-
1
-
-
33646885699
-
Energy metabolism and oxidative stress: Impact on the metabolic syndrome and the ageing process
-
Frisard, M. & Ravussin, E. Energy metabolism and oxidative stress: impact on the metabolic syndrome and the ageing process. Endocrine 29, 27-32 (2006).
-
(2006)
Endocrine
, vol.29
, pp. 27-32
-
-
Frisard, M.1
Ravussin, E.2
-
2
-
-
0032409515
-
Ageing: Phenomena and theories
-
Harman, D. Ageing: phenomena and theories. Ann. NY Acad. Sci. 854, 1-7 (1998).
-
(1998)
Ann. NY Acad. Sci
, vol.854
, pp. 1-7
-
-
Harman, D.1
-
3
-
-
13944278132
-
Mitochondria, oxidants, and ageing
-
Balaban, R. S., Nemoto, S., & Finkel, T. Mitochondria, oxidants, and ageing. Cell 120, 483-495 (2005).
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
4
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance, B., Sies, H. & Boveris, A. Hydroperoxide metabolism in mammalian organs. Physiol Rev. 59, 527-605 (1979).
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
5
-
-
27444442915
-
Enhanced catabolism of mitochondrial superoxide/ hydrogen peroxide and ageing in transgenic Drosophila
-
Bayne, A. C., Mockett, R. J., Orr, W. C. & Sohal, R. S. Enhanced catabolism of mitochondrial superoxide/ hydrogen peroxide and ageing in transgenic Drosophila. Biochem. J. 391, 277-284 (2005).
-
(2005)
Biochem. J
, vol.391
, pp. 277-284
-
-
Bayne, A.C.1
Mockett, R.J.2
Orr, W.C.3
Sohal, R.S.4
-
6
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
Valko, M. et al. Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 39, 44-84 (2007).
-
(2007)
Int. J. Biochem. Cell Biol
, vol.39
, pp. 44-84
-
-
Valko, M.1
-
7
-
-
33746802358
-
Redox signaling in cancer biology
-
Gius, D. & Spitz, D. R. Redox signaling in cancer biology. Antioxid. Redox Signal. 8, 1249-1252 (2006).
-
(2006)
Antioxid. Redox Signal
, vol.8
, pp. 1249-1252
-
-
Gius, D.1
Spitz, D.R.2
-
8
-
-
33646698671
-
Hydrogen peroxide: A signaling messenger
-
Stone, J. R. & Yang, S. Hydrogen peroxide: a signaling messenger. Antioxid. Redox Signal. 8, 243-270 (2006).
-
(2006)
Antioxid. Redox Signal
, vol.8
, pp. 243-270
-
-
Stone, J.R.1
Yang, S.2
-
9
-
-
0035815274
-
Structural basis of the redox switch in the OxyR transcription factor
-
Choi, H. et al. Structural basis of the redox switch in the OxyR transcription factor. Cell 105, 103-113 (2001).
-
(2001)
Cell
, vol.105
, pp. 103-113
-
-
Choi, H.1
-
10
-
-
2942538583
-
Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration
-
Vivancos, A. P., Castillo, E. A., Jones, N., Ayte, J. & Hidalgo, E. Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration. Mol. Microbiol. 52, 1427-1435 (2004).
-
(2004)
Mol. Microbiol
, vol.52
, pp. 1427-1435
-
-
Vivancos, A.P.1
Castillo, E.A.2
Jones, N.3
Ayte, J.4
Hidalgo, E.5
-
12
-
-
0034163437
-
HIV-2 protease is inactivated after oxidation at the dimer interface and activity can be partly restored with methionine sulphoxide reductase
-
Davis, D. A. et al. HIV-2 protease is inactivated after oxidation at the dimer interface and activity can be partly restored with methionine sulphoxide reductase. Biochem. J. 346, 305-311 (2000).
