메뉴 건너뛰기




Volumn 53, Issue , 2014, Pages 547-557

The epigenetic landscape of T-cell acute lymphoblastic leukemia

Author keywords

DNA methylation; Epigenetics; Histone modification; Leukemia; T ALL

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE DEMETHYLASE; HISTONE METHYLTRANSFERASE; POLYCOMB GROUP PROTEIN; HISTONE;

EID: 84905036207     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.04.015     Document Type: Review
Times cited : (21)

References (140)
  • 2
    • 79954414897 scopus 로고    scopus 로고
    • Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
    • Y.S. Ang, S.Y. Tsai, D.F. Lee, J. Monk, J. Su, and K. Ratnakumar et al. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network Cell 145 2011 183 197
    • (2011) Cell , vol.145 , pp. 183-197
    • Ang, Y.S.1    Tsai, S.Y.2    Lee, D.F.3    Monk, J.4    Su, J.5    Ratnakumar, K.6
  • 3
    • 0025642707 scopus 로고
    • Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity
    • P.D. Aplan, D.P. Lombardi, A.M. Ginsberg, J. Cossman, V.L. Bertness, and I.R. Kirsch Disruption of the human SCL locus by illegitimate V-(D)-J recombinase activity Science 250 1990 1426 1429 (Pubitemid 120031866)
    • (1990) Science , vol.250 , Issue.4986 , pp. 1426-1429
    • Aplan, P.D.1    Lombardi, D.P.2    Ginsberg, A.M.3    Cossman, J.4    Bertness, V.L.5    Kirsch, I.R.6
  • 6
    • 0027479344 scopus 로고
    • Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: A Pediatric Oncology Group study
    • R.O. Bash, W.M. Crist, J.J. Shuster, M.P. Link, M. Amylon, and J. Pullen et al. Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study Blood 81 1993 2110 2117 (Pubitemid 23106726)
    • (1993) Blood , vol.81 , Issue.8 , pp. 2110-2117
    • Bash, R.O.1    Crist, W.M.2    Shuster, J.J.3    Link, M.P.4    Amylon, M.5    Pullen, J.6    Carroll, A.J.7    Buchanan, G.R.8    Smith, R.G.9    Baer, R.10
  • 7
    • 0031035406 scopus 로고    scopus 로고
    • Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia
    • A. Batova, M.B. Diccianni, J.C. Yu, T. Nobori, M.P. Link, and J. Pullen et al. Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia Cancer Res 57 1997 832 836 (Pubitemid 27098004)
    • (1997) Cancer Research , vol.57 , Issue.5 , pp. 832-836
    • Batova, A.1    Diccianni, M.B.2    Yu, J.C.3    Nobori, T.4    Link, M.P.5    Pullen, J.6    Yu, A.L.7
  • 8
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome - Biological and translational implications
    • S.B. Baylin, and P.A. Jones A decade of exploring the cancer epigenome - biological and translational implications Nat Rev Cancer 11 2011 726 734
    • (2011) Nat Rev Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 9
    • 80053194516 scopus 로고    scopus 로고
    • PHF6 deletions may cause Borjeson-Forssman-Lehmann syndrome in females
    • S. Berland, K. Alme, A. Brendehaug, G. Houge, and R. Hovland PHF6 deletions may cause Borjeson-Forssman-Lehmann syndrome in females Mol Syndromol 1 2011 294 300
    • (2011) Mol Syndromol , vol.1 , pp. 294-300
    • Berland, S.1    Alme, K.2    Brendehaug, A.3    Houge, G.4    Hovland, R.5
  • 11
    • 84877000591 scopus 로고    scopus 로고
    • Relapsed childhood acute lymphoblastic leukaemia
    • D. Bhojwani, and C.H. Pui Relapsed childhood acute lymphoblastic leukaemia Lancet Oncol 14 2013 e205 e217
    • (2013) Lancet Oncol , vol.14
    • Bhojwani, D.1    Pui, C.H.2
  • 13
    • 84878807245 scopus 로고    scopus 로고
    • Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia
    • M. Borssen, L. Palmqvist, K. Karrman, J. Abrahamsson, M. Behrendtz, and J. Heldrup et al. Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia PLoS One 8 2013 e65373
    • (2013) PLoS One , vol.8 , pp. 65373
    • Borssen, M.1    Palmqvist, L.2    Karrman, K.3    Abrahamsson, J.4    Behrendtz, M.5    Heldrup, J.6
  • 14
    • 72949085978 scopus 로고    scopus 로고
    • Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance
    • E.E. Bram, M. Stark, S. Raz, and Y.G. Assaraf Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance Neoplasia 11 2009 1359 1370
    • (2009) Neoplasia , vol.11 , pp. 1359-1370
    • Bram, E.E.1    Stark, M.2    Raz, S.3    Assaraf, Y.G.4
  • 15
    • 84555207349 scopus 로고    scopus 로고
    • Dnmt3a is essential for hematopoietic stem cell differentiation
    • G.A. Challen, D. Sun, M. Jeong, M. Luo, J. Jelinek, and J.S. Berg et al. Dnmt3a is essential for hematopoietic stem cell differentiation Nat Genet 44 2012 23 31
    • (2012) Nat Genet , vol.44 , pp. 23-31
    • Challen, G.A.1    Sun, D.2    Jeong, M.3    Luo, M.4    Jelinek, J.5    Berg, J.S.6
  • 16
    • 77957078794 scopus 로고    scopus 로고
    • T-cell acute lymphoblastic leukemia in association with Borjeson-Forssman-Lehmann syndrome due to a mutation in PHF6
    • M.M. Chao, M.A. Todd, U. Kontny, K. Neas, M.J. Sullivan, and A.G. Hunter et al. T-cell acute lymphoblastic leukemia in association with Borjeson-Forssman-Lehmann syndrome due to a mutation in PHF6 Pediatr Blood Cancer 55 2010 722 724
    • (2010) Pediatr Blood Cancer , vol.55 , pp. 722-724
    • Chao, M.M.1    Todd, M.A.2    Kontny, U.3    Neas, K.4    Sullivan, M.J.5    Hunter, A.G.6
  • 17
    • 77953995002 scopus 로고    scopus 로고
    • Covalent histone modifications - Miswritten, misinterpreted and mis-erased in human cancers
    • P. Chi, C.D. Allis, and G.G. Wang Covalent histone modifications - miswritten, misinterpreted and mis-erased in human cancers Nat Rev Cancer 10 2010 457 469
