메뉴 건너뛰기




Volumn 16, Issue 7, 2009, Pages 966-975

Life and death partners: Apoptosis, autophagy and the cross-talk between them

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; ARSENIC TRIOXIDE; BECLIN 1; CELL PROTEIN; CERAMIDE; DEATH ASSOCIATED PROTEIN KINASE; IMATINIB; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN ATG5; PROTEIN BCL 2; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

EID: 67549142261     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.33     Document Type: Review
Times cited : (1081)

References (95)
  • 1
    • 56749170677 scopus 로고    scopus 로고
    • Autophagic cell death: The story of a misnomer
    • Kroemer G, Levine B. Autophagic cell death: The story of a misnomer. Nat Rev Mol Cell Biol 2008; 9: 1004-1010.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 1004-1010
    • Kroemer, G.1    Levine, B.2
  • 2
    • 20444363122 scopus 로고    scopus 로고
    • The coordinate regulation of the p53 and mTOR pathways in cells
    • Feng Z, Zhang H, Levine AJ, Jin S. The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci USA 2005; 102 8204-8209.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8204-8209
    • Feng, Z.1    Zhang, H.2    Levine, A.J.3    Jin, S.4
  • 4
    • 34547624687 scopus 로고    scopus 로고
    • A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells
    • Park K, Lee S, Kim T, Lee H, Lee C, Kim E et al. A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. Cancer Res 2007; 67: 7327-7334.
    • (2007) Cancer Res , vol.67 , pp. 7327-7334
    • Park, K.1    Lee, S.2    Kim, T.3    Lee, H.4    Lee, C.5    Kim, E.6
  • 5
    • 33846077612 scopus 로고    scopus 로고
    • Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1
    • Qian W, Liu J, Jin J, Ni W, Xu W. Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1. Leuk Res 2007; 31: 329-339.
    • (2007) Leuk Res , vol.31 , pp. 329-339
    • Qian, W.1    Liu, J.2    Jin, J.3    Ni, W.4    Xu, W.5
  • 6
    • 36849031824 scopus 로고    scopus 로고
    • Imatinib interferes with survival of multi drug resistant Kaposi's sarcoma cells
    • Basciani S, Vona R, Matarrese P, Ascione B, Mariani S, Cauda R et al Imatinib interferes with survival of multi drug resistant Kaposi's sarcoma cells. FEBS Lett 2007; 581: 5897-5903.
    • (2007) FEBS Lett , vol.581 , pp. 5897-5903
    • Basciani, S.1    Vona, R.2    Matarrese, P.3    Ascione, B.4    Mariani, S.5    Cauda, R.6
  • 7
    • 33749243499 scopus 로고    scopus 로고
    • Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells
    • Yang W, Monroe J, Zhang Y, George D, Bremer E, Li H. Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells. Cancer Lett 2006; 243: 217-227.
    • (2006) Cancer Lett , vol.243 , pp. 217-227
    • Yang, W.1    Monroe, J.2    Zhang, Y.3    George, D.4    Bremer, E.5    Li, H.6
  • 8
    • 48249148726 scopus 로고    scopus 로고
    • Vitamin K2 induces-autophagy and apoptosis simultaneously in leukemia cells
    • Yokoyama T, Miyazawa K, Naito M, Toyotake J, Tauchi T, Itoh M et al Vitamin K2 induces-autophagy and apoptosis simultaneously in leukemia cells. Autophagy 2008; 4: 629-640.
    • (2008) Autophagy , vol.4 , pp. 629-640
    • Yokoyama, T.1    Miyazawa, K.2    Naito, M.3    Toyotake, J.4    Tauchi, T.5    Itoh, M.6
  • 9
    • 56349138968 scopus 로고    scopus 로고
    • DAPk is a key mediator of endoplasmic reticulum stress-induced caspase activation and autophagy
    • Gozuacik D, Bialik S, Raveh T, Shohat G, Mizushima N, Yoshimori T et al. DAPk is a key mediator of endoplasmic reticulum stress-induced caspase activation and autophagy. Cell Death Diff 2008; 15: 1875-1886.