-
(2000)
Biochem. J
, vol.346
, pp. 305-311
-
-
Davis, D.A.1
-
13
-
-
0041816286
-
Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide
-
Atmane, N., Dairou, J., Paul, A., Dupret, J. M. & Rodrigues-Lima, F. Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide. J. Biol. Chem. 278, 35086-35092 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 35086-35092
-
-
Atmane, N.1
Dairou, J.2
Paul, A.3
Dupret, J.M.4
Rodrigues-Lima, F.5
-
15
-
-
33646932991
-
Effects of biological oxidants on the catalytic activity and structure of group VIA phospholipase A2
-
Song, H., Bao, S., Ramanadham, S. & Turk, J. Effects of biological oxidants on the catalytic activity and structure of group VIA phospholipase A2. Biochemistry 45, 6392-6406 (2006).
-
(2006)
Biochemistry
, vol.45
, pp. 6392-6406
-
-
Song, H.1
Bao, S.2
Ramanadham, S.3
Turk, J.4
-
16
-
-
31544432283
-
Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes
-
Bossis, G. & Melchior, F. Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes. Mol. Cell 21, 349-357 (2006).
-
(2006)
Mol. Cell
, vol.21
, pp. 349-357
-
-
Bossis, G.1
Melchior, F.2
-
17
-
-
0032546955
-
Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor
-
Lee, S. R., Kwon, K. S., Kim, S. R. & Rhee, S. G. Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273, 15366-15372 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 15366-15372
-
-
Lee, S.R.1
Kwon, K.S.2
Kim, S.R.3
Rhee, S.G.4
-
18
-
-
23944468310
-
redox regulation of PTEN by S-nitrosothiols
-
Yu, C. K., Li, S. & Whorton, A. R. redox regulation of PTEN by S-nitrosothiols. Mol. Pharmacol. 68, 847-854 (2005).
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 847-854
-
-
Yu, C.K.1
Li, S.2
Whorton, A.R.3
-
19
-
-
17644390613
-
2: Regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification
-
2: regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification. Antioxid. Redox Signal. 7, 619-626 (2005).
-
(2005)
Antioxid. Redox Signal
, vol.7
, pp. 619-626
-
-
Rhee, S.G.1
Yang, K.S.2
Kang, S.W.3
Woo, H.A.4
Chang, T.S.5
-
20
-
-
0346850874
-
Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence
-
Woo, H. A. et al. Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence. J. Biol. Chem. 278, 47361-47364 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 47361-47364
-
-
Woo, H.A.1
-
21
-
-
1542379828
-
Regulation of annexin A2 by reversible glutathionylation
-
Caplan, J. F., Filipenko, N. R., Fitzpatrick, S. L. & Waisman, D. M. Regulation of annexin A2 by reversible glutathionylation. J. Biol. Chem. 279, 7740-7750 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 7740-7750
-
-
Caplan, J.F.1
Filipenko, N.R.2
Fitzpatrick, S.L.3
Waisman, D.M.4
-
22
-
-
0037442768
-
Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress
-
Ahn, S. G. & Thiele, D. J. Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress. Genes Dev. 17, 516-528 (2003).
-
(2003)
Genes Dev
, vol.17
, pp. 516-528
-
-
Ahn, S.G.1
Thiele, D.J.2
-
23
-
-
0346365099
-
Redox-dependent modulation of aconitase activity in intact mitochondria
-
Bulteau, A. L., Ikeda-Saito, M. & Szweda, L. I. Redox-dependent modulation of aconitase activity in intact mitochondria. Biochemistry 42, 14846-14855 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 14846-14855
-
-
Bulteau, A.L.1
Ikeda-Saito, M.2
Szweda, L.I.3
-
24
-
-
0345146921
-
Reversible inactivation of α-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status
-
Nulton-Persoson, A. C., Starke, D. W., Mieval, J. J. & Szweda, L. I. Reversible inactivation of α-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry 42, 4235-4242 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 4235-4242
-
-
Nulton-Persoson, A.C.1
Starke, D.W.2
Mieval, J.J.3
Szweda, L.I.4
-
25
-
-
0037490142
-
Reversible glutathionylation of complex I increases mitochondrial superoxide formation
-
Taylor, E. R. et al. Reversible glutathionylation of complex I increases mitochondrial superoxide formation. J. Biol. Chem. 278, 19603-19610 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 19603-19610
-
-
Taylor, E.R.1
-
26
-
-
0034282101
-
Sensitive and nonenzymatic measurement of hydrogen peroxide in biological systems
-
Mueller, S. Sensitive and nonenzymatic measurement of hydrogen peroxide in biological systems. Free Radic. Biol. Med. 29, 410-415 (2000).
