kapahi, P.1    Chen, D.2    Rogers, A.N.3    Katewa, S.D.4    Li, P.W.5    Thomas, E.L.6    Kockel, L.7
  • 16
    • 79952455618 scopus 로고    scopus 로고
    • TOR signaling never gets old: Aging, longevity and TORC1 activity
    • Evans DS, Kapahi P, Hsueh WC, Kockel L (2011). TOR signaling never gets old: aging, longevity and TORC1 activity. Ageing Res Rev 10(2): 225-37.
    • (2011) Ageing Res Rev , vol.10 , Issue.2 , pp. 225-237
    • Evans, D.S.1    Kapahi, P.2    Hsueh, W.C.3    Kockel, L.4
  • 17
    • 84857704648 scopus 로고    scopus 로고
    • Polyamines in aging and disease
    • Minois N, Carmona-Gutierrez D, Madeo F (2011). Polyamines in aging and disease. Aging 3(8): 716-32.
    • (2011) Aging , vol.3 , Issue.8 , pp. 716-732
    • Minois, N.1    Carmona-Gutierrez, D.2    Madeo, F.3
  • 18
    • 84930201480 scopus 로고    scopus 로고
    • The retrograde response and other pathways of interorganelle communication in yeast replicative aging
    • Jazwinski SM (2012). The retrograde response and other pathways of interorganelle communication in yeast replicative aging. Subcell Biochem 57: 79-100.
    • (2012) Subcell Biochem , vol.57 , pp. 79-100
    • Jazwinski, S.M.1
  • 19
    • 84871741160 scopus 로고    scopus 로고
    • The retrograde response: When mitochondrial quality control is not enough
    • Jazwinski SM (2013). The retrograde response: when mitochondrial quality control is not enough. Biochim Biophys Acta 1833(2): 400-9.
    • (2013) Biochim Biophys Acta , vol.1833 , Issue.2 , pp. 400-409
    • Jazwinski, S.M.1
  • 20
    • 84890800995 scopus 로고    scopus 로고
    • A network of interorganellar communications underlies cellular aging
    • Leonov A, Titorenko VI (2013). A network of interorganellar communications underlies cellular aging. IUBMB Life 65(8): 665-74.
    • (2013) IUBMB Life , vol.65 , Issue.8 , pp. 665-674
    • Leonov, A.1    Titorenko, V.I.2
  • 21
    • 84896739647 scopus 로고    scopus 로고
    • Small molecule SIRT1 activators for the treatment of aging and age-related diseases
    • Hubbard BP, Sinclair DA (2014). Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends Pharmacol Sci 35(3): 146-54.
    • (2014) Trends Pharmacol Sci , vol.35 , Issue.3 , pp. 146-154
    • Hubbard, B.P.1    Sinclair, D.A.2
  • 22
    • 84891848670 scopus 로고    scopus 로고
    • Small-molecule allosteric activators of sirtuins
    • Sinclair DA, Guarente L (2014). Small-molecule allosteric activators of sirtuins. Annu Rev Pharmacol Toxicol 54: 363-80.
    • (2014) Annu Rev Pharmacol Toxicol , vol.54 , pp. 363-380
    • Sinclair, D.A.1    Guarente, L.2
  • 24
    • 80055114735 scopus 로고    scopus 로고
    • Measuring replicative life span in the budding yeast
    • Steffen KK, Kennedy BK, Kaeberlein M (2009). Measuring replicative life span in the budding yeast. J Vis Exp 28: 1209.
    • (2009) J Vis Exp , Issue.28 , pp. 1209
    • Steffen, K.K.1    Kennedy, B.K.2    Kaeberlein, M.3
  • 25
    • 84878862158 scopus 로고    scopus 로고
    • Assessing chronological aging in Saccharomyces cerevisiae
    • Hu J, Wei M, Mirisola MG, Longo VD (2013). Assessing chronological aging in Saccharomyces cerevisiae. Methods Mol Biol 965: 463-72.
    • (2013) Methods Mol Biol , vol.965 , pp. 463-472
    • Hu, J.1    Wei, M.2    Mirisola, M.G.3    Longo, V.D.4
  • 26
    • 84934439598 scopus 로고    scopus 로고
    • Studying the replicative life span of yeast cells
    • Sinclair DA (2013). Studying the replicative life span of yeast cells. Methods Mol Biol 1048: 49-63.
    • (2013) Methods Mol Biol , vol.1048 , pp. 49-63
    • Sinclair, D.A.1
  • 28
    • 80055111017 scopus 로고    scopus 로고
    • Quantifying yeast chronological life span by outgrowth of aged cells
    • Murakami C, Kaeberlein M (2009). Quantifying yeast chronological life span by outgrowth of aged cells. J Vis Exp 27: 1156.