    • (2008) Cell Death Diff , vol.15 , pp. 1875-1886
    • Gozuacik, D.1    Bialik, S.2    Raveh, T.3    Shohat, G.4    Mizushima, N.5    Yoshimori, T.6
  • 11
    • 34548068863 scopus 로고    scopus 로고
    • Apoptosis and autophagy in photoreceptors exposed to oxidative stress
    • Kunchithapautham K, Rohrer B. Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy 2007; 3: 433-441.
    • (2007) Autophagy , vol.3 , pp. 433-441
    • Kunchithapautham, K.1    Rohrer, B.2
  • 13
    • 33947497050 scopus 로고    scopus 로고
    • Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
    • Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X et al. Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem 2007; 282: 4702-4710.
    • (2007) J Biol Chem , vol.282 , pp. 4702-4710
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Hou, Y.F.4    Melan, M.A.5    Chen, X.6
  • 14
    • 0032870475 scopus 로고    scopus 로고
    • Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution
    • Xue L, Fletcher G, Tolkovsky A. Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution. Mol Cell Neurosci 1999; 14: 180-198.
    • (1999) Mol Cell Neurosci , vol.14 , pp. 180-198
    • Xue, L.1    Fletcher, G.2    Tolkovsky, A.3
  • 15
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
    • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304: 1500-1502.
    • (2004) Science , vol.304 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6
  • 16
    • 33645521571 scopus 로고    scopus 로고
    • Autophagic programmed cell death by selective catalase degradation
    • Yu L, Wan F, Dutta S, Welsh S, Liu Z, Freundt E et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci USA 2006; 103: 4952-4957.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 4952-4957
    • Yu, L.1    Wan, F.2    Dutta, S.3    Welsh, S.4    Liu, Z.5    Freundt, E.6
  • 18
    • 33745845126 scopus 로고    scopus 로고
    • Autophagy contributes to caspase-independent macrophage cell death
    • Xu Y, Kim SO, Li Y, Han J. Autophagy contributes to caspase-independent macrophage cell death. J Biol Chem 2006; 281: 19179-19187.
    • (2006) J Biol Chem , vol.281 , pp. 19179-19187
    • Xu, Y.1    Kim, S.O.2    Li, Y.3    Han, J.4
  • 19
    • 33846211417 scopus 로고    scopus 로고
    • ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
    • Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H et al. ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ 2007; 14: 230-239.
    • (2007) Cell Death Differ , vol.14 , pp. 230-239
    • Kouroku, Y.1    Fujita, E.2    Tanida, I.3    Ueno, T.4    Isoai, A.5    Kumagai, H.6
  • 20
    • 33845459165 scopus 로고    scopus 로고
    • Autophagy is activated for cell survival after endoplasmic reticulum stress
    • Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006; 26: 9220-9231.
    • (2006) Mol Cell Biol , vol.26 , pp. 9220-9231
    • Ogata, M.1    Hino, S.2    Saito, A.3    Morikawa, K.4    Kondo, S.5    Kanemoto, S.6
  • 21
    • 33845480131 scopus 로고    scopus 로고
    • Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
    • Bemales S, McDonald K, Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 2006; 4: E423.
    • (2006) PLoS Biol , vol.4
    • Bemales, S.1    McDonald, K.2    Walter, P.3
  • 22
    • 20444459545 scopus 로고    scopus 로고
    • Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene
    • Castino R, Davies J, Beaucourt S, Isidoro C, Murphy D. Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene. FASEB J 2005; 19: 1021-1023.
    • (2005) FASEB J , vol.19 , pp. 1021-1023
    • Castino, R.1    Davies, J.2    Beaucourt, S.3    Isidoro, C.4    Murphy, D.5
  • 23
    • 38049123578 scopus 로고    scopus 로고
    • Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress
    • Ullman E, Fan Y, Stawowczyk M, Chen H, Yue Z, Zong W. Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress. Cell Death Differ 2007; 15: 422-425.