-
(2000)
Free Radic. Biol. Med
, vol.29
, pp. 410-415
-
-
Mueller, S.1
-
27
-
-
0035212036
-
Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli
-
Seaver, L. C. & Imlay, J. A. Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli. J. Bacteriol. 183, 7182-7189 (2001).
-
(2001)
J. Bacteriol
, vol.183
, pp. 7182-7189
-
-
Seaver, L.C.1
Imlay, J.A.2
-
28
-
-
0034973677
-
Dissecting the superoxide dismutase-ascorbate-glutathione- pathway in chloroplasts by metabolic modeling. Computer simulation as a step towards flux analysis
-
Polle, A. Dissecting the superoxide dismutase-ascorbate-glutathione- pathway in chloroplasts by metabolic modeling. Computer simulation as a step towards flux analysis. Plant Physiol. 126, 445-462 (2001).
-
(2001)
Plant Physiol
, vol.126
, pp. 445-462
-
-
Polle, A.1
-
29
-
-
0034733807
-
Redox-dependent signal transduction
-
Finkel, T. Redox-dependent signal transduction. FEBS Lett. 476, 52-54 (2000).
-
(2000)
FEBS Lett
, vol.476
, pp. 52-54
-
-
Finkel, T.1
-
30
-
-
33744916271
-
ROS up-regulation mediates Ras-induced changes of cell morphology and motility
-
Alexandrova, A. Y., Kopnin, P. B., Vasiliev, J. M. & Kopnin, B. P. ROS up-regulation mediates Ras-induced changes of cell morphology and motility. Exp. Cell Res. 312, 2066-2073 (2006).
-
(2006)
Exp. Cell Res
, vol.312
, pp. 2066-2073
-
-
Alexandrova, A.Y.1
Kopnin, P.B.2
Vasiliev, J.M.3
Kopnin, B.P.4
-
31
-
-
0036285034
-
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
-
Vafa, O. et al. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol. Cell 9, 1031-1044 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 1031-1044
-
-
Vafa, O.1
-
32
-
-
0037194596
-
Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts
-
Schimmel, M., Bauer. G. Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts. Oncogene 21, 5886-5896 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 5886-5896
-
-
Schimmel, M.1
Bauer, G.2
-
33
-
-
33751522909
-
The redox regulation of thiol dependent signaling pathways in cancer
-
Giles, G. I. The redox regulation of thiol dependent signaling pathways in cancer. Curr. Pharm. Des. 12, 4427-4443 (2006).
-
(2006)
Curr. Pharm. Des
, vol.12
, pp. 4427-4443
-
-
Giles, G.I.1
-
34
-
-
11444250615
-
Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors
-
North, S., Moenner, M. & Bikfalvi, A. Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett. 218, 1-14 (2005).
-
(2005)
Cancer Lett
, vol.218
, pp. 1-14
-
-
North, S.1
Moenner, M.2
Bikfalvi, A.3
-
35
-
-
4444233558
-
Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B
-
Meng, T. C., Buckley D.A, Galic, S., Tiganis, T. & Tonks, N. K. Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J. Biol. Chem. 279, 37716-37725 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 37716-37725
-
-
Meng, T.C.1
Buckley, D.A.2
Galic, S.3
Tiganis, T.4
Tonks, N.K.5
-
36
-
-
1342308079
-
2-mediated cell signaling
-
2-mediated cell signaling. FEBS Lett. 560, 7-13 (2004).
-
(2004)
FEBS Lett
, vol.560
, pp. 7-13
-
-
Cho, S.H.1
-
38
-
-
0037780966
-
Reactive oxygen species as essential mediators of cell adhesion: The oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion
-
Chiarugi, P. et al. Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion. J. Cell Biol. 161, 933-944 (2003).