    • (2009) J Vis Exp , Issue.27 , pp. 1156
    • Murakami, C.1    Kaeberlein, M.2
  • 29
    • 80054848214 scopus 로고    scopus 로고
    • A high throughput screening assay for determination of chronological lifespan of yeast
    • Wu Z, Song L, Liu SQ, Huang D (2011). A high throughput screening assay for determination of chronological lifespan of yeast. Exp Gerontol 46(11): 915-22.
    • (2011) Exp Gerontol , vol.46 , Issue.11 , pp. 915-922
    • Wu, Z.1    Song, L.2    Liu, S.Q.3    Huang, D.4
  • 30
    • 34548727395 scopus 로고    scopus 로고
    • The chronological life span of Saccharomyces cerevisiae
    • Fabrizio P, Longo VD (2007). The chronological life span of Saccharomyces cerevisiae. Methods Mol Biol 371: 89-95.
    • (2007) Methods Mol Biol , vol.371 , pp. 89-95
    • Fabrizio, P.1    Longo, V.D.2
  • 31
    • 84893792592 scopus 로고    scopus 로고
    • Maximising the yeast chronological lifespan
    • Piper PW (2012). Maximising the yeast chronological lifespan. Subcell Biochem 57: 145-59.
    • (2012) Subcell Biochem , vol.57 , pp. 145-159
    • Piper, P.W.1
  • 32
    • 33746228121 scopus 로고    scopus 로고
    • Sirtuins in aging and age-related disease
    • Longo VD, Kennedy BK (2006). Sirtuins in aging and age-related disease. Cell 126(2): 257-68.
    • (2006) Cell , vol.126 , Issue.2 , pp. 257-268
    • Longo, V.D.1    Kennedy, B.K.2
  • 33
    • 84866360129 scopus 로고    scopus 로고
    • Chronological aging in Saccharomyces cerevisiae
    • Longo VD, Fabrizio P (2012). Chronological aging in Saccharomyces cerevisiae. Subcell Biochem 57: 101-21.
    • (2012) Subcell Biochem , vol.57 , pp. 101-121
    • Longo, V.D.1    Fabrizio, P.2
  • 34
    • 0141677687 scopus 로고    scopus 로고
    • Longevity regulation in Saccharomyces cerevisiae: Linking metabolism, genome stability, and heterochromatin
    • Bitterman KJ, Medvedik O, Sinclair DA (2003). Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin. Microbiol Mol Biol Rev 67(3): 376-99.
    • (2003) Microbiol Mol Biol Rev , vol.67 , Issue.3 , pp. 376-399
    • Bitterman, K.J.1    Medvedik, O.2    Sinclair, D.A.3
  • 36
    • 78449252869 scopus 로고    scopus 로고
    • General factors important for the formation of structured biofilm-like yeast colonies
    • St'ovíček V, Váchová L, Kuthan M, Palková Z (2010). General factors important for the formation of structured biofilm-like yeast colonies. Fungal Genet Biol 47(12): 1012-22.
    • (2010) Fungal Genet Biol , vol.47 , Issue.12 , pp. 1012-1022
    • St'ovíček, V.1    Váchová, L.2    Kuthan, M.3    Palková, Z.4
  • 37
    • 80053361325 scopus 로고    scopus 로고
    • Aging and longevity of yeast colony populations: Metabolic adaptation and differentiation
    • Váchová L, Palková Z (2011). Aging and longevity of yeast colony populations: metabolic adaptation and differentiation. Biochem Soc Trans 39(5): 1471-5.
    • (2011) Biochem Soc Trans , vol.39 , Issue.5 , pp. 1471-1475
    • Váchová, L.1    Palková, Z.2
  • 38
    • 84861455657 scopus 로고    scopus 로고
    • Cell differentiation within a yeast colony: Metabolic and regulatory parallels with a tumor-affected organism
    • Cáp M, Stěpánek L, Harant K, Váchová L, Palková Z (2012a). Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. Mol Cell 46(4): 436-48.
    • (2012) Mol Cell , vol.46 , Issue.4 , pp. 436-448
    • Cáp, M.1    Stěpánek, L.2    Harant, K.3    Váchová, L.4    Palková, Z.5
  • 39
    • 84864929433 scopus 로고    scopus 로고
    • Reactive oxygen species in the signaling and adaptation of multicellular microbial communities
    • Cáp M, Váchová L, Palková Z (2012b). Reactive oxygen species in the signaling and adaptation of multicellular microbial communities. Oxid Med Cell Longev 2012:976753.
    • (2012) Oxid Med Cell Longev , vol.2012
    • Cáp, M.1    Váchová, L.2    Palková, Z.3
  • 40
    • 84884272336 scopus 로고    scopus 로고
    • Hypothesis: Is yeast a clock model to study the onset of humans aging phenotypes?