    • (2007) Cell Death Differ , vol.15 , pp. 422-425
    • Ullman, E.1    Fan, Y.2    Stawowczyk, M.3    Chen, H.4    Yue, Z.5    Zong, W.6
  • 24
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation induced and constitutive autophagy in Atg7-deficient mice
    • Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I et al. Impairment of starvation induced and constitutive autophagy in Atg7-deficient mice. J. Cell Biol 2005; 169: 425-434.
    • (2005) J. Cell Biol , vol.169 , pp. 425-434
    • Komatsu, M.1    Waguri, S.2    Ueno, T.3    Iwata, J.4    Murata, S.5    Tanida, I.6
  • 25
    • 11144245626 scopus 로고    scopus 로고
    • The role of autophagy during the early neonatal starvation period
    • Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T et al The role of autophagy during the early neonatal starvation period. Nature 2004; 432: 1032-1036.
    • (2004) Nature , vol.432 , pp. 1032-1036
    • Kuma, A.1    Hatano, M.2    Matsui, M.3    Yamamoto, A.4    Nakaya, H.5    Yoshimori, T.6
  • 27
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum JJ, Bauer DE, Kong M, Harris MH, Li G, Lindsten T et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005; 120: 237-248.
    • (2005) Cell , vol.120 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, G.5    Lindsten, T.6
  • 28
    • 41449109334 scopus 로고    scopus 로고
    • Induction of autophagy during extracellular matrix detachment promotes cell survival
    • Fung C, Lock R, Gao S, Salas E, Debnath J. Induction of autophagy during extracellular matrix detachment promotes cell survival. Mol Biol Cell 2008; 19: 797-806.
    • (2008) Mol Biol Cell , vol.19 , pp. 797-806
    • Fung, C.1    Lock, R.2    Gao, S.3    Salas, E.4    Debnath, J.5
  • 29
    • 34347404887 scopus 로고    scopus 로고
    • Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
    • Karantza-Wadsworth V, Patel S, Kravchuk 0, Chen G, Mathew R, Jin S et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007; 21: 1621-1635.
    • (2007) Genes Dev , vol.21 , pp. 1621-1635
    • Karantza-Wadsworth, V.1    Patel, S.2    Kravchuk 03    Chen, G.4    Mathew, R.5    Jin, S.6
  • 30
    • 34249863298 scopus 로고    scopus 로고
    • Autophagy suppresses tumor progression by limiting chromosomal instability
    • Mathew R, Kongara S, Beaudoin B, Karp C, Bray K, Degenhardt K et al Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 2007; 21: 1367-1381.
    • (2007) Genes Dev , vol.21 , pp. 1367-1381
    • Mathew, R.1    Kongara, S.2    Beaudoin, B.3    Karp, C.4    Bray, K.5    Degenhardt, K.6
  • 31
    • 0035863399 scopus 로고    scopus 로고
    • A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
    • Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 2001; 61 439-444.
    • (2001) Cancer Res , vol.61 , pp. 439-444
    • Paglin, S.1    Hollister, T.2    Delohery, T.3    Hackett, N.4    McMahill, M.5    Sphicas, E.6
  • 32
    • 21444442926 scopus 로고    scopus 로고
    • Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells
    • Ito H, Daido S, Kanzawa T, Kondo S, Kondo Y. Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells. Int J 0ncol 2005; 26: 1401-1410.
    • (2005) Int J 0ncol , vol.26 , pp. 1401-1410
    • Ito, H.1    Daido, S.2    Kanzawa, T.3    Kondo, S.4    Kondo, Y.5
  • 34
    • 34347394714 scopus 로고    scopus 로고
    • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance
    • Carew J, Nawrocki S, Kahue C, Zhang H, Yang C, Chung L et al. Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance. Blood 2007; 110: 313-322.
    • (2007) Blood , vol.110 , pp. 313-322
    • Carew, J.1    Nawrocki, S.2    Kahue, C.3    Zhang, H.4    Yang, C.5    Chung, L.6
  • 35
    • 34249658435 scopus 로고    scopus 로고
    • Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells
    • Nguyen T, Subramanian I, Kelekar A, Ramakrishnan S. Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells. Blood 2007; 109: 4793-4802.