-
(2003)
J. Cell Biol
, vol.161
, pp. 933-944
-
-
Chiarugi, P.1
-
39
-
-
0036184190
-
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
-
Meng, T. C., Fukada, T. & Tonks, N. K. Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol. Cell 9, 387-399 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 387-399
-
-
Meng, T.C.1
Fukada, T.2
Tonks, N.K.3
-
40
-
-
0041323072
-
Catalytic and chemical competence of regulation of CDC25 phosphatase by oxidation/reduction
-
Sohn, J. & Rudolph, J. Catalytic and chemical competence of regulation of CDC25 phosphatase by oxidation/reduction. Biochemistry 42, 10060-10070 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 10060-10070
-
-
Sohn, J.1
Rudolph, J.2
-
41
-
-
11144285380
-
Redox control of catalytic activities of membrane-associated protein tyrosine kinases
-
Nakashima, I. et al. Redox control of catalytic activities of membrane-associated protein tyrosine kinases. Arch. Biochem. Biophys. 434, 3-10 (2005).
-
(2005)
Arch. Biochem. Biophys
, vol.434
, pp. 3-10
-
-
Nakashima, I.1
-
42
-
-
33745193908
-
Redox signaling in hypertension
-
Paravicini, T. M. & Touyz, R. M. Redox signaling in hypertension. Cardiovasc. Res. 71, 247-258 (2006).
-
(2006)
Cardiovasc. Res
, vol.71
, pp. 247-258
-
-
Paravicini, T.M.1
Touyz, R.M.2
-
43
-
-
33750703909
-
Oxygen free radicals in cell senescence: Are they signal transducers?
-
Passos, J. F. & Von Zglinicki, T. Oxygen free radicals in cell senescence: are they signal transducers? Free Radic. Res. 40, 1277-1283 (2006).
-
(2006)
Free Radic. Res
, vol.40
, pp. 1277-1283
-
-
Passos, J.F.1
Von Zglinicki, T.2
-
44
-
-
0035917814
-
Mitochondrial permeability transition and oxidative stress
-
Kowaltowski, A. J., Castilho, R. F. & Vercesi, A. E. Mitochondrial permeability transition and oxidative stress. FEBS Lett. 495, 12-15 (2001).
-
(2001)
FEBS Lett
, vol.495
, pp. 12-15
-
-
Kowaltowski, A.J.1
Castilho, R.F.2
Vercesi, A.E.3
-
45
-
-
85047695800
-
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
-
Trinei, M. et al. A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene 21, 3872-3878 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 3872-3878
-
-
Trinei, M.1
-
46
-
-
33846817351
-
Shc
-
Shc. Science 315, 659-663 (2007).
-
(2007)
Science
, vol.315
, pp. 659-663
-
-
Pinton, P.1
-
47
-
-
0033581704
-
Shc adaptor protein controls oxidative stress response and life span in mammals
-
Shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402, 309-313 (1999).
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
-
48
-
-
22744447211
-
Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 122, 221-233 (2005).
-
(2005)
Cell
, vol.122
, pp. 221-233
-
-
Giorgio, M.1
-
49
-
-
0022974413
-
Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA
-
Bloch, C.A. & Ausubel, F.M. Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA. J. Bacteriol. 168, 795-798 (1986).
-
(1986)
J. Bacteriol
, vol.168
, pp. 795-798
-
-
Bloch, C.A.1
Ausubel, F.M.2
-
50
-
-
0027293919
-
Effects of Cu-Zn superoxide dismutase overexpression of life span and resistance to oxidative stress in transgenic Drosophila melanogaster
-
Orr, W. C. & Sohal, R. S. Effects of Cu-Zn superoxide dismutase overexpression of life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 301, 34-40 (1993).
-
(1993)
Arch. Biochem. Biophys
, vol.301
, pp. 34-40
-
-
Orr, W.C.1
Sohal, R.S.2
-
51
-
-
0028012335
-
Glutathione peroxidase compensates for the hypersensitivity of Cu,Zn-superoxide dismutase overproducers to oxidant stress
-
Amstad, P., Moret, R. & Cerutti, P. Glutathione peroxidase compensates for the hypersensitivity of Cu,Zn-superoxide dismutase overproducers to oxidant stress. J. Biol. Chem. 269, 1606-1609 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 1606-1609
-
-
Amstad, P.1
Moret, R.2
Cerutti, P.3
-
52
-
-
0036361291
-
Animal models for mitochondrial disease
-
Wallace, D. C. Animal models for mitochondrial disease. Methods Mol. Biol. 197, 3-54 (2002).