    • Mazzoni C, Mangiapelo E, Palermo V, Falcone C (2012). Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes? Front Oncol 2: 203.
    • (2012) Front Oncol , vol.2 , pp. 203
    • Mazzoni, C.1    Mangiapelo, E.2    Palermo, V.3    Falcone, C.4
  • 41
    • 84881539908 scopus 로고    scopus 로고
    • Rapidly developing yeast microcolonies differentiate in a similar way to aging giant colonies
    • Váchová L, Hatáková L, Cáp M, Pokorná M, Palková Z (2013). Rapidly developing yeast microcolonies differentiate in a similar way to aging giant colonies. Oxid Med Cell Longev 2013: 102485.
    • (2013) Oxid Med Cell Longev , vol.2013
    • Váchová, L.1    Hatáková, L.2    Cáp, M.3    Pokorná, M.4    Palková, Z.5
  • 42
    • 84893795284 scopus 로고    scopus 로고
    • Aging and differentiation in yeast populations: Elders with different properties and functions
    • Palková Z, Wilkinson D, Váchová L (2014). Aging and differentiation in yeast populations: Elders with different properties and functions. FEMS Yeast Res 14(1): 96-108.
    • (2014) FEMS Yeast Res , vol.14 , Issue.1 , pp. 96-108
    • Palková, Z.1    Wilkinson, D.2    Váchová, L.3
  • 43
    • 84894273748 scopus 로고    scopus 로고
    • Global changes in gene expression associated with phenotypic switching of wild yeast
    • Sťovíček V, Váchová L, Begany M, Wilkinson D, Palková Z (2014). Global changes in gene expression associated with phenotypic switching of wild yeast. BMC Genomics 15(1): 136.
    • (2014) BMC Genomics , vol.15 , Issue.1 , pp. 136
    • Sťovíček, V.1    Váchová, L.2    Begany, M.3    Wilkinson, D.4    Palková, Z.5
  • 44
    • 43049095216 scopus 로고    scopus 로고
    • Xenohormesis: Sensing the chemical cues of other species
    • Howitz KT, Sinclair DA (2008). Xenohormesis: sensing the chemical cues of other species. Cell 133(3): 387-91.
    • (2008) Cell , vol.133 , Issue.3 , pp. 387-391
    • Howitz, K.T.1    Sinclair, D.A.2
  • 45
    • 79952113686 scopus 로고    scopus 로고
    • Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level
    • Goldberg AA, Kyryakov P, Bourque SD, Titorenko VI (2010b). Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level. Aging 2(8): 461-70.
    • (2010) Aging , vol.2 , Issue.8 , pp. 461-470
    • Goldberg, A.A.1    Kyryakov, P.2    Bourque, S.D.3    Titorenko, V.I.4
  • 46
    • 84859081964 scopus 로고    scopus 로고
    • Interspecies chemical signals released into the environment may create xenohormetic, hormetic and cytostatic selective forces that drive the ecosystemic evolution of longevity regulation mechanisms
    • Burstein MT, Beach A, Richard VR, Koupaki O, Gomez-Perez A, Goldberg AA, Kyryakov P, Bourque SD, Glebov A, Titorenko VI (2012a). Interspecies chemical signals released into the environment may create xenohormetic, hormetic and cytostatic selective forces that drive the ecosystemic evolution of longevity regulation mechanisms. Dose Response 10(1): 75-82.
    • (2012) Dose Response , vol.10 , Issue.1 , pp. 75-82
    • Burstein, M.T.1    Beach, A.2    Richard, V.R.3    Koupaki, O.4    Gomez-Perez, A.5    Goldberg, A.A.6    Kyryakov, P.7    Bourque, S.D.8    Glebov, A.9    Titorenko, V.I.10
  • 48
    • 4344590155 scopus 로고    scopus 로고
    • Small molecules that regulate lifespan: Evidence for xenohormesis
    • Lamming DW, Wood JG, Sinclair DA (2004). Small molecules that regulate lifespan: evidence for xenohormesis. Mol Microbiol 53(4):1003-9.
    • (2004) Mol Microbiol , vol.53 , Issue.4 , pp. 1003-1009
    • Lamming, D.W.1    Wood, J.G.2    Sinclair, D.A.3
  • 49
    • 34548270589 scopus 로고    scopus 로고
    • Rethinking the mitochondrial theory of aging: The role of mitochondrial gene expression in lifespan determination
    • Bonawitz ND, Shadel GS (2007). Rethinking the mitochondrial theory of aging: the role of mitochondrial gene expression in lifespan determination. Cell Cycle 6(13): 1574-8.