    • (2007) Blood , vol.109 , pp. 4793-4802
    • Nguyen, T.1    Subramanian, I.2    Kelekar, A.3    Ramakrishnan, S.4
  • 36
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy gene-dependent clearance of apoptotic cells during embryonic development
    • Qu X, Zou Z, Sun Q, Luby-Phelps K, Cheng P, Hogan R et al. Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 2007; 128: 931-946.
    • (2007) Cell , vol.128 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3    Luby-Phelps, K.4    Cheng, P.5    Hogan, R.6
  • 37
    • 0037193474 scopus 로고    scopus 로고
    • DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
    • Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol 2002; 157: 455-468.
    • (2002) J Cell Biol , vol.157 , pp. 455-468
    • Inbal, B.1    Bialik, S.2    Sabanay, I.3    Shani, G.4    Kimchi, A.5
  • 38
    • 33750058023 scopus 로고    scopus 로고
    • Upstream of the mammalian target of rapamycin: Do all roads pass through mTOR?
    • Corradetti M, Guan K, Upstream of the mammalian target of rapamycin: Do all roads pass through mTOR? Oncogene 2006; 25: 6347-6360.
    • (2006) Oncogene , vol.25 , pp. 6347-6360
    • Corradetti, M.1    Guan, K.2
  • 39
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin D, Sabatini D. Defining the role of mTOR in cancer. Cancer Cell 2007; 12: 9-22.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.1    Sabatini, D.2
  • 40
    • 54549089738 scopus 로고    scopus 로고
    • Hypoxia signaling through mTOR and the unfolded protein response in cancer
    • Wouters B, Koritzinsky M. Hypoxia signaling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 2008; 8: 851-864.
    • (2008) Nat Rev Cancer , vol.8 , pp. 851-864
    • Wouters, B.1    Koritzinsky, M.2
  • 41
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • Song G, Ouyang G, Bao S. The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 2005; 9: 59-71.
    • (2005) J Cell Mol Med , vol.9 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 42
    • 34547209343 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
    • McCubrey J, Steelman L, Chappell W, Abrams S, Wong E, Chang F et al Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007; 1773: 1263-1284.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1263-1284
    • McCubrey, J.1    Steelman, L.2    Chappell, W.3    Abrams, S.4    Wong, E.5    Chang, F.6
  • 43
    • 0034881019 scopus 로고    scopus 로고
    • Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPk survival signals
    • Ballif B, Blenis J. Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPk survival signals. Cell Growth Diff 2001; 12: 397-408.
    • (2001) Cell Growth Diff , vol.12 , pp. 397-408
    • Ballif, B.1    Blenis, J.2
  • 44
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004; 23: 2891-2906.
    • (2004) Oncogene , vol.23 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 45
    • 38049098543 scopus 로고    scopus 로고
    • The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
    • Hanada T, Noda N, Satomi Y, Ichimura Y, Fujioka Y, Takao T et al. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 2007; 282: 37298-37302.
    • (2007) J Biol Chem , vol.282 , pp. 37298-37302
    • Hanada, T.1    Noda, N.2    Satomi, Y.3    Ichimura, Y.4    Fujioka, Y.5    Takao, T.6
  • 46
    • 43949143804 scopus 로고    scopus 로고
    • The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
    • Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 2008; 19: 2092-2100.
    • (2008) Mol Biol Cell , vol.19 , pp. 2092-2100
    • Fujita, N.1    Itoh, T.2    Omori, H.3    Fukuda, M.4    Noda, T.5    Yoshimori, T.6
  • 48
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335: 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 49
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122: 927-939.
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 50
    • 48249092267 scopus 로고    scopus 로고
    • Bcl-2 family members: Dual regulators of apoptosis and autophagy
    • Levine B, Sinha S, Kroemer G. Bcl-2 family members: Dual regulators of apoptosis and autophagy. Autophagy 2008; 4: 6.