    • (2010) Nat Rev Cancer , vol.10 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 20
    • 58749095816 scopus 로고    scopus 로고
    • Early T-cell precursor leukaemia: A subtype of very high-risk acute lymphoblastic leukaemia
    • E. Coustan-Smith, C.G. Mullighan, M. Onciu, F.G. Behm, S.C. Raimondi, and D. Pei et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia Lancet Oncol 10 2009 147 156
    • (2009) Lancet Oncol , vol.10 , pp. 147-156
    • Coustan-Smith, E.1    Mullighan, C.G.2    Onciu, M.3    Behm, F.G.4    Raimondi, S.C.5    Pei, D.6
  • 22
    • 79960058024 scopus 로고    scopus 로고
    • Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor
    • S.R. Daigle, E.J. Olhava, C.A. Therkelsen, C.R. Majer, C.J. Sneeringer, and J. Song et al. Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor Cancer Cell 20 2011 53 65
    • (2011) Cancer Cell , vol.20 , pp. 53-65
    • Daigle, S.R.1    Olhava, E.J.2    Therkelsen, C.A.3    Majer, C.R.4    Sneeringer, C.J.5    Song, J.6
  • 23
    • 80054806708 scopus 로고    scopus 로고
    • P53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia
    • C. Davies, L.A. Hogarth, P.A. Dietrich, P.S. Bachmann, K.L. Mackenzie, and A.G. Hall et al. p53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia J Biol Chem 286 2011 37639 37650
    • (2011) J Biol Chem , vol.286 , pp. 37639-37650
    • Davies, C.1    Hogarth, L.A.2    Dietrich, P.A.3    Bachmann, P.S.4    Mackenzie, K.L.5    Hall, A.G.6
  • 24
    • 80052445151 scopus 로고    scopus 로고
    • Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36
    • S.F. de Almeida, A.R. Grosso, F. Koch, R. Fenouil, S. Carvalho, and J. Andrade et al. Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36 Nat Struct Mol Biol 18 2011 977 983
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 977-983
    • De Almeida, S.F.1    Grosso, A.R.2    Koch, F.3    Fenouil, R.4    Carvalho, S.5    Andrade, J.6
  • 25
    • 84873084751 scopus 로고    scopus 로고
    • Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia
    • K. De Keersmaecker, Z.K. Atak, N. Li, C. Vicente, S. Patchett, and T. Girardi et al. Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia Nat Genet 45 2013 186 190
    • (2013) Nat Genet , vol.45 , pp. 186-190
    • De Keersmaecker, K.1    Atak, Z.K.2    Li, N.3    Vicente, C.4    Patchett, S.5    Girardi, T.6
  • 26
    • 34548644772 scopus 로고    scopus 로고
    • The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing
    • DOI 10.1016/j.cell.2007.08.019, PII S0092867407010823
    • F. De Santa, M.G. Totaro, E. Prosperini, S. Notarbartolo, G. Testa, and G. Natoli The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing Cell 130 2007 1083 1094 (Pubitemid 47410272)
    • (2007) Cell , vol.130 , Issue.6 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5    Natoli, G.6
  • 28
    • 84885393469 scopus 로고    scopus 로고
    • Transcriptional regulation by Polycomb group proteins
    • L. Di Croce, and K. Helin Transcriptional regulation by Polycomb group proteins Nat Struct Mol Biol 20 2013 1147 1155
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 1147-1155
    • Di Croce, L.1    Helin, K.2
  • 29
    • 77955085750 scopus 로고    scopus 로고
    • Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
    • T. Ernst, A.J. Chase, J. Score, C.E. Hidalgo-Curtis, C. Bryant, and A.V. Jones et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders Nat Genet 42 2010 722 726
    • (2010) Nat Genet , vol.42 , pp. 722-726
    • Ernst, T.1    Chase, A.J.2    Score, J.3    Hidalgo-Curtis, C.E.4    Bryant, C.5    Jones, A.V.6
  • 33
    • 33751328324 scopus 로고    scopus 로고
    • The Börjeson-Forssman-Lehman syndrome (BFLS, MIM)
    • DOI 10.1038/sj.ejhg.5201639, PII 5201639
    • J. Gecz, G. Turner, J. Nelson, and M. Partington The Borjeson-Forssman- Lehman syndrome (BFLS, MIM #301900) Eur J Hum Genet 14 2006 1233 1237 (Pubitemid 44804027)
    • (2006) European Journal of Human Genetics , vol.14 , Issue.12 , pp. 1233-1237
    • Gecz, J.1    Turner, G.2    Nelson, J.3    Partington, M.4
  • 34
    • 0038707589 scopus 로고    scopus 로고
    • Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia
    • DOI 10.1038/sj.onc.1206313
    • P.A. Goodman, N. Burkhardt, B. Juran, H.E. Tibbles, and F.M. Uckun Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia Oncogene 22 2003 2504 2514 (Pubitemid 36560733)
    • (2003) Oncogene , vol.22 , Issue.16 , pp. 2504-2514
    • Goodman, P.A.1    Burkhardt, N.2    Juran, B.3    Tibbles, H.E.4    Uckun, F.M.5
  • 35
    • 84857195696 scopus 로고    scopus 로고
    • Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
    • J. Grembecka, S. He, A. Shi, T. Purohit, A.G. Muntean, and R.J. Sorenson et al. Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia Nat Chem Biol 8 2012 277 284
    • (2012) Nat Chem Biol , vol.8 , pp. 277-284
    • Grembecka, J.1    He, S.2    Shi, A.3    Purohit, T.4    Muntean, A.G.5    Sorenson, R.J.6
  • 36
    • 84873732313 scopus 로고    scopus 로고
    • The molecular profile of adult T-cell acute lymphoblastic leukemia: Mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL
    • V. Grossmann, C. Haferlach, S. Weissmann, A. Roller, S. Schindela, and F. Poetzinger et al. The molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL Genes Chromosomes Cancer 52 2013 410 422
    • (2013) Genes Chromosomes Cancer , vol.52 , pp. 410-422
    • Grossmann, V.1    Haferlach, C.2    Weissmann, S.3    Roller, A.4    Schindela, S.5    Poetzinger, F.6