-
(2002)
Methods Mol. Biol
, vol.197
, pp. 3-54
-
-
Wallace, D.C.1
-
53
-
-
2942555103
-
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard ageing in the nematode Caenorhabditis elegans
-
Keaney, M., Matthijssens, F., Sharpe, M., Vanfleteren, J. & Gems, D. Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard ageing in the nematode Caenorhabditis elegans. Free Radic. Biol. Med. 37, 239-250 (2004).
-
(2004)
Free Radic. Biol. Med
, vol.37
, pp. 239-250
-
-
Keaney, M.1
Matthijssens, F.2
Sharpe, M.3
Vanfleteren, J.4
Gems, D.5
-
54
-
-
0036233805
-
Therapeutics against mitochondrial oxidative stress in animal models of ageing
-
Melov, S. Therapeutics against mitochondrial oxidative stress in animal models of ageing. Ann. NY Acad. Sci. 959, 330-340 (2002).
-
(2002)
Ann. NY Acad. Sci
, vol.959
, pp. 330-340
-
-
Melov, S.1
-
55
-
-
23844483173
-
Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: Implications for Parkinson disease
-
Peng, J., Stevenson, F. F., Doctrow, S. R. & Andersen, J. K. Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease. J. Biol. Chem. 280, 29194-29198 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 29194-29198
-
-
Peng, J.1
Stevenson, F.F.2
Doctrow, S.R.3
Andersen, J.K.4
-
56
-
-
12344276944
-
Superoxide dismutase evolution and life span regulation
-
Landis, G. N. & Tower, J. Superoxide dismutase evolution and life span regulation. Mech. Ageing Dev. 126, 365-379 (2005).
-
(2005)
Mech. Ageing Dev
, vol.126
, pp. 365-379
-
-
Landis, G.N.1
Tower, J.2
-
57
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner, S. E. et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308, 1909-1911 (2005).
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
-
58
-
-
8144229685
-
Shc gene protects against age-related endothelial dysfunction
-
Shc gene protects against age-related endothelial dysfunction. Circulation 110, 2889-2895 (2004).
-
(2004)
Circulation
, vol.110
, pp. 2889-2895
-
-
Francia, P.1
-
59
-
-
33748288148
-
Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress
-
Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress. Diabetes 55, 1642-1650 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 1642-1650
-
-
Menini, S.1
-
60
-
-
0037452461
-
Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
-
Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc. Natl Acad. Sci. USA 18, 2112-2116 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.18
, pp. 2112-2116
-
-
Napoli, C.1
-
61
-
-
33746207801
-
Shc gene
-
Shc gene. Circ. Res. 99, 42-52 (2006).
-
(2006)
Circ. Res
, vol.99
, pp. 42-52
-
-
Rota, M.1
-
62
-
-
4644293695
-
The GH/IGF-I axis and longevity
-
Holzenberger M. The GH/IGF-I axis and longevity. Eur. J. Endocrinol. 151 (Suppl. 1), S23-S27 (2004).
-
(2004)
Eur. J. Endocrinol
, vol.151
, Issue.SUPPL. 1
-
-
Holzenberger, M.1
-
63
-
-
33644959683
-
Mitochondrial respiration and reactive oxygen species in mitochondrial ageing mutants
-
Sedensky, M. M. & Morgan, P. G. Mitochondrial respiration and reactive oxygen species in mitochondrial ageing mutants. Exp. Gerontol. 41, 237-245 (2006).
-
(2006)
Exp. Gerontol
, vol.41
, pp. 237-245
-
-
Sedensky, M.M.1
Morgan, P.G.2
-
64
-
-
0030070430
-
Somatic mutagenesis and antimutagenesis in ageing research
-
Martin, G. M. Somatic mutagenesis and antimutagenesis in ageing research. Mutat. Res. 350, 35-41 (1996).
-
(1996)
Mutat. Res
, vol.350
, pp. 35-41
-
-
Martin, G.M.1
-
65
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovich, A. et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429, 417-423 (2004).
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovich, A.1
-
66
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian ageing
-
Kujoth, G. C. et al. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian ageing. Science 309, 481-484 (2005).