    • (2007) Cell Cycle , vol.6 , Issue.13 , pp. 1574-1578
    • Bonawitz, N.D.1    Shadel, G.S.2
  • 50
    • 33947574775 scopus 로고    scopus 로고
    • Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression
    • Bonawitz ND, Chatenay-Lapointe M, Pan Y, Shadel GS (2007). Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. Cell Metab 5(4): 265-77.
    • (2007) Cell Metab , vol.5 , Issue.4 , pp. 265-277
    • Bonawitz, N.D.1    Chatenay-Lapointe, M.2    Pan, Y.3    Shadel, G.S.4
  • 51
    • 68049109688 scopus 로고    scopus 로고
    • Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density
    • Pan Y, Shadel GS (2009). Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. Aging 1(1): 131-45.
    • (2009) Aging , vol.1 , Issue.1 , pp. 131-145
    • Pan, Y.1    Shadel, G.S.2
  • 52
    • 67149130284 scopus 로고    scopus 로고
    • Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension
    • Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM, Longo VD (2009). Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS Genet 5(5): e1000467.
    • (2009) Plos Genet , vol.5 , Issue.5
    • Wei, M.1    Fabrizio, P.2    Madia, F.3    Hu, J.4    Ge, H.5    Li, L.M.6    Longo, V.D.7
  • 54
    • 80052870831 scopus 로고    scopus 로고
    • In search of housekeeping pathways that regulate longevity
    • Beach A, Titorenko VI (2011). In search of housekeeping pathways that regulate longevity. Cell Cycle 10(18): 3042-4.
    • (2011) Cell Cycle , vol.10 , Issue.18 , pp. 3042-3044
    • Beach, A.1    Titorenko, V.I.2
  • 55
    • 80054856662 scopus 로고    scopus 로고
    • Mitochondria, reactive oxygen species, and chronological aging: A message from yeast
    • Pan Y (2011). Mitochondria, reactive oxygen species, and chronological aging: a message from yeast. Exp Gerontol 46(11): 847-52.
    • (2011) Exp Gerontol , vol.46 , Issue.11 , pp. 847-852
    • Pan, Y.1
  • 56
    • 79958068191 scopus 로고    scopus 로고
    • Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling
    • Pan Y, Schroeder EA, Ocampo A, Barrientos A, Shadel GS (2011). Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling. Cell Metab 13(6): 668-78.
    • (2011) Cell Metab , vol.13 , Issue.6 , pp. 668-678
    • Pan, Y.1    Schroeder, E.A.2    Ocampo, A.3    Barrientos, A.4    Shadel, G.S.5
  • 57
    • 79751472085 scopus 로고    scopus 로고
    • Peroxisome metabolism and cellular aging
    • Titorenko VI, Terlecky SR (2011). Peroxisome metabolism and cellular aging. Traffic 12(3): 252-9.
    • (2011) Traffic , vol.12 , Issue.3 , pp. 252-259
    • Titorenko, V.I.1    Terlecky, S.R.2
  • 60
    • 84870169302 scopus 로고    scopus 로고
    • Driving the cell cycle through metabolism
    • Cai L, Tu BP (2012). Driving the cell cycle through metabolism. Annu Rev Cell Dev Biol 28: 59-87.
    • (2012) Annu Rev Cell Dev Biol , vol.28 , pp. 59-87
    • Cai, L.1    Tu, B.P.2
  • 61
    • 84866437541 scopus 로고    scopus 로고
    • Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration
    • Kyryakov P, Beach A, Richard VR, Burstein MT, Leonov A, Levy S, Titorenko VI (2012). Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration. Front Physiol 3: 256.
    • (2012) Front Physiol , vol.3 , pp. 256
    • Kyryakov, P.1    Beach, A.2    Richard, V.R.3    Burstein, M.T.4    Leonov, A.5    Levy, S.6    Titorenko, V.I.7
  • 62
    • 84863527085 scopus 로고    scopus 로고
    • Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction
    • Ocampo A, Liu J, Schroeder EA, Shadel GS, Barrientos A (2012). Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction. Cell Metab 16(1): 55-67.
    • (2012) Cell Metab , vol.16 , Issue.1 , pp. 55-67
    • Ocampo, A.1    Liu, J.2    Schroeder, E.A.3    Shadel, G.S.4    Barrientos, A.5
  • 63
    • 84879040219 scopus 로고    scopus 로고
    • A new answer to old questions
    • Barral Y (2013). A new answer to old questions. eLife 2: e00515.
    • (2013) Elife , vol.2
    • Barral, Y.1
  • 65
    • 84905793528 scopus 로고    scopus 로고
    • Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity
    • Beach A, Titorenko VI (2013). Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity. Subcell Biochem 69: 153-67.