  • 37
    • 77956240492 scopus 로고    scopus 로고
    • Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia
    • A. Gutierrez, S.E. Dahlberg, D.S. Neuberg, J. Zhang, R. Grebliunaite, and T. Sanda et al. Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia J Clin Oncol 28 2010 3816 3823
    • (2010) J Clin Oncol , vol.28 , pp. 3816-3823
    • Gutierrez, A.1    Dahlberg, S.E.2    Neuberg, D.S.3    Zhang, J.4    Grebliunaite, R.5    Sanda, T.6
  • 38
    • 1642358490 scopus 로고    scopus 로고
    • Linking the epigenetic 'language' of covalent histone modifications to cancer
    • DOI 10.1038/sj.bjc.6601575
    • S.B. Hake, A. Xiao, and C.D. Allis Linking the epigenetic 'language' of covalent histone modifications to cancer Br J Cancer 90 2004 761 769 (Pubitemid 38406583)
    • (2004) British Journal of Cancer , vol.90 , Issue.4 , pp. 761-769
    • Hake, S.B.1    Xiao, A.2    Allis, C.D.3
  • 39
    • 0036847620 scopus 로고    scopus 로고
    • Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes
    • DOI 10.1016/S0092-8674(02)01005-X
    • A.H. Hassan, P. Prochasson, K.E. Neely, S.C. Galasinski, M. Chandy, and M.J. Carrozza et al. Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes Cell 111 2002 369 379 (Pubitemid 35345152)
    • (2002) Cell , vol.111 , Issue.3 , pp. 369-379
    • Hassan, A.H.1    Prochasson, P.2    Neely, K.E.3    Galasinski, S.C.4    Chandy, M.5    Carrozza, M.J.6    Workman, J.L.7
  • 40
    • 0025894715 scopus 로고
    • Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
    • M. Hatano, C.W. Roberts, M. Minden, W.M. Crist, and S.J. Korsmeyer Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia Science 253 1991 79 82 (Pubitemid 21917124)
    • (1991) Science , vol.253 , Issue.5015 , pp. 79-82
    • Hatano, M.1    Roberts, C.W.M.2    Minden, M.3    Crist, W.M.4    Korsmeyer, S.J.5
  • 41
    • 84880219451 scopus 로고    scopus 로고
    • Early T-cell precursor acute lymphoblastic leukaemia
    • J.E. Haydu, and A.A. Ferrando Early T-cell precursor acute lymphoblastic leukaemia Curr Opin Hematol 20 2013 369 373
    • (2013) Curr Opin Hematol , vol.20 , pp. 369-373
    • Haydu, J.E.1    Ferrando, A.A.2
  • 42
    • 84886808679 scopus 로고    scopus 로고
    • Chromatin proteins and modifications as drug targets
    • K. Helin, and D. Dhanak Chromatin proteins and modifications as drug targets Nature 502 2013 480 488
    • (2013) Nature , vol.502 , pp. 480-488
    • Helin, K.1    Dhanak, D.2
  • 43
    • 79953735093 scopus 로고    scopus 로고
    • Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia
    • I. Homminga, R. Pieters, A.W. Langerak, J.J. de Rooi, A. Stubbs, and M. Verstegen et al. Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia Cancer Cell 19 2011 484 497
    • (2011) Cancer Cell , vol.19 , pp. 484-497
    • Homminga, I.1    Pieters, R.2    Langerak, A.W.3    De Rooi, J.J.4    Stubbs, A.5    Verstegen, M.6
  • 45
    • 77649239655 scopus 로고    scopus 로고
    • Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling
    • M. Hu, X.J. Sun, Y.L. Zhang, Y. Kuang, C.Q. Hu, and W.L. Wu et al. Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling Proc Natl Acad Sci U S A 107 2010 2956 2961
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2956-2961
    • Hu, M.1    Sun, X.J.2    Zhang, Y.L.3    Kuang, Y.4    Hu, C.Q.5    Wu, W.L.6
  • 46
    • 79954626107 scopus 로고    scopus 로고
    • Epigenetic regulation of PAX5 expression in acute T-cell lymphoblastic leukemia
    • G. Hutter, M. Kaiser, M. Neumann, M. Mossner, D. Nowak, and C.D. Baldus et al. Epigenetic regulation of PAX5 expression in acute T-cell lymphoblastic leukemia Leuk Res 35 2011 614 619
    • (2011) Leuk Res , vol.35 , pp. 614-619
    • Hutter, G.1    Kaiser, M.2    Neumann, M.3    Mossner, M.4    Nowak, D.5    Baldus, C.D.6
  • 47
    • 84878341989 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • H. Inaba, M. Greaves, and C.G. Mullighan Acute lymphoblastic leukaemia Lancet 381 2013 1943 1955
    • (2013) Lancet , vol.381 , pp. 1943-1955
    • Inaba, H.1    Greaves, M.2    Mullighan, C.G.3
  • 48
    • 33847219608 scopus 로고    scopus 로고
    • Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
    • I. Issaeva, Y. Zonis, T. Rozovskaia, K. Orlovsky, C.M. Croce, and T. Nakamura et al. Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth Mol Cell Biol 27 2007 1889 1903
    • (2007) Mol Cell Biol , vol.27 , pp. 1889-1903
    • Issaeva, I.1    Zonis, Y.2    Rozovskaia, T.3    Orlovsky, K.4    Croce, C.M.5    Nakamura, T.6
  • 49
    • 2942612219 scopus 로고    scopus 로고
    • P300/CBP and cancer
    • DOI 10.1038/sj.onc.1207118
    • N.G. Iyer, H. Ozdag, and C. Caldas p300/CBP and cancer Oncogene 23 2004 4225 4231 (Pubitemid 38758588)
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4225-4231
    • Iyer, N.G.1    Ozdag, H.2    Caldas, C.3
  • 50
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc- induced apoptosis via INK4a/ARF
    • DOI 10.1101/gad.13.20.2678
    • J.J. Jacobs, B. Scheijen, J.W. Voncken, K. Kieboom, A. Berns, and M. van Lohuizen Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF Genes Dev 13 1999 2678 2690 (Pubitemid 29508555)
    • (1999) Genes and Development , vol.13 , Issue.20 , pp. 2678-2690
    • Jacobs, J.J.L.1    Scheijen, B.2    Voncken, J.-W.3    Kieboom, K.4    Berns, A.5    Van Lohuizen, M.6
  • 51
    • 84891372425 scopus 로고    scopus 로고
    • Large conserved domains of low DNA methylation maintained by Dnmt3a