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
-
67
-
-
0037387682
-
Genotype and age influence the effect of caloric intake on mortality
-
Forster, M. J., Morris, P. & Sohal, R. S. Genotype and age influence the effect of caloric intake on mortality. FASEB J. 17, 690-692 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 690-692
-
-
Forster, M.J.1
Morris, P.2
Sohal, R.S.3
-
68
-
-
33646731782
-
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction
-
Bonkowski, M. S., Rocha, J. S., Masternak, M. M., Al Regaiey, K. A. & Bartke, A. Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc. Natl Acad. Sci. USA 103, 7901-7905 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 7901-7905
-
-
Bonkowski, M.S.1
Rocha, J.S.2
Masternak, M.M.3
Al Regaiey, K.A.4
Bartke, A.5
-
69
-
-
32444450707
-
The effect of dietary restriction on mitochondrial protein density and flight muscle mitochondrial morphology in Drosophila
-
Magwere, T. et al. The effect of dietary restriction on mitochondrial protein density and flight muscle mitochondrial morphology in Drosophila. J. Gerontol. A. Biol. Sci. Med. Sci. 61, 36-47 (2004).
-
(2004)
J. Gerontol. A. Biol. Sci. Med. Sci
, vol.61
, pp. 36-47
-
-
Magwere, T.1
-
70
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
Lopez-Lluch, G. et al. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc. Natl Acad. Sci. USA 103, 1768-1773 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 1768-1773
-
-
Lopez-Lluch, G.1
-
71
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli, E. et al. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310, 314-317 (2005).
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
-
73
-
-
0012898236
-
Action of food restriction in delaying the ageing process
-
Masaro, E. J., Yu, B. P. & Bertrand, H. A. Action of food restriction in delaying the ageing process. Proc. Natl Acad. Sci. USA 79, 4239-4241 (1982).
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 4239-4241
-
-
Masaro, E.J.1
Yu, B.P.2
Bertrand, H.A.3
-
74
-
-
0026640250
-
Energy metabolism and ageing: A lifelong study of Fischer 344 rats
-
McCarter, R. J. & Palmer, J. Energy metabolism and ageing: a lifelong study of Fischer 344 rats. Am. J. Physiol. 263, E448-E452 (1992).
-
(1992)
Am. J. Physiol
, vol.263
-
-
McCarter, R.J.1
Palmer, J.2
-
75
-
-
0037112027
-
2 production and oxidative DNA damage in the heart of food-restricted rats
-
2 production and oxidative DNA damage in the heart of food-restricted rats. Microsc. Res. Tech. 59, 273-277 (2002).
-
(2002)
Microsc. Res. Tech
, vol.59
, pp. 273-277
-
-
Gredilla, R.1
Lopez-Torres, M.2
Barja, G.3
-
76
-
-
15444362142
-
Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria
-
Hagopian, K. et al. Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria. Am. J. Physiol. Endocrinol. Metab. 288, E674-E684 (2005).
-
(2005)
Am. J. Physiol. Endocrinol. Metab
, vol.288
-
-
Hagopian, K.1
-
77
-
-
14644408160
-
Caloric restriction augments ROS defence in S. cerevisiae, by a Sir2p independent mechanism
-
Agarwal, S., Sharma, S., Agrawal, V. & Roy, N. Caloric restriction augments ROS defence in S. cerevisiae, by a Sir2p independent mechanism. Free Radic. Res. 39, 55-62 (2005).
-
(2005)
Free Radic. Res
, vol.39
, pp. 55-62
-
-
Agarwal, S.1
Sharma, S.2
Agrawal, V.3
Roy, N.4
-
78
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae life span by increasing respiration
-
Lin, S. J. et al. Calorie restriction extends Saccharomyces cerevisiae life span by increasing respiration. Nature 418, 344-348 (2002).
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
-
80
-
-
0025614206
-
Oxidative stress as a causal factor in differentiation and ageing: A unifying hypothesis
-
Sohal, R. S. & Allen, R. G. Oxidative stress as a causal factor in differentiation and ageing: a unifying hypothesis. Exp. Gerontol. 25, 499-522 (1990).
-
(1990)
Exp. Gerontol
, vol.25
, pp. 499-522
-
-
Sohal, R.S.1
Allen, R.G.2
|