    • (2013) Subcell Biochem , vol.69 , pp. 153-167
    • Beach, A.1    Titorenko, V.I.2
  • 68
    • 84878776252 scopus 로고    scopus 로고
    • A radical signal activates the epigenetic regulation of longevity
    • Mirisola MG, Longo VD (2013). A radical signal activates the epigenetic regulation of longevity. Cell Metab 17(6): 812-3.
    • (2013) Cell Metab , vol.17 , Issue.6 , pp. 812-813
    • Mirisola, M.G.1    Longo, V.D.2
  • 69
    • 84884274955 scopus 로고    scopus 로고
    • Ethanol and acetate acting as carbon/energy sources negatively affect yeast chronological aging
    • Orlandi I, Ronzulli R, Casatta N, Vai M (2013). Ethanol and acetate acting as carbon/energy sources negatively affect yeast chronological aging. Oxid Med Cell Longev 2013: 802870.
    • (2013) Oxid Med Cell Longev , vol.2013
    • Orlandi, I.1    Ronzulli, R.2    Casatta, N.3    Vai, M.4
  • 71
    • 84878797603 scopus 로고    scopus 로고
    • Epigenetic silencing mediates mitochondria stress-induced longevity
    • Schroeder EA, Raimundo N, Shadel GS (2013). Epigenetic silencing mediates mitochondria stress-induced longevity. Cell Metab 17(6): 954-64.
    • (2013) Cell Metab , vol.17 , Issue.6 , pp. 954-964
    • Schroeder, E.A.1    Raimundo, N.2    Shadel, G.S.3
  • 72
    • 84873623073 scopus 로고    scopus 로고
    • Calorie restriction hysteretically primes aging Saccharomyces cerevisiae toward more effective oxidative metabolism
    • Tahara EB, Cunha FM, Basso TO, Della Bianca BE, Gombert AK, Kowaltowski AJ (2013). Calorie restriction hysteretically primes aging Saccharomyces cerevisiae toward more effective oxidative metabolism. PLoS One 8(2): e56388.
    • (2013) Plos One , vol.8 , Issue.2
    • Tahara, E.B.1    Cunha, F.M.2    Basso, T.O.3    della Bianca, B.E.4    Gombert, A.K.5    Kowaltowski, A.J.6
  • 75
    • 84863903065 scopus 로고    scopus 로고
    • Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: Progress and prognosis
    • Lindquist SL, Kelly JW (2011). Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis. Cold Spring Harb Perspect Biol 3(12): a004507.
    • (2011) Cold Spring Harb Perspect Biol , vol.3 , Issue.12
    • Lindquist, S.L.1    Kelly, J.W.2
  • 80
    • 79955505833 scopus 로고    scopus 로고
    • Peroxisome assembly: Matrix and membrane protein biogenesis
    • Ma C, Agrawal G, Subramani S (2011). Peroxisome assembly: matrix and membrane protein biogenesis. J Cell Biol 193(1): 7-16.
    • (2011) J Cell Biol , vol.193 , Issue.1 , pp. 7-16
    • Ma, C.1    Agrawal, G.2    Subramani, S.3
  • 81
    • 84865279926 scopus 로고    scopus 로고
    • Recent advances in peroxisomal matrix protein import
    • Liu X, Ma C, Subramani S (2012). Recent advances in peroxisomal matrix protein import. Curr Opin Cell Biol 24(4): 484-9.
    • (2012) Curr Opin Cell Biol , vol.24 , Issue.4 , pp. 484-489
    • Liu, X.1    Ma, C.2    Subramani, S.3
  • 82
    • 84884553260 scopus 로고    scopus 로고
    • Import of proteins into the peroxisomal matrix
    • Hasan S, Platta HW, Erdmann R (2013). Import of proteins into the peroxisomal matrix. Front Physiol 4: 261.
    • (2013) Front Physiol , vol.4 , pp. 261
    • Hasan, S.1    Platta, H.W.2    Erdmann, R.3
  • 83
    • 1442334370 scopus 로고    scopus 로고
    • The peroxisome: Orchestrating important developmental decisions from inside the cell
    • Titorenko VI, Rachubinski RA (2004). The peroxisome: orchestrating important developmental decisions from inside the cell. J Cell Biol 164(5): 641-5.
    • (2004) J Cell Biol , vol.164 , Issue.5 , pp. 641-645
    • Titorenko, V.I.1    Rachubinski, R.A.2
  • 85
    • 79955506970 scopus 로고    scopus 로고
    • Intraperoxisomal redox balance in mammalian cells: Oxidative stress and interorganellar cross-talk
    • Ivashchenko O, Van Veldhoven PP, Brees C, Ho YS, Terlecky SR, Fransen M (2011). Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk. Mol Biol Cell 22(9): 1440-51.