    • M. Jeong, D. Sun, M. Luo, Y. Huang, G.A. Challen, and B. Rodriguez et al. Large conserved domains of low DNA methylation maintained by Dnmt3a Nat Genet 46 2014 17 23
    • (2014) Nat Genet , vol.46 , pp. 17-23
    • Jeong, M.1    Sun, D.2    Luo, M.3    Huang, Y.4    Challen, G.A.5    Rodriguez, B.6
  • 52
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: Islands, start sites, gene bodies and beyond
    • P.A. Jones Functions of DNA methylation: islands, start sites, gene bodies and beyond Nat Rev Genet 13 2012 484 492
    • (2012) Nat Rev Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 53
    • 33847065486 scopus 로고    scopus 로고
    • The Epigenomics of Cancer
    • DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
    • P.A. Jones, and S.B. Baylin The epigenomics of cancer Cell 128 2007 683 692 (Pubitemid 46273572)
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 54
    • 0037291915 scopus 로고    scopus 로고
    • Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes
    • DOI 10.1016/S1097-2765(03)00034-0
    • S. Kadam, and B.M. Emerson Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes Mol Cell 11 2003 377 389 (Pubitemid 36293832)
    • (2003) Molecular Cell , vol.11 , Issue.2 , pp. 377-389
    • Kadam, S.1    Emerson, B.M.2
  • 55
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • C. Kandoth, M.D. McLellan, F. Vandin, K. Ye, B. Niu, and C. Lu et al. Mutational landscape and significance across 12 major cancer types Nature 502 2013 333 339
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3    Ye, K.4    Niu, B.5    Lu, C.6
  • 56
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • T. Kouzarides Chromatin modifications and their function Cell 128 2007 693 705 (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 57
    • 84856728415 scopus 로고    scopus 로고
    • DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: Insights into CpG island methylator phenotype in T-ALL
    • M.D. Kraszewska, M. Dawidowska, N.S. Larmonie, M. Kosmalska, L. Sedek, and M. Szczepaniak et al. DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL Leukemia 26 2012 367 371
    • (2012) Leukemia , vol.26 , pp. 367-371
    • Kraszewska, M.D.1    Dawidowska, M.2    Larmonie, N.S.3    Kosmalska, M.4    Sedek, L.5    Szczepaniak, M.6
  • 59
    • 79960844248 scopus 로고    scopus 로고
    • Cancer biology and NuRD: A multifaceted chromatin remodelling complex
    • A.Y. Lai, and P.A. Wade Cancer biology and NuRD: a multifaceted chromatin remodelling complex Nat Rev Cancer 11 2011 588 596
    • (2011) Nat Rev Cancer , vol.11 , pp. 588-596
    • Lai, A.Y.1    Wade, P.A.2
  • 61
    • 84855833698 scopus 로고    scopus 로고
    • Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome
    • D. Lederer, B. Grisart, M.C. Digilio, V. Benoit, M. Crespin, and S.C. Ghariani et al. Deletion of KDM6A, a histone demethylase interacting with MLL2, in three patients with Kabuki syndrome Am J Hum Genet 90 2012 119 124
    • (2012) Am J Hum Genet , vol.90 , pp. 119-124
    • Lederer, D.1    Grisart, B.2    Digilio, M.C.3    Benoit, V.4    Crespin, M.5    Ghariani, S.C.6
  • 63
    • 84855957128 scopus 로고    scopus 로고
    • UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program
    • S. Lee, J.W. Lee, and S.K. Lee UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program Dev Cell 22 2012 25 37
    • (2012) Dev Cell , vol.22 , pp. 25-37
    • Lee, S.1    Lee, J.W.2    Lee, S.K.3
  • 64
    • 84876943255 scopus 로고    scopus 로고
    • The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSalpha
    • F. Li, G. Mao, D. Tong, J. Huang, L. Gu, and W. Yang et al. The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSalpha Cell 153 2013 590 600
    • (2013) Cell , vol.153 , pp. 590-600
    • Li, F.1    Mao, G.2    Tong, D.3    Huang, J.4    Gu, L.5    Yang, W.6
  • 65
    • 84873359541 scopus 로고    scopus 로고
    • Somatic mutations of PHF6 in patients with chronic myeloid leukemia in blast crisis
    • X. Li, H. Yao, Z. Chen, Q. Wang, Y. Zhao, and S. Chen Somatic mutations of PHF6 in patients with chronic myeloid leukemia in blast crisis Leuk Lymphoma 54 2013 671 672
    • (2013) Leuk Lymphoma , vol.54 , pp. 671-672
    • Li, X.1    Yao, H.2    Chen, Z.3    Wang, Q.4    Zhao, Y.5    Chen, S.6
  • 66
    • 70149123507 scopus 로고    scopus 로고
    • Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias
    • Y.H. Lin, P.M. Kakadia, Y. Chen, Y.Q. Li, A.J. Deshpande, and C. Buske et al. Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias Blood 114 2009 651 658
    • (2009) Blood , vol.114 , pp. 651-658
    • Lin, Y.H.1    Kakadia, P.M.2    Chen, Y.3    Li, Y.Q.4    Deshpande, A.J.5    Buske, C.6
  • 68
    • 84865112255 scopus 로고    scopus 로고
    • The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming
    • A.A. Mansour, O. Gafni, L. Weinberger, A. Zviran, M. Ayyash, and Y. Rais et al. The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming Nature 488 2012 409 413
    • (2012) Nature , vol.488 , pp. 409-413
    • Mansour, A.A.1    Gafni, O.2    Weinberger, L.3    Zviran, A.4    Ayyash, M.5    Rais, Y.6
  • 69
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • R. Margueron, and D. Reinberg The Polycomb complex PRC2 and its mark in life Nature 469 2011 343 349
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 71
    • 0024564420 scopus 로고
    • The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein
    • E.A. McGuire, R.D. Hockett, K.M. Pollock, M.F. Bartholdi, S.J. O'Brien, and S.J. Korsmeyer The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein Mol Cell Biol 9 1989 2124 2132 (Pubitemid 19117813)
    • (1989) Molecular and Cellular Biology , vol.9 , Issue.5 , pp. 2124-2132
    • McGuire, E.A.1    Hockett, R.D.2    Pollock, K.M.3    Bartholdi, M.F.4    O'Brien, S.J.5    Korsmeyer, S.J.6
  • 72
    • 0024308990 scopus 로고
    • Lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif
    • DOI 10.1016/0092-8674(89)90404-2
    • J.D. Mellentin, S.D. Smith, and M.L. Cleary lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif Cell 58 1989 77 83 (Pubitemid 19180080)
    • (1989) Cell , vol.58 , Issue.1 , pp. 77-83
    • Mellentin, J.D.1    Smith, S.D.2    Cleary, M.L.3
  • 74
    • 78649263390 scopus 로고    scopus 로고
    • Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression
    • S.A. Miller, S.E. Mohn, and A.S. Weinmann Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression Mol Cell 40 2010 594 605
    • (2010) Mol Cell , vol.40 , pp. 594-605
    • Miller, S.A.1    Mohn, S.E.2    Weinmann, A.S.3
  • 75
    • 77957154350 scopus 로고    scopus 로고
    • Throwing the cancer switch: Reciprocal roles of polycomb and trithorax proteins
    • A.A. Mills Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins Nat Rev Cancer 10 2010 669 682
    • (2010) Nat Rev Cancer , vol.10 , pp. 669-682
    • Mills, A.A.1
  • 76
    • 79960064353 scopus 로고    scopus 로고
    • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
    • K. Moran-Crusio, L. Reavie, A. Shih, O. Abdel-Wahab, D. Ndiaye-Lobry, and C. Lobry et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation Cancer Cell 20 2011 11 24
    • (2011) Cancer Cell , vol.20 , pp. 11-24
    • Moran-Crusio, K.1    Reavie, L.2    Shih, A.3    Abdel-Wahab, O.4    Ndiaye-Lobry, D.5    Lobry, C.6
  • 77
    • 75749124332 scopus 로고    scopus 로고
    • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
    • R.D. Morin, N.A. Johnson, T.M. Severson, A.J. Mungall, J. An, and R. Goya et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin Nat Genet 42 2010 181 185
    • (2010) Nat Genet , vol.42 , pp. 181-185
    • Morin, R.D.1    Johnson, N.A.2    Severson, T.M.3    Mungall, A.J.4    An, J.5    Goya, R.6
  • 79
    • 84881041250 scopus 로고    scopus 로고
    • Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations
    • M. Neumann, S. Heesch, C. Schlee, S. Schwartz, N. Gokbuget, and D. Hoelzer et al. Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations Blood 121 2013 4749 4752
    • (2013) Blood , vol.121 , pp. 4749-4752
    • Neumann, M.1    Heesch, S.2    Schlee, C.3    Schwartz, S.4    Gokbuget, N.5    Hoelzer, D.6
  • 81
    • 77955087290 scopus 로고    scopus 로고
    • Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
    • G. Nikoloski, S.M. Langemeijer, R.P. Kuiper, R. Knops, M. Massop, and E.R. Tonnissen et al. Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes Nat Genet 42 2010 665 667
    • (2010) Nat Genet , vol.42 , pp. 665-667
    • Nikoloski, G.1    Langemeijer, S.M.2    Kuiper, R.P.3    Knops, R.4    Massop, M.5    Tonnissen, E.R.6
  • 82
  • 83
    • 0029886810 scopus 로고    scopus 로고
    • Interaction of the co-activator CBP with Myb proteins: Effects on Myb-specific transactivation and on the cooperativity with NF-M
    • M. Oelgeschlager, R. Janknecht, J. Krieg, S. Schreek, and B. Luscher Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M EMBO J 15 1996 2771 2780 (Pubitemid 26176254)
    • (1996) EMBO Journal , vol.15 , Issue.11 , pp. 2771-2780
    • Oelgeschlager, M.1    Janknecht, R.2    Krieg, J.3    Schreek, S.4    Luscher, B.5
  • 84
    • 33748207226 scopus 로고    scopus 로고
    • Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L
    • DOI 10.1038/ncb1464, PII NCB1464
    • Y. Okada, Q. Jiang, M. Lemieux, L. Jeannotte, L. Su, and Y. Zhang Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L Nat Cell Biol 8 2006 1017 1024 (Pubitemid 44314734)
    • (2006) Nature Cell Biology , vol.8 , Issue.9 , pp. 1017-1024
    • Okada, Y.1    Jiang, Q.2    Lemieux, M.3    Jeannotte, L.4    Su, L.5    Zhang, Y.6
  • 85
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • DOI 10.1016/S0092-8674(00)81656-6
    • M. Okano, D.W. Bell, D.A. Haber, and E. Li DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development Cell 99 1999 247 257 (Pubitemid 29519904)
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 86
    • 84863393263 scopus 로고    scopus 로고
    • Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
    • J.P. Patel, M. Gonen, M.E. Figueroa, H. Fernandez, Z. Sun, and J. Racevskis et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia N Engl J Med 366 2012 1079 1089
    • (2012) N Engl J Med , vol.366 , pp. 1079-1089
    • Patel, J.P.1    Gonen, M.2    Figueroa, M.E.3    Fernandez, H.4    Sun, Z.5    Racevskis, J.6
  • 87
    • 84886099830 scopus 로고    scopus 로고
    • Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer
    • C. Plass, S.M. Pfister, A.M. Lindroth, O. Bogatyrova, R. Claus, and P. Lichter Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer Nat Rev Genet 14 2013 765 780
    • (2013) Nat Rev Genet , vol.14 , pp. 765-780
    • Plass, C.1    Pfister, S.M.2    Lindroth, A.M.3    Bogatyrova, O.4    Claus, R.5    Lichter, P.6
  • 88
    • 84875217558 scopus 로고    scopus 로고
    • Polycomb-group proteins in hematopoietic stem cell regulation and hematopoietic neoplasms