    • (2008) Autophagy , vol.4 , pp. 6
    • Levine, B.1    Sinha, S.2    Kroemer, G.3
  • 51
    • 27144544082 scopus 로고    scopus 로고
    • Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
    • Takahashi Y, Karbowski M, Yamaguchi H, Kazi A, Wu J, Sebti S et al Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. Mol Cell Biol 2005; 25: 9369-9382.
    • (2005) Mol Cell Biol , vol.25 , pp. 9369-9382
    • Takahashi, Y.1    Karbowski, M.2    Yamaguchi, H.3    Kazi, A.4    Wu, J.5    Sebti, S.6
  • 52
    • 54449099779 scopus 로고    scopus 로고
    • BCL-XL and UVRAG cause a monomer-dimer switch in beclin1
    • Noble C, Dong J, Manser E, Song H. BCL-XL and UVRAG cause a monomer-dimer switch in beclin1. J Biol Chem 2008; 283: 26274-26282.
    • (2008) J Biol Chem , vol.283 , pp. 26274-26282
    • Noble, C.1    Dong, J.2    Manser, E.3    Song, H.4
  • 53
    • 61849102389 scopus 로고    scopus 로고
    • DAPk-mediated phosphorylation on the BH3 domain of Beclin-1 promotes dissociation of Beclin-1 from Bcl-XL to induce autophagy
    • Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M et al. DAPk-mediated phosphorylation on the BH3 domain of Beclin-1 promotes dissociation of Beclin-1 from Bcl-XL to induce autophagy. EMBO Rep 2009; 10: 285-292.
    • (2009) EMBO Rep , vol.10 , pp. 285-292
    • Zalckvar, E.1    Berissi, H.2    Mizrachy, L.3    Idelchuk, Y.4    Koren, I.5    Eisenstein, M.6
  • 54
    • 44949237240 scopus 로고    scopus 로고
    • JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
    • Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30: 678-688.
    • (2008) Mol Cell , vol.30 , pp. 678-688
    • Wei, Y.1    Pattingre, S.2    Sinha, S.3    Bassik, M.4    Levine, B.5
  • 55
    • 43649104579 scopus 로고    scopus 로고
    • Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
    • Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB et al Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 2008; 283: 10892-10903.
    • (2008) J Biol Chem , vol.283 , pp. 10892-10903
    • Zhang, H.1    Bosch-Marce, M.2    Shimoda, L.A.3    Tan, Y.S.4    Baek, J.H.5    Wesley, J.B.6
  • 56
    • 36148954660 scopus 로고    scopus 로고
    • The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer
    • Mellor H, Harris A. The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer. Cancer Metastasis Rev 2007; 26: 553-566.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 553-566
    • Mellor, H.1    Harris, A.2
  • 57
    • 33847048316 scopus 로고    scopus 로고
    • Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
    • Zhu J, Horbinski C, Guo F, Watkins S, Uchiyama Y, Chu C. Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol 2007; 170: 75-86.
    • (2007) Am J Pathol , vol.170 , pp. 75-86
    • Zhu, J.1    Horbinski, C.2    Guo, F.3    Watkins, S.4    Uchiyama, Y.5    Chu, C.6
  • 58
    • 47249094223 scopus 로고    scopus 로고
    • Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
    • Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R. Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Diff 2008; 15: 1318-1329.
    • (2008) Cell Death Diff , vol.15 , pp. 1318-1329
    • Scarlatti, F.1    Maffei, R.2    Beau, I.3    Codogno, P.4    Ghidoni, R.5
  • 60
    • 0033575320 scopus 로고    scopus 로고
    • Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A
    • Ruvolo PP, Deng X, Ito T, Carr BK, May WS. Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A. J Biol Chem 1999; 274: 20296-20300.
    • (1999) J Biol Chem , vol.274 , pp. 20296-20300
    • Ruvolo, P.P.1    Deng, X.2    Ito, T.3    Carr, B.K.4    May, W.S.5
  • 61
    • 1542353401 scopus 로고    scopus 로고
    • Control of apoptosis by p53
    • Fridman JS, Lowe SW. Control of apoptosis by p53. Oncogene 2003; 22: 9030-9040.