    • (2011) Mol Biol Cell , vol.22 , Issue.9 , pp. 1440-1451
    • Ivashchenko, O.1    van Veldhoven, P.P.2    Brees, C.3    Ho, Y.S.4    Terlecky, S.R.5    Fransen, M.6
  • 87
    • 84866320015 scopus 로고    scopus 로고
    • Effects of peroxisomal catalase inhibition on mitochondrial function
    • Walton PA, Pizzitelli M (2012). Effects of peroxisomal catalase inhibition on mitochondrial function. Front Physiol 3: 108.
    • (2012) Front Physiol , vol.3 , pp. 108
    • Walton, P.A.1    Pizzitelli, M.2
  • 89
    • 84895098727 scopus 로고    scopus 로고
    • Peroxisomal metabolism and oxidative stress
    • Nordgren M, Fransen M (2014). Peroxisomal metabolism and oxidative stress. Biochimie 98:56-62.
    • (2014) Biochimie , vol.98 , pp. 56-62
    • Nordgren, M.1    Fransen, M.2
  • 91
    • 84874966979 scopus 로고    scopus 로고
    • Peroxisomal catalase deficiency modulates yeast lifespan depending on growth conditions
    • Kawałek A, Lefevre SD, Veenhuis M, van der Klei IJ (2013). Peroxisomal catalase deficiency modulates yeast lifespan depending on growth conditions. Aging 5(1): 67-83.
    • (2013) Aging , vol.5 , Issue.1 , pp. 67-83
    • Kawałek, A.1    Lefevre, S.D.2    Veenhuis, M.3    van der Klei, I.J.4
  • 92
    • 84883764638 scopus 로고    scopus 로고
    • The significance of peroxisome function in chronological aging of Saccharomyces cerevisiae
    • Lefevre SD, van Roermund CW, Wanders RJ, Veenhuis M, van der Klei IJ (2013). The significance of peroxisome function in chronological aging of Saccharomyces cerevisiae. Aging Cell 12(5): 784-93.
    • (2013) Aging Cell , vol.12 , Issue.5 , pp. 784-793
    • Lefevre, S.D.1    van Roermund, C.W.2    Wanders, R.J.3    Veenhuis, M.4    van der Klei, I.J.5
  • 93
    • 84903522116 scopus 로고    scopus 로고
    • Molecular basis of the 'anti-aging' effect of spermidine and other natural polyamines-a mini-review
    • Epub ahead of print
    • Minois N (2014). Molecular basis of the 'anti-aging' effect of spermidine and other natural polyamines-a mini-review. Gerontology [Epub ahead of print].
    • (2014) Gerontology
    • Minois, N.1
  • 97
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
    • D'Autréaux B, Toledano MB (2007). ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 8(10): 813-24.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.10 , pp. 813-824
    • D'autréaux, B.1    Toledano, M.B.2
  • 98
    • 34548148201 scopus 로고    scopus 로고
    • Hydrogen peroxide: A metabolic by-product or a common mediator of ageing signals?
    • Giorgio M, Trinei M, Migliaccio E, Pelicci PG (2007). Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat Rev Mol Cell Biol 8(9): 722-8.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.9 , pp. 722-728
    • Giorgio, M.1    Trinei, M.2    Migliaccio, E.3    Pelicci, P.G.4
  • 99
    • 34147210988 scopus 로고    scopus 로고
    • Hydrogen peroxide sensing and signaling
    • Veal EA, Day AM, Morgan BA (2007). Hydrogen peroxide sensing and signaling. Mol Cell 26(1): 1-14.
    • (2007) Mol Cell , vol.26 , Issue.1 , pp. 1-14
    • Veal, E.A.1    Day, A.M.2    Morgan, B.A.3
  • 100
    • 57649116078 scopus 로고    scopus 로고
    • The gregarious lipid droplet
    • Goodman JM (2008). The gregarious lipid droplet. J Biol Chem 283(42): 28005-9.
    • (2008) J Biol Chem , vol.283 , Issue.42 , pp. 28005-28009
    • Goodman, J.M.1
  • 102
    • 84871820511 scopus 로고    scopus 로고
    • Lipid droplets and peroxisomes: Key players in cellular lipid homeostasis or a matter of fat-store 'em up or burn 'em down
    • Kohlwein SD, Veenhuis M, van der Klei IJ (2013). Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat-store 'em up or burn 'em down. Genetics 193(1): 1-50.
    • (2013) Genetics , vol.193 , Issue.1 , pp. 1-50
    • Kohlwein, S.D.1    Veenhuis, M.2    van der Klei, I.J.3
  • 103
    • 84892575595 scopus 로고    scopus 로고
    • Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death
    • Sheibani S, Richard VR, Beach A, Leonov A, Feldman R, Mattie S, Khelghatybana L, Piano A, Greenwood M, Vali H, Titorenko VI (2014). Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death. Cell Cycle 13(1): 138-47.