    • V. Radulovic, G. de Haan, and K. Klauke Polycomb-group proteins in hematopoietic stem cell regulation and hematopoietic neoplasms Leukemia 27 2013 523 533
    • (2013) Leukemia , vol.27 , pp. 523-533
    • Radulovic, V.1    De Haan, G.2    Klauke, K.3
  • 89
    • 0020986251 scopus 로고
    • 5-Methylcytosine, gene regulation, and cancer
    • A.D. Riggs, and P.A. Jones 5-Methylcytosine, gene regulation, and cancer Adv Cancer Res 40 1983 1 30
    • (1983) Adv Cancer Res , vol.40 , pp. 1-30
    • Riggs, A.D.1    Jones, P.A.2
  • 90
    • 84877632013 scopus 로고    scopus 로고
    • An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
    • D. Rohle, J. Popovici-Muller, N. Palaskas, S. Turcan, C. Grommes, and C. Campos et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells Science 340 2013 626 630
    • (2013) Science , vol.340 , pp. 626-630
    • Rohle, D.1    Popovici-Muller, J.2    Palaskas, N.3    Turcan, S.4    Grommes, C.5    Campos, C.6
  • 91
    • 0025933456 scopus 로고
    • TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)
    • B. Royer-Pokora, U. Loos, and W.D. Ludwig TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11) Oncogene 6 1991 1887 1893 (Pubitemid 21924023)
    • (1991) Oncogene , vol.6 , Issue.10 , pp. 1887-1893
    • Royer-Pokora, B.1    Loos, U.2    Ludwig, W.-D.3
  • 93
    • 33745790132 scopus 로고    scopus 로고
    • Chromatin remodelling: The industrial revolution of DNA around histones
    • DOI 10.1038/nrm1945, PII NRM1945
    • A. Saha, J. Wittmeyer, and B.R. Cairns Chromatin remodelling: the industrial revolution of DNA around histones Nat Rev Mol Cell Biol 7 2006 437 447 (Pubitemid 44050097)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.6 , pp. 437-447
    • Saha, A.1    Wittmeyer, J.2    Cairns, B.R.3
  • 94
    • 84865520089 scopus 로고    scopus 로고
    • IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
    • M. Sasaki, C.B. Knobbe, J.C. Munger, E.F. Lind, D. Brenner, and A. Brustle et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics Nature 488 2012 656 659
    • (2012) Nature , vol.488 , pp. 656-659
    • Sasaki, M.1    Knobbe, C.B.2    Munger, J.C.3    Lind, E.F.4    Brenner, D.5    Brustle, A.6
  • 96
    • 84866912634 scopus 로고    scopus 로고
    • UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development
    • K.B. Shpargel, T. Sengoku, S. Yokoyama, and T. Magnuson UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development PLoS Genet 8 2012 e1002964
    • (2012) PLoS Genet , vol.8 , pp. 1002964
    • Shpargel, K.B.1    Sengoku, T.2    Yokoyama, S.3    Magnuson, T.4
  • 97
    • 84859295400 scopus 로고    scopus 로고
    • A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
    • C. Simon, J. Chagraoui, J. Krosl, P. Gendron, B. Wilhelm, and S. Lemieux et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia Genes Dev 26 2012 651 656
    • (2012) Genes Dev , vol.26 , pp. 651-656
    • Simon, C.1    Chagraoui, J.2    Krosl, J.3    Gendron, P.4    Wilhelm, B.5    Lemieux, S.6
  • 98
    • 84878282462 scopus 로고    scopus 로고
    • Histone variants in pluripotency and disease
    • P.J. Skene, and S. Henikoff Histone variants in pluripotency and disease Development 140 2013 2513 2524
    • (2013) Development , vol.140 , pp. 2513-2524
    • Skene, P.J.1    Henikoff, S.2
  • 99
    • 78650454078 scopus 로고    scopus 로고
    • Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
    • C.J. Sneeringer, M.P. Scott, K.W. Kuntz, S.K. Knutson, R.M. Pollock, and V.M. Richon et al. Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas Proc Natl Acad Sci U S A 107 2010 20980 20985
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20980-20985
    • Sneeringer, C.J.1    Scott, M.P.2    Kuntz, K.W.3    Knutson, S.K.4    Pollock, R.M.5    Richon, V.M.6
  • 101
    • 0036791030 scopus 로고    scopus 로고
    • Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator
    • T. Suganuma, M. Kawabata, T. Ohshima, and M.A. Ikeda Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator Proc Natl Acad Sci U S A 99 2002 13073 13078
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13073-13078
    • Suganuma, T.1    Kawabata, M.2    Ohshima, T.3    Ikeda, M.A.4
  • 103
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • M. Tahiliani, K.P. Koh, Y. Shen, W.A. Pastor, H. Bandukwala, and Y. Brudno et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 Science 324 2009 930 935
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5    Brudno, Y.6
  • 104
    • 77949874234 scopus 로고    scopus 로고
    • Histone variants - Ancient wrap artists of the epigenome
    • P.B. Talbert, and S. Henikoff Histone variants - ancient wrap artists of the epigenome Nat Rev Mol Cell Biol 11 2010 264 275
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 264-275
    • Talbert, P.B.1    Henikoff, S.2
  • 106
    • 84876470605 scopus 로고    scopus 로고
    • The histone demethylase UTX regulates stem cell migration and hematopoiesis
    • S. Thieme, T. Gyarfas, C. Richter, G. Ozhan, J. Fu, and D. Alexopoulou et al. The histone demethylase UTX regulates stem cell migration and hematopoiesis Blood 121 2013 2462 2473
    • (2013) Blood , vol.121 , pp. 2462-2473
    • Thieme, S.1    Gyarfas, T.2    Richter, C.3    Ozhan, G.4    Fu, J.5    Alexopoulou, D.6
  • 107
    • 33845417885 scopus 로고    scopus 로고
    • The cancer epigenome - Components and functional correlates
    • DOI 10.1101/gad.1464906