    • (2003) Oncogene , vol.22 , pp. 9030-9040
    • Fridman, J.S.1    Lowe, S.W.2
  • 62
    • 33745885329 scopus 로고    scopus 로고
    • DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
    • Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison P et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126: 121-134.
    • (2006) Cell , vol.126 , pp. 121-134
    • Crighton, D.1    Wilkinson, S.2    O'Prey, J.3    Syed, N.4    Smith, P.5    Harrison, P.6
  • 64
    • 33646523798 scopus 로고    scopus 로고
    • A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death
    • Reef S, Zalckvar E, Shifman O, Bialik S, Sabanay H, Oren M et al. A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Mol Cell 2006; 22: 463-475.
    • (2006) Mol Cell , vol.22 , pp. 463-475
    • Reef, S.1    Zalckvar, E.2    Shifman, O.3    Bialik, S.4    Sabanay, H.5    Oren, M.6
  • 65
    • 35348853088 scopus 로고    scopus 로고
    • The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein
    • Reef S, Shifman O, Oren M, Kimchi A. The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein. Oncogene 2007; 26: 6677-6683.
    • (2007) Oncogene , vol.26 , pp. 6677-6683
    • Reef, S.1    Shifman, O.2    Oren, M.3    Kimchi, A.4
  • 66
    • 39049144417 scopus 로고    scopus 로고
    • p53-dependent and p53-independent activation of autophagy by ARF
    • Abida W, Gu W. p53-dependent and p53-independent activation of autophagy by ARF. Cancer Res 2008; 68: 352-357.
    • (2008) Cancer Res , vol.68 , pp. 352-357
    • Abida, W.1    Gu, W.2
  • 67
    • 53549087505 scopus 로고    scopus 로고
    • Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53 independent autophagy
    • Reef S, Kimchi A. Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53 independent autophagy. Autophagy 2008; 4: 866-869.
    • (2008) Autophagy , vol.4 , pp. 866-869
    • Reef, S.1    Kimchi, A.2
  • 68
    • 59149096565 scopus 로고    scopus 로고
    • ARF induces autophagy by virtue of interaction with Bcl-xl
    • Pimkina J, Humbey O, Zilfou J, Jarnik M, Murphy M. ARF induces autophagy by virtue of interaction with Bcl-xl. J Biol Chem 2009; 284: 2803-2810.
    • (2009) J Biol Chem , vol.284 , pp. 2803-2810
    • Pimkina, J.1    Humbey, O.2    Zilfou, J.3    Jarnik, M.4    Murphy, M.5
  • 69
    • 33746359639 scopus 로고    scopus 로고
    • The death-associated protein kinases: Structure, function and beyond
    • Bialik S, Kimchi A. The death-associated protein kinases: Structure, function and beyond. Annu Rev Biochem 2006; 75: 189-210.
    • (2006) Annu Rev Biochem , vol.75 , pp. 189-210
    • Bialik, S.1    Kimchi, A.2
  • 70
    • 0037078325 scopus 로고    scopus 로고
    • DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals
    • Wang WJ, Kuo JC, Yao CC, Chen RH. DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals. J Cell Biol 2002; 159: 169-179.
    • (2002) J Cell Biol , vol.159 , pp. 169-179
    • Wang, W.J.1    Kuo, J.C.2    Yao, C.C.3    Chen, R.H.4
  • 71
    • 32644448252 scopus 로고    scopus 로고
    • The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway
    • Kuo J, Wang W, Yao C, Wu P, Chen R. The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway. J Cell Biol 2006; 172: 619-631.
    • (2006) J Cell Biol , vol.172 , pp. 619-631
    • Kuo, J.1    Wang, W.2    Yao, C.3    Wu, P.4    Chen, R.5
  • 72
    • 0028831202 scopus 로고
    • Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death
    • Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev 1995; 9: 15-30.
    • (1995) Genes Dev , vol.9 , pp. 15-30
    • Deiss, L.P.1    Feinstein, E.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 73
    • 34548421950 scopus 로고    scopus 로고
    • Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation
    • Kang C, You Y, Avery L. Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation. Genes Dev 2007; 21 2161-2171.