    • (2014) Cell Cycle , vol.13 , Issue.1 , pp. 138-147
    • Sheibani, S.1    Richard, V.R.2    Beach, A.3    Leonov, A.4    Feldman, R.5    Mattie, S.6    Khelghatybana, L.7    Piano, A.8    Greenwood, M.9    Vali, H.10    Titorenko, V.I.11
  • 104
    • 33845329876 scopus 로고    scopus 로고
    • The significance of peroxisomes in methanol metabolism in methylotrophic yeast
    • van der Klei IJ, Yurimoto H, Sakai Y, Veenhuis M (2006). The significance of peroxisomes in methanol metabolism in methylotrophic yeast. Biochim Biophys Acta 1763(12): 1453-62.
    • (2006) Biochim Biophys Acta , vol.1763 , Issue.12 , pp. 1453-1462
    • van der Klei, I.J.1    Yurimoto, H.2    Sakai, Y.3    Veenhuis, M.4
  • 105
    • 33746880713 scopus 로고    scopus 로고
    • Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast
    • Piper PW, Harris NL, MacLean M (2006). Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast. Mech Ageing Dev 127(9): 733-40.
    • (2006) Mech Ageing Dev , vol.127 , Issue.9 , pp. 733-740
    • Piper, P.W.1    Harris, N.L.2    Maclean, M.3
  • 106
    • 47049116691 scopus 로고    scopus 로고
    • Increased respiration in the sch9Δ mutant is required for increasing chronological life span but not replicative life span
    • Lavoie H, Whiteway M (2008). Increased respiration in the sch9Δ mutant is required for increasing chronological life span but not replicative life span. Eukaryot Cell 7(7): 1127-35.
    • (2008) Eukaryot Cell , vol.7 , Issue.7 , pp. 1127-1135
    • Lavoie, H.1    Whiteway, M.2
  • 107
    • 84893666025 scopus 로고    scopus 로고
    • A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology
    • Burstein MT, Titorenko VI (2014). A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology. Redox Biol 2:305-7.
    • (2014) Redox Biol , vol.2 , pp. 305-307
    • Burstein, M.T.1    Titorenko, V.I.2
  • 108
    • 84894362401 scopus 로고    scopus 로고
    • Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan
    • Schroeder EA, Shadel GS (2014). Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan. Mech Ageing Dev 135: 41-9.
    • (2014) Mech Ageing Dev , vol.135 , pp. 41-49
    • Schroeder, E.A.1    Shadel, G.S.2
  • 109
    • 84866076360 scopus 로고    scopus 로고
    • Nutritional control of growth and development in yeast
    • Broach JR (2012). Nutritional control of growth and development in yeast. Genetics 192(1): 73-105.
    • (2012) Genetics , vol.192 , Issue.1 , pp. 73-105
    • Broach, J.R.1
  • 110
    • 84856753762 scopus 로고    scopus 로고
    • The essence of yeast quiescence
    • De Virgilio C (2012). The essence of yeast quiescence. FEMS Microbiol Rev 36(2): 306-39.
    • (2012) FEMS Microbiol Rev , vol.36 , Issue.2 , pp. 306-339
    • de Virgilio, C.1
  • 114
    • 79955604127 scopus 로고    scopus 로고
    • A genomic analysis of chronological longevity factors in budding yeast
    • Burtner CR, Murakami CJ, Olsen B, Kennedy BK, Kaeberlein M (2011). A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle 10(9): 1385-96.
    • (2011) Cell Cycle , vol.10 , Issue.9 , pp. 1385-1396
    • Burtner, C.R.1    Murakami, C.J.2    Olsen, B.3    Kennedy, B.K.4    Kaeberlein, M.5
  • 117
  • 118
    • 84868704975 scopus 로고    scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor
    • Fraenkel DG (2011). Yeast intermediary metabolism. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
    • (2011) Yeast Intermediary Metabolism
    • Fraenkel, D.G.1
  • 119
    • 0037076314 scopus 로고    scopus 로고
    • The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine
    • Crespo JL, Powers T, Fowler B, Hall MN (2002). The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine. Proc Natl Acad Sci USA 99(10): 6784-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.10 , pp. 6784-6789
    • Crespo, J.L.1    Powers, T.2    Fowler, B.3    Hall, M.N.4
  • 120
    • 30944458446 scopus 로고    scopus 로고
    • Extension of chronological life span in yeast by decreased TOR pathway signaling
    • Powers RW 3rd, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S (2006). Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev 20(2): 174-84.