    • A.H. Ting, K.M. McGarvey, and S.B. Baylin The cancer epigenome - components and functional correlates Genes Dev 20 2006 3215 3231 (Pubitemid 44904843)
    • (2006) Genes and Development , vol.20 , Issue.23 , pp. 3215-3231
    • Ting, A.H.1    McGarvey, K.M.2    Baylin, S.B.3
  • 108
    • 84864627629 scopus 로고    scopus 로고
    • PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex
    • M.A. Todd, and D.J. Picketts PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex J Proteome Res 11 2012 4326 4337
    • (2012) J Proteome Res , vol.11 , pp. 4326-4337
    • Todd, M.A.1    Picketts, D.J.2
  • 109
    • 84993731455 scopus 로고    scopus 로고
    • The NOTCH signaling pathway: Role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy
    • V. Tosello, and A.A. Ferrando The NOTCH signaling pathway: role in the pathogenesis of T-cell acute lymphoblastic leukemia and implication for therapy Ther Adv Hematol 4 2013 199 210
    • (2013) Ther Adv Hematol , vol.4 , pp. 199-210
    • Tosello, V.1    Ferrando, A.A.2
  • 110
    • 10944233962 scopus 로고    scopus 로고
    • Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
    • DOI 10.1016/j.cell.2004.11.033, PII S0092867404011018
    • H. van Attikum, O. Fritsch, B. Hohn, and S.M. Gasser Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair Cell 119 2004 777 788 (Pubitemid 40017685)
    • (2004) Cell , vol.119 , Issue.6 , pp. 777-788
    • Van Attikum, H.1    Fritsch, O.2    Hohn, B.3    Gasser, S.M.4
  • 112
    • 38349068493 scopus 로고    scopus 로고
    • Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences
    • M. van Grotel, J.P. Meijerink, E.R. van Wering, A.W. Langerak, H.B. Beverloo, and J.G. Buijs-Gladdines et al. Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences Leukemia 22 2008 124 131
    • (2008) Leukemia , vol.22 , pp. 124-131
    • Van Grotel, M.1    Meijerink, J.P.2    Van Wering, E.R.3    Langerak, A.W.4    Beverloo, H.B.5    Buijs-Gladdines, J.G.6
  • 114
    • 0025863346 scopus 로고
    • Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging
    • M. van Lohuizen, S. Verbeek, B. Scheijen, E. Wientjens, H. van der Gulden, and A. Berns Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging Cell 65 1991 737 752 (Pubitemid 121001306)
    • (1991) Cell , vol.65 , Issue.5 , pp. 737-752
    • Van Lohuizen, M.1    Verbeek, S.2    Scheijen, B.3    Wientjens, E.4    Van Der Gulden, H.5    Berns, A.6
  • 116
    • 84867179824 scopus 로고    scopus 로고
    • The molecular basis of T cell acute lymphoblastic leukemia
    • P. Van Vlierberghe, and A. Ferrando The molecular basis of T cell acute lymphoblastic leukemia J Clin Investig 122 2012 3398 3406
    • (2012) J Clin Investig , vol.122 , pp. 3398-3406
    • Van Vlierberghe, P.1    Ferrando, A.2
  • 119
    • 47149084727 scopus 로고    scopus 로고
    • The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia
    • P. Van Vlierberghe, M. van Grotel, J. Tchinda, C. Lee, H.B. Beverloo, and P.J. van der Spek et al. The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia Blood 111 2008 4668 4680
    • (2008) Blood , vol.111 , pp. 4668-4680
    • Van Vlierberghe, P.1    Van Grotel, M.2    Tchinda, J.3    Lee, C.4    Beverloo, H.B.5    Van Der Spek, P.J.6
  • 120
    • 84856120332 scopus 로고    scopus 로고
    • Understanding the language of Lys36 methylation at histone H3
    • E.J. Wagner, and P.B. Carpenter Understanding the language of Lys36 methylation at histone H3 Nat Rev Mol Cell Biol 13 2012 115 126
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 115-126
    • Wagner, E.J.1    Carpenter, P.B.2
  • 121
    • 84866530722 scopus 로고    scopus 로고
    • UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity
    • C. Wang, J.E. Lee, Y.W. Cho, Y. Xiao, Q. Jin, and C. Liu et al. UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity Proc Natl Acad Sci U S A 109 2012 15324 15329
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 15324-15329
    • Wang, C.1    Lee, J.E.2    Cho, Y.W.3    Xiao, Y.4    Jin, Q.5    Liu, C.6
  • 122
    • 34548526743 scopus 로고    scopus 로고
    • Chromatin remodeling and cancer, part I: Covalent histone modifications
    • DOI 10.1016/j.molmed.2007.07.003, PII S1471491407001463
    • G.G. Wang, C.D. Allis, and P. Chi Chromatin remodeling and cancer. Part I: Covalent histone modifications Trends Mol Med 13 2007 363 372 (Pubitemid 47385381)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.9 , pp. 363-372
    • Wang, G.G.1    Allis, C.D.2    Chi, P.3
  • 123
    • 34548544648 scopus 로고    scopus 로고
    • Chromatin remodeling and cancer, part II: ATP-dependent chromatin remodeling
    • DOI 10.1016/j.molmed.2007.07.004, PII S1471491407001475
    • G.G. Wang, C.D. Allis, and P. Chi Chromatin remodeling and cancer. Part II: ATP-dependent chromatin remodeling Trends Mol Med 13 2007 373 380 (Pubitemid 47385382)
    • (2007) Trends in Molecular Medicine , vol.13 , Issue.9 , pp. 373-380
    • Wang, G.G.1    Allis, C.D.2    Chi, P.3
  • 125
    • 84873303336 scopus 로고    scopus 로고
    • PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis
    • J. Wang, J.W. Leung, Z. Gong, L. Feng, X. Shi, and J. Chen PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis J Biol Chem 288 2013 3174 3183
    • (2013) J Biol Chem , vol.288 , pp. 3174-3183
    • Wang, J.1    Leung, J.W.2    Gong, Z.3    Feng, L.4    Shi, X.5    Chen, J.6
  • 126
    • 76749139057 scopus 로고    scopus 로고
    • The histone demethylase UTX enables RB-dependent cell fate control