    • (2007) Genes Dev , vol.21 , pp. 2161-2171
    • Kang, C.1    You, Y.2    Avery, L.3
  • 74
    • 2942740790 scopus 로고    scopus 로고
    • DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation
    • Bialik S, Bresnick AR, Kimchi A. DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation. Cell Death Differ 2004; 11: 631-644.
    • (2004) Cell Death Differ , vol.11 , pp. 631-644
    • Bialik, S.1    Bresnick, A.R.2    Kimchi, A.3
  • 75
    • 0346121431 scopus 로고    scopus 로고
    • Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase
    • Kuo JC, Lin JR, Staddon JM, Hosoya H, Chen RH. Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase. J Cell Sci 2003; 116: 4777-4790.
    • (2003) J Cell Sci , vol.116 , pp. 4777-4790
    • Kuo, J.C.1    Lin, J.R.2    Staddon, J.M.3    Hosoya, H.4    Chen, R.H.5
  • 76
    • 43949145220 scopus 로고    scopus 로고
    • DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing
    • Harrison B, Kraus M, Burch L, Stevens C, Craig A, Gordon-Weeks P et al. DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. J Biol Chem 2008; 283: 9999-10014.
    • (2008) J Biol Chem , vol.283 , pp. 9999-10014
    • Harrison, B.1    Kraus, M.2    Burch, L.3    Stevens, C.4    Craig, A.5    Gordon-Weeks, P.6
  • 77
    • 33750120717 scopus 로고    scopus 로고
    • The MAP1 family of microtubule-associated proteins
    • Halpain S, Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol 2006; 7: 224.
    • (2006) Genome Biol , vol.7 , pp. 224
    • Halpain, S.1    Dehmelt, L.2
  • 78
    • 0035141040 scopus 로고    scopus 로고
    • DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation
    • Raveh T, Droguett G, Horwitz MS, DePinho RA, Kimchi A. DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nat Cell Biol 2001; 3: 1-7.
    • (2001) Nat Cell Biol , vol.3 , pp. 1-7
    • Raveh, T.1    Droguett, G.2    Horwitz, M.S.3    DePinho, R.A.4    Kimchi, A.5
  • 79
    • 13444311622 scopus 로고    scopus 로고
    • Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK
    • Chen CH, Wang WJ, Kuo JC, Tsai HC, Lin JR, Chang ZF et al. Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK. EMBO J 2005; 24: 294-304.
    • (2005) EMBO J , vol.24 , pp. 294-304
    • Chen, C.H.1    Wang, W.J.2    Kuo, J.C.3    Tsai, H.C.4    Lin, J.R.5    Chang, Z.F.6
  • 80
    • 35548946698 scopus 로고    scopus 로고
    • DAP-kinase regulates JNK signaling by binding and activating protein kinase D under oxidative stress
    • Eisenberg-Lerner A, Kimchi A. DAP-kinase regulates JNK signaling by binding and activating protein kinase D under oxidative stress. Cell Death Differ 2007; 14: 1908-1915.
    • (2007) Cell Death Differ , vol.14 , pp. 1908-1915
    • Eisenberg-Lerner, A.1    Kimchi, A.2
  • 81
    • 36749050812 scopus 로고    scopus 로고
    • Life and death decisions by the E2F transcription factors
    • Iaquinta P, Lees J. Life and death decisions by the E2F transcription factors. Curr Opin Cell Biol 2007; 19: 649-657.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 649-657
    • Iaquinta, P.1    Lees, J.2
  • 82
    • 49649121765 scopus 로고    scopus 로고
    • E2F1 regulates autophagy and the transcription of autophagy genes
    • Polager S, Ofir M, Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 2008; 27: 4860-4864.
    • (2008) Oncogene , vol.27 , pp. 4860-4864
    • Polager, S.1    Ofir, M.2    Ginsberg, D.3
  • 83
    • 33645905712 scopus 로고    scopus 로고
    • Autophagy, mitochondrial quality control, and oncogenesis
    • Jin S. Autophagy, mitochondrial quality control, and oncogenesis. Autophagy 2006; 2: 80-84.