    • (2006) Genes Dev , vol.20 , Issue.2 , pp. 174-184
    • Powers, R.W.1    Kaeberlein, M.2    Caldwell, S.D.3    Kennedy, B.K.4    Fields, S.5
  • 123
    • 84894523716 scopus 로고    scopus 로고
    • Making new contacts: The mTOR network in metabolism and signalling crosstalk
    • Shimobayashi M, Hall MN (2014). Making new contacts: the mTOR network in metabolism and signalling crosstalk. Nat Rev Mol Cell Biol 15(3): 155-62.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , Issue.3 , pp. 155-162
    • Shimobayashi, M.1    Hall, M.N.2
  • 124
    • 84893743405 scopus 로고    scopus 로고
    • Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae
    • Swinnen E, Ghillebert R, Wilms T, Winderickx J (2014). Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae. FEMS Yeast Res 14(1): 17-32.
    • (2014) FEMS Yeast Res , vol.14 , Issue.1 , pp. 17-32
    • Swinnen, E.1    Ghillebert, R.2    Wilms, T.3    Winderickx, J.4
  • 125
    • 67349214589 scopus 로고    scopus 로고
    • Aging defined by a chronologic-replicative protein network in Saccharomyces cerevisiae: An interac-tome analysis
    • Barea F, Bonatto D (2009). Aging defined by a chronologic-replicative protein network in Saccharomyces cerevisiae: an interac-tome analysis. Mech Ageing Dev 130(7): 444-60.
    • (2009) Mech Ageing Dev , vol.130 , Issue.7 , pp. 444-460
    • Barea, F.1    Bonatto, D.2
  • 127
    • 84861205165 scopus 로고    scopus 로고
    • A network-based approach on elucidating the multi-faceted nature of chronological aging in S. Cerevisiae
    • Borklu Yucel E, Ulgen KO (2011). A network-based approach on elucidating the multi-faceted nature of chronological aging in S. cerevisiae. PLoS One 6(12): e29284.
    • (2011) Plos One , vol.6 , Issue.12
    • Borklu Yucel, E.1    Ulgen, K.O.2
  • 129
    • 67549142261 scopus 로고    scopus 로고
    • Life and death partners: Apoptosis, autophagy and the cross-talk between them
    • Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A (2009). Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 16(7): 966-75.
    • (2009) Cell Death Differ , vol.16 , Issue.7 , pp. 966-975
    • Eisenberg-Lerner, A.1    Bialik, S.2    Simon, H.U.3    Kimchi, A.4
  • 131
    • 77955916249 scopus 로고    scopus 로고
    • The road not taken: A systems level strategy for analyzing the cell death network
    • Zalckvar E, Bialik S, Kimchi A (2010). The road not taken: a systems level strategy for analyzing the cell death network. Autophagy 6(6): 813-5.
    • (2010) Autophagy , vol.6 , Issue.6 , pp. 813-815
    • Zalckvar, E.1    Bialik, S.2    Kimchi, A.3
  • 132
    • 77954661101 scopus 로고    scopus 로고
    • A systems level strategy for analyzing the cell death network: Implication in exploring the apoptosis/autophagy connection
    • Zalckvar E, Yosef N, Reef S, Ber Y, Rubinstein AD, Mor I, Sharan R, Ruppin E, Kimchi A (2010). A systems level strategy for analyzing the cell death network: implication in exploring the apoptosis/autophagy connection. Cell Death Differ 17(8): 1244-53.
    • (2010) Cell Death Differ , vol.17 , Issue.8 , pp. 1244-1253
    • Zalckvar, E.1    Yosef, N.2    Reef, S.3    Ber, Y.4    Rubinstein, A.D.5    Mor, I.6    Sharan, R.7    Ruppin, E.8    Kimchi, A.9
  • 134
    • 84873546725 scopus 로고    scopus 로고
    • Life in the balance-a mechanistic view of the crosstalk between autophagy and apoptosis
    • Rubinstein AD, Kimchi A (2012). Life in the balance-a mechanistic view of the crosstalk between autophagy and apoptosis. J Cell Sci 125(22): 5259-68.
    • (2012) J Cell Sci , vol.125 , Issue.22 , pp. 5259-5268
    • Rubinstein, A.D.1    Kimchi, A.2
  • 135
    • 84871250128 scopus 로고    scopus 로고
    • Sphingolipids: Regulators of crosstalk between apoptosis and autophagy
    • Young MM, Kester M, Wang HG (2013). Sphingolipids: regulators of crosstalk between apoptosis and autophagy. J Lipid Res 54(1): 5-19.
    • (2013) J Lipid Res , vol.54 , Issue.1 , pp. 5-19
    • Young, M.M.1    Kester, M.2    Wang, H.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.