    • J.K. Wang, M.C. Tsai, G. Poulin, A.S. Adler, S. Chen, and H. Liu et al. The histone demethylase UTX enables RB-dependent cell fate control Genes Dev 24 2010 327 332
    • (2010) Genes Dev , vol.24 , pp. 327-332
    • Wang, J.K.1    Tsai, M.C.2    Poulin, G.3    Adler, A.S.4    Chen, S.5    Liu, H.6
  • 127
    • 79953748673 scopus 로고    scopus 로고
    • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
    • K.C. Wang, Y.W. Yang, B. Liu, A. Sanyal, R. Corces-Zimmerman, and Y. Chen et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression Nature 472 2011 120 124
    • (2011) Nature , vol.472 , pp. 120-124
    • Wang, K.C.1    Yang, Y.W.2    Liu, B.3    Sanyal, A.4    Corces-Zimmerman, R.5    Chen, Y.6
  • 128
    • 82855168107 scopus 로고    scopus 로고
    • Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia
    • Q. Wang, H. Qiu, H. Jiang, L. Wu, S. Dong, and J. Pan et al. Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia Haematologica 96 2011 1808 1814
    • (2011) Haematologica , vol.96 , pp. 1808-1814
    • Wang, Q.1    Qiu, H.2    Jiang, H.3    Wu, L.4    Dong, S.5    Pan, J.6
  • 129
    • 77953912031 scopus 로고    scopus 로고
    • Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression
    • Z. Wang, J. Song, T.A. Milne, G.G. Wang, H. Li, and C.D. Allis et al. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression Cell 141 2010 1183 1194
    • (2010) Cell , vol.141 , pp. 1183-1194
    • Wang, Z.1    Song, J.2    Milne, T.A.3    Wang, G.G.4    Li, H.5    Allis, C.D.6
  • 131
    • 84888798171 scopus 로고    scopus 로고
    • A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling
    • D. Wieczorek, N. Bogershausen, F. Beleggia, S. Steiner-Haldenstatt, E. Pohl, and Y. Li et al. A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling Hum Mol Genet 22 2013 5121 5135
    • (2013) Hum Mol Genet , vol.22 , pp. 5121-5135
    • Wieczorek, D.1    Bogershausen, N.2    Beleggia, F.3    Steiner-Haldenstatt, S.4    Pohl, E.5    Li, Y.6
  • 133
    • 46849115153 scopus 로고    scopus 로고
    • Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes
    • P. Xie, C. Tian, L. An, J. Nie, K. Lu, and G. Xing et al. Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes Cell Signal 20 2008 1671 1678
    • (2008) Cell Signal , vol.20 , pp. 1671-1678
    • Xie, P.1    Tian, C.2    An, L.3    Nie, J.4    Lu, K.5    Xing, G.6
  • 134
    • 83455181803 scopus 로고    scopus 로고
    • Somatic mutation of PHF6 gene in T-cell acute lymphoblatic leukemia, acute myelogenous leukemia and hepatocellular carcinoma
    • N.J. Yoo, Y.R. Kim, and S.H. Lee Somatic mutation of PHF6 gene in T-cell acute lymphoblatic leukemia, acute myelogenous leukemia and hepatocellular carcinoma Acta Oncol 51 2012 107 111
    • (2012) Acta Oncol , vol.51 , pp. 107-111
    • Yoo, N.J.1    Kim, Y.R.2    Lee, S.H.3
  • 135
    • 67650120109 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo
    • W. Yuan, J. Xie, C. Long, H. Erdjument-Bromage, X. Ding, and Y. Zheng et al. Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo J Biol Chem 284 2009 15701 15707
    • (2009) J Biol Chem , vol.284 , pp. 15701-15707
    • Yuan, W.1    Xie, J.2    Long, C.3    Erdjument-Bromage, H.4    Ding, X.5    Zheng, Y.6
  • 136
    • 77954487796 scopus 로고    scopus 로고
    • Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b
    • L. Zeng, Q. Zhang, S. Li, A.N. Plotnikov, M.J. Walsh, and M.M. Zhou Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b Nature 466 2010 258 262
    • (2010) Nature , vol.466 , pp. 258-262
    • Zeng, L.1    Zhang, Q.2    Li, S.3    Plotnikov, A.N.4    Walsh, M.J.5    Zhou, M.M.6
  • 137
    • 84879251172 scopus 로고    scopus 로고
    • The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain
    • C. Zhang, L.A. Mejia, J. Huang, P. Valnegri, E.J. Bennett, and J. Anckar et al. The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain Neuron 78 2013 986 993
    • (2013) Neuron , vol.78 , pp. 986-993
    • Zhang, C.1    Mejia, L.A.2    Huang, J.3    Valnegri, P.4    Bennett, E.J.5    Anckar, J.6
  • 138
    • 84862907593 scopus 로고    scopus 로고
    • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
    • J. Zhang, L. Ding, L. Holmfeldt, G. Wu, S.L. Heatley, and D. Payne-Turner et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia Nature 481 2012 157 163
    • (2012) Nature , vol.481 , pp. 157-163
    • Zhang, J.1    Ding, L.2    Holmfeldt, L.3    Wu, G.4    Heatley, S.L.5    Payne-Turner, D.6
  • 139
    • 78650304236 scopus 로고    scopus 로고
    • Charting histone modifications and the functional organization of mammalian genomes
    • V.W. Zhou, A. Goren, and B.E. Bernstein Charting histone modifications and the functional organization of mammalian genomes Nat Rev Genet 12 2011 7 18
    • (2011) Nat Rev Genet , vol.12 , pp. 7-18
    • Zhou, V.W.1    Goren, A.2    Bernstein, B.E.3
  • 140
    • 84890143329 scopus 로고    scopus 로고
    • A new face of Borjeson-Forssman-Lehmann syndrome? de novo mutations in PHF6 in seven females with a distinct phenotype
    • C. Zweier, C. Kraus, L. Brueton, T. Cole, F. Degenhardt, and H. Engels et al. A new face of Borjeson-Forssman-Lehmann syndrome? De novo mutations in PHF6 in seven females with a distinct phenotype J Med Genet 50 2013 838 847
    • (2013) J Med Genet , vol.50 , pp. 838-847
    • Zweier, C.1    Kraus, C.2    Brueton, L.3    Cole, T.4    Degenhardt, F.5    Engels, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.