    • (2006) Autophagy , vol.2 , pp. 80-84
    • Jin, S.1
  • 84
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber T, Osmanian C, Jacks T, Housman D, Koch C, Lowe S et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996; 379: 88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.1    Osmanian, C.2    Jacks, T.3    Housman, D.4    Koch, C.5    Lowe, S.6
  • 85
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G et al Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006; 10: 51-64.
    • (2006) Cancer Cell , vol.10 , pp. 51-64
    • Degenhardt, K.1    Mathew, R.2    Beaudoin, B.3    Bray, K.4    Anderson, D.5    Chen, G.6
  • 86
    • 48249090416 scopus 로고    scopus 로고
    • Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer
    • Kim K, Hwang M, Moretti L, Jaboin J, Cha Y, Lu B. Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 2008; 4: 659-668.
    • (2008) Autophagy , vol.4 , pp. 659-668
    • Kim, K.1    Hwang, M.2    Moretti, L.3    Jaboin, J.4    Cha, Y.5    Lu, B.6
  • 87
    • 24644447853 scopus 로고    scopus 로고
    • Enhanced radiation damage of tumor vasculature by mTOR inhibitors
    • Shinohara E, Cao C, Niermann K, Mu Y, Zeng F, Hallahan D et al. Enhanced radiation damage of tumor vasculature by mTOR inhibitors. Oncogene 2005; 24: 5414-5422.
    • (2005) Oncogene , vol.24 , pp. 5414-5422
    • Shinohara, E.1    Cao, C.2    Niermann, K.3    Mu, Y.4    Zeng, F.5    Hallahan, D.6
  • 88
    • 57649138440 scopus 로고    scopus 로고
    • Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2
    • Bae D, Lu S, Taglienti C, Mercurio A. Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2. J Biol Chem 2008; 283: 28074-28080.
    • (2008) J Biol Chem , vol.283 , pp. 28074-28080
    • Bae, D.1    Lu, S.2    Taglienti, C.3    Mercurio, A.4
  • 89
    • 3042515471 scopus 로고    scopus 로고
    • DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death
    • Bialik S, Kimchi A. DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death. Semin Cancer Biol 2004; 14: 283-294.
    • (2004) Semin Cancer Biol , vol.14 , pp. 283-294
    • Bialik, S.1    Kimchi, A.2
  • 90
    • 33745751085 scopus 로고    scopus 로고
    • Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
    • Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh B et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 2006; 8: 688-699.
    • (2006) Nat Cell Biol , vol.8 , pp. 688-699
    • Liang, C.1    Feng, P.2    Ku, B.3    Dotan, I.4    Canaani, D.5    Oh, B.6
  • 91
    • 45049083880 scopus 로고    scopus 로고
    • Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
    • Kim M, Jeong E, Ahn C, Kim S, Lee S, Yoo N. Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol 2008; 39: 1059-1063.
    • (2008) Hum Pathol , vol.39 , pp. 1059-1063
    • Kim, M.1    Jeong, E.2    Ahn, C.3    Kim, S.4    Lee, S.5    Yoo, N.6
  • 93
    • 1242296021 scopus 로고    scopus 로고
    • Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability
    • Ionov Y, Nowak N, Perucho M, Markowitz S, Cowell J. Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability. Oncogene 2004; 23: 639-645.
    • (2004) Oncogene , vol.23 , pp. 639-645
    • Ionov, Y.1    Nowak, N.2    Perucho, M.3    Markowitz, S.4    Cowell, J.5
  • 94
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • Itakura E, Kishi C, Inoue K, Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 2008; 19: 5360-5372.
    • (2008) Mol Biol Cell , vol.19 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 95
    • 46449120732 scopus 로고    scopus 로고
    • Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
    • Liang C, Lee J, Inn K, Gack M, Li Q, Roberts E et al. Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nat Cell Biol 2008; 10: 776-787.
    • (2008) Nat Cell Biol , vol.10 , pp. 776-787
    • Liang, C.1    Lee, J.2    Inn, K.3    Gack, M.4    Li, Q.5    Roberts